BBS7 Gene
protein-coding GIFtS: 50
GCID: GC04M122745
|
|
Bardet-Biedl syndrome 7
| |
Aliases
for BBS7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Bardet-Biedl Syndrome 71 2 | | BBS2L11 2 3 | | BBS2-Like Protein 12 3 | | FLJ107151 | | Bardet-Biedl Syndrome 7 Protein2 | | BBS2-Like 12 |
Export aliases for BBS7 gene to outside databasesPrevious GC identifers: GC04M123028 GC04M123138 GC04M123204 GC04M123103 GC04M122965 GC04M118472 |
Summaries
for BBS7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for BBS7:
This gene encodes one of seven proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8 andBBS9. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSomecomplex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) andCCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whosesymptoms include obesity, retinal degeneration, polydactyly and nephropathy; however, mutations in this gene and theBBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a majorcontributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variantsencoding distinct isoforms have been identified for this gene.(provided by RefSeq, Feb 2011)
UniProtKB/Swiss-Prot: BBS7_HUMAN, Q8IWZ6Function: The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. Thisciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body andcontacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly theBBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of theciliary membrane
Gene Wiki entry for BBS7
|
Genomic Views
for BBS7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BBS7 gene promoter:
TBP Nkx3-1 v4 Cdc5 GATA-1 SRY COMP1 TFIID FOXJ2 (long isoform) Nkx3-1 v3 FOXJ2
Other transcription factors
Search SABiosciences Chromatin IP Primers for BBS7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BBS7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q27 Ensembl cytogenetic band: 4q27 HGNC cytogenetic band: 4q27BBS7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M122745: view genomic region
(about GC identifiers)
Start:
|
122,745,595 bp from pter |
End:
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122,791,652 bp from pter |
Size:
|
46,058 bases |
Orientation:
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minus strand |
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Proteins
for BBS7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BBS7_HUMAN, Q8IWZ6 (See
protein sequence)Recommended Name: Bardet-Biedl syndrome 7 protein Size: 715 amino acids; 80353 Da
Subunit: Part of BBSome complex, that contains BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complexbinds to PCM1 and tubulin. Interacts with BBS2 (via C-terminus). Interacts with CCDC28B
Subcellular location: Cell projection, cilium membrane. Cytoplasm. Note=Localizes to nonmembranous centriolarsatellites in the cytoplasm
Secondary accessions: Q4W5P8 Q8N581 Q9NVI4Alternative splicing: 2 isoforms: Q8IWZ6-1 Q8IWZ6-2 Explore the universe of human proteins at neXtProt for BBS7: NX_Q8IWZ6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IWZ6
BBS7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_060660.2 NP_789794.1
ENSEMBL proteins: ENSP00000264499 ENSP00000423250 ENSP00000423626
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
BBS7 for ontologies About GeneDecksing
BBS7 Antibody Products:
Assay Products for BBS7: |
Protein
Domains /
Families
for BBS7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BBS7 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IWZ6ProtoNet protein and cluster: Q8IWZ6 |
Function
for BBS7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: BBS7_HUMAN, Q8IWZ6Function: The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. Thisciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body andcontacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly theBBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of theciliary membrane
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BBS7 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BBS7 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): BBS7 (NM_176824) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BBS7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BBS7 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BBS7 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
BBS7 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for BBS7:
Animal Models:
Mouse knock-out Bbs7tm1Vcs for BBS7
9 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Bbs7):
BBS7 for phenotypes About GeneDecksing
|
Pathways & Interactions
for BBS7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BBS7
STRING Interaction
Network Preview (showing 5 interactants - click image to see 24)
5/29 Interacting proteins for BBS7 (Q8IWZ61, 3 ENSP000002644994) via UniProtKB, MINT, STRING, and/or I2D (see all 29)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| BBS2 | Q9BXC91, 3, ENSP000002451574 | EBI-1806001,EBI-748297 I2D:
score=2 STRING: ENSP00000245157 | | ALDOB | P050621, 3, ENSP000003639884 | EBI-1806001,EBI-1045507 I2D:
score=1 STRING: ENSP00000363988 | | BBS1 | Q8NFJ91, 3 | EBI-1806001,EBI-1805484 I2D:
score=1 | | JUN | P054121, 3 | EBI-1806001,EBI-852823 I2D:
score=1 | | CLUAP1 | Q96AJ13, ENSP000003443924 | I2D:
score=2 STRING: ENSP00000344392 |
About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
BBS7 for ontologies About GeneDecksing
|
Drugs & Compounds
for BBS7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for BBS7
Search CenterWatch for drugs/clinical trials and news about BBS7
|
Transcripts
for BBS7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BBS7 gene (2 alternative transcripts): NM_018190.3 NM_176824.2 Unigene Cluster for BBS7: Bardet-Biedl syndrome 7 Hs.591694 [show with all ESTs]Unigene Representative Sequence: NM_1768246 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000264499(uc003ied.3) ENST00000507814 ENST00000506636(uc003iee.2)
ENST00000508536 ENST00000505692 ENST00000502444(uc010inq.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BBS7 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BBS7 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): BBS7 (NM_176824) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BBS7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BBS7 |
Additional cDNA sequence: AF521643.1 AF521644.1 AK001577.1 AK308076.1 AK309803.1 BC032691.1 11 DOTS entries: DT.407371 DT.110185 DT.97804822 DT.121256999 DT.121256974 DT.95083764 DT.100779248 DT.100779251 DT.121256987 DT.99996212 DT.95286627 24/31 AceView cDNA sequences (see all 31): BU160062 BQ226004 AL705447 BX491325 BU564492 BE465114 BX505106 BG717780 BG717837 AL712966 AL710947 BX510161 AI216454 BG720664 BQ940332 BI912874 AL712963 BG720363 BI596633 BX479600 BG723685 AW291392 BM693453 BF701436
GeneLoc Exon Structure
|
Expression
for BBS7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BBS7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See BBS7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BBS7
SOURCE GeneReport for Unigene cluster: Hs.591694
UniProtKB/Swiss-Prot: BBS7_HUMAN, Q8IWZ6Tissue specificity: Isoform 2 is ubiquitously expressed. Isoform 1 is expressed in retina, lung, liver, testis, ovary,prostate, small intestine, liver, brain, heart and pancreas
SABiosciences Expression via Pathway-Focused PCR Array including BBS7:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BBS7
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BBS7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BBS7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BBS7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BBS7 |
Orthologs
for BBS7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for BBS7 gene from 7/23 species (see all 23) About this table
ENSEMBL Gene Tree for BBS7 (if available)
TreeFam Gene Tree for BBS7 (if available) |
Paralogs
for BBS7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for BBS7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Human Gene Mutation Database (HGMD): BBS7
Locus Specific Mutation Databases (LSDB): BBS7
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BBS7 |
|
Disorders
/ Diseases
for BBS7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BBS7 for disorders About GeneDecksing
OMIM gene information: 607590
OMIM disorders: 209900
UniProtKB/Swiss-Prot: BBS7_HUMAN, Q8IWZ6
Note=Ciliary dysfunction leads to a broad spectrum of disorders, collectively termed ciliopathies. Overlappingclinical features include retinal degeneration, renal cystic disease, skeletal abnormalities, fibrosis of variousorgan, and a complex range of anatomical and functional defects of the central and peripheral nervous system. Theciliopathy range of diseases includes Meckel-Gruber syndrome, Bardet-Biedl syndrome, Joubert syndrome,nephronophtisis, Senior-Loken syndrome, and Jeune asphyxiating thoracic dystrophy among others. Single-locus allelismis insufficient to explain the variable penetrance and expressivity of such disorders, leading to the suggestion thatvariations across multiple sites of the ciliary proteome, including BBS7, influence the clinical outcome Defects in BBS7 are a cause of Bardet-Biedl syndrome type 7 (BBS7) [MIM:209900]. Bardet-Biedl syndrome (BBS)is a genetically heterogeneous disorder characterized by usually severe pigmentary retinopathy, early onset obesity,polydactyly, hypogenitalism, renal malformation and mental retardation. Secondary features include diabetes mellitus,hypertension and congenital heart disease. A relatively high incidence of BBS is found in the mixed Arab populationsof Kuwait and in Bedouin tribes throughout the Middle East, most likely due to the high rate of consaguinity in thesepopulations and a founder effect. Inheritance is autosomal recessive, but three mutated alleles (two at one locus, anda third at a second locus) may be required for disease manifestation in some cases (triallelic inheritance)
17  diseases for BBS7: About MalaCardsbardet-biedl syndrome bardet-biedl syndrome 7 retinal degeneration mckusick-kaufman syndrome
polydactyly senior-loken syndrome asphyxiating thoracic dystrophy retinitis
obesity pigmentary retinopathy acrocallosal syndrome tetralogy of fallot
nephropathy meckel syndrome joubert syndrome retinal disease
prostatitis
1 disease from the University of Copenhagen DISEASES database for BBS7:Polydactyly 1 Novoseek disease relationship for BBS7 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| bardet-biedl syndrome |
92.9 |
3 |
19093007 (2), 12567324 (1) |
GeneTests: BBS7
Bardet-Biedl Syndrome
Human Genome Epidemiology (HuGE) Navigator: BBS7 (3 documents)
Export disorders for BBS7 gene to outside databases
|
Publications
for BBS7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BBS7 gene, integrated from 9 sources (see all 28):
(articles sorted by number of sources associating them with BBS7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of a novel Bardet-Biedl syndrome protein, BBS7, that shares structural features with BBS1 and BBS2. (PubMed id 12567324)1, 2, 9 Badano J.L....Katsanis N. (2003)
- BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly. (PubMed id 20080638)1, 2 Seo S....Sheffield V.C. (2010)
- A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. (PubMed id 17574030)1, 2 Nachury M.V....Jackson P.K. (2007)
- Dissection of epistasis in oligogenic Bardet-Biedl syndrome. (PubMed id 16327777)1, 2 Badano J.L....Katsanis N. (2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A novel mutation in BBS7 gene causes Bardet-Biedl syndrome in a Chinese family. (PubMed id 19093007)1, 9 Yang Z....Xia Q. (2008)
- KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes. (PubMed id 21552264)2 Putoux A.... Attie-Bitach T. (2011)
- BBS genotype-phenotype assessment of a multiethnic patient cohort calls for a revision of the disease definition. (PubMed id 21344540)2 Deveault C....Heon E. (2011)
|
External Searches for BBS7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BBS7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BBS7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BBS7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for BBS7 | Pharmacogenomics, SNPs, Pathways | | Mutations of the BBS7 gene | http://www.retina-international.org/files/sci-news/bbs7mut.htm | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/BBS7 |
|
| | |
About This Section
| Patent Information for BBS7 gene:
Search GeneIP for patents involving BBS7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BBS7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for BBS7 | | OriGene shRNA RFP for BBS7 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BBS7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BBS7 | | | OriGene Protein Over-expression Lysate for BBS7 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for BBS7 | | OriGene 3'-UTR Clone for BBS7 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BBS7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BBS7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BBS7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BBS7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BBS7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BBS7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BBS7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BBS7 |
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| | | | Search Tocris compounds for BBS7 |
| |  |  |  |  | | | | |
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 | | | BBS7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BBS7 |
|  |  |  | | | | ThermoFisher Antibodies for BBS7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BBS7 |
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