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TRERF1 Gene

protein-coding GIFtS: 51

GC06M042303

transcriptional regulating factor 1
(Previous name: breast cancer anti-estrogen resistance 2 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: BCAR2)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
BCAR2 ^², ³
FLJ21198 ^²
HSA277276 ^¹, ²
OTTHUMP00000016399 ^²
RAPA ^¹, ², ³
RP1-139D8.5 ^²
TREP132 ^³
TReP-132 ^¹, ²
dJ139D8.5 ^¹, ²
rapa-1 ^²
rapa-2 ^²

Descriptions
Breast cancer anti-estrogen resistance 2 ^¹, ², ³
Transcriptional-regulating protein 132 ^³
Zinc finger protein rapa ^³
Zinc finger transcription factor TReP-132 ^³
transcriptional regulating factor 1 ^²
transcriptional regulating protein 132 ^²

External Ids
HGNC: 18273¹
Entrez Gene: 55809²
UniProtKB: Q96PN7³
Ensembl: ENSG00000124496⁷

Search outside databases for aliases for TRERF1 gene

Previous GC identifer: GC06M042242

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for TRERF1:

This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to

regulate the human gene CYP11A1. [provided by RefSeq]

UniProtKB/Swiss-Prot: TREF1_HUMAN, Q96PN7

Function: Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a

synergistic transcriptional activation of CYP11A1

Gene Wiki entry for TRERF1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the TRERF1 gene

Entrez Gene cytogenetic band: 6p21.1-p12.1 Ensembl cytogenetic band: 6p21.1 HGNC cytogenetic band: 6p21.1-p12.1

TRERF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M042303: (about GC identifiers)

Start:	42,300,647 bp from pter
End:	42,527,767 bp from pter
Size:	227,121 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000006.10 NT_007592.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: TREF1_HUMAN, Q96PN7 (See protein sequence)

Recommended Name: Transcriptional-regulating factor 1

Size: 1200 amino acids; 132256 Da

Subunit: Interacts with CREBBP and EP300

Subcellular location: Nucleus

Secondary accessions: Q05GC6 Q7Z6T2 Q7Z6T3 Q9NQ72 Q9NQ73 Q9NUN9

Alternative splicing: 5 isoforms: Q96PN7-1 Q96PN7-2 Q96PN7-3 Q96PN7-4 Q96PN7-5

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_277037.1

ENSEMBL proteins:

ENSP00000346285 ENSP00000362008 ENSP00000362005 ENSP00000362013 ENSP00000339438

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (TReP132)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0005634	nucleus	IDA	11349124

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Antibodies for TRERF1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (TReP132), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Novus Biologicals Antibodies for TRERF1

Assays for TRERF1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q96PN7

ProtoNet protein and cluster: Q96PN7

UniProtKB/Swiss-Prot: TREF1_HUMAN, Q96PN7

Similarity: Contains 3 C2H2-type zinc fingers

Similarity: Contains 1 ELM2 domain

Similarity: Contains 1 SANT domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TRERF1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TRERF1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_033501

Applied Biosystems Silencer® siRNAs for TRERF1

Sigma-Aldrich siRNA for TRERF1

Sigma-Aldrich shRNA for TRERF1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_033502
Myc/DDK tagged cDNA clone in CMV expression vector: NM_033502
untagged cDNA clones in CMV expression vector (see all 2): NM_018415

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_033502

UniProtKB/Swiss-Prot: TREF1_HUMAN, Q96PN7

Function: Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a

synergistic transcriptional activation of CYP11A1

5/7 Gene Ontology (GO) molecular function terms (links to tree view) (see all 7 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	IDA	11349124
GO:0008134	transcription factor binding	IPI	11349124
GO:0008270	zinc ion binding	IEA	--
GO:0008301	DNA bending activity	NAS	11349124
GO:0016455	RNA polymerase II transcription mediator activity	NAS	11349124

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for TRERF1

5/10 Interacting proteins for TRERF1 (ENSP00000362013³) via UniProtKB, MINT, and/or STRING (see all 10 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NR5A1	ENSP00000362690³	STRING (score=.992)
CD86	ENSP00000332049³	STRING (score=.914)
LILRB4	ENSP00000270452³	STRING (score=.879)
LILRB2	ENSP00000319960³	STRING (score=.871)
LILRB1	ENSP00000315997³	STRING (score=.86)

About this table

5/7 Gene Ontology (GO) biological process terms (links to tree view) (see all 7 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006350	transcription	IEA	--
GO:0006694	steroid biosynthetic process	NAS	11349124
GO:0006707	cholesterol catabolic process	NAS	11349124
GO:0007275	multicellular organismal development	NAS	11349124
GO:0042592	homeostatic process	NAS	11349124

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for TRERF1
1 Novoseek chemical compound relationship for TRERF1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
steroid	49.06	1	12556907 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TRERF1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TRERF1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_033501

Sigma-Aldrich siRNA for TRERF1

Sigma-Aldrich shRNA for TRERF1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_033502

REFSEQ mRNAs for TRERF1 gene:

NM_033502.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_033502

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_033502
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_033502
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_018415

Additional cDNA sequence:

AF111801.1 AF297872.1 AJ277275.1 AJ277276.1 AK002096.1 AK127493.1 AK308473.1 AM404182.1

AM404183.1 AM404259.1

10 DOTS entries:

DT.102823818 DT.100757479 DT.306866 DT.95274464 DT.100707313 DT.102823817 DT.121343431 DT.427964

DT.97837632 DT.99970910

24/96 AceView cDNA sequences (see all 96 ):

AW518695 BM701209 AW117866 BX489946 BX952047 BE645262 AA878783 AK127493

BM784836 NM_033502 BX508943 AF297872 BF724270 BU859373 BQ775152 AI299636

NM_033501 BM770293 AA811416 AA926899 AW006022 CD705237 BX504990 BX489945

highest scoring ESTs for TRERF1:

AW006022 AF297872 AA252764 AA252826 AA493429 AA804960 AA878783 AI056311 AI299636 AI375580

Unigene Cluster for TRERF1:

Transcriptional regulating factor 1

Hs.485392 [show with all ESTs]

Unigene Representative Sequence: AM404182

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for TRERF1 (see all 7 )

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4a	·	4b	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12a	·	12b	·	12c	·	12d	^	13a	·	13b
SP1:
SP2:							-
SP3:
SP4:																													-						-
SP5:

About this scheme

ECgene alternative splicing isoforms for TRERF1

5 Ensembl transcripts including schematic representations:

ENST00000354325 ENST00000372917 ENST00000372914 ENST00000372922 ENST00000340840

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

TRERF1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for TRERF1

¹ / ² / ³

8 probe-sets matching TRERF1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
73752_at²^{, 3}	U95-E	1	1.00	1.00	0.89	0.95	AI375580	0.60	1.00	0.82	1
51773_at²^{, 3}	U95-B	1	0.94	1.00	0.72	1.06	AW006022	0.80	1.00	0.91	1
233324_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AK002096	0.60	1.00	0.82	1
229016_s_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AJ277276	0.60	0.75	0.68	1
238520_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BF724270	0.40	1.00	0.76	1
233324_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
229016_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
238520_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks TRERF1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.485392
UniProtKB/Swiss-Prot: TREF1_HUMAN, Q96PN7
Tissue specificity: Highest expression was seen in thymus, testis and adrenal cortex, expressed
also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and
MCF-7 cells, low expression was seen in non-steroidogenic HepG2 and HK293 cells

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for TRERF1 gene from 5 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	TRERF1¹	--	transcriptional regulating factor 1	90.92(n) 92.79(a)	608906 XM_859860.1 XP_864953.1
chimpanzee (Pan troglodytes)	TRERF1¹	--	transcriptional regulating factor 1	97.94(n) 97.66(a)	462695 XM_518475.2 XP_518475.2
cow (Bos taurus)	TRERF1¹	--	transcriptional regulating factor 1	90.2(n) 91.15(a)	504797 XM_865759.2 XP_870852.1
mouse (Mus musculus)	Trerf1^{1, 5}	17⁵	transcriptional regulating factor 1^{1, 5}	88.39(n)¹ 90.93(a)¹	224829¹ NM_172622.1¹ NP_766210.1¹ AI429294⁵ AK035176⁵ (see all 17)
chicken (Gallus gallus)	TRERF1¹	--	transcriptional regulating factor 1	69.51(n) 69.42(a)	421386 XM_419445.2 XP_419445.2

About this table Species with no ortholog for TRERF1

ENSEMBL Gene Tree for TRERF1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for TRERF1 gene

ZNF541² C14orf43²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/1319 NCBI SNPs in TRERF1 are shown (see all 1319 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 408)

AB	SNP ID	Valid	Chr 6 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs2295275^1,2	A,C,F,H	42332524(-)	`TGTGCT/AGTTCC`	1	S/C	mis¹ ese³		18	EA NA EU WA	2964
	rs11970679^1,2	C,F,H	42438791(+)	`CAGCCA/GGGGCC`	1	--	ut5¹		4	EU EA WA	420
	rs12661255^1,2	A,C,H	42529761(+)	`GGAAAG/AGCTTC`	1	--	ng3¹		4	EU EA WA	416
	rs11751765^1,2	C,F,H	42304105(+)	`ATCATC/TCAAGA`	1	D/N	mis¹		4	EU EA WA	420
	rs16895481^1,2	F,H	42345441(+)	`GTGAAC/TGTGGC`	1	--	ut5¹ ese³		7	NA EU EA WA	562
	rs35978318^1,2	C,F	42311931(+)	`CACAGT/GTGGGC`	1	T/N	mis¹		5	NA EU EA WA	488
	rs35162277^1,2	C,F	42344016(+)	`TCCTGT/CGTCAG`	1	A/T	mis¹		5	NA EU EA WA	492
	rs17704222^1,2	C,F,H	42341496(+)	`GCTCTC/TCCATC`	1	G/G	syn¹		8	NA EU EA WA	638
	rs2295274^1,2	C,F,H	42340453(-)	`TCCCAC/TGGGGG`	1	H/H	syn¹ ese³		9	EA NA EU WA	1904
	rs7744694^1,2	A,F,H	42304190(+)	`TCCACA/GTCCTT`	1	D/D	syn¹ ese³		4	EU EA WA	418

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HapMap Linkage Disequilibrium images for TRERF1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 610322

Human Gene Mutation Database: TRERF1

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/17 PubMed articles for TRERF1 gene (see all 17 ):

A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression. (PubMed id 11349124)^{1, 2, 3, 4} Gizard F.... Hum D.W. (2001)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)^{3, 4} Beausoleil S.A....Gygi S.P. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{3, 4} Mungall A.J.... Beck S. (2003)
TReP-132 controls cell proliferation by regulating the expression of the cyclin-dependent kinase inhibitors p21WAF1/Cip1 and p27Kip1. (PubMed id 15899840)^{1, 3} Gizard F....Hum D.W. (2005)
The transcriptional regulating protein of 132 kDa (TReP-132) enhances P450scc gene transcription through interaction with steroidogenic factor-1 in human adrenal cells. (PubMed id 12101186)^{1, 3} Gizard F....Hum D.W. (2002)
The transcriptional regulating protein of 132 kDa (TReP-132) differentially influences steroidogenic pathways in human adrenal NCI-H295 cells. (PubMed id 15072559)^{1, 3} Gizard F....Hum D.W. (2004)
Function of the transcriptional regulating protein of 132 kDa (TReP-132) on human P450scc gene expression. (PubMed id 12530663)^{1, 3} Gizard F....Hum D.W. (2002)
Functional identification of genes causing estrogen independence of human breast cancer cells. (PubMed id 18351453)⁴ van Agthoven T....Dorssers L.C.J. (2009)
TReP-132 is a novel progesterone receptor coactivator required for the inhibition of breast cancer cell growth and enhancement of differentiation by progesterone. (PubMed id 17015480)³ Gizard F....Staels B. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 55809	HGNC: 18273	AceView: TRERF1	Ensembl:ENSG00000124496	euGenes: HUgn55809
ECgene: TRERF1	H-InvDB: TRERF1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for TRERF1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for TRERF1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for TRERF1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for TRERF1		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for TRERF1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Cell Culture Products		ELISAs
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Antibodies for TRERF1

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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TRERF1 Gene

protein-coding GIFtS: 51

Aliases &
Descriptions
for TRERF1

Summaries
for TRERF1

Genomic Location
for TRERF1

Proteins
for TRERF1

Protein Domains/
Families
for TRERF1

Gene Function
for TRERF1

Pathways & Interactions
for TRERF1

Drugs & Compounds
for TRERF1

Transcripts
for TRERF1

Expression
for TRERF1

Orthologs
for TRERF1

Paralogs
for TRERF1

SNPs/Variants
for TRERF1

Disorders & Mutations
for TRERF1

Medical News
for TRERF1

Publications
for TRERF1

Search for TRERF1

Genome Databases showing TRERF1

Other Databases showing TRERF1

Specialized Databases showing TRERF1

Licensable Technologies
for TRERF1

Services
for TRERF1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

TRERF1 Gene

protein-coding GIFtS: 51

Aliases & Descriptionsfor TRERF1

Summariesfor TRERF1

Genomic Locationfor TRERF1

Proteinsfor TRERF1

Protein Domains/Familiesfor TRERF1

Gene Functionfor TRERF1

Pathways & Interactionsfor TRERF1

Drugs & Compoundsfor TRERF1

Transcriptsfor TRERF1

Expression for TRERF1

Orthologsfor TRERF1

Paralogsfor TRERF1

SNPs/Variantsfor TRERF1

Disorders & Mutationsfor TRERF1

Medical Newsfor TRERF1

Publicationsfor TRERF1

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Genome Databases showing TRERF1

Other Databases showing TRERF1

Specialized Databases showing TRERF1

Licensable Technologiesfor TRERF1

Servicesfor TRERF1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for TRERF1

Summaries
for TRERF1

Genomic Location
for TRERF1

Proteins
for TRERF1

Protein Domains/
Families
for TRERF1

Gene Function
for TRERF1

Pathways & Interactions
for TRERF1

Drugs & Compounds
for TRERF1

Transcripts
for TRERF1

Expression
for TRERF1

Orthologs
for TRERF1

Paralogs
for TRERF1

SNPs/Variants
for TRERF1

Disorders & Mutations
for TRERF1

Medical News
for TRERF1

Publications
for TRERF1

Licensable Technologies
for TRERF1

Services
for TRERF1