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BCAM Gene

protein-coding GIFtS: 60

GC19P050005

basal cell adhesion molecule (Lutheran blood group)
(Previous names: Lutheran blood group (Auberger b antigen included), basal cell adhesion molecule (Lu and Au blood groups) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: LU)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
AU ^², ⁵
CD239 ^¹, ²
LU ^², ³, ⁵
MSK19 ^², ³

Descriptions
Auberger B antigen ^², ³
B-CAM cell surface glycoprotein ^², ³
B-cell adhesion molecule ^²
CD239 antigen ^³
F8/G253 antigen ^², ³
Lutheran blood group (Auberger b antigen included) ^¹, ²
antigen identified by monoclonal antibody F8 ^²
basal cell adhesion molecule ^²
basal cell adhesion molecule (Lu and Au blood groups) ^¹, ²
basal cell adhesion molecule (Lutheran blood group) ^²
glycoprotein 95kDa ^²

External Ids
HGNC: 6722¹
Entrez Gene: 4059²
UniProtKB: P50895³
Ensembl: ENSG00000187244⁷

Search outside databases for aliases for BCAM gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for BCAM:

Lutheran blood group glycoprotein is a member of the immunoglobulin superfamily and a receptor for

the extracellular matrix protein, laminin. The protein contains five, N-terminus, extracellular

immunoglobulin domains, a single transmembrane domain, and a short, C-terminal cytoplasmic tail.

This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in

sickle cell disease. Two transcript variants encoding different isoforms have been found for this

gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: LU_HUMAN, P50895

Function: Laminin alpha-5 receptor. May mediate intracellular signaling

Gene Wiki entry for BCAM

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the BCAM gene

Entrez Gene cytogenetic band: 19q13.2 Ensembl cytogenetic band: 19q13.32 HGNC cytogenetic band: 19q12-q13

BCAM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P050005: (about GC identifiers)

Start:	50,004,178 bp from pter
End:	50,016,518 bp from pter
Size:	12,341 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000019.8 NT_011109.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: LU_HUMAN, P50895 (See protein sequence)

Recommended Name: Lutheran blood group glycoprotein precursor

Size: 628 amino acids; 67405 Da

Subcellular location: Membrane; Single-pass type I membrane protein

Developmental stage: Is under developmental control in liver and may also be regulated during

differentiation in other tissues. Up-regulated following malignant transformation in some cell

types

Sequence caution: Sequence=EAW57297.1; Type=Erroneous gene model prediction;

PDB structure from and Proteopedia :

2PET (3D)

2PF6 (3D)

Secondary accessions: A8MYF9 A9YWT5 A9YWT6 Q86VC7

Post-translational modifications:

Epinephrine-stimulated phosphorylation of Ser-621 by PKA enhances adhesion to laminin¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_001013275.1 NP_005572.2

ENSEMBL proteins:

ENSP00000270233 ENSP00000375817

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	R&D Systems Recombinant & Natural Proteins for BCAM
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (CD239)
	Human Recombinant Proteins from Abnova (BCAM)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	TAS	9166867
GO:0005887	integral to plasma membrane	TAS	7777537
GO:0009986	cell surface	IDA	12493773

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Antibodies for BCAM:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for BCAM
	R&D Systems Antibodies for BCAM
	Antibodies from Abcam (CD239), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (BCAM)
	Novus Biologicals Antibodies for BCAM

Assays for BCAM:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	R&D Systems ELISAs for BCAM (see all)
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P50895

ProtoNet protein and cluster: P50895

2 Blocks protein families:

IPB003598 Immunoglobulin C-2 type

IPB013162 CD80-like C2-set immunoglobulin

UniProtKB/Swiss-Prot: LU_HUMAN, P50895

Similarity: Contains 3 Ig-like C2-type (immunoglobulin-like) domains

Similarity: Contains 2 Ig-like V-type (immunoglobulin-like) domains

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (BCAM)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (BCAM)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_005581

Applied Biosystems Silencer® siRNAs for BCAM

Sigma-Aldrich siRNA and siRNA Panels for BCAM

Sigma-Aldrich shRNA Panels and shRNA for BCAM

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001013257
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001013257
untagged cDNA clones in CMV expression vector (see all 2): NM_001013257

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_005581

UniProtKB/Swiss-Prot: LU_HUMAN, P50895

Function: Laminin alpha-5 receptor. May mediate intracellular signaling

7 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Bcam):

digestive/alimentary	growth/size	life span-post-weaning/aging	nervous system	normal
renal/urinary system	reproductive system

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004888	transmembrane receptor activity	TAS	7777537
GO:0005515	protein binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for BCAM

5/10 Interacting proteins for BCAM (ENSP00000270233³) via UniProtKB, MINT, and/or STRING (see all 10 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
LAMA5	ENSP00000252999³	STRING (score=.988)
CAPN5	ENSP00000354087³	STRING (score=.899)
CSNK2A1P	ENSP00000371400³	STRING (score=.899)
ELK1	ENSP00000366184³	STRING (score=.899)
GALK1	ENSP00000364334³	STRING (score=.899)

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2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007155	cell adhesion	TAS	7954395
GO:0007165	signal transduction	TAS	7777537

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for BCAM

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (BCAM)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (BCAM)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_005581

Sigma-Aldrich siRNA and siRNA Panels for BCAM

Sigma-Aldrich shRNA Panels and shRNA for BCAM

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001013257 NM_005581

REFSEQ mRNAs for BCAM gene (2 alternative transcripts):

NM_001013257.1 NM_005581.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001013257 NM_005581

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001013257
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001013257
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_001013257

Additional cDNA sequence:

BC036745.1 BC050450.1 BC128254.1 CR611746.1 X80026.1 X83425.1

16 DOTS entries:

DT.450799 DT.95290922 DT.95228681 DT.100756826 DT.91907749 DT.95138373 DT.100029416 DT.97775394

DT.100758289 DT.121502442 DT.40286229 DT.40116159 DT.91760413 DT.95108934 DT.95334997 DT.99962805

24/406 AceView cDNA sequences (see all 406 ):

C05050 AA292790 BF876484 BX397124 BQ953784 BE869834 CD671111 BF724233

R47950 X83425 BM552640 BF876486 BI964174 BE712985 BI963871 BQ879357

CR611746 AI499132 AA430383 BE712993 BI759375 BE712869 AA292401 BC050450

highest scoring ESTs for BCAM:

AA236709 AA290786 AA292790 AA428332 AA430560 AA433977 AA477340 AA479554 AA479650 AA479720

Unigene Cluster for BCAM:

Basal cell adhesion molecule (Lutheran blood group)

Hs.625725 [show with all ESTs]

Unigene Representative Sequence: BC050450

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for BCAM (see all 6 )

ExUns:	1	^	2	^	3a	·	3b	^	4	^	5a	·	5b	^	6a	·	6b	^	7	^	8	^	9	^	10a	·	10b	^	11	^	12a	·	12b	^	13a	·	13b	^	14a	·	14b	^	15
SP1:											-						-														-						-		-
SP2:					-						-
SP3:																	-		-
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for BCAM

2 Ensembl transcripts including schematic representations:

ENST00000270233 ENST00000391955

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

BCAM expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for BCAM

¹ / ² / ³

6 probe-sets matching BCAM gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
40094_r_at²^{, 3}	U95-A	1	1.00	1.00	0.19	0.93	X80026	0.60	0.75	0.68	1
40093_at²^{, 3}	U133-A	1	1.00	1.00	0.95	1.08	X83425	0.80	0.80	0.80	1
40093_at²^{, 3}	U133-A	1	1.00	1.00	--	--	X83425	0.80	0.80	0.80	1
203009_at²^{, 3}	U133-A	2	1.00	0.95	--	--	NM_005581	0.40	0.67	0.55	1
40093_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
203009_at²	U133Plus2	2	1.00	0.95	--	--	--	--	--	--	--

GeneDecks BCAM for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CCCGCCCCCG

SOURCE GeneReport for Unigene cluster: Hs.625725
UniProtKB/Swiss-Prot: LU_HUMAN, P50895
Tissue specificity: Wide tissue distribution (highest in the pancreas and very low in brain).
Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel
walls

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for BCAM gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	BCAM¹	--	basal cell adhesion molecule (Lutheran blood group)	82.96(n) 78.97(a)	484456 XM_541571.2 XP_541571.2
chimpanzee (Pan troglodytes)	BCAM¹	--	basal cell adhesion molecule (Lutheran blood group)	99.38(n) 98.96(a)	744276 XM_001161836.1 XP_001161836.1
cow (Bos taurus)	BCAM¹	--	basal cell adhesion molecule (Lutheran blood group)	82.27(n) 77.39(a)	282862 NM_174741.2 NP_777166.1
rat (Rattus norvegicus)	Bcam¹	--	basal cell adhesion molecule	76.26(n) 73.63(a)	78958 NM_031752.2 NP_113940.1
mouse (Mus musculus)	Bcam^{1, 5}	7⁵	basal cell adhesion molecule^{1, 5}	75.52(n)¹ 73.43(a)¹	57278¹ NM_020486.2¹ NP_065232.1¹ AB035511⁵ AF109160⁵ (see all 16)

About this table Species with no ortholog for BCAM

ENSEMBL Gene Tree for BCAM

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for BCAM gene

MCAM² ALCAM²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

UniProtKB/Swiss-Prot: LU_HUMAN, P50895

Polymorphism: LU is responsible for the Lutheran blood group system

10/122 NCBI SNPs in BCAM are shown (see all 122 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 80)

AB	SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs2967671^1,2	A,C,F,H	50003876(+)	`CGAGTC/GCCCAA`	2	--	ng5¹		6	NS EU EA WA	510
	rs7026^1,2	A,C,F,H	50016356(+)	`CTCCCT/CTGCTG`	1	--	ut3¹ ese³		11	MN NS EU EA WA	1102
	rs2927478^1,2	A,C,F,H	50003363(-)	`GGCCAG/AAGCAG`	2	--	ng5¹		6	NS EU EA WA	494
	rs1135062^1,2	C,F,H	50014584(+)	`TCGGCA/GCCGGT`	2	T/A	mis¹		18	NA NS EU EA	1516
	rs922387^1,2	C,F,H	50003954(-)	`ACCAGC/TGTAGC`	2	--	ng5¹		12	NS EU EA WA	1164
	rs9967601^1,2	C,F,H	50009309(+)	`GGTACG/ACGAGG`	2	H/R	mis¹		6	NS EU EA WA	510
	rs28399654^1,2	C,F	50008428(+)	`TGCCCG/ATAGAG`	2	I/V	mis¹ ese³		2	NS	94
--	rs3669^1,2	C,F	50014913(+)	`ACATCT/CTATCC`	2	--	ut3¹ int¹		3	MN NS	278
	rs28399653^1,2	C,F	50007285(+)	`CCCCCG/ACCTAG`	2	H/R	mis¹ ese³		8	NS	406
	rs28399626^1,2	C,F	50013681(+)	`GTGCAG/ATCGTG`	2	I/V	mis¹ ese³		8	NS	752

About this table

HapMap Linkage Disequilibrium images for BCAM (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 111200

7 Novoseek disease relationships for BCAM gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
carcinoma basal cell	49.49	3	10728810 (1), 15278364 (1), 11121140 (1)
erythroleukemia	48.52	1	10630290 (1)
skin tumor	46.79	3	11121140 (2), 15278364 (1)
colon carcinoma	35.29	1	10542217 (1)
cancer	12.25	3	16584446 (1), 7954395 (1), 10542217 (1)
carcinoma squamous cell	7.78	2	15278364 (1), 11121140 (1)
tumors	0.00	10	11121140 (3), 15278364 (2), 16584446 (1), 15923364 (1)

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Blood Group Antigen Gene Mutation Database (BGMUT) Lutheran blood group system

Human Gene Mutation Database: BCAM
Human Genome Epidemiology Navigator: BCAM (4 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/49 PubMed articles for BCAM gene (see all 49 ):

Molecular cloning of the B-CAM cell surface glycoprotein of epithelial cancers: a novel member of the immunoglobulin superfamily. (PubMed id 7954395)^{1, 3, 4} Campbell I.G....Rettig W.J. (1994)
The Laminin 511/521-binding site on the Lutheran blood group glycoprotein is located at the flexible junction of Ig domains 2 and 3. (PubMed id 17638854)^{3, 4} Mankelow T.J....Anstee D.J. (2007)
Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)^{3, 4} Liu T.... Smith R.D. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. (PubMed id 12754519)^{3, 4} Zhang H.... Aebersold R. (2003)
The Lutheran blood group glycoprotein, another member of the immunoglobulin superfamily, is widely expressed in human tissues and is developmentally regulated in human liver. (PubMed id 7777537)^{3, 4} Parsons S.F.... Anstee D.J. (1995)
A unique gene encodes spliceoforms of the B-cell adhesion molecule cell surface glycoprotein of epithelial cancer and of the Lutheran blood group glycoprotein. (PubMed id 8781446)^{1, 3} Rahuel C....Colin Y. (1996)
Organization of the human LU gene and molecular basis of the Lu(a)/Lu(b) blood group polymorphism. (PubMed id 9192786)^{1, 3} El Nemer W....Le Van Kim C. (1997)
Molecular interactions of B-CAM (basal-cell adhesion molecule) and laminin in epithelial skin cancer. (PubMed id 15278364)^{1, 3} Drewniok C....Schon M.P. (2004)
Laminin-10 and Lutheran blood group glycoproteins in adhesion of human endothelial cells. (PubMed id 16236823)^{1, 3} Vainionpaa N....Virtanen I. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 4059	HGNC: 6722	AceView: LU	Ensembl:ENSG00000187244	euGenes: HUgn4059
ECgene: BCAM	H-InvDB: BCAM

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
dbRBC/BGMUT	http://www.ncbi.nlm.nih.gov/gv/mhc/xslcgi.cgi?cmd=bgmut/systems_info&system=lutheran
SeattleSNPs	http://pga.gs.washington.edu/data/lu/

Licensable Technologies for BCAM
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for BCAM:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for BCAM-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for BCAM		Antibodies for BCAM
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for BCAM		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (BCAM)
	Antibodies (BCAM)
	Chimera RNAi (BCAM)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (CD239)
	Antibodies (CD239)

Search OriGene for BCAM

Search Tocris compounds for BCAM

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for BCAM

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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BCAM Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for BCAM

Summaries
for BCAM

Genomic Location
for BCAM

Proteins
for BCAM

Protein Domains/
Families
for BCAM

Gene Function
for BCAM

Pathways & Interactions
for BCAM

Drugs & Compounds
for BCAM

Transcripts
for BCAM

Expression
for BCAM

Orthologs
for BCAM

Paralogs
for BCAM

SNPs/Variants
for BCAM

Disorders & Mutations
for BCAM

Medical News
for BCAM

Publications
for BCAM

Search for BCAM

Genome Databases showing BCAM

Other Databases showing BCAM

Specialized Databases showing BCAM

Licensable Technologies
for BCAM

Services
for BCAM

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

BCAM Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor BCAM

Summariesfor BCAM

Genomic Locationfor BCAM

Proteinsfor BCAM

Protein Domains/Familiesfor BCAM

Gene Functionfor BCAM

Pathways & Interactionsfor BCAM

Drugs & Compoundsfor BCAM

Transcriptsfor BCAM

Expression for BCAM

Orthologsfor BCAM

Paralogsfor BCAM

SNPs/Variantsfor BCAM

Disorders & Mutationsfor BCAM

Medical Newsfor BCAM

Publicationsfor BCAM

Search for BCAM

Genome Databases showing BCAM

Other Databases showing BCAM

Specialized Databases showing BCAM

Licensable Technologiesfor BCAM

Servicesfor BCAM

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for BCAM

Summaries
for BCAM

Genomic Location
for BCAM

Proteins
for BCAM

Protein Domains/
Families
for BCAM

Gene Function
for BCAM

Pathways & Interactions
for BCAM

Drugs & Compounds
for BCAM

Transcripts
for BCAM

Expression
for BCAM

Orthologs
for BCAM

Paralogs
for BCAM

SNPs/Variants
for BCAM

Disorders & Mutations
for BCAM

Medical News
for BCAM

Publications
for BCAM

Licensable Technologies
for BCAM

Services
for BCAM