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BANP Gene

protein-coding   GIFtS: 52
GCID: GC16P087984

BTG3 Associated Nuclear Protein

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
BTG3 Associated Nuclear Protein1 2     BEN Domain Containing 11
SMAR12 3 5     SMARBP12
Scaffold/Matrix-Associated Region-1-Binding Protein2 3     Protein BANP2
BEND12 3     Btg3-Associated Nuclear Protein3
BEN Domain-Containing Protein 12 3     

External Ids:    HGNC: 134501   Entrez Gene: 549712   Ensembl: ENSG000001725307   OMIM: 6115645   UniProtKB: Q8N9N53   

Export aliases for BANP gene to outside databases

Previous GC identifers: GC18M011860 GC16P089015 GC16P087725 GC16P087766 GC16P086542 GC16P073724


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BANP Gene:
This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and
negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple
transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Mar 2010)

GeneCards Summary for BANP Gene:
BANP (BTG3 associated nuclear protein) is a protein-coding gene. Diseases associated with BANP include keratoconus, and blindness. GO annotations related to this gene include p53 binding.

UniProtKB/Swiss-Prot: BANP_HUMAN, Q8N9N5
Function: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer
function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream
of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby
diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation,
which causes cell cycle arrest (By similarity)

Gene Wiki entry for BANP Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000016.10  NT_010498.16  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the BANP gene promoter:
         p53   AP-1   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBANP promoter sequence
   Search Chromatin IP Primers for BANP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BANP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q24   Ensembl cytogenetic band:  16q24.2   HGNC cytogenetic band: 16q24

BANP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BANP gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P087984:  view genomic region     (about GC identifiers)

Start:
87,982,850 bp from pter      End:
88,110,924 bp from pter
Size:
128,075 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: BANP_HUMAN, Q8N9N5 (See protein sequence)
Recommended Name: Protein BANP  
Size: 519 amino acids; 56494 Da
Subunit: Interacts with TP53 and CUX1/CDP (By similarity). Interacts with HDAC1. Part of a corepressor complex
containing BANP, HDAC1, SIN3A, SIN3B, RBL1 and RBL2
Sequence caution: Sequence=BAC04296.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A8MU25 A8MX25 B2RCF7 B4DNJ9 F5GZM0 Q96GJ7 Q9NWY1
Alternative splicing: 7 isoforms:  Q8N9N5-1   Q8N9N5-2   Q8N9N5-3   Q8N9N5-4   Q8N9N5-5   Q8N9N5-6   Q8N9N5-7   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BANP: NX_Q8N9N5

Explore proteomics data for BANP at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See BANP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (7 alternative transcripts): 
    NP_001167010.1  NP_001167011.1  NP_001167012.1  NP_001167013.1  NP_001167014.1  NP_060339.2  NP_524576.2  

    ENSEMBL proteins: 
     ENSP00000401718   ENSP00000411479   ENSP00000413717   ENSP00000432508   ENSP00000376903  
     ENSP00000435727   ENSP00000390504   ENSP00000436869   ENSP00000431812   ENSP00000347125  
     ENSP00000399576   ENSP00000401454   ENSP00000410089   ENSP00000376902   ENSP00000286122  
     ENSP00000347290   ENSP00000444352  

    BANP Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for BANP
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    Novus Biologicals BANP Proteins
    Novus Biologicals BANP Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for BANP

    BANP Antibody Products:

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    Abcam antibodies for BANP
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    BANP Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for BANP
    Cloud-Clone Corp. CLIAs for BANP


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    BEND: BEN domain containing

    1 InterPro protein domain:
     IPR018379 BEN_domain

    Graphical View of Domain Structure for InterPro Entry Q8N9N5

    ProtoNet protein and cluster: Q8N9N5

    UniProtKB/Swiss-Prot: BANP_HUMAN, Q8N9N5
    Similarity: Belongs to the BANP/SMAR1 family
    Similarity: Contains 1 BEN domain


    BANP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BANP_HUMAN, Q8N9N5
    Function: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer
    function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream
    of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby
    diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation,
    which causes cell cycle arrest (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002039p53 binding IEA--
    GO:0003677DNA binding IEA--
    GO:0005515protein binding IPI--
         
    BANP for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BANP
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BANP
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for BANP

    miRNA
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    Block miRNA regulation of human, mouse, rat BANP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BANP (see all 14):
    hsa-miR-21* hsa-miR-320a hsa-miR-148b* hsa-miR-548p hsa-miR-526b hsa-miR-3120-3p hsa-miR-320d hsa-miR-545
    SwitchGear 3'UTR luciferase reporter plasmidBANP 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat BANP

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for BANP (see all 39)
    OriGene ORF clones in mouse, rat for BANP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 7): BANP (NM_017869)
    Sino Biological Human cDNA Clone for BANP
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BANP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BANP

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BANP


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BANP_HUMAN, Q8N9N5: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytoskeleton2
    cytosol2
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    BANP for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BANP
    Interactions:

        GeneGlobe Interaction Network for BANP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    Selected Interacting proteins for BANP (Q8N9N51, 2, 3 ENSP000003769034) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TP53P046371, 2, 3, ENSP000002693054EBI-744695,EBI-366083 MINT-7893049 MINT-7893107 MINT-7893094 I2D: score=3 STRING: ENSP00000269305
    PMLP295902, 3, ENSP000002680584MINT-7893141 MINT-7893127 MINT-7893117 I2D: score=2 STRING: ENSP00000268058
    ENSG00000229353P221053I2D: score=1 
    ENSG00000236236P221053I2D: score=1 
    TNXBP221053I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0007049cell cycle IEA--
    GO:0007275multicellular organismal development IEA--
    GO:0016568chromatin modification IEA--

    BANP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BANP



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for BANP gene (7 alternative transcripts): 
    NM_001173539.1  NM_001173540.1  NM_001173541.1  NM_001173542.1  NM_001173543.1  NM_017869.3  NM_079837.2  

    Unigene Cluster for BANP:

    BTG3 associated nuclear protein
    Hs.461705  [show with all ESTs]
    Unigene Representative Sequence: NM_001173543
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 26):
    ENST00000569400 ENST00000423252 ENST00000488074 ENST00000439677 ENST00000454563
    ENST00000479780 ENST00000393208(uc002fkp.3 uc002fkq.3 uc002fks.4)
    ENST00000459966 ENST00000412691 ENST00000526460 ENST00000485772 ENST00000466197
    ENST00000355022 ENST00000436970 ENST00000436274 ENST00000456902 ENST00000393207(uc002fkr.3)
    ENST00000474563
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate BANP (see all 14):
    hsa-miR-21* hsa-miR-320a hsa-miR-148b* hsa-miR-548p hsa-miR-526b hsa-miR-3120-3p hsa-miR-320d hsa-miR-545
    SwitchGear 3'UTR luciferase reporter plasmidBANP 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat BANP
    Clone
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    OriGene ORF clones in mouse, rat for BANP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 7): BANP (NM_017869)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BANP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BANP
    Primer
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    OriGene qPCR primer pairs and template standards for BANP
    OriGene qSTAR qPCR primer pairs in human, mouse for BANP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BANP
      QuantiTect SYBR Green Assays in human, mouse, rat BANP
      QuantiFast Probe-based Assays in human, mouse, rat BANP

    Additional mRNA sequence: 

    AK001039.1 AK094158.1 AK125232.1 AK293472.1 AK297945.1 AK315089.1 AK315535.1 BC009424.1 
    BC018247.1 

    24 DOTS entries:

    DT.92425420  DT.100706645  DT.95098443  DT.95378441  DT.451949  DT.120686119  DT.100832434  DT.91817711 
    DT.95275274  DT.95295952  DT.120686201  DT.120686143  DT.95227137  DT.95275276  DT.100688898  DT.120686137 
    DT.100761656  DT.100780216  DT.100780217  DT.100832432  DT.102829785  DT.100740200  DT.120686187  DT.95153065 

    Selected AceView cDNA sequences (see all 125):

    BQ949742 NM_017869 BM839530 BX360845 BX950991 BE018428 NM_079837 CD673246 
    AA902510 BE297226 BE887471 AL549677 BM800774 CD628690 CN478761 BQ646135 
    CB216683 BQ677433 AW131241 BI768826 BI769850 CB961560 BX360844 AU118660 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for BANP (see all 11)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^
    SP1:              -     -     -     -     -     -                       -     -     -     -     -     -     -     -     -                                       
    SP2:                                                                                            -                                                               
    SP3:                                      -     -           -                                                                                                   
    SP4:                                -     -     -           -                                   -     -     -                                                   
    SP5:                                                        -                                                                                                   

    ExUns: 17 ^ 18
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for BANP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BANP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGCAGGTGT
    BANP Expression
    About this image


    BANP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
    BANP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BANP Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.461705

    UniProtKB/Swiss-Prot: BANP_HUMAN, Q8N9N5
    Tissue specificity: Down-regulated in breast cancer cell lines

        Custom PCR Arrays for BANP
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    QuantiTect SYBR Green Assays in human, mouse, rat BANP
    QuantiFast Probe-based Assays in human, mouse, rat BANP
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BANP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for BANP gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Banp1 , 5 BTG3 associated nuclear protein1, 5 88.08(n)1
    96.25(a)1
      8 (70.82 cM)5
    533251  NM_016812.41  NP_058092.21 
     1219497505 
    chicken
    (Gallus gallus)
    Aves BANP1 BTG3 associated nuclear protein 78.42(n)
    87.52(a)
      415834  NM_001173545.1  NP_001167016.1 
    lizard
    (Anolis carolinensis)
    Reptilia BANP6
    BTG3 associated nuclear protein
    79(a)
    1 ↔ 1
    GL343689.1(18114-115251)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.161982 Xenopus laevis transcribed sequence with weak similarity more 76.33(n)    BU914297.1 
    zebrafish
    (Danio rerio)
    Actinopterygii banp1 BTG3 associated nuclear protein 70.1(n)
    74.28(a)
      553659  NM_001020632.1  NP_001018468.1 


    ENSEMBL Gene Tree for BANP (if available)
    TreeFam Gene Tree for BANP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BANP gene
    1 SIMAP similar gene for BANP using alignment to 11 protein entries:     BANP_HUMAN (see all proteins):
    DKFZp761H172

    BANP for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for BANP
    PGOHUM00000249039


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BANP (see all 3971)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs713836821,2
    --73795951(+) TTGTGC/GTGCCT 7 -- int11Minor allele frequency- G:0.00NA 2
    rs72007291,2
    C,F,H--87983055(+) CTGTGG/TCAGCT 5 -- us2k123Minor allele frequency- T:0.12NS EA NA WA CSA 2118
    rs1411034851,2
    --87983111(+) AGCAAA/GGCGCT 5 -- us2k10--------
    rs1449170241,2
    --87983148(+) CTCTCC/TAGCCC 5 -- us2k10--------
    rs1825630651,2
    --87983280(+) TGGAGC/TGTTTG 5 -- us2k10--------
    rs1408881551,2
    C--87983332(+) GTGGA-/ACCTCCAAGCCTAA
    TTCTGGAGGAGACTTT
    AACTC
    5 -- us2k10--------
    rs1871156651,2
    --87983336(+) AACCTC/TCAAGC 5 -- us2k10--------
    rs1385752911,2
    --87983493(+) TTTTTC/TTTTTT 5 -- us2k10--------
    rs1915479321,2
    --87983590(+) GCCATG/TCTCCC 5 -- us2k10--------
    rs1488692701,2
    --87983624(+) GACTAC/TAGGCG 5 -- us2k10--------

    HapMap Linkage Disequilibrium report for BANP (87982850 - 88110924 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for BANP (see all 31):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2714948CNV Deletion23290073
    esv1227822CNV Deletion17803354
    esv2714946CNV Deletion23290073
    esv2714954CNV Deletion23290073
    esv2672889CNV Deletion23128226
    esv2714947CNV Deletion23290073
    esv2714953CNV Deletion23290073
    esv2714949CNV Deletion23290073
    esv997568CNV Deletion20482838
    esv2714952CNV Deletion23290073

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 611564    OMIM disorders: --

    4 diseases for BANP:    
    About MalaCards
    keratoconus    blindness    hiv-1    breast cancer


    BANP for disorders           About GeneDecksing

    Genetic Association Database (GAD): BANP
    Human Genome Epidemiology (HuGE) Navigator: BANP (1 document)

    Export disorders for BANP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for BANP gene, integrated from 10 sources (see all 38):
    (articles sorted by number of sources associating them with BANP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and molecular analysis of BANP. (PubMed id 10940556)1, 2, 3, 9 Birot A.-M.... Rouault J.-P. (Gene 2000)
    2. New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8. (PubMed id 20719862)1, 4 Vitart V....Wright A. (Hum. Mol. Genet. 2010)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Loci at chromosomes 13, 19 and 20 influence age at natural menopause. (PubMed id 19448619)1, 4 Stolk L....Uitterlinden A.G. (Nat. Genet. 2009)
    5. Tumor suppressor SMAR1 mediates cyclin D1 repression by recruitment of the SIN3/histone deacetylase 1 complex. (PubMed id 16166625)1, 2 Rampalli S.... Chattopadhyay S. (Mol. Cell. Biol. 2005)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. SMAR1, a novel, alternatively spliced gene product, binds the Scaffold/Matrix-associated region at the T cell receptor beta locus. (PubMed id 10950932)1, 3 Chattopadhyay S....Chen J. (Genomics 2000)
    8. SMAR1 forms a ternary complex with p53-MDM2 and negatively regulates p53-mediated transcription. (PubMed id 19303885)1, 9 Pavithra L....Chattopadhyay S. (J. Mol. Biol. 2009)
    9. Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (J. Proteome Res. 2013)
    10. Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. (PubMed id 23291589)1 Lu Y....Wong T.Y. (Nat. Genet. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 54971 HGNC: 13450 AceView: BANP Ensembl:ENSG00000172530 euGenes: HUgn54971
    ECgene: BANP H-InvDB: BANP

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for BANP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for BANP gene:
    Search GeneIP for patents involving BANP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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