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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BBS12 Gene

protein-coding   GIFtS: 50
GCID: GC04P123653

Bardet-Biedl Syndrome 12

(Previous name: chromosome 4 open reading frame 24)
(Previous symbol: C4orf24)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Bardet-Biedl Syndrome 121 2
C4orf241 2 3 5
Chromosome 4 Open Reading Frame 241
Bardet-Biedl Syndrome 12 Protein2
FLJ356305

External Ids:    HGNC: 266481   Entrez Gene: 1663792   Ensembl: ENSG000001810047   OMIM: 6106835   UniProtKB: Q6ZW613   

Export aliases for BBS12 gene to outside databases

Previous GC identifers: GC04P123874 GC04P119380


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for BBS12 Gene:
The protein encoded by this gene is part of a complex that is involved in membrane trafficking. The encoded
protein is a molecular chaperone that aids in protein folding upon ATP hydrolysis. This protein also plays a role
in adipocyte differentiation. Defects in this gene are a cause of Bardet-Biedl syndrome type 12. Two transcript
variants encoding the same protein have been found for this gene. (provided by RefSeq, May 2010)

GeneCards Summary for BBS12 Gene: 
BBS12 (Bardet-Biedl syndrome 12) is a protein-coding gene. Diseases associated with BBS12 include bbs12-related bardet-biedl syndrome, and bardet-biedl syndrome 12. GO annotations related to this gene include protein binding and ATP binding.

UniProtKB/Swiss-Prot: BBS12_HUMAN, Q6ZW61
Function: Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the
BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating
transports vesicles to the cilia. Involved in adipogenic differentiation

Gene Wiki entry for BBS12 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.2  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BBS12 gene promoter:
         HSF1 (long)   CUTL1   NF-AT   NF-AT4   NF-AT2   HFH-1   FOXO4   NF-AT3   HSF1short   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBBS12 promoter sequence
   Search SABiosciences Chromatin IP Primers for BBS12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BBS12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q27   Ensembl cytogenetic band:  4q27   HGNC cytogenetic band: 4q27

BBS12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BBS12 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P123653:  view genomic region     (about GC identifiers)

Start:
123,653,857 bp from pter      End:
123,666,098 bp from pter
Size:
12,242 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: BBS12_HUMAN, Q6ZW61 (See protein sequence)
Recommended Name: Bardet-Biedl syndrome 12 protein  
Size: 710 amino acids; 79085 Da
Subunit: Component of the BBS/CCT complex composed at least of MKKS, BBS10, BBS12, TCP1, CCT2, CCT3, CCT4, CCT5
AND CCT8
Subcellular location: Cell projection, cilium. Note=Located within the basal body of the primary cilium of
differentiating preadipocytes
Miscellaneous: Adipocytes derived from BBS-patients' dermal fibroblasts in culture exhibit higher propensity for
fat accumulation when compared to controls. This strongly suggests that a peripheral primary dysfunction of
adipogenesis participates to the pathogenesis of obesity in BBS
Sequence caution: Sequence=BAC04006.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: D3DNX5 Q7Z342 Q7Z482 Q8NAB8

Explore the universe of human proteins at neXtProt for BBS12: NX_Q6ZW61

Explore proteomics data for BBS12 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6ZW61

  • BBS12 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    BBS12 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001171478.1  NP_689831.2  

    ENSEMBL proteins: 
     ENSP00000319062   ENSP00000398912   ENSP00000438273  

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    Cloud-Clone Corp. Proteins for BBS12 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005929cilium IEA--

    BBS12 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CHAP: Heat Shock Proteins / Chaperonins

    3 InterPro protein domains:
     IPR027409 GroEL-like_apical_dom
     IPR002423 Cpn60/TCP-1
     IPR027413 GROEL-like_equatorial

    Graphical View of Domain Structure for InterPro Entry Q6ZW61

    ProtoNet protein and cluster: Q6ZW61

    UniProtKB/Swiss-Prot: BBS12_HUMAN, Q6ZW61
    Similarity: Belongs to the TCP-1 chaperonin family. BBS12 subfamily


    BBS12 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BBS12_HUMAN, Q6ZW61
    Function: Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the
    BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating
    transports vesicles to the cilia. Involved in adipogenic differentiation

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0005524ATP binding IEA--
         
    BBS12 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for BBS12:
     Increased S DNA content 

         9 MGI mutant phenotypes (inferred from 1 allele(MGI details for Bbs12):
     adipose tissue  behavior/neurological  growth/size  homeostasis/metabolism  immune system 
     nervous system  renal/urinary system  skeleton  vision/eye 

    BBS12 for phenotypes           About GeneDecksing

    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidBBS12 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BBS12


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BBS12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/7 Interacting proteins for BBS12 (Q6ZW611 ENSP000003190624) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BBS7Q8IWZ61, ENSP000002644994EBI-6128352,EBI-1806001 STRING: ENSP00000264499
    MKKSQ9NPJ11, ENSP000002460624EBI-6128352,EBI-721319 STRING: ENSP00000246062
    BBS9Q3SYG41, ENSP000002420674EBI-6128352,EBI-2826852 STRING: ENSP00000242067
    BBS10Q8TAM11, ENSP000003769464EBI-6128352,EBI-6128013 STRING: ENSP00000376946
    BBS2ENSP000002451574STRING: ENSP00000245157
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0044267cellular protein metabolic process IEA--
    GO:0051131chaperone-mediated protein complex assembly IMP--

    BBS12 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BBS12

    Search CenterWatch for drugs/clinical trials and news about BBS12

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BBS12 gene (2 alternative transcripts): 
    NM_001178007.1  NM_152618.2  

    Unigene Cluster for BBS12:

    Bardet-Biedl syndrome 12
    Hs.400698  [show with all ESTs]
    Unigene Representative Sequence: NM_001178007
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000314218(uc003ieu.3) ENST00000433287 ENST00000542236(uc021xrm.1)

    miRNA
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    hsa-miR-3140-3p hsa-miR-3647-3p hsa-miR-3137 hsa-miR-370 hsa-miR-194 hsa-miR-802 hsa-miR-548u hsa-miR-664*
    SwitchGear 3'UTR luciferase reporter plasmidBBS12 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BBS12

    Additional mRNA sequence: 

    AK092949.1 AK123553.1 BC055426.1 BC065708.1 BX538148.1 

    3 DOTS entries:

    DT.101981052  DT.100735471  DT.95154890 

    24/46 AceView cDNA sequences (see all 46):

    BE350042 NM_152618 W37243 AW205835 CA429237 BM931203 BX105161 CD359068 
    AA745881 AA421754 AA039684 BX106026 AK123553 BU678215 AK092949 AI244311 
    BU657035 AA594464 BM712647 AI969474 BI548540 BC065708 AI864276 BI771710 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for BBS12    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b
    SP1:                              
    SP2:              -               


    ECgene alternative splicing isoforms for BBS12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BBS12 expression in normal human tissues (normalized intensities)      BBS12 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGTATGCCAC
    BBS12 Expression
    About this image


    BBS12 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Eye (Sensory Organs)
             Mature Rod Cells Outer Nuclear Layer

    See BBS12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BBS12

    SOURCE GeneReport for Unigene cluster: Hs.400698
        SABiosciences Custom PCR Arrays for BBS12
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for BBS12 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bbs121 , 5 Bardet-Biedl syndrome 12 (human)1, 5 80.32(n)1
    69.07(a)1
      3 (18.41 cM)5
    2419501  NM_001008502.21  NP_001008502.21 
     373125545 
    chicken
    (Gallus gallus)
    Aves BBS121 Bardet-Biedl syndrome 12 56.76(n)
    47.43(a)
      422667  XM_420621.3  XP_420621.2 
    lizard
    (Anolis carolinensis)
    Reptilia BBS126
    Uncharacterized protein
    43(a)
    1 ↔ 1
    5(138649239-138651401)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.156122 Xenopus laevis transcribed sequences 73.56(n)    BJ060932.1 
    zebrafish
    (Danio rerio)
    Actinopterygii bbs121 Bardet-Biedl syndrome 12 48.71(n)
    37.67(a)
      570583  XM_002667206.1  XP_002667252.1 


    ENSEMBL Gene Tree for BBS12 (if available)
    TreeFam Gene Tree for BBS12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/343 SNPs in BBS12 are shown (see all 343)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0629654
    Bardet-Biedl syndrome 12 (BBS12)4--see VAR_0629652 T M mis40--------
    VAR_0662664
    Bardet-Biedl syndrome 12 (BBS12)4--see VAR_0662662 L R mis40--------
    VAR_0662704
    Bardet-Biedl syndrome 12 (BBS12)4--see VAR_0662702 R Q mis40--------
    VAR_0349224
    Bardet-Biedl syndrome 12 (BBS12)4--see VAR_0349222 P L mis40--------
    VAR_0662774
    Bardet-Biedl syndrome 12 (BBS12)4--see VAR_0662772 R C mis40--------
    VAR_0629644
    Bardet-Biedl syndrome 12 (BBS12)4--see VAR_0629642 I T mis40--------
    VAR_0349324
    Bardet-Biedl syndrome 12 (BBS12)4--see VAR_0349322 G V mis40--------
    VAR_0662694
    Bardet-Biedl syndrome 12 (BBS12)4--see VAR_0662692 Q E mis40--------
    VAR_0662714
    Bardet-Biedl syndrome 12 (BBS12)4--see VAR_0662712 V M mis40--------
    VAR_0662754
    Bardet-Biedl syndrome 12 (BBS12)4--see VAR_0662752 R H mis40--------

    HapMap Linkage Disequilibrium report for BBS12 (123653857 - 123666098 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for BBS12: --

    Human Gene Mutation Database (HGMD): BBS12

    Locus Specific Mutation Databases (LSDB): BBS12
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing BBS12
    DNA2.0 Custom Variant and Variant Library Synthesis for BBS12

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610683   
    OMIM disorders: 209900  
    UniProtKB/Swiss-Prot: BBS12_HUMAN, Q6ZW61
  • Bardet-Biedl syndrome 12 (BBS12) [MIM:209900]: A syndrome characterized by usually severe pigmentary
    retinopathy, early-onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation.
    Secondary features include diabetes mellitus, hypertension and congenital heart disease. Bardet-Biedl syndrome
    inheritance is autosomal recessive, but three mutated alleles (two at one locus, and a third at a second locus)
    may be required for clinical manifestation of some forms of the disease. Note=The disease is caused by mutations
    affecting the gene represented in this entry

  • 10 diseases for BBS12:    About MalaCards
    bbs12-related bardet-biedl syndrome    bardet-biedl syndrome 12    pigmentary retinopathy    bardet-biedl syndrome
    fundus dystrophy    polydactyly    obesity    mental retardation
    diabetes mellitus    hypertension

    3 diseases from the University of Copenhagen DISEASES database for BBS12:
    Bardet-Biedl syndrome     Polydactyly     Fundus dystrophy

    BBS12 for disorders           About GeneDecksing

    GeneTests: BBS12
    GeneReviews: BBS12

    Export disorders for BBS12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BBS12 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with BBS12)
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    1. Identification of a novel BBS gene (BBS12) highlights the major role of a vertebrate-specific branch of chaperonin-related proteins in Bardet-Biedl syndrome. (PubMed id 17160889)1, 2, 3 Stoetzel C.... Dollfus H. (2007)
    2. Transient ciliogenesis involving Bardet-Biedl syndrome proteins is a fundamental characteristic of adipogenic differentiation. (PubMed id 19190184)1, 2 Marion V.... Dollfus H. (2009)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. BBS-induced ciliary defect enhances adipogenesis, caus ing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflamm atory response. (PubMed id 22958920)1 Marion V....Dollfus H. (2012)
    5. BBS genotype-phenotype assessment of a multiethnic patient cohort calls for a revision of the disease definition. (PubMed id 21344540)2 Deveault C....Heon E. (2011)
    6. Chaperonin genes on the rise: new divergent classes a nd intense duplication in human and other vertebrate genomes. (PubMed id 20193073)1 Mukherjee K....Brocchieri L. (2010)
    7. Two sibs with Bardet-Biedl syndrome due to mutations in BBS12: no clues for modulation by a third mutation in BBS10. (PubMed id 20827784)1 Dulfer E....van Essen A.J. (2010)
    8. Mutations in chaperonin-like BBS genes are a major co ntributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. (PubMed id 20472660)1 Billingsley G....HAcon E. (2010)
    9. BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly. (PubMed id 20080638)2 Seo S....Sheffield V.C. (2010)
    10. Bardet-Biedl syndrome in Denmark--report of 13 novel sequence variations in six genes. (PubMed id 20120035)2 Hjortshoj T.D.... Brondum-Nielsen K. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 166379 HGNC: 26648 AceView: FLJ35630 Ensembl:ENSG00000181004 euGenes: HUgn166379
    ECgene: BBS12 H-InvDB: BBS12

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BBS12 Pharmacogenomics, SNPs, Pathways
    GeneReviewshttp://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/BBS12

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BBS12 gene:
    Search GeneIP for patents involving BBS12

    GeneCards and IP:
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