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Aliases for BCAP29 Gene

Aliases for BCAP29 Gene

  • B-Cell Receptor-Associated Protein 29 2 3 5
  • BCR-Associated Protein 29 3 4
  • BAP29 3 4

External Ids for BCAP29 Gene

Previous GeneCards Identifiers for BCAP29 Gene

  • GC07P106781
  • GC07P106814
  • GC07P107007
  • GC07P107220
  • GC07P101581

Summaries for BCAP29 Gene

GeneCards Summary for BCAP29 Gene

BCAP29 (B-Cell Receptor-Associated Protein 29) is a Protein Coding gene. An important paralog of this gene is BCAP31.

UniProtKB/Swiss-Prot for BCAP29 Gene

  • May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity).

Gene Wiki entry for BCAP29 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BCAP29 Gene

Genomics for BCAP29 Gene

Regulatory Elements for BCAP29 Gene

Enhancers for BCAP29 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around BCAP29 on UCSC Golden Path with GeneCards custom track

Promoters for BCAP29 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around BCAP29 on UCSC Golden Path with GeneCards custom track

Genomic Location for BCAP29 Gene

107,579,977 bp from pter
107,629,170 bp from pter
49,194 bases
Plus strand

Genomic View for BCAP29 Gene

Genes around BCAP29 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BCAP29 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BCAP29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BCAP29 Gene

Proteins for BCAP29 Gene

  • Protein details for BCAP29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    B-cell receptor-associated protein 29
    Protein Accession:
    Secondary Accessions:
    • G5E9L4
    • O95003

    Protein attributes for BCAP29 Gene

    241 amino acids
    Molecular mass:
    28320 Da
    Quaternary structure:
    • Homodimer (PubMed:25327138). Heterodimer with BCAP31. Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II (By similarity).

    Three dimensional structures from OCA and Proteopedia for BCAP29 Gene

    Alternative splice isoforms for BCAP29 Gene


neXtProt entry for BCAP29 Gene

Proteomics data for BCAP29 Gene at MOPED

Post-translational modifications for BCAP29 Gene

  • Ubiquitination at Lys 96, Lys 157, and Lys 209
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Abcam antibodies for BAP29

No data available for DME Specific Peptides for BCAP29 Gene

Domains & Families for BCAP29 Gene

Protein Domains for BCAP29 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the BCAP29/BCAP31 family.
  • Belongs to the BCAP29/BCAP31 family.
genes like me logo Genes that share domains with BCAP29: view

No data available for Gene Families for BCAP29 Gene

Function for BCAP29 Gene

Molecular function for BCAP29 Gene

UniProtKB/Swiss-Prot Function:
May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity).
genes like me logo Genes that share phenotypes with BCAP29: view

Animal Model Products

CRISPR Products

miRNA for BCAP29 Gene

miRTarBase miRNAs that target BCAP29

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BCAP29 Gene

Localization for BCAP29 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BCAP29 Gene

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for BCAP29 Gene COMPARTMENTS Subcellular localization image for BCAP29 gene
Compartment Confidence
endoplasmic reticulum 5
cytosol 2
plasma membrane 1

Gene Ontology (GO) - Cellular Components for BCAP29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005789 endoplasmic reticulum membrane IEA --
genes like me logo Genes that share ontologies with BCAP29: view

Pathways & Interactions for BCAP29 Gene

SuperPathways for BCAP29 Gene

No Data Available

Gene Ontology (GO) - Biological Process for BCAP29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006886 intracellular protein transport IEA --
genes like me logo Genes that share ontologies with BCAP29: view

No data available for Pathways by source and SIGNOR curated interactions for BCAP29 Gene

Drugs & Compounds for BCAP29 Gene

No Compound Related Data Available

Transcripts for BCAP29 Gene

Unigene Clusters for BCAP29 Gene

B-cell receptor-associated protein 29:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for BCAP29 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11
SP1: - -
SP2: - - - - -
SP3: -
SP4: -
SP6: -

Relevant External Links for BCAP29 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BCAP29 Gene

mRNA expression in normal human tissues for BCAP29 Gene

Protein differential expression in normal tissues from HIPED for BCAP29 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (12.2) and Frontal cortex (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for BCAP29 Gene

SOURCE GeneReport for Unigene cluster for BCAP29 Gene Hs.303787

genes like me logo Genes that share expression patterns with BCAP29: view

Protein tissue co-expression partners for BCAP29 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for BCAP29 Gene

Orthologs for BCAP29 Gene

This gene was present in the common ancestor of animals.

Orthologs for BCAP29 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia BCAP29 35
  • 88.1 (n)
  • 87.82 (a)
BCAP29 36
  • 86 (a)
(Canis familiaris)
Mammalia BCAP29 35
  • 88.24 (n)
  • 87.97 (a)
BCAP29 36
  • 88 (a)
(Mus musculus)
Mammalia Bcap29 35
  • 82.92 (n)
  • 82.5 (a)
Bcap29 16
Bcap29 36
  • 81 (a)
(Pan troglodytes)
Mammalia BCAP29 35
  • 99.45 (n)
  • 99.59 (a)
BCAP29 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Bcap29 35
  • 83.54 (n)
  • 81.74 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 37 (a)
(Ornithorhynchus anatinus)
Mammalia BCAP29 36
  • 65 (a)
(Gallus gallus)
Aves BCAP29 35
  • 63.49 (n)
  • 57.58 (a)
BCAP29 36
  • 55 (a)
(Anolis carolinensis)
Reptilia BCAP29 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia bcap29 35
  • 65.42 (n)
  • 55.83 (a)
(Danio rerio)
Actinopterygii bcap29 35
  • 57 (n)
  • 53.78 (a)
bcap29 36
  • 52 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13887 36
  • 35 (a)
(Caenorhabditis elegans)
Secernentea Y54G2A.18 36
  • 38 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.13833 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10894 36
  • 37 (a)
Species with no ortholog for BCAP29:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for BCAP29 Gene

Gene Tree for BCAP29 (if available)
Gene Tree for BCAP29 (if available)

Paralogs for BCAP29 Gene

Paralogs for BCAP29 Gene

genes like me logo Genes that share paralogs with BCAP29: view

Variants for BCAP29 Gene

Sequence variations from dbSNP and Humsavar for BCAP29 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs6958094 -- 107,618,462(+) ACCGG(C/T)TCGTA intron-variant, nc-transcript-variant, reference, missense, utr-variant-3-prime
rs6960817 -- 107,609,944(+) TGCCA(A/G)TGCCT intron-variant
rs6971658 -- 107,612,433(+) tatat(A/T)tatat intron-variant
rs13224903 -- 107,594,588(+) gctcc(A/G)cctcc intron-variant
rs13230654 -- 107,597,659(+) aaagg(G/T)taagt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BCAP29 Gene

Variant ID Type Subtype PubMed ID
nsv888940 CNV Loss 21882294
esv1284866 CNV Insertion 17803354
nsv366928 CNV Loss 16902084

Variation tolerance for BCAP29 Gene

Residual Variation Intolerance Score: 44.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.86; 58.88% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for BCAP29 Gene

Disorders for BCAP29 Gene

Relevant External Links for BCAP29

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for BCAP29 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BCAP29 Gene

Publications for BCAP29 Gene

  1. A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. (PMID: 21378988) (Nat. Genet. 2011) 3 48 67
  2. A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum. (PMID: 12886015) Schamel W.W. … Reth M. (Proc. Natl. Acad. Sci. U.S.A. 2003) 2 3
  3. Two new proteins preferentially associated with membrane immunoglobulin D. (PMID: 8070407) Kim K.M. … Reth M. (EMBO J. 1994) 2 3
  4. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3

Products for BCAP29 Gene

Sources for BCAP29 Gene