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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BARX1 Gene

protein-coding   GIFtS: 53
GCID: GC09M096713

BARX homeobox 1

(Previous name: BarH-like homeobox 1 )
 Explore 6 diseases affiliated with
BARX1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for BARX1    

Aliases
for BARX1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
BARX Homeobox 11 2
BarH-Like Homeobox 11 2
Homeobox Protein BarH-Like 12

External Ids:    HGNC: 9551   Entrez Gene: 560332   Ensembl: ENSG000001316687   OMIM: 6032605   UniProtKB: Q9HBU13   

Export aliases for BARX1 gene to outside databases

Previous GC identifers: GC09M087540 GC09M088441 GC09M090013 GC09M092055 GC09M093793 GC09M095753 GC09M066390


Summaries
for BARX1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for BARX1:
This gene encodes a member of the Bar subclass of homeobox transcription factors. Studies of the mouse and chick
homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest
origin. The protein may also be associated with differentiation of stomach epithelia. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: BARX1_HUMAN, Q9HBU1
Function: Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach
organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal
Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter




Genomic Views
for BARX1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008470.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BARX1 gene promoter:
         Max1   RP58   NF-1/L   NF-1   STAT5A   IRF-1   Nkx2-5   AP-2gamma   AREB6   c-Myc   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for BARX1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BARX1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q12   Ensembl cytogenetic band:  9q22.32   HGNC cytogenetic band: 9q22.32

BARX1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BARX1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M096713:  view genomic region     (about GC identifiers)

Start:
 96,713,628 bp from pter      End:
 96,717,654 bp from pter
Size:
 4,027 bases      Orientation:
 minus strand

Proteins
for BARX1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: BARX1_HUMAN, Q9HBU1 (See protein sequence)
Recommended Name: Homeobox protein BarH-like 1  
Size: 254 amino acids; 27298 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=AAG23738.1; Type=Frameshift; Positions=Several;
1 PDB 3D structure from and Proteopedia for BARX1:
2DMT (3D)    
Secondary accessions: Q6P2R4 Q96GH8
Alternative splicing: 2 isoforms:  Q9HBU1-1   Q9HBU1-2   

Explore the universe of human proteins at neXtProt for BARX1: NX_Q9HBU1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9HBU1

    • BARX1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_067545.3  
    ENSEMBL proteins: 
     ENSP00000253968   ENSP00000385613  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: BARX1
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    Novus Biologicals BARX1 Protein
    Novus Biologicals BARX1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for BARX1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000228nuclear chromosome NAS--


    BARX1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for BARX1

    Protein Domains /
    Families
    for BARX1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    BARX1 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR000047 HTH_motif
     IPR017970 Homeobox_CS
     IPR001356 Homeodomain
     IPR020479 Homeobox_metazoa
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q9HBU1

    ProtoNet protein and cluster: Q9HBU1

    1 Blocks protein family: IPB000047 Lambda and other repressor helix-turn-helix signature

    UniProtKB/Swiss-Prot: BARX1_HUMAN, Q9HBU1
    Similarity: Belongs to the BAR homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    Function
    for BARX1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: BARX1_HUMAN, Q9HBU1
    Function: Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach
    organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal
    Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter

    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BARX1
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate BARX1:
    hsa-miR-3163 hsa-miR-550a hsa-miR-597 hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmid: BARX1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BARX1 (see all 7)
    OriGene shRNA RFP: BARX1
    OriGene siRNA: BARX1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BARX1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for BARX1

    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BARX1 

    Cell Line
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    LifeMap BioReagents: cell lines associated with BARX1: PureStem 4D20.8, NCr-fac Progenitor,
    PureStem 7PEND24, NCr-fac & Meso-prx Progenitor

    In Situ Assay
    Products:       
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for BARX1

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000976transcription regulatory region sequence-specific DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity NAS10995576


    BARX1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for BARX1:
     Decreased homologous recombina 

    Animal Models:
         Mouse knock-out Barx1tm1Shiv for BARX1
         4 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Barx1):
     cellular  craniofacial  digestive/alimentary  mortality/aging 

    BARX1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for BARX1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BARX1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/8 Interacting proteins for BARX1 (Q9HBU12, 3 ENSP000002539684) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK6Q166592, 3MINT-8260757 I2D: score=2 
    RPS6KA3P518122, 3, ENSP000003688844MINT-8269516 I2D: score=2 STRING: ENSP00000368884
    SFRP2Q96HF13, ENSP000002740634I2D: score=1 STRING: ENSP00000274063
    SFRP1Q8N4743, ENSP000002207724I2D: score=1 STRING: ENSP00000220772
    DLX1P561773I2D: score=1 
    About this table

    Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent NAS--
    GO:0007267cell-cell signaling IEA--
    GO:0007275multicellular organismal development NAS--
    GO:0009888tissue development ----


    BARX1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for BARX1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BARX1
    Search CenterWatch for drugs/clinical trials and news about BARX1 

    Transcripts
    for BARX1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for BARX1 gene: 
    NM_021570.3  

    Unigene Cluster for BARX1:

    BARX homeobox 1
    Hs.164960  [show with all ESTs]
    Unigene Representative Sequence: BM563421
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000253968(uc010mrh.3) ENST00000401724(uc004aud.3)

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BARX1
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate BARX1:
    hsa-miR-3163 hsa-miR-550a hsa-miR-597 hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmid: BARX1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BARX1 (see all 7)
    OriGene shRNA RFP: BARX1
    OriGene siRNA: BARX1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BARX1
    Clone
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    GenScript: all cDNA clones in your preferred vector: BARX1 (NM_021570)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BARX1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BARX1 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BARX1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BARX1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BARX1

    Additional cDNA sequence: 

    AF213356.1 BC009458.1 BC064363.1 

    2 DOTS entries:

    DT.100016619  DT.303297 

    24/34 AceView cDNA sequences (see all 34):

    BE464546 BC064363 AI445581 AI623151 AW514391 CR592249 AW130310 AI440279 
    BG829554 BX094328 BM453164 BM738686 AI459280 BF981618 AI292221 BC009458 
    BE883480 BU624499 AA506079 BG896578 AA442582 BE266464 NM_021570 AL577926 

    GeneLoc Exon Structure


    Expression
    for BARX1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BARX1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCTGGAGGCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    BARX1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    4 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Head MesenchymeBranchial Arch 1Cranial Neural Crest CellsNeural Crest
    Head MesenchymeBranchial Arch 2Cranial Neural Crest CellsNeural Crest
    BoneMandibular ProcessBone
    BoneMaxillary ProcessBone
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    PureStem™ mesenchymal progenitor 7PEND24 (Embryonic Progenitor Cell)Cartilage, Neural Crest
    PureStem™ mesenchymal progenitor 4D20.8 (Embryonic Progenitor Cell)Lateral Plate Mesoderm, Neural Crest

    See BARX1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BARX1

    SOURCE GeneReport for Unigene cluster: Hs.164960

    UniProtKB/Swiss-Prot: BARX1_HUMAN, Q9HBU1
    Tissue specificity: Widely expressed. Expressed at higher levels in testis and heart. Detected in craniofacial tissue
    and adult iris, but not in lymphocytes, fibroblasts, choroid retina, retinal pigment epithelium, kidney, or fetal
    liver

        SABiosciences Expression via Pathway-Focused PCR Array including BARX1: 
              Homeobox (HOX) Genes in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for BARX1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for BARX1 gene from 3/14 species (see all 14)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves BARX11 BARX homeobox 1 80.57(n)
    82.59(a)    		   374017  NM_204193.1  NP_989524.1 
    lizard
    (Anolis carolinensis)    		 Reptilia BARX16
    		 --
    		 71(a)
    		 1 ↔ 1
    		 GL343225.1(878823-896653)
    zebrafish
    (Danio rerio)    		 Actinopterygii barx11 BarH-like homeobox 1 66.08(n)
    74.12(a)    		   553644  NM_001024949.1  NP_001020120.1 


    ENSEMBL Gene Tree for BARX1 (if available)
    TreeFam Gene Tree for BARX1 (if available) 

    Paralogs
    for BARX1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BARX1 gene
    DLX22  BSX2  DLX52  DLX62  BARHL22  BARHL12  DLX42  BARX22  
    DLX12  MSX22  MSX12  DLX32  
    8 SIMAP similar genes for BARX1 using alignment to 1 protein entry:     BARX1_HUMAN:
    HOXA4    BARX2    HMX2    DLX6    HLX    DLX1
    HOXB1    DLX3

    BARX1 for paralogs           About GeneDecksing



    Genomic Variants
    for BARX1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: BARX1_HUMAN, Q9HBU1
    Polymorphism: The polymorphism is not associated with Axenfeld-Reiger syndrome (ARS), iridogoniodysgenesis syndrome
    (IGDS) or related ocular malformations


    10/58 NCBI SNPs in BARX1 are shown (see all 58)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs117933241,2
    		C,F,H,--96713690(+) GGCCCC/TTCACG 1 -- ds500120Minor allele frequency- T:0.18NS EA NA CSA WA 2330
    rs574835691,2
    		C,F,--96713749(+) CCGTGC/TCTAGC 1 -- ds50013Minor allele frequency- T:0.05WA CSA 122
    rs1168600241,2
    		F,--96714028(+) GCAATC/TTCAGG 1 -- ut311Minor allele frequency- T:0.07NA 120
    rs10577151,2
    		C,--96714119(-) TCTGGG/AGCCTG 1 -- ut316Minor allele frequency- A:0.13MN NA WA EA 546
    rs10577131,2
    		C,F,A,H,--96714161(-) ACGCGT/CATTCA 1 -- ut31 ese323Minor allele frequency- C:0.33MN NS EA NA WA CSA 2534
    rs1825997081,2
    		--96714162(+) GAATAA/CGCGTG 1 -- ut310--------
    rs1880096891,2
    		--96714251(+) CAGAAA/GCGCGC 1 -- ut310--------
    rs593971231,2
    		C,--96714338(+) AAAGGC/TTTAGG 1 -- ut315Minor allele frequency- T:0.09WA CSA NA EA 361
    rs22978351,2
    		C,F,--96714429(+) GGCCCC/AGCACC 1 -- ut31 ese35Minor allele frequency- A:0.07EA NA CSA EU 2099
    rs1995273591,2
    		C,--96714454(+) GTCCTC/TGCGGC 2 K E mis10--------

    HapMap Linkage Disequilibrium report for BARX1 (96713628 - 96717654 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for BARX1: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BARX1
    DNA2.0 Custom Variant and Variant Library Synthesis for BARX1

    Disorders / Diseases
    for BARX1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    BARX1 for disorders           About GeneDecksing

    OMIM gene information: 603260    OMIM disorders: --

    6 diseases for BARX1:    About MalaCards
    cleft lip/palate    cleft lip    hearing loss    choroiditis
    retinitis    iridogoniodysgenesis

    1 disease from the University of Copenhagen DISEASES database for BARX1:
    Hard palate cancer
    Human Genome Epidemiology (HuGE) Navigator: BARX1 (2 documents)

    Export disorders for BARX1 gene to outside databases

    Publications
    for BARX1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BARX1 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with BARX1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, characterization, localization, and mutational screening of the human BARX1 gene. (PubMed id 10995576)1, 2, 9 Gould D.B. and Walter M.A. (2000)
    2. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    3. Maternal genes and facial clefts in offspring: a comp rehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PubMed id 20634891)1 Jugessur A....Murray J.C. (2010)
    4. Barx1, growth factors and apoptosis in facial tissue of children with clefts. (PubMed id 18708738)1 Krivicka-Uzkurele B....Akota I. (2008)
    5. Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. (PubMed id 18978678)1 Vieira A.R....Marazita M.L. (2008)
    6. Absence of PITX2, BARX1, and FOXC1 mutations in De Hauwere syndrome (Axenfeld-Rieger anomaly, hydrocephaly, hearing loss): a 25-year follow up. (PubMed id 17486624)1 Lowry R.B....Savage P.R. (2007)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)2 Humphray S.J.... Dunham I. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Transformation of tooth type induced by inhibition of BMP signaling. (PubMed id 9804553)2 Tucker A.S.... Sharpe P.T. (1998)

    External Searches for BARX1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing BARX1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56033 HGNC: 955 AceView: BARX1 Ensembl:ENSG00000131668 euGenes: HUgn56033
    ECgene: BARX1 H-InvDB: BARX1

    Other Databases showing BARX1 gene

    (According to HUGE)
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    Specialized Databases showing BARX1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BARX1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
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    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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     BARX1 Proteins, Antibodies, CLIAs, and ELISAs
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