Aliases for BANK1 Gene
External Ids for BANK1 Gene
Previous GeneCards Identifiers for BANK1 Gene
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
GeneCards Summary for BANK1 Gene
BANK1 (B-Cell Scaffold Protein With Ankyrin Repeats 1) is a Protein Coding gene. Diseases associated with BANK1 include Multifocal Motor Neuropathy and Diffuse Cutaneous Systemic Sclerosis. An important paralog of this gene is PIK3AP1.
UniProtKB/Swiss-Prot for BANK1 Gene
Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2.