Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BARHL2 Gene

protein-coding   GIFtS: 43
GCID: GC01M091177

BarH-Like Homeobox 2

(Previous name: BarH (Drosophila)-like 2)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
BarH-Like Homeobox 21 2
BarH (Drosophila)-Like 21
BarH-Like 2 Homeobox Protein2

External Ids:    HGNC: 9541   Entrez Gene: 3434722   Ensembl: ENSG000001430327   OMIM: 6052125   UniProtKB: Q9NY433   

Export aliases for BARHL2 gene to outside databases

Previous GC identifers: GC01U990337 GC01M090353 GC01M090514 GC01M090644 GC01M090889 GC01M089296


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for BARHL2 Gene: 
BARHL2 (BarH-like homeobox 2) is a protein-coding gene. Diseases associated with BARHL2 include neuronitis. GO annotations related to this gene include sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription. An important paralog of this gene is DLX2.

UniProtKB/Swiss-Prot: BARH2_HUMAN, Q9NY43
Function: Potential regulator of neural basic helix-loop-helix genes (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BARHL2 gene promoter:
         E2F-3a   E2F-4   E2F-5   E2F   E2F-1   NRSF form 1   E2F-2   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBARHL2 promoter sequence
   Search SABiosciences Chromatin IP Primers for BARHL2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BARHL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p22.2   Ensembl cytogenetic band:  1p22.2   HGNC cytogenetic band: 1p22.2

BARHL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BARHL2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M091177:  view genomic region     (about GC identifiers)

Start:
91,177,096 bp from pter      End:
91,182,794 bp from pter
Size:
5,699 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: BARH2_HUMAN, Q9NY43 (See protein sequence)
Recommended Name: BarH-like 2 homeobox protein  
Size: 387 amino acids; 41981 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: A0AVP2 Q7Z4N7

Explore the universe of human proteins at neXtProt for BARHL2: NX_Q9NY43

Explore proteomics data for BARHL2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NY43

  • BARHL2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    BARHL2 Protein Expression
    REFSEQ proteins: NP_064447.1  
    ENSEMBL proteins: 
     ENSP00000359474  

    Human Recombinant Protein Products for BARHL2: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for BARHL2
    OriGene Protein Over-expression Lysate for BARHL2
    OriGene MassSpec for BARHL2 
    OriGene Custom Protein Services for BARHL2
    GenScript Custom Purified and Recombinant Proteins Services for BARHL2
    Novus Biologicals BARHL2 Protein
    Novus Biologicals BARHL2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for BARHL2 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    BARHL2 for ontologies           About GeneDecksing



    BARHL2 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for BARHL2
    GenScript Custom Superior Antibodies Services for BARHL2
    Novus Biologicals BARHL2 Antibody
    Abcam antibodies for BARHL2
    Cloud-Clone Corp. Antibodies for BARHL2 
    ThermoFisher Antibodies for BARHL2
    LSBio Antibodies in human, mouse, rat for BARHL2 

    Assay Products for BARHL2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for BARHL2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for BARHL2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for BARHL2 
    Cloud-Clone Corp. CLIAs for BARHL2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    NKL: Homeoboxes / ANTP class : NKL subclass

    4 InterPro protein domains:
     IPR017970 Homeobox_CS
     IPR001356 Homeodomain
     IPR020479 Homeobox_metazoa
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q9NY43

    ProtoNet protein and cluster: Q9NY43

    1 Blocks protein domain: IPB000047 Lambda and other repressor helix-turn-helix signature

    UniProtKB/Swiss-Prot: BARH2_HUMAN, Q9NY43
    Similarity: Belongs to the BAR homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    BARHL2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BARH2_HUMAN, Q9NY43
    Function: Potential regulator of neural basic helix-loop-helix genes (By similarity)

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IEA--
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity ----
    GO:0043565sequence-specific DNA binding IEA--
         
    BARHL2 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for BARHL2:
     Decreased influenza A H1N1 (A/  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r 

         5 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Barhl2):
     behavior/neurological  growth/size  mortality/aging  nervous system  vision/eye 

    BARHL2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for BARHL2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for BARHL2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BARHL2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for BARHL2 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BARHL2
    1 QIAGEN miScript miRNA Assays for microRNA that regulate BARHL2:
    hsa-miR-3175
    SwitchGear 3'UTR luciferase reporter plasmidBARHL2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for BARHL2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BARHL2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for BARHL2
    Sirion Biotech Customized adenovirus for overexpression of BARHL2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for BARHL2 (see all 7)
    OriGene ORF clones in mouse, rat for BARHL2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: BARHL2 (NM_020063)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BARHL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BARHL2
    Sirion Biotech Customized lentivirus for stable overexpression of BARHL2 
                         Customized lentivirus expression plasmids for stable overexpression of BARHL2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for BARHL2
    Search LifeMap BioReagents cell lines for BARHL2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BARHL2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BARHL2

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001709cell fate determination IEA--
    GO:0001764neuron migration IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0006357regulation of transcription from RNA polymerase II promoter ----
    GO:0007399nervous system development ----

    BARHL2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BARHL2 (BARH2)

    Search CenterWatch for drugs/clinical trials and news about BARHL2 / BARH2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BARHL2 gene: 
    NM_020063.1  

    Unigene Cluster for BARHL2:

    BarH-like homeobox 2
    Hs.451956
    Unigene Representative Sequence: AY338397
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000370445(uc001dns.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BARHL2
    1 QIAGEN miScript miRNA Assays for microRNA that regulate BARHL2:
    hsa-miR-3175
    SwitchGear 3'UTR luciferase reporter plasmidBARHL2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for BARHL2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BARHL2
    Clone
    Products:
         
    OriGene clones in human, mouse for BARHL2 (see all 7)
    OriGene ORF clones in mouse, rat for BARHL2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: BARHL2 (NM_020063)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BARHL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BARHL2
    Sirion Biotech Customized lentivirus for stable overexpression of BARHL2 
                         Customized lentivirus expression plasmids for stable overexpression of BARHL2 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for BARHL2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BARHL2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BARHL2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BARHL2

    Additional mRNA sequence: 

    AY338397.1 BC126439.1 BC126441.1 

    1 DOTS entry:

    DT.101976129 

    2 AceView cDNA sequences:

    NM_020063 AY338397 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BARHL2 expression in normal human tissues (normalized intensities)      BARHL2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACCGGACTC
    BARHL2 Expression
    About this image


    BARHL2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 9 entries
             Thalamus
             brain/midbrain/lateral wall   
     
     Eye (Sensory Organs)    fully expand to see all 7 entries
             Late Immature Amacrine Cells Inner Nuclear Layer
             Retina
             retinal progenitor cell e12.5   
     
     Neural Tube (Nervous System)    fully expand to see all 6 entries
             Telencephalon
             spinal cord/lateral wall/ventricular layer   
     
     Spinal Cord (Nervous System)    fully expand to see all 2 entries
             spinal cord/lateral wall/ventricular layer   

     -- (Nervous System)
             mouse/organ system/nervous system/central nervous system   

    See BARHL2 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.451956
        SABiosciences Custom PCR Arrays for BARHL2
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for BARHL2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BARHL2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BARHL2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BARHL2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BARHL2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for BARHL2 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Barhl21 , 5 BarH-like 2 (Drosophila)1, 5 89.33(n)1
    93.96(a)1
      5 (51.43 cM)5
    1043821  NM_001005477.11  NP_001005477.11 
     1064525145 
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3981822 Bar homeobox protein XBH1 76.43(n)    AF283691.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.169342 Danio rerio barH-class homeodomain transcription factor more 75.22(n)    AY145141.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG110856
    B-H16
    (see all 3)
    BarH1
    (see all 3)
    23(a)
    20(a)
    (see all 3)
    possible ortholog
    many ↔ many
    (see all 3)
    X(12510349-12515251)
    X(17291534-17297312)
    worm
    (Caenorhabditis elegans)
    Secernentea ceh-301 Protein CEH-30 51.16(n)
    51.74(a)
      191620  NM_076123.2  NP_508524.2 


    ENSEMBL Gene Tree for BARHL2 (if available)
    TreeFam Gene Tree for BARHL2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BARHL2 gene
    DLX22  BARX12  NKX1-12  VENTX2  BARHL12  BARX22  DLX12  DLX32  
    LBX22  NKX1-22  BSX2  DLX52  DLX62  DLX42  LBX12  MSX22  
    MSX12  
    2 SIMAP similar genes for BARHL2 using alignment to 1 protein entry:     BARH2_HUMAN:
    HLX    BARHL1

    BARHL2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/174 SNPs in BARHL2 are shown (see all 174)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1495036231,2
    --91177138(+) AATCAC/GAAAAA 1 -- ds50010--------
    rs1855651491,2
    --91177175(+) TTTTAC/GTGAAT 1 -- ds50010--------
    rs1875992521,2
    --91177245(+) GACAAC/TATATA 1 -- ds50010--------
    rs9153961,2
    F,A--91177462(+) CTGCCT/AGTGCT 1 -- ds5001 ese32Minor allele frequency- A:0.25NA 4
    rs1925497801,2
    --91177483(+) CGTGCC/TCTTCT 1 -- ds50010--------
    rs75387801,2
    C--91177617(+) TCAGCA/GTTTTC 1 -- ut310--------
    rs23906061,2
    C,F,O,A,H--91177647(+) GGGAGA/CTTTCC 1 -- ut3125Minor allele frequency- C:0.42NS EA NA WA CSA 2186
    rs1900291751,2
    C--91177864(+) TGCAAA/TGTTTT 1 -- ut310--------
    rs2003999761,2
    --91177898(+) GATGGA/GGCTGG 2 P S mis10--------
    rs3745971571,2
    C--91177957(+) GCACAC/TGGGGC 2 H R mis10--------

    HapMap Linkage Disequilibrium report for BARHL2 (91177096 - 91182794 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for BARHL2: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing BARHL2
    DNA2.0 Custom Variant and Variant Library Synthesis for BARHL2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605212    OMIM disorders: --

    2 diseases for BARHL2:    About MalaCards
    neuronitis    


    BARHL2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): BARHL2

    Export disorders for BARHL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BARHL2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with BARHL2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Barhl1, a gene belonging to a new subfamily of mammalian homeobox genes, is expressed in migrating neurons of the CNS. (PubMed id 10814725)1, 2 Bulfone A.... Banfi S. (2000)
    3. Genome-wide association study of lung function decline in adults with and without asthma. (PubMed id 22424883)4 Imboden M....Probst-Hensch N.M. (2012)
    4. A genome-wide association study identifies a novel ma jor locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. (PubMed id 19875614)4 Paterson A.D....Bull S.B. (2010)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    6. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 343472 HGNC: 954 AceView: BARHL2 Ensembl:ENSG00000143032 euGenes: HUgn343472
    ECgene: BARHL2 H-InvDB: BARHL2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BARHL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BARHL2 gene:
    Search GeneIP for patents involving BARHL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for BARHL2  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for BARHL2  
     OriGene MassSpec something-or-other for BARHL2   OriGene clones in human, mouse for BARHL2  
     OriGene qSTAR qPCR primer pairs in human, mouse for BARHL2   OriGene Purified Protein for BARHL2  
     OriGene ORF clones in mouse, rat for BARHL2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for BARHL2   OriGene Custom Protein Services for BARHL2  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BARHL2
     QIAGEN SeqTarget long-range PCR primers for resequencing BARHL2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BARHL2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BARHL2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BARHL2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BARHL2
     GenScript Custom Purified and Recombinant Proteins Services for BARHL2 GenScript cDNA clones with any tag delivered in your preferred vector for BARHL2
     GenScript Custom Assay Services for BARHL2 GenScript Custom Superior Antibodies Services for BARHL2
     GenScript Custom overexpressing Cell Line Services for BARHL2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in BARHL2 promoter
     Search Chromatin IP Primers for BARHL2
     RT2 qPCR Primer Assay in human, mouse, rat BARHL2
     Search GNC Networks for BARHL2
     SABiosciences Custom PCR Arrays for BARHL2
     Search Tocris compounds for BARHL2 (BARH2)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     BARHL2 antibodies
     BARHL2 proteins
     BARHL2 lysates
     Antibodies for BARHL2
     See all of Abcam's Antibodies, Kits and Proteins for BARHL2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for BARHL2
     Antibodies for BARHL2
     ELISAs for BARHL2
     CLIAs for BARHL2
     Search LifeMap BioReagents cell lines for BARHL2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BARHL2
     SwitchGear 3'UTR luciferase reporter plasmids for BARHL2
     SwitchGear Promoter luciferase reporter plasmids for BARHL2
     ThermoFisher Antibodies for BARHL2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BARHL2
     inGenious Targeting Laboratory - Custom generated mouse model solutions for BARHL2
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for BARHL2
    Customized:
     lentivirus for stable overexpression of BARHL2
     lentivirus expression plasmids for stable overexpression of BARHL2
     adenovirus for overexpression of BARHL2
     LSBio Antibodies in human, mouse, rat for BARHL2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      BARHL2 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4