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BCAN Gene

protein-coding GIFtS: 57

GC01P154878

brevican
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
BEHAB ^¹, ², ³
CSPG7 ^¹, ², ³
MGC13038 ^¹, ²
OTTHUMP00000032164 ^²
OTTHUMP00000032165 ^²
brevican ^²

Descriptions
Brain-enriched hyaluronan-binding protein ^³
Protein BEHAB ^³
brevican proteoglycan ^²
chondroitin sulfate proteoglycan 7 ^²
chondroitin sulfate proteoglycan BEHAB ^²
chondroitin sulfate proteoglycan BEHAB/brevican ^²

External Ids
HGNC: 23059¹
Entrez Gene: 63827²
UniProtKB: Q96GW7³
Ensembl: ENSG00000132692⁷

Search outside databases for aliases for BCAN gene

Previous GC identifers: GC01P154481 GC01P152377 GC01P153390 GC01P153828 GC01P153424

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: PGCB_HUMAN, Q96GW7

Function: May play a role in the terminally differentiating and the adult nervous system during

postnatal development. Could stabilize interactions between hyaluronan (HA) and brain

proteoglycans

Gene Wiki entry for BCAN (Brevican)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the BCAN gene

Entrez Gene cytogenetic band: 1q31 Ensembl cytogenetic band: 1q23.1 HGNC cytogenetic band: 1q31

BCAN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P154878: (about GC identifiers)

Start:	154,878,357 bp from pter
End:	154,895,944 bp from pter
Size:	17,588 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000001.9 NT_004487.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: PGCB_HUMAN, Q96GW7 (See protein sequence)

Recommended Name: Brevican core protein precursor

Size: 911 amino acids; 99118 Da

Subunit: Interacts with TNR (By similarity)

Subcellular location: Isoform 1: Secreted, extracellular space, extracellular matrix

Subcellular location: Isoform 2: Membrane; Lipid-anchor, GPI-anchor

Developmental stage: Isoform 1 is highly expressed from birth through 8 years of age and is

down-regulated by 20 years of age to low levels that are maintained in the normal adult cortex.

Isoform 2 is expressed at uniformly low levels throughout development

Secondary accessions: Q8TBB9 Q9HBK1 Q9HBK4

Alternative splicing: 2 isoforms: Q96GW7-1 Q96GW7-2

Post-translational modifications:

Contains mostly chondroitin sulfate (By similarity)¹

Isoform 2 is predicted to have its GPI-anchor on 'Asn-649'¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_068767.3 NP_940819.1

ENSEMBL proteins:

ENSP00000331210 ENSP00000354925 ENSP00000255029

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	R&D Systems Recombinant & Natural Proteins for BCAN (Brevican)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Brevican)
	Human Recombinant Proteins from Abnova (BCAN)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5/8 Gene Ontology (GO) cellular component terms (links to tree view) (see all 8 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005578	proteinaceous extracellular matrix	IEA	--
GO:0005634	nucleus	IDA	18029348
GO:0005730	NOT nucleolus	IDA	18029348
GO:0005737	cytoplasm	IDA	18029348

About this table

Antibodies for BCAN:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for BCAN
	R&D Systems Antibodies for BCAN (Brevican)
	Antibodies from Abcam (Brevican), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (BCAN)
	Novus Biologicals Antibodies for BCAN

Assays for BCAN:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q96GW7

ProtoNet protein and cluster: Q96GW7

4 Blocks protein families:

IPB000436 Sushi domain/SCR domain/CCP module

IPB000538 Link domain

IPB002353 Type II antifreeze protein signature

IPB013106 Immunoglobulin V-set

UniProtKB/Swiss-Prot: PGCB_HUMAN, Q96GW7

Similarity: Belongs to the aggrecan/versican proteoglycan family

Similarity: Contains 1 C-type lectin domain

Similarity: Contains 1 EGF-like domain

Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain

Similarity: Contains 2 Link domains

Similarity: Contains 1 Sushi (CCP/SCR) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (BCAN)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_198427

Applied Biosystems Silencer® siRNAs for BCAN

Sigma-Aldrich siRNA and siRNA Panels for BCAN

Sigma-Aldrich shRNA Panels and shRNA for BCAN

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for BCAN
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_021948
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_021948
untagged cDNA clones in CMV expression vector (see all 4): BC010117

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_021948

UniProtKB/Swiss-Prot: PGCB_HUMAN, Q96GW7

Function: May play a role in the terminally differentiating and the adult nervous system during

postnatal development. Could stabilize interactions between hyaluronan (HA) and brain

proteoglycans

2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Bcan):

behavior/neurological

nervous system

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005488	binding	IEA	--
GO:0005529	sugar binding	IEA	--
GO:0005540	hyaluronic acid binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for BCAN

5/11 Interacting proteins for BCAN (Q96GW7² ENSP00000331210³) via UniProtKB, MINT, and/or STRING (see all 11 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TNR	ENSP00000263525³	STRING (score=.986)
DCN	ENSP00000052754³	STRING (score=.919)
ADAMTS4	ENSP00000356975³	STRING (score=.901)
FBLN2	ENSP00000295761³	STRING (score=.869)
FN1	ENSP00000323534³	STRING (score=.854)

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007155	cell adhesion	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for BCAN

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (BCAN)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_198427

Sigma-Aldrich siRNA and siRNA Panels for BCAN

Sigma-Aldrich shRNA Panels and shRNA for BCAN

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_021948 NM_198427

REFSEQ mRNAs for BCAN gene (2 alternative transcripts):

NM_021948.3 NM_198427.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_021948 NM_198427

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_021948
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_021948
                                 untagged cDNA clones in CMV expression vector (see all 4): BC010117

Additional cDNA sequence:

BC010117.2 BC067354.1

24/25 DOTS entries (see all 25 ):

DT.110521 DT.101984636 DT.75102201 DT.86846012 DT.121406541 DT.101984634 DT.100806730 DT.436076

DT.95254987 DT.91944937 DT.121406534 DT.92457078 DT.92457091 DT.91705336 DT.92457086 DT.92457087

DT.95088684 DT.100030847 DT.100806732 DT.75186146 DT.92457081 DT.95088681 DT.95142948 DT.95209711

24/394 AceView cDNA sequences (see all 394 ):

CD673033 BC029348 BF347021 BF527186 BG818851 AW291404 CB153236 BF338679

BG910211 AI880291 BC035457 BF527689 BC023209 CB153420 BG914019 BC027971

BF345818 BC009117 BF530989 BM708927 AL538295 BF526392 BG818856 AF268002

highest scoring ESTs for BCAN:

AI979110 AA758271 AF228710 AI205180 AI272375 AI337268 AI343343 AI361061 AI378579 AI880216

Unigene Clusters for BCAN:

Brevican

Hs.516904 [show with all ESTs], Hs.663621 [show with all ESTs]

Unigene Representative Sequences: NM_021948, BC010117

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for BCAN (see all 12 )

ExUns:	1	^	2a	·	2b	^	3	^	4a	·	4b	·	4c	·	4d	^	5	^	6	^	7a	·	7b	^	8	^	9	^	10a	·	10b	^	11	^	12a	·	12b	^	13a	·	13b	^	14a	·	14b	^	15	^	16	^	17	^
SP1:															-		-		-
SP2:																	-
SP3:																																											-
SP4:									-								-
SP5:																	-

ExUns:	18a	·	18b
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for BCAN

3 Ensembl transcripts including schematic representations:

ENST00000329117 ENST00000361588 ENST00000255029

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

BCAN expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for BCAN

¹ / ² / ³

17 probe-sets matching BCAN gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
80560_at²^{, 3}	U95-E	1	1.00	1.00	0.91	0.92	AI423098	0.60	1.00	0.82	1
91920_at²^{, 3}	U133-E	1	1.00	1.00	0.87	1.61	AI205180	0.80	1.00	0.91	1
81773_r_at²^{, 3}	U95-D	1	1.00	1.00	0.43	0.68	AI343343	0.80	1.00	0.91	1
60064_g_at²^{, 3}	U95-C	1	1.00	1.00	0.89	0.95	AI979110	1.00	1.00	1.00	1
92116_at²^{, 3}	U95-D	1	1.00	1.00	0.91	1.19	AA758271	0.80	1.00	0.91	1
83852_at²^{, 3}	U95-E	1	0.94	1.00	-0.18	0.68	AI337268	0.80	1.00	0.91	1
60063_at²^{, 3}	U95-C	1	0.69	1.00	0.69	1.06	AI979110	1.00	1.00	1.00	1
219107_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_021948	0.60	1.00	0.82	1
223632_s_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AI739071	0.60	1.00	0.82	1
221623_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AF229053	0.60	1.00	0.82	1
223633_s_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BC005081	0.40	1.00	0.76	1
91920_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI205180	0.80	1.00	0.91	1
219107_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
223632_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
221623_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
223633_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
91920_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks BCAN for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TAGATCAGAG

SOURCE GeneReport for Unigene clusters: Hs.516904 Hs.663621

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for BCAN gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	BCAN¹	--	brevican	88.06(n) 88.42(a)	612102 XM_849830.1 XP_854923.1
chimpanzee (Pan troglodytes)	BCAN¹	--	brevican	99.49(n) 99.67(a)	457401 XM_001166271.1 XP_001166271.1
cow (Bos taurus)	BCAN¹	--	brevican	89.16(n) 89.67(a)	281019 NM_173996.2 NP_776421.1
rat (Rattus norvegicus)	Bcan¹	--	brevican	83.26(n) 84.97(a)	25393 NM_001033665.1 NP_001028837.1
mouse (Mus musculus)	Bcan^{1, 5}	3 (42.70 cM)⁵	brevican^{1, 5}	82.99(n)¹ 83.83(a)¹	12032¹ NM_007529.1¹ NP_031555.1¹ AK144405⁵ AK161874⁵ (see all 10)

About this table Species with no ortholog for BCAN

ENSEMBL Gene Tree for BCAN

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for BCAN gene

ACAN² VCAN²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/111 NCBI SNPs in BCAN are shown (see all 111 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 67)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1361745^1,2	A,C,F,H,O	154877274(-)	`TCACAA/TAAAAA`	2	--	ng5¹		7		EU EA WA NA	558
	rs1361744^1,2	A,C,F,H	154877312(-)	`CAGTGT/CCATGG`	2	--	ng5¹		7		EU EA WA	716
	rs1056695^1,2	A,C,F,H	154888876(+)	`AGGAGG/AAGTCA`	2	K/E	mis¹		9		EA EU WA NA	2278
	rs11360^1,2	A,C,F,H	154895661(+)	`GTGGTG/ACTGGA`	1	--	ut3¹ ese³		11		MN EA NA EU WA	2636
	rs2236601^1,2	C,F,H	154896061(-)	`ATCTTG/AGGGAC`	1	--	ng3¹		20		EA NA EU WA	3246
	rs12065791^1,2	C,F,H	154887875(+)	`AGACTC/TGGCCC`	2	S/L	mis¹ ese³		8		EU EA WA	800
	rs7529735^1,2	F,H	154876385(+)	`CAAGAA/GCTGTG`	2	--	ng5¹		4		EU EA WA	382
	rs3795735^1,2	F,H	154878008(+)	`CACAGG/AAGCCA`	2	--	ng5¹		3		EU EA	270
	rs2365713^1,2	A,C	154877502(-)	`GATCCC/TCATAA`	2	--	ng5¹		0	--	--	--	--
	rs10908513^1,2	A	154890249(+)	`CAGCCC/TGGAGT`	2	--	int¹ ng3¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for BCAN (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 600347

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/19 PubMed articles for BCAN gene (see all 19 ):

cDNA cloning, chromosomal localization, and expression analysis of human BEHAB/brevican, a brain specific proteoglycan regulated during cortical development and in glioma. (PubMed id 11054543)^{2, 3, 4} Gary S.C.... Hockfield S. (2000)
Human BRAL1 and BCAN genes that belong to the link-module superfamily are tandemly arranged on chromosome 1q21-23. (PubMed id 11873941)^{1, 2, 3} Nomoto H....Ninomiya Y. (2002)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{3, 4} Clark H.F....Gray A. (2003)
The proteoglycan brevican binds to fibronectin after proteolytic cleavage and promotes glioma cell motility. (PubMed id 18611854)³ Hu B....Viapiano M.S. (2008)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)³ Barbe L....Andersson-Svahn H. (2008)
Novel tumor-specific isoforms of BEHAB/brevican identified in human malignant gliomas. (PubMed id 16061654)³ Viapiano M.S....Matthews R.T. (2005)
Human glioblastomas overexpress ADAMTS-5 that degrades brevican. (PubMed id 16133547)³ Nakada M....Okada Y. (2005)
Secreted brevican mRNA is expressed in the adult rat pituitary. (PubMed id 14741698)³ Dong Y....Lu Y. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)³ Ota T....Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 63827	HGNC: 23059	AceView: BCAN	Ensembl:ENSG00000132692	euGenes: HUgn63827
ECgene: BCAN	H-InvDB: BCAN

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
Functional Glycomics Gateway - Glycan Binding	http://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Ctlect_212

Licensable Technologies for BCAN
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for BCAN:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for BCAN-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for BCAN		Antibodies for BCAN
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for BCAN		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (BCAN)
	Antibodies (BCAN)
	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Brevican)
	Antibodies (Brevican)

Search OriGene for BCAN

Search Tocris compounds for BCAN

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for BCAN

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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BCAN Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for BCAN

Summaries
for BCAN

Genomic Location
for BCAN

Proteins
for BCAN

Protein Domains/
Families
for BCAN

Gene Function
for BCAN

Pathways & Interactions
for BCAN

Drugs & Compounds
for BCAN

Transcripts
for BCAN

Expression
for BCAN

Orthologs
for BCAN

Paralogs
for BCAN

SNPs/Variants
for BCAN

Disorders & Mutations
for BCAN

Medical News
for BCAN

Publications
for BCAN

Search for BCAN

Genome Databases showing BCAN

Other Databases showing BCAN

Specialized Databases showing BCAN

Licensable Technologies
for BCAN

Services
for BCAN

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

BCAN Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor BCAN

Summariesfor BCAN

Genomic Locationfor BCAN

Proteinsfor BCAN

Protein Domains/Familiesfor BCAN

Gene Functionfor BCAN

Pathways & Interactionsfor BCAN

Drugs & Compoundsfor BCAN

Transcriptsfor BCAN

Expression for BCAN

Orthologsfor BCAN

Paralogsfor BCAN

SNPs/Variantsfor BCAN

Disorders & Mutationsfor BCAN

Medical Newsfor BCAN

Publicationsfor BCAN

Search for BCAN

Genome Databases showing BCAN

Other Databases showing BCAN

Specialized Databases showing BCAN

Licensable Technologiesfor BCAN

Servicesfor BCAN

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for BCAN

Summaries
for BCAN

Genomic Location
for BCAN

Proteins
for BCAN

Protein Domains/
Families
for BCAN

Gene Function
for BCAN

Pathways & Interactions
for BCAN

Drugs & Compounds
for BCAN

Transcripts
for BCAN

Expression
for BCAN

Orthologs
for BCAN

Paralogs
for BCAN

SNPs/Variants
for BCAN

Disorders & Mutations
for BCAN

Medical News
for BCAN

Publications
for BCAN

Licensable Technologies
for BCAN

Services
for BCAN