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Aliases for BANF2 Gene

Aliases for BANF2 Gene

  • Barrier To Autointegration Factor 2 2 3 5
  • Barrier-To-Autointegration Factor 2 3 4
  • C20orf179 3 4
  • BAF-L 3 4
  • BAFL 3 4
  • Testis Secretory Sperm-Binding Protein Li 212a 3
  • Chromosome 20 Open Reading Frame 179 2
  • BAF2 3

External Ids for BANF2 Gene

Previous HGNC Symbols for BANF2 Gene

  • C20orf179

Previous GeneCards Identifiers for BANF2 Gene

  • GC20P017630

Summaries for BANF2 Gene

GeneCards Summary for BANF2 Gene

BANF2 (Barrier To Autointegration Factor 2) is a Protein Coding gene. An important paralog of this gene is BANF1.

UniProtKB/Swiss-Prot for BANF2 Gene

  • May play a role in BANF1 regulation and influence tissue-specific roles of BANF1.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BANF2 Gene

Genomics for BANF2 Gene

Regulatory Elements for BANF2 Gene

Enhancers for BANF2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around BANF2 on UCSC Golden Path with GeneCards custom track

Genomic Location for BANF2 Gene

17,693,672 bp from pter
17,735,872 bp from pter
42,201 bases
Plus strand

Genomic View for BANF2 Gene

Genes around BANF2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BANF2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BANF2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BANF2 Gene

Proteins for BANF2 Gene

  • Protein details for BANF2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Barrier-to-autointegration factor-like protein
    Protein Accession:
    Secondary Accessions:
    • D3DW25
    • F5H3F6
    • Q7Z4M6

    Protein attributes for BANF2 Gene

    90 amino acids
    Molecular mass:
    10309 Da
    Quaternary structure:
    • Homodimer. Heterodimerizes with BANF1.

    Alternative splice isoforms for BANF2 Gene


neXtProt entry for BANF2 Gene

Proteomics data for BANF2 Gene at MOPED

Post-translational modifications for BANF2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for BANF2 Gene

No data available for DME Specific Peptides for BANF2 Gene

Domains & Families for BANF2 Gene

Protein Domains for BANF2 Gene

Suggested Antigen Peptide Sequences for BANF2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the BAF family.
  • Belongs to the BAF family.
genes like me logo Genes that share domains with BANF2: view

No data available for Gene Families for BANF2 Gene

Function for BANF2 Gene

Molecular function for BANF2 Gene

UniProtKB/Swiss-Prot Function:
May play a role in BANF1 regulation and influence tissue-specific roles of BANF1.

Phenotypes for BANF2 Gene

GenomeRNAi human phenotypes for BANF2:
genes like me logo Genes that share phenotypes with BANF2: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BANF2 Gene

Localization for BANF2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BANF2 Gene

Nucleus. Cytoplasm.

Subcellular locations from

Jensen Localization Image for BANF2 Gene COMPARTMENTS Subcellular localization image for BANF2 gene
Compartment Confidence
nucleus 5
cytosol 2
extracellular 2

No data available for Gene Ontology (GO) - Cellular Components for BANF2 Gene

Pathways & Interactions for BANF2 Gene

SuperPathways for BANF2 Gene

No Data Available

Interacting Proteins for BANF2 Gene

Gene Ontology (GO) - Biological Process for BANF2 Gene


No data available for Pathways by source and SIGNOR curated interactions for BANF2 Gene

Drugs & Compounds for BANF2 Gene

No Compound Related Data Available

Transcripts for BANF2 Gene

Unigene Clusters for BANF2 Gene

Barrier to autointegration factor 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for BANF2 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b
SP1: -
SP2: - -

Relevant External Links for BANF2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BANF2 Gene

mRNA expression in normal human tissues for BANF2 Gene

mRNA differential expression in normal tissues according to GTEx for BANF2 Gene

This gene is overexpressed in Testis (x50.7).

Protein differential expression in normal tissues from HIPED for BANF2 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for BANF2 Gene

SOURCE GeneReport for Unigene cluster for BANF2 Gene Hs.115366

mRNA Expression by UniProt/SwissProt for BANF2 Gene

Tissue specificity: Expressed strongly in testis and pancreas. Also detected in brain, colon, liver, lung, ovary, placenta, prostate, small intestine, spleen and thymus. Not detected in heart, kidney and skeletal muscle.
genes like me logo Genes that share expression patterns with BANF2: view

Protein tissue co-expression partners for BANF2 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for BANF2 Gene

Orthologs for BANF2 Gene

This gene was present in the common ancestor of animals.

Orthologs for BANF2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia BANF2 35
  • 84.07 (n)
  • 85.56 (a)
BANF2 36
  • 86 (a)
(Canis familiaris)
Mammalia BANF2 35
  • 88.89 (n)
  • 90 (a)
BANF2 36
  • 90 (a)
(Mus musculus)
Mammalia Banf2 35
  • 85.56 (n)
  • 87.78 (a)
Banf2 16
Banf2 36
  • 88 (a)
(Pan troglodytes)
Mammalia BANF2 35
  • 98.89 (n)
  • 97.78 (a)
BANF2 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Banf2 35
  • 86.23 (n)
  • 88.04 (a)
(Monodelphis domestica)
Mammalia BANF2 36
  • 59 (a)
(Anolis carolinensis)
Reptilia BANF2 36
  • 46 (a)
(Danio rerio)
Actinopterygii si:dkey-211g8.4 36
  • 35 (a)
(Caenorhabditis elegans)
Secernentea baf-1 36
  • 37 (a)
Species with no ortholog for BANF2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for BANF2 Gene

Gene Tree for BANF2 (if available)
Gene Tree for BANF2 (if available)

Paralogs for BANF2 Gene

Paralogs for BANF2 Gene

(1) SIMAP similar genes for BANF2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with BANF2: view

Variants for BANF2 Gene

Sequence variations from dbSNP and Humsavar for BANF2 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1053993 - 17,735,771(+) GCAGA(C/G)TTCTC reference, missense
rs4814640 - 17,725,032(+) TGGAC(A/G)ACATG reference, missense
rs427456 -- 17,715,594(+) GTGGT(C/T)ATTAG intron-variant
rs430163 -- 17,714,067(+) caggc(A/G)tggtg intron-variant
rs434445 -- 17,714,881(+) cccgc(C/T)ctgtg intron-variant

Variation tolerance for BANF2 Gene

Residual Variation Intolerance Score: 60.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.97; 89.93% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for BANF2 Gene

Disorders for BANF2 Gene

Relevant External Links for BANF2

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for BANF2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BANF2 Gene

Publications for BANF2 Gene

  1. Barrier-to-autointegration factor-like (BAF-L): a proposed regulator of BAF. (PMID: 16337940) Tifft K.E. … Wilson K.L. (Exp. Cell Res. 2006) 3 4 23 67
  2. Proteomic characterization of the human sperm nucleus. (PMID: 21630459) de Mateo S. … Oliva R. (Proteomics 2011) 3
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for BANF2 Gene

Sources for BANF2 Gene