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Aliases for BCAP29 Gene

Aliases for BCAP29 Gene

  • B-Cell Receptor Associated Protein 29 2 3 5
  • B-Cell Receptor-Associated Protein 29 2 3
  • BCR-Associated Protein 29 3 4
  • BAP29 3 4

External Ids for BCAP29 Gene

Previous GeneCards Identifiers for BCAP29 Gene

  • GC07P106781
  • GC07P106814
  • GC07P107007
  • GC07P107220
  • GC07P101581

Summaries for BCAP29 Gene

GeneCards Summary for BCAP29 Gene

BCAP29 (B-Cell Receptor Associated Protein 29) is a Protein Coding gene. Among its related pathways are B Cell Receptor Signaling Pathway (sino) and AKT Signaling Pathway. An important paralog of this gene is BCAP31.

UniProtKB/Swiss-Prot for BCAP29 Gene

  • May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity).

Gene Wiki entry for BCAP29 Gene

Additional gene information for BCAP29 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BCAP29 Gene

Genomics for BCAP29 Gene

Regulatory Elements for BCAP29 Gene

Enhancers for BCAP29 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H107178 1.4 Ensembl ENCODE dbSUPER 4.4 -399.8 -399775 2.5 PKNOX1 NFIB INSM2 FEZF1 RFX5 ZNF121 EGR1 ZNF366 FOS DEK COG5 BCAP29 ENSG00000272072 HBP1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around BCAP29 on UCSC Golden Path with GeneCards custom track

Promoters for BCAP29 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000216584 424 2400 ARNT SIN3A DMAP1 ZNF2 ZBTB7B YY1 ZNF143 ZNF207 SP3 ZHX2

Genomic Locations for BCAP29 Gene

Genomic Locations for BCAP29 Gene
49,194 bases
Plus strand

Genomic View for BCAP29 Gene

Genes around BCAP29 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BCAP29 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BCAP29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BCAP29 Gene

Proteins for BCAP29 Gene

  • Protein details for BCAP29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    B-cell receptor-associated protein 29
    Protein Accession:
    Secondary Accessions:
    • G5E9L4
    • O95003

    Protein attributes for BCAP29 Gene

    241 amino acids
    Molecular mass:
    28320 Da
    Quaternary structure:
    • Homodimer (PubMed:25327138). Heterodimer with BCAP31. Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II (By similarity).

    Three dimensional structures from OCA and Proteopedia for BCAP29 Gene

    Alternative splice isoforms for BCAP29 Gene


neXtProt entry for BCAP29 Gene

Post-translational modifications for BCAP29 Gene

  • Ubiquitination at posLast=9696, posLast=157157, and Lys209
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for BCAP29 Gene

Domains & Families for BCAP29 Gene

Gene Families for BCAP29 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Predicted secreted proteins
  • Transporters

Protein Domains for BCAP29 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the BCAP29/BCAP31 family.
  • Belongs to the BCAP29/BCAP31 family.
genes like me logo Genes that share domains with BCAP29: view

Function for BCAP29 Gene

Molecular function for BCAP29 Gene

UniProtKB/Swiss-Prot Function:
May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity).

Phenotypes From GWAS Catalog for BCAP29 Gene

genes like me logo Genes that share phenotypes with BCAP29: view

Animal Model Products

miRNA for BCAP29 Gene

miRTarBase miRNAs that target BCAP29

Clone Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BCAP29 Gene

Localization for BCAP29 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BCAP29 Gene

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for BCAP29 gene
Compartment Confidence
endoplasmic reticulum 5
cytosol 2
plasma membrane 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for BCAP29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IEA --
GO:0005789 endoplasmic reticulum membrane IBA --
GO:0016020 membrane IDA,IEA 16210410
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with BCAP29: view

Pathways & Interactions for BCAP29 Gene

genes like me logo Genes that share pathways with BCAP29: view

Pathways by source for BCAP29 Gene

2 Sino Biological pathways for BCAP29 Gene

Gene Ontology (GO) - Biological Process for BCAP29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001649 osteoblast differentiation IDA 16210410
GO:0006810 transport IEA --
GO:0006886 intracellular protein transport IEA --
GO:0006888 ER to Golgi vesicle-mediated transport IBA,IEA --
GO:0006915 apoptotic process IEA --
genes like me logo Genes that share ontologies with BCAP29: view

No data available for SIGNOR curated interactions for BCAP29 Gene

Drugs & Compounds for BCAP29 Gene

No Compound Related Data Available

Transcripts for BCAP29 Gene

Unigene Clusters for BCAP29 Gene

B-cell receptor-associated protein 29:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for BCAP29 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11
SP1: - -
SP2: - - - - -
SP3: -
SP4: -
SP6: -

Relevant External Links for BCAP29 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BCAP29 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BCAP29 Gene

Protein differential expression in normal tissues from HIPED for BCAP29 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (12.2) and Frontal cortex (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for BCAP29 Gene

Protein tissue co-expression partners for BCAP29 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of BCAP29 Gene:


SOURCE GeneReport for Unigene cluster for BCAP29 Gene:


Evidence on tissue expression from TISSUES for BCAP29 Gene

  • Nervous system(4.5)
  • Adrenal gland(4.3)
  • Lung(2.2)
genes like me logo Genes that share expression patterns with BCAP29: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for BCAP29 Gene

Orthologs for BCAP29 Gene

This gene was present in the common ancestor of animals.

Orthologs for BCAP29 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia BCAP29 33 34
  • 99.45 (n)
(Canis familiaris)
Mammalia BCAP29 33 34
  • 88.24 (n)
(Bos Taurus)
Mammalia BCAP29 33 34
  • 88.1 (n)
(Rattus norvegicus)
Mammalia Bcap29 33
  • 83.54 (n)
(Mus musculus)
Mammalia Bcap29 33 16 34
  • 82.92 (n)
(Ornithorhynchus anatinus)
Mammalia BCAP29 34
  • 65 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 37 (a)
(Gallus gallus)
Aves BCAP29 33 34
  • 63.49 (n)
(Anolis carolinensis)
Reptilia BCAP29 34
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia bcap29 33
  • 65.42 (n)
(Danio rerio)
Actinopterygii bcap29 33 34
  • 57 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG13887 34
  • 35 (a)
(Caenorhabditis elegans)
Secernentea Y54G2A.18 34
  • 38 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10894 34
  • 37 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.13833 33
Species where no ortholog for BCAP29 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for BCAP29 Gene

Gene Tree for BCAP29 (if available)
Gene Tree for BCAP29 (if available)

Paralogs for BCAP29 Gene

Paralogs for BCAP29 Gene

genes like me logo Genes that share paralogs with BCAP29: view

Variants for BCAP29 Gene

Sequence variations from dbSNP and Humsavar for BCAP29 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000136549 -- 107,583,401(+) TTCCC(C/T)CATGG intron-variant
rs1000219322 -- 107,591,897(+) AGAAA(C/T)TGGAC intron-variant
rs1000241756 -- 107,611,299(+) CAGTG(A/G)CTCAC intron-variant
rs1000297434 -- 107,583,157(+) ATTGC(A/G)TGATG intron-variant
rs1000380425 -- 107,597,351(+) GATTA(C/T)AGGCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BCAP29 Gene

Variant ID Type Subtype PubMed ID
nsv608074 CNV loss 21841781
nsv366928 CNV deletion 16902084
esv3614462 CNV gain 21293372
esv3572051 CNV loss 25503493
esv1284866 CNV insertion 17803354

Variation tolerance for BCAP29 Gene

Residual Variation Intolerance Score: 44.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.86; 58.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for BCAP29 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BCAP29 Gene

Disorders for BCAP29 Gene

Relevant External Links for BCAP29

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for BCAP29 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BCAP29 Gene

Publications for BCAP29 Gene

  1. Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. (PMID: 21068099) Evangelou E … Translation Research in Europe Applied Technologies for Osteoarthritis (TreatOA) (Annals of the rheumatic diseases 2011) 3 45 60
  2. A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. (PMID: 21378988) Coronary Artery Disease (C4D) Genetics Consortium (Nature genetics 2011) 3 45 60
  3. An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PMID: 20677014) Shimada M … Tokunaga K (Human genetics 2010) 3 45 60
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  5. A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum. (PMID: 12886015) Schamel WW … Reth M (Proceedings of the National Academy of Sciences of the United States of America 2003) 2 3 60

Products for BCAP29 Gene

Sources for BCAP29 Gene

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