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BAP1 Gene

protein-coding GIFtS: 66

GC03M052410

BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
DKFZp686N04275 ^²
EC 3.4.19.12 ^³
FLJ35406 ^²
FLJ37180 ^²
HUCEP-13 ^²
KIAA0272 ^¹, ², ³
UCHL2 ^¹, ²
hucep-6 ^¹, ²

Descriptions
BRCA1 associated protein-1 ^²
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) ^²
BRCA1-associated protein 1 ^³
Cerebral protein 6 ^³
cerebral protein-13 ^²
cerebral protein-6 ^²
ubiquitin carboxy-terminal hydrolase ^²

External Ids
HGNC: 950¹
Entrez Gene: 8314²
UniProtKB: Q92560³
Ensembl: ENSG00000163930⁷

Search outside databases for aliases for BAP1 gene

Previous GC identifers: GC03M051527 GC03M051687 GC03M052290 GC03M052393

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for BAP1:

The protein encoded by this gene localizes to the nucleus and it interacts with the RING finger

domain of the breast cancer 1, early onset protein (BRCA1). This gene is thought to be a tumor

suppressor gene that functions in the BRCA1 growth control pathway. There are multiple

polyadenylation sites found in this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: BAP1_HUMAN, Q92560

Function: Deubiquitinating enzyme which may be involved in BRCA1 signal transduction pathway

Gene Wiki entry for BAP1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the BAP1 gene

Entrez Gene cytogenetic band: 3p21.31-p21.2 Ensembl cytogenetic band: 3p21.1 HGNC cytogenetic band: 3p21.31-p21.2

BAP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03M052410: (about GC identifiers)

Start:	52,410,064 bp from pter
End:	52,419,058 bp from pter
Size:	8,995 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000003.10 NT_022517.17

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: BAP1_HUMAN, Q92560 (See protein sequence)

Recommended Name: Ubiquitin carboxyl-terminal hydrolase BAP1

Size: 729 amino acids; 80362 Da

Subunit: Interacts with the RING finger domain of BRCA1

Subcellular location: Nucleus

Secondary accessions: Q6LEM0 Q7Z5E8

Post-translational modifications:

Phosphorylated upon DNA damage, probably by ATM or ATR¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_004647.1

ENSEMBL proteins:

ENSP00000296288

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Enzo Life Sciences proteins for BAP1
	Recombinant Proteins from Abcam (BAP1)
	Human Recombinant Proteins from Abnova (BAP1)

OriGene Purified Recombinant Human Protein: BAP1

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0005634	nucleus	TAS	9528852

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Antibodies for BAP1:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of BAP1
	Sigma-Aldrich Antibody Arrays and Antibodies for BAP1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (BAP1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (BAP1)
	Novus Biologicals Antibodies for BAP1

Assays for BAP1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q92560

ProtoNet protein and cluster: Q92560

1 Blocks protein family: IPB001578 Ubiquitin carboxyl-terminal hydrolase

UniProtKB/Swiss-Prot: BAP1_HUMAN, Q92560

Similarity: Belongs to the peptidase C12 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (BAP1)
		Millipore RNAi Products for the Analysis of BAP1 Gene knock-down
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004656

Applied Biosystems Silencer® siRNAs for BAP1

Sigma-Aldrich siRNA and siRNA Panels for BAP1

Sigma-Aldrich shRNA Panels and shRNA for BAP1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for BAP1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_004656
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004656
untagged cDNA clones in CMV expression vector (see all 3): NM_004656

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004656

UniProtKB/Swiss-Prot: BAP1_HUMAN, Q92560

Function: Deubiquitinating enzyme which may be involved in BRCA1 signal transduction pathway

Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide

bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an

intracellular targeting signal)

Enzyme Number (IUBMB): EC 3.4.19.12

Genatlas biochemistry entry for BAP1:

BRCA1 associated protein 1,widely expressed,binding to the BRCA1 RING finger domain and enhancing

BRCA1-mediated cell growth suppression

1 MGI phenotypic allele

for Bap1 (no phenotypes)

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004221	ubiquitin thiolesterase activity	IEA	--
GO:0005515	protein binding	IPI	9528852
GO:0008233	peptidase activity	NAS	9528852
GO:0008234	cysteine-type peptidase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for BAP1 (Your Favorite Gene powered by Ingenuity)

Protein Ubiquitination Pathway

GeneDecks BAP1 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for BAP1

1 Interacting protein for BAP1 (ENSP00000296288³ Q92560¹) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
BRCA1	P38398¹	STRING (score=.752) EBI-1791447, EBI-349905

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006464	protein modification process	NAS	9528852
GO:0006511	ubiquitin-dependent protein catabolic process	IEA	--
GO:0008285	negative regulation of cell proliferation	TAS	9528852

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for BAP1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (BAP1)
		Millipore RNAi Products for the Analysis of BAP1 Gene knock-down
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004656

Sigma-Aldrich siRNA and siRNA Panels for BAP1

Sigma-Aldrich shRNA Panels and shRNA for BAP1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004656

REFSEQ mRNAs for BAP1 gene:

NM_004656.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_004656

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004656
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_004656
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_004656

Additional cDNA sequence:

AB002534.1 AF045581.1 AK092725.1 AK094499.1 AK225494.1 AK292608.1 AK295395.1 AK307274.1

AY130008.1 BC001596.1 BX647318.1 D87462.2 D88812.1

18 DOTS entries:

DT.217303 DT.91763316 DT.102820838 DT.100795050 DT.100795049 DT.120914317 DT.120914340 DT.120914236

DT.100032503 DT.120914364 DT.86854177 DT.97791879 DT.100029516 DT.100795048 DT.102820839 DT.120914363

DT.120914282 DT.80100384

24/369 AceView cDNA sequences (see all 369 ):

BU846231 BX508658 AI963987 Z45707 BE713073 AI917782 BU145192 CK430805

BE535499 AI675206 BM451889 BQ941857 AI401328 AA742202 BQ058097 BM556538

BQ955178 BQ217330 BC001596 BE464104 Z41371 BF196085 AU125284 BX500239

highest scoring ESTs for BAP1:

AF045581 BC001596 BE207318 BE277104 BE730762 BE736910 BF309296 BF966464 BF967313 BG036825

Unigene Cluster for BAP1:

BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

Hs.106674 [show with all ESTs]

Unigene Representative Sequence: NM_004656

GeneLoc Exon Structure

5/13 Alternative Splicing Database (ASD) splice patterns (SP) for BAP1 (see all 13 )

ExUns:	1	^	2	^	3	^	4	^	5	^	6a	·	6b	^	7a	·	7b	·	7c	^	8a	·	8b	^	9	^	10a	·	10b	^	11a	·	11b	·	11c	^	12	^	13	^	14a	·	14b	^	15	^	16	^	17	^	18a	·
SP1:																	-		-		-						-				-																		-
SP2:											-		-
SP3:																																																	-
SP4:									-
SP5:					-

ExUns:	18b	·	18c	^	19	^	20a	·	20b	·	20c	·	20d	·	20e
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for BAP1

1 Ensembl transcript including schematic representation:

ENST00000296288

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

BAP1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for BAP1

¹ / ² / ³

4 probe-sets matching BAP1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
38682_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	AF045581	1.00	1.00	1.00	1
201419_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_004656	0.60	1.00	0.82	1
201419_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1555735_a_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks BAP1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GCCTCTGCCA

SOURCE GeneReport for Unigene cluster: Hs.106674
Expression variation in blood from EXPOLDB for BAP1
UniProtKB/Swiss-Prot: BAP1_HUMAN, Q92560
Tissue specificity: Highly expressed in testis, placenta and ovary. Expressed in breast

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for BAP1 gene from 5/10 species (see all 10 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	BAP1¹	--	BRCA1 associated protein-1 (ubiquitin carboxy-terminal more	90.77(n) 94.63(a)	484737 XM_854401.1 XP_859494.1
chimpanzee (Pan troglodytes)	BAP1¹	--	BRCA1 associated protein-1 (ubiquitin carboxy-terminal more	99.54(n) 99.73(a)	460426 XM_001171970.1 XP_001171970.1
rat (Rattus norvegicus)	Bap1¹	--	BRCA1 associated protein-1 (ubiquitin carboxy-terminal more	89.27(n) 93.95(a)	306257 XM_224614.4 XP_224614.4
mouse (Mus musculus)	Bap1^{1, 5}	14⁵	Brca1 associated protein 1^{1, 5}	88.64(n)¹ 93.54(a)¹	104416¹ NM_027088.2¹ NP_081364.1¹ AA989761⁵ AB047820⁵ (see all 26)
chicken (Gallus gallus)	BAP1¹	--	BRCA1 associated protein-1 (ubiquitin carboxy-terminal more	80.83(n) 85.55(a)	415944 NM_001030590.1 NP_001025761.1

About this table Species with no ortholog for BAP1

ENSEMBL Gene Tree for BAP1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for BAP1 gene

UCHL5²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/46 NCBI SNPs in BAP1 are shown (see all 46 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 42)

AB	SNP ID	Valid	Chr 3 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs123598^1,2	A,C,F,H	52410900(+)	`AGTTGG/AGACCG`	1	--	ut3¹ ese³		10	EA NA EU WA	872
	rs35353781^1,2	C,F	52412237(+)	`GCCTCA/TCCATC`	1	V/E	mis¹		5	NA EU EA WA	446
	rs9855479^1,2	F,H	52410370(+)	`ACCCTG/AAGTGC`	1	--	ut3¹ ese³		4	EU EA WA	410
	rs34736117^1,2	F	52412788(+)	`CTCCCA/CGCCCC`	1	A/A	syn¹		1	NA	46
	rs123602^1,2	A,C,F,H,O	52417394(+)	`AGTTCG/CTTCTG`	1	--	int¹		10	EA MN EU WA NA	2343
	rs9842960^1,2	A,F,H	52413308(+)	`GCTTAC/TGTGCT`	1	--	int¹		4	EU EA WA	410
	rs419604^1,2	C,F,H	52416646(+)	`TTCTTA/TAAAGG`	1	--	int¹		8	EU EA WA	838
	rs3821840^1,2	F,H	52417245(-)	`AGAAGG/AGGAGT`	1	--	int¹ trp³		4	EA EU	1758
	rs9848628^1,2	C,H	52414487(+)	`AAGCTC/TTAAGT`	1	--	int¹		4	EU EA WA	410
	rs9848343^1,2	H	52414351(+)	`ACCATC/TTGAGA`	1	--	int¹ spl³		4	EU EA WA	420

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HapMap Linkage Disequilibrium images for BAP1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 603089

UniProtKB/Swiss-Prot: BAP1_HUMAN, Q92560

Defects in BAP1 are found in non-small cell lung cancer (NSCLC) cell lines

Tumor-associated antigen found in several childhood medulloblastoma

3 Novoseek disease relationships for BAP1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
parkinson disease	36.72	2	12775255 (1), 10203348 (1)
breast cancer	20.08	4	9528852 (2), 19197335 (1)
tumors	0.00	2	12800201 (1), 9528852 (1)

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Human Genome Epidemiology Navigator: BAP1 (4 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/32 PubMed articles for BAP1 gene (see all 32 ):

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression. (PubMed id 9528852)^{1, 2, 3, 4} Jensen D.E.... Rauscher F.J. III (1998)
Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries. (PubMed id 12800201)^{1, 3, 4} Behrends U.... Mautner J. (2003)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)^{3, 4} Beausoleil S.A....Gygi S.P. (2004)
Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)^{3, 4} Nakajima D.... Nagase T. (2002)
Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)^{3, 4} Nagase T....Nomura N. (1996)
BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity. (PubMed id 19117993)^{1, 3} Nishikawa H....Ohta T. (2009)
Genetic sequence variations of BRCA1-interacting genes AURKA, BAP1, BARD1 and DHX9 in French Canadian Families with high risk of breast cancer. (PubMed id 19197335)^{1, 3} GuAcnard F....Durocher F. (2009)
Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population. (PubMed id 19367581)³ So H.C....Sham P.C. (2009)
Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study. (PubMed id 18950845)³ Vega A....Carracedo A. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 8314	HGNC: 950	AceView: BAP1	Ensembl:ENSG00000163930	euGenes: HUgn8314
ECgene: BAP1	H-InvDB: BAP1

(According to HUGE)
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HUGE: KIAA0272

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for BAP1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for BAP1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for BAP1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for BAP1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for BAP1		Antibodies for BAP1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for BAP1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (BAP1)
	Antibodies (BAP1)
	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (BAP1)
	Antibodies (BAP1)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for BAP1

	Proteins for BAP1
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for BAP1

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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BAP1 Gene at Home site.
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BAP1 Gene

protein-coding GIFtS: 66

Aliases &
Descriptions
for BAP1

Summaries
for BAP1

Genomic Location
for BAP1

Proteins
for BAP1

Protein Domains/
Families
for BAP1

Gene Function
for BAP1

Pathways & Interactions
for BAP1

Drugs & Compounds
for BAP1

Transcripts
for BAP1

Expression
for BAP1

Orthologs
for BAP1

Paralogs
for BAP1

SNPs/Variants
for BAP1

Disorders & Mutations
for BAP1

Medical News
for BAP1

Publications
for BAP1

Search for BAP1

Genome Databases showing BAP1

Other Databases showing BAP1

Specialized Databases showing BAP1

Licensable Technologies
for BAP1

Services
for BAP1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

BAP1 Gene

protein-coding GIFtS: 66

Aliases & Descriptionsfor BAP1

Summariesfor BAP1

Genomic Locationfor BAP1

Proteinsfor BAP1

Protein Domains/Familiesfor BAP1

Gene Functionfor BAP1

Pathways & Interactionsfor BAP1

Drugs & Compoundsfor BAP1

Transcriptsfor BAP1

Expression for BAP1

Orthologsfor BAP1

Paralogsfor BAP1

SNPs/Variantsfor BAP1

Disorders & Mutationsfor BAP1

Medical Newsfor BAP1

Publicationsfor BAP1

Search for BAP1

Genome Databases showing BAP1

Other Databases showing BAP1

Specialized Databases showing BAP1

Licensable Technologiesfor BAP1

Servicesfor BAP1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for BAP1

Summaries
for BAP1

Genomic Location
for BAP1

Proteins
for BAP1

Protein Domains/
Families
for BAP1

Gene Function
for BAP1

Pathways & Interactions
for BAP1

Drugs & Compounds
for BAP1

Transcripts
for BAP1

Expression
for BAP1

Orthologs
for BAP1

Paralogs
for BAP1

SNPs/Variants
for BAP1

Disorders & Mutations
for BAP1

Medical News
for BAP1

Publications
for BAP1

Licensable Technologies
for BAP1

Services
for BAP1