External Ids for BARX1 Gene
Previous GeneCards Identifiers for BARX1 Gene
This gene encodes a member of the Bar subclass of homeobox transcription factors. Studies of the mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. [provided by RefSeq, Jul 2008]
GeneCards Summary for BARX1 Gene
BARX1 (BARX Homeobox 1) is a Protein Coding gene. Diseases associated with BARX1 include Gastritis, Familial Giant Hypertrophic and Iridogoniodysgenesis, Type 2. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is BARX2.
UniProtKB/Swiss-Prot for BARX1 Gene
Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter.