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Aliases for BCAP29 Gene

Aliases for BCAP29 Gene

  • B-Cell Receptor-Associated Protein 29 2 3
  • BCR-Associated Protein 29 3 4
  • BAP29 3 4

External Ids for BCAP29 Gene

Previous GeneCards Identifiers for BCAP29 Gene

  • GC07P106781
  • GC07P106814
  • GC07P107007
  • GC07P107220
  • GC07P101581

Summaries for BCAP29 Gene

GeneCards Summary for BCAP29 Gene

BCAP29 (B-Cell Receptor-Associated Protein 29) is a Protein Coding gene. An important paralog of this gene is BCAP31.

UniProtKB/Swiss-Prot for BCAP29 Gene

  • May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity).

Gene Wiki entry for BCAP29 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BCAP29 Gene

Genomics for BCAP29 Gene

Regulatory Elements for BCAP29 Gene

Genomic Location for BCAP29 Gene

107,579,977 bp from pter
107,629,170 bp from pter
49,194 bases
Plus strand

Genomic View for BCAP29 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for BCAP29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BCAP29 Gene

Proteins for BCAP29 Gene

  • Protein details for BCAP29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    B-cell receptor-associated protein 29
    Protein Accession:
    Secondary Accessions:
    • G5E9L4
    • O95003

    Protein attributes for BCAP29 Gene

    241 amino acids
    Molecular mass:
    28320 Da
    Quaternary structure:
    • Homodimer (PubMed:25327138). Heterodimer with BCAP31. Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II (By similarity).

    Three dimensional structures from OCA and Proteopedia for BCAP29 Gene

    Alternative splice isoforms for BCAP29 Gene


neXtProt entry for BCAP29 Gene

Proteomics data for BCAP29 Gene at MOPED

Post-translational modifications for BCAP29 Gene

  • Ubiquitination at Lys96, Lys157, and Lys209
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for BCAP29 Gene

Domains for BCAP29 Gene

Protein Domains for BCAP29 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q9UHQ4
  • Belongs to the BCAP29/BCAP31 family.
genes like me logo Genes that share domains with BCAP29: view

No data available for Gene Families for BCAP29 Gene

Function for BCAP29 Gene

Molecular function for BCAP29 Gene

UniProtKB/Swiss-Prot Function: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity).

Phenotypes for BCAP29 Gene

GenomeRNAi human phenotypes for BCAP29:
genes like me logo Genes that share phenotypes with BCAP29: view

miRNA for BCAP29 Gene

miRTarBase miRNAs that target BCAP29

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for BCAP29 Gene

Localization for BCAP29 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BCAP29 Gene

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for BCAP29 Gene COMPARTMENTS Subcellular localization image for BCAP29 gene
Compartment Confidence
endoplasmic reticulum 5
plasma membrane 1

Gene Ontology (GO) - Cellular Components for BCAP29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum --
GO:0005789 endoplasmic reticulum membrane IEA --
GO:0016020 membrane IDA 16210410
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with BCAP29: view

Pathways for BCAP29 Gene

SuperPathways for BCAP29 Gene

No Data Available

Gene Ontology (GO) - Biological Process for BCAP29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001649 osteoblast differentiation IDA 16210410
GO:0006886 intracellular protein transport IEA --
GO:0006888 ER to Golgi vesicle-mediated transport IEA --
GO:0006915 apoptotic process IEA --
GO:0070973 protein localization to endoplasmic reticulum exit site IEA --
genes like me logo Genes that share ontologies with BCAP29: view

No data available for Pathways by source for BCAP29 Gene

Transcripts for BCAP29 Gene

Unigene Clusters for BCAP29 Gene

B-cell receptor-associated protein 29:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for BCAP29 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11
SP1: - -
SP2: - - - - -
SP3: -
SP4: -
SP6: -

Relevant External Links for BCAP29 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BCAP29 Gene

mRNA expression in normal human tissues for BCAP29 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for BCAP29 Gene

SOURCE GeneReport for Unigene cluster for BCAP29 Gene Hs.303787

genes like me logo Genes that share expressions with BCAP29: view

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BCAP29 Gene

Orthologs for BCAP29 Gene

This gene was present in the common ancestor of animals.

Orthologs for BCAP29 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia BCAP29 35
  • 99.45 (n)
  • 99.59 (a)
BCAP29 36
  • 99 (a)
(Bos Taurus)
Mammalia BCAP29 35
  • 88.1 (n)
  • 87.82 (a)
BCAP29 36
  • 86 (a)
(Canis familiaris)
Mammalia BCAP29 35
  • 88.24 (n)
  • 87.97 (a)
BCAP29 36
  • 88 (a)
(Mus musculus)
Mammalia Bcap29 35
  • 82.92 (n)
  • 82.5 (a)
Bcap29 16
Bcap29 36
  • 81 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 37 (a)
(Ornithorhynchus anatinus)
Mammalia BCAP29 36
  • 65 (a)
(Rattus norvegicus)
Mammalia Bcap29 35
  • 83.54 (n)
  • 81.74 (a)
(Gallus gallus)
Aves BCAP29 35
  • 63.49 (n)
  • 57.58 (a)
BCAP29 36
  • 55 (a)
(Anolis carolinensis)
Reptilia BCAP29 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia bcap29 35
  • 65.42 (n)
  • 55.83 (a)
(Danio rerio)
Actinopterygii bcap29 35
  • 57 (n)
  • 53.78 (a)
bcap29 36
  • 52 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13887 36
  • 35 (a)
(Caenorhabditis elegans)
Secernentea Y54G2A.18 36
  • 38 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.13833 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10894 36
  • 37 (a)
Species with no ortholog for BCAP29:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for BCAP29 Gene

Gene Tree for BCAP29 (if available)
Gene Tree for BCAP29 (if available)

Paralogs for BCAP29 Gene

Paralogs for BCAP29 Gene

genes like me logo Genes that share paralogs with BCAP29: view

Variants for BCAP29 Gene

Sequence variations from dbSNP and Humsavar for BCAP29 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs2518 -- 107,621,830(-) gaggc(C/T)aggaa utr-variant-3-prime, nc-transcript-variant
rs2807 -- 107,620,333(-) ACAGC(C/T)GGCTA utr-variant-3-prime, nc-transcript-variant
rs2808 -- 107,620,411(-) GAGAG(C/T)ACTAG utr-variant-3-prime, nc-transcript-variant
rs740085 -- 107,592,450(-) tccat(A/G)tcctc intron-variant
rs2057837 -- 107,582,280(+) ATCCT(C/G)ATCAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BCAP29 Gene

Variant ID Type Subtype PubMed ID
nsv888940 CNV Loss 21882294
esv1284866 CNV Insertion 17803354
nsv366928 CNV Loss 16902084

Relevant External Links for BCAP29 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BCAP29 Gene

Disorders for BCAP29 Gene

Relevant External Links for BCAP29

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with BCAP29: view

No data available for UniProtKB/Swiss-Prot for BCAP29 Gene

Publications for BCAP29 Gene

  1. Two new proteins preferentially associated with membrane immunoglobulin D. (PMID: 8070407) Kim K.M. … Reth M. (EMBO J. 1994) 2 3
  2. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PMID: 10931946) Hu R.-M. … Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 4
  3. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4
  4. A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum. (PMID: 12886015) Schamel W.W. … Reth M. (Proc. Natl. Acad. Sci. U.S.A. 2003) 2 3
  5. An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PMID: 20677014) Shimada M. … Tokunaga K. (Hum. Genet. 2010) 3 48

Products for BCAP29 Gene

Sources for BCAP29 Gene

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