Aliases for BANF2 Gene
Aliases for BANF2 Gene
External Ids for BANF2 Gene
- HGNC: 16172
- Entrez Gene: 140836
- Ensembl: ENSG00000125888
- UniProtKB: Q9H503
Previous HGNC Symbols for BANF2 Gene
- C20orf179
Previous GeneCards Identifiers for BANF2 Gene
- GC20P017630
Summaries for BANF2 Gene
GeneCards Summary for BANF2 Gene
BANF2 (Barrier To Autointegration Factor 2) is a Protein Coding gene. An important paralog of this gene is BANF1.
UniProtKB/Swiss-Prot for BANF2 Gene
-
May play a role in BANF1 regulation and influence tissue-specific roles of BANF1.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BANF2 Gene
Genomics for BANF2 Gene
Regulatory Elements for BANF2 Gene
Enhancers for BANF2 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around BANF2 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the BANF2 gene promoter:
Regulatory Element Products
Genomic Location for BANF2 Gene
- Chromosome:
- 20
- Start:
- 17,693,672 bp from pter
- End:
- 17,735,872 bp from pter
- Size:
- 42,201 bases
- Orientation:
- Plus strand
Genomic View for BANF2 Gene
Genes around BANF2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 20p12.1 by Ensembl
- 20p12.1 by Entrez Gene
- 20p12.1 by HGNC
BANF2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for BANF2 Gene
Proteins for BANF2 Gene
-
Protein details for BANF2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H503-BAFL_HUMAN
- Recommended name:
- Barrier-to-autointegration factor-like protein
- Protein Accession:
- Q9H503
- D3DW25
- F5H3F6
- Q7Z4M6
Protein attributes for BANF2 Gene
- Size:
- 90 amino acids
- Molecular mass:
- 10309 Da
- Quaternary structure:
-
- Homodimer. Heterodimerizes with BANF1.
Protein Expression for BANF2 Gene
Post-translational modifications for BANF2 Gene
Other Protein References for BANF2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for BANF2
- Invitrogen Antibodies for BANF2
- GeneTex Il17ra antibody for BANF2
Protein Products
-
OriGene Purified Proteins for BANF2
- Search Origene for MassSpec and Protein Over-expression Lysates for BANF2
- Origene Custom Protein Services for BANF2
- antibodies-online Proteins for BANF2: See all 6
- Search antibodies-online for peptides
- Search GeneTex for Proteins for BANF2
Assay Products
No data available for DME Specific Peptides for BANF2 Gene
Domains & Families for BANF2 Gene
Protein Domains for BANF2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for BANF2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9H503- Family:
-
- Belongs to the BAF family.
No data available for Gene Families for BANF2 Gene
Function for BANF2 Gene
Molecular function for BANF2 Gene
- UniProtKB/Swiss-Prot Function:
- May play a role in BANF1 regulation and influence tissue-specific roles of BANF1.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
Phenotypes for BANF2 Gene
- GenomeRNAi human phenotypes for BANF2:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for BANF2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for BANF2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for BANF2 gene
- Search ViGene Biosciences for BANF2
CRISPR Products
-
OriGene CRISPR knockouts for BANF2
-
Santa Cruz Biotechnology (SCBT) CRISPR for BANF2
- GenScript: Design CRISPR guide RNA sequences for BANF2
miRNA Products
- Search ViGene Biosciences for BANF2
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for BANF2
- Browse OriGene Inhibitory RNA Products For BANF2
-
ViGene Biosciences ready-to-package AAV shRNAs for BANF2 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for BANF2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BANF2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for BANF2
-
ViGene Biosciences adenoviral particle packaged cDNA for BANF2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for BANF2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for BANF2 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BANF2 Gene
Localization for BANF2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for BANF2 Gene
- Nucleus. Cytoplasm.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 2 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA,IDA | 21630459 |
| GO:0005737 | cytoplasm | IEA | -- |
Pathways & Interactions for BANF2 Gene
No Data Available
Interacting Proteins for BANF2 Gene
No data available for Pathways by source and SIGNOR curated interactions for BANF2 Gene
Transcripts for BANF2 Gene
mRNA/cDNA for BANF2 Gene
- (6) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (19) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for BANF2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for BANF2
-
Santa Cruz Biotechnology (SCBT) CRISPR for BANF2
- GenScript: Design CRISPR guide RNA sequences for BANF2
miRNA Products
- Search ViGene Biosciences for BANF2
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for BANF2
- Browse OriGene Inhibitory RNA Products For BANF2
-
ViGene Biosciences ready-to-package AAV shRNAs for BANF2 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for BANF2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BANF2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||
| SP2: | - | - | |||||||||||
| SP3: |
Expression for BANF2 Gene
mRNA differential expression in normal tissues according to GTEx for BANF2 Gene
This gene is overexpressed in Testis (x50.7).
This gene is overexpressed in Testis (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for BANF2 Gene
NURSA nuclear receptor signaling pathways regulating expression of BANF2 Gene:
BANF2SOURCE GeneReport for Unigene cluster for BANF2 Gene:
Hs.115366mRNA Expression by UniProt/SwissProt for BANF2 Gene:
Q9H503-BAFL_HUMAN
Tissue specificity:
Expressed strongly in testis and pancreas. Also detected in brain, colon, liver, lung, ovary, placenta, prostate, small intestine, spleen and thymus. Not detected in heart, kidney and skeletal muscle.
Primer Products
-
OriGene qPCR primer pairs for BANF2
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BANF2 Gene
Orthologs for BANF2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | BANF2 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | BANF2 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Banf2 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Banf2 34 16 35 |
|
||
| cow (Bos Taurus) |
Mammalia | BANF2 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | BANF2 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | BANF2 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | si:dkey-211g8.4 35 |
|
ManyToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | baf-1 35 |
|
OneToOne |
- Species where no ortholog for BANF2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for BANF2 Gene
(1) SIMAP similar genes for BANF2 Gene using alignment to 2 proteins:
Variants for BANF2 Gene
| SNP ID | Clin | Chr 20 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000073854 | -- | 17,716,334(+) | CTTCT(C/T)TTCTT | intron-variant | |
| rs1000164618 | -- | 17,692,663(+) | CCCAG(C/T)GTGGA | upstream-variant-2KB | |
| rs1000232907 | -- | 17,695,025(+) | GTCAT(A/T)AAACG | intron-variant | |
| rs1000328598 | -- | 17,723,356(+) | GCTTG(C/T)AAAGG | intron-variant | |
| rs1000418175 | -- | 17,704,133(+) | AGGGC(A/G)AGAGC | intron-variant |
Residual Variation Intolerance Score:
60.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
9.97;
89.93% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for BANF2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- BANF2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for BANF2 Gene
Disorders for BANF2 Gene
Relevant External Links for BANF2
No disorders were found for BANF2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BANF2 Gene
Publications for BANF2 Gene
- Barrier-to-autointegration factor-like (BAF-L): a proposed regulator of BAF. (PMID: 16337940) Tifft K.E. … Wilson K.L. (Exp. Cell Res. 2006) 3 4 22 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4 64
- Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. (PMID: 7829101) Robertson N.G. … Morton C.C. (Genomics 1994) 3 4 64
Products for BANF2 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for BANF2
- Search Origene for MassSpec and Protein Over-expression Lysates for BANF2
- Origene Custom Protein Services for BANF2
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for BANF2
- Browse OriGene Inhibitory RNA Products For BANF2
- OriGene qPCR primer pairs for BANF2
- OriGene CRISPR knockouts for BANF2
- OriGene ORF clones in human for BANF2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For BANF2
- GenScript: Next-day shipping cDNA ORF clone for BANF2 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for BANF2
- GenScript Custom Assay Services for BANF2
- GenScript Custom overexpressing Cell Line Services for BANF2
- GenScript: Design CRISPR guide RNA sequences for BANF2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for BANF2
- Browse Sino Biological cDNA Clones
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- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for BANF2
- Novus Biologicals proteins and lysates for BANF2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for BANF2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for BANF2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for BANF2 gene
- Search ViGene Biosciences for BANF2
- Horizon Cell Lines for BANF2
- Cyagen custom Knockout/knockin (KOKI) mouse models for BANF2
- VectorBuilder custom plasmid, inducible vectors for BANF2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BANF2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for BANF2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer