BANF2 Gene
protein-coding GIFtS: 43
GCID: GC20P017680
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barrier to autointegration factor 2(Previous name: chromosome 20 open reading frame 179 )
(Previous symbol: C20orf179)
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Aliases
for BANF2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Barrier To Autointegration Factor 21 2 | | Barrier-To-Autointegration Factor 22 3 | | BAF-L1 2 3 | | Chromosome 20 Open Reading Frame 1791 | | BAFL1 2 3 | | DJ803K15.11 | | C20orf1791 2 3 | | Barrier-To-Autointegration Factor-Like Protein2 | | BAF21 2 | | |
Export aliases for BANF2 gene to outside databasesPrevious GC identifer: GC20P017630 |
Summaries
for BANF2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: BAFL_HUMAN, Q9H503Function: May play a role in BANF1 regulation and influence tissue-specific roles of BANF1
|
Genomic Views
for BANF2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011387.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BANF2 gene promoter:
AhR GR AP-1 STAT3 GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for BANF2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BANF2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p12.1 Ensembl cytogenetic band: 20p12.1 HGNC cytogenetic band: 20p12.1BANF2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20P017680: view genomic region
(about GC identifiers)
Start:
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17,674,320 bp from pter |
End:
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17,716,517 bp from pter |
Size:
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42,198 bases |
Orientation:
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plus strand |
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Proteins
for BANF2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BAFL_HUMAN, Q9H503 (See
protein sequence)Recommended Name: Barrier-to-autointegration factor-like protein Size: 90 amino acids; 10309 Da
Subunit: Homodimer. Heterodimerizes with BANF1
Subcellular location: Nucleus. Cytoplasm
Caution: In contrast to BANF1, it does not seems to bind DNA
Secondary accessions: D3DW25 F5H3F6 Q7Z4M6Alternative splicing: 2 isoforms: Q9H503-1 Q9H503-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for BANF2: NX_Q9H503
BANF2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001014977.2 NP_001152967.1 NP_848572.3
ENSEMBL proteins: ENSP00000398738 ENSP00000367036 ENSP00000246090 ENSP00000439128
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
BANF2 for ontologies About GeneDecksing
BANF2 Antibody Products:
Assay Products for BANF2: |
Protein
Domains /
Families
for BANF2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BANF2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9H503ProtoNet protein and cluster: Q9H503 1 Blocks protein family: IPB004122 Barrier to autointegration factor
UniProtKB/Swiss-Prot: BAFL_HUMAN, Q9H503Similarity: Belongs to the BAF family |
Function
for BANF2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: BAFL_HUMAN, Q9H503Function: May play a role in BANF1 regulation and influence tissue-specific roles of BANF1
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BANF2 (see all 3)
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BANF2 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
IEA | -- |
BANF2 for ontologies About GeneDecksing
|
Pathways & Interactions
for BANF2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BANF2
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for BANF2 (ENSP000002460904) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for BANF2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for BANF2
Search CenterWatch for drugs/clinical trials and news about BANF2 / BAFL
|
Transcripts
for BANF2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BANF2 gene (3 alternative transcripts): NM_001014977.3 NM_001159495.1 NM_178477.4 Unigene Cluster for BANF2: Barrier to autointegration factor 2 Hs.115366 [show with all ESTs]Unigene Representative Sequence: BQ4287945 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000427254 ENST00000377805(uc002wqa.2) ENST00000246090(uc002wpz.2)
ENST00000467330 ENST00000545418(uc010zrs.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BANF2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BANF2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): BANF2 (NM_001014977) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BANF2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BANF2 |
Additional cDNA sequence: BC054871.1 BC062735.1 2 DOTS entries: DT.309388 DT.87046979 19 AceView cDNA sequences: NM_178477 AW022487 AA397912 BC054871 AA862555 BC062735 AA442269 BV205077 AI150321 AI075928 AI204602 AA394107 AI066604 AA382909 BU561046 AA629341 BU853192 BG459855 BQ428794
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for BANF2 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b |
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| SP1: | | | | | - | | | | | | | | | | |
| SP2: | | | | | - | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for BANF2
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Expression
for BANF2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BANF2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See BANF2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BANF2
SOURCE GeneReport for Unigene cluster: Hs.115366
UniProtKB/Swiss-Prot: BAFL_HUMAN, Q9H503Tissue specificity: Expressed strongly in testis and pancreas. Also detected in brain, colon, liver, lung, ovary,placenta, prostate, small intestine, spleen and thymus. Not detected in heart, kidney and skeletal muscle
SABiosciences Custom PCR Arrays for BANF2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BANF2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BANF2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BANF2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BANF2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BANF2 |
Orthologs
for BANF2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for BANF2 gene from 3/11 species (see all 11) About this table
ENSEMBL Gene Tree for BANF2 (if available)
TreeFam Gene Tree for BANF2 (if available) |
Paralogs
for BANF2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for BANF2 gene
- BANF12
1 SIMAP similar gene for BANF2 using alignment to 2 protein entries: BAFL_HUMAN (see all proteins):BANF1
BANF2 for paralogs About GeneDecksing
|
Genomic Variants
for BANF2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BANF2 (17674320 - 17716517 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for BANF2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BANF2 |
|
Disorders
/ Diseases
for BANF2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BANF2 for disorders About GeneDecksing
1  disease for BANF2: About MalaCardsprostatitis
Human Genome Epidemiology (HuGE) Navigator: BANF2 (1 document)
Export disorders for BANF2 gene to outside databases
|
Publications
for BANF2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BANF2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with BANF2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Barrier-to-autointegration factor-like (BAF-L): a proposed regulator of BAF. (PubMed id 16337940)1, 2, 9 Tifft K.E.... Wilson K.L. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. (PubMed id 7829101)1, 2 Robertson N.G....Morton C.C. (1994)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for BANF2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BANF2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BANF2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BANF2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for BANF2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for BANF2 gene:
Search GeneIP for patents involving BANF2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BANF2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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 |  |  |  | |
| | | | Search Tocris compounds for BANF2 |
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 | | | BANF2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BANF2 |
|  |  |  | | | | Search ThermoFisher Antibodies for BANF2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BANF2 |
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