BANF1 Gene
protein-coding GIFtS: 56
GCID: GC11P065769
|
|
barrier to autointegration factor 1
| |
Aliases for BANF1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Barrier To Autointegration Factor 11 2 | | D14S14602 | | BAF1 2 3 5 | | NGPS2 | | Breakpoint Cluster Region Protein 12 3 | | Barrier-To-Autointegration Factor2 | | BCRP12 | | BCRG13 |
Export aliases for BANF1 gene to outside databasesPrevious GC identifers: GC11P067450 GC11P066019 GC11P065544 GC11P065526 GC11P062095 |
Summaries for BANF1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for BANF1: The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecularintegration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimerwhich localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. Thisprotein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of thenuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclearmembrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multipletranscript variants encoding the same protein.(provided by RefSeq, Jan 2009) UniProtKB/Swiss-Prot: BAF_HUMAN, O75531Function: Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development.May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation duringnuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited byretroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viralDNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with theviral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires thepresence of BAF and EMD Gene Wiki entry for BANF1 (Barrier to autointegration factor 1)
|
Genomic Views for BANF1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the BANF1 gene promoter: NF-1 NF-1/L NF-kappaB Roaz RORalpha1 HSF2 NF-kappaB2 STAT3 c-Myb NF-kappaB1 Other transcription factors
Search SABiosciences Chromatin IP Primers for BANF1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BANF1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13.1 Ensembl cytogenetic band: 11q13.1 HGNC cytogenetic band: 11q13.1BANF1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P065769: view genomic region
(about GC identifiers)
Start:
|
65,769,550 bp from pter |
End:
|
65,771,620 bp from pter |
Size:
|
2,071 bases |
Orientation:
|
plus strand |
|
Proteins for BANF1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: BAF_HUMAN, O75531 (See
protein sequence)Recommended Name: Barrier-to-autointegration factor Size: 89 amino acids; 10059 Da
Subunit: Homodimer. Heterodimerizes with BAFL. Interacts with ANKLE2/LEM4, leading to decreased phosphorylation by VRK1and promoting dephosphorylation by protein phosphatase 2A (PP2A). Binds non-specifically to double-stranded DNA, andis found as a hexamer or dodecamer upon DNA binding. Binds to LEM domain-containing nuclear proteins such asLEMD3/MAN1, TMPO/LAP2 and EMD (emerin). Interacts with CRX and LMNA (lamin-A). Binds linker histone H1.1 and corehistones H3 with in vitro affinities of 500-900 and 100-200 nM. Interacts with HIV-1 pre-integration complex incytoplasm by binding to viral matrix protein and Gag polyprotein
Subcellular location: Nucleus. Cytoplasm. Chromosome. Note=Significantly enriched at the nuclear inner membrane,diffusely throughout the nucleus during interphase and concentrated at the chromosomes during the M-phase. May beincluded in HIV-1 virions via its interaction with viral GAG polyprotein. The phosphorylated form (by VRK1) shows acytoplasmic localization
Sequence caution: Sequence=AAC08964.1; Type=Frameshift; Positions=87;
6/7 PDB 3D structures from and Proteopedia for BANF1 (see all 7):1CI4 (3D)
  1QCK (3D)
  2BZF (3D)
  2EZX (3D)
  2EZY (3D)
  2EZZ (3D)
 
Secondary accessions: O60558 Q6FGG7Explore the universe of human proteins at neXtProt for BANF1: NX_O75531
Post-translational modifications:
Ser-4 is the major site of phosphorylation as compared to Thr-2 and Thr-3. Phosphorylation on Thr-2; Thr-3 and Ser-4disrupts its ability to bind DNA and reduces its ability to bind LEM domain-containing proteins. Non phosphorylatedBAF seems to enhance binding between EMD and LMNA. Dephosphorylated by protein phosphatase 2A (PP2A) followinginteraction with ANKLE2/LEM4 during mitotic exit, leading to mitotic nuclear envelope reassembly1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75531 BANF1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001137457.1 NP_003851.1 ENSEMBL proteins: ENSP00000310275 ENSP00000416128 ENSP00000431785 ENSP00000433760 ENSP00000432867 Reactome Protein details: O75531 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
BANF1 for ontologies About GeneDecksing
BANF1 Antibody Products: Assay Products for BANF1: |
Protein
Domains / Families for BANF1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BANF1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O75531ProtoNet protein and cluster: O75531 1 Blocks protein family: IPB004122 Barrier to autointegration factor
UniProtKB/Swiss-Prot: BAF_HUMAN, O75531Domain: Has a helix-hairpin-helix (HhH) structural motif conserved among proteins that bind non-specifically to DNADomain: LEM domain proteins bind centrally on the BAF dimer, whereas DNA binds to the left and right sidesSimilarity: Belongs to the BAF family |
Function for BANF1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: BAF_HUMAN, O75531Function: Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development.May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation duringnuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited byretroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viralDNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with theviral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires thepresence of BAF and EMD
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BANF1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BANF1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): BANF1 (NM_003860) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BANF1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BANF1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BANF1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
BANF1 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for BANF1:
|
Pathways & Interactions for BANF1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Clearance of Nuclear Envelope Membranes from Chromatin | | | 2 | M Phase | | | 3 | Integration of viral DNA into host genomic DNA | | | 4 | Plus-strand DNA synthesis | | | 5 | HIV Infection | |
Pathway sources See GeneCards unified pathways Show all pathways
5/23
Reactome Pathways for BANF1 (see all 23)
BANF1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BANF1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/98 Interacting proteins for BANF1 (O755313 ENSP000003102754) via UniProtKB, MINT, STRING, and/or I2D (see all 98)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
BANF1 for ontologies About GeneDecksing
|
Drugs & Compounds for BANF1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
BANF1 for compounds About GeneDecksing
Browse Tocris compounds for BANF1 1 Novoseek chemical compound relationship for BANF1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| bafilomycin a1 |
70 |
14 |
7642700 (7), 17638544 (2), 10951226 (1) |
Search CenterWatch for drugs/clinical trials and news about BANF1 / BAF 
|
Transcripts for BANF1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for BANF1 gene (2 alternative transcripts): NM_001143985.1 NM_003860.3 Unigene Cluster for BANF1: Barrier to autointegration factor 1 Hs.433759 [show with all ESTs]Unigene Representative Sequence: BM4746518 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000312175(uc001ogo.3 uc001ogp.3) ENST00000445560 ENST00000530204 ENST00000524663 ENST00000524628 ENST00000533166 ENST00000527348 ENST00000528648
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BANF1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BANF1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): BANF1 (NM_003860) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BANF1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BANF1  |
Additional cDNA sequence: AF044773.1 AF068235.1 AF070447.1 AK311961.1 BC005942.1 BC008705.1 BC107702.1 CR542140.1 17 DOTS entries: DT.449005 DT.95135076 DT.95366550 DT.120962331 DT.91772050 DT.95211261 DT.100806424 DT.120729757 DT.100880501 DT.100880503 DT.120729756 DT.100880499 DT.120729766 DT.95209324 DT.95366646 DT.120729768 DT.95366591 24/467 AceView cDNA sequences (see all 467): BQ893554 AI200846 AI282424 BX282475 AA843958 BQ684886 CD675061 BQ430476 BF771934 CK819864 AA309983 BQ278974 AA866102 AW602726 AA400061 BM670544 BM424106 BP339324 AA576285 BM142056 BM914834 BQ434664 AI186228 AI753821 GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for BANF1 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | |
| SP1: | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for BANF1
|
Expression for BANF1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BANF1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CCTCCCCCGT
About this image See BANF1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for BANF1
SOURCE GeneReport for Unigene cluster: Hs.433759 UniProtKB/Swiss-Prot: BAF_HUMAN, O75531Tissue specificity: Widely expressed. Expressed in colon, brain, heart, kidney, liver, lung, ovary, pancreas, placenta,prostate, skeletal muscle, small intestine, spleen and testis. Not detected in thymus and peripheral blood leukocytes SABiosciences Expression via Pathway-Focused PCR Array including BANF1: | HIV Host Response in human mouse rat |
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BANF1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BANF1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BANF1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BANF1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BANF1 |
Orthologs for BANF1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for BANF1 gene from 6/19 species (see all 19) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
BANF16 |
-- |
88(a) |
1 ↔ 1 |
Un(24352277-24352423) |
lizard (Anolis carolinensis) |
Reptilia |
BANF16 |
-- |
93(a) |
1 ↔ 1 |
GL344077.1(2205-2327) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.231492 |
Xenopus laevis transcribed sequence with moderate similarity more |
76.45(n) |
  |
48036749 |
zebrafish (Danio rerio) |
Actinopterygii |
banf11 |
barrier to autointegration factor 1 |
75.76(n) 82.95(a) |
  |
334717 NM_205562.1 NP_991125.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
baf1 |
barrier to autointegration factor |
64.37(n) 64.37(a) |
  |
34095 NM_135332.3 NP_609176.1 |
worm (Caenorhabditis elegans) |
Secernentea |
baf-11 |
Protein BAF-1 |
58.8(n) 59.55(a) |
  |
176330 NM_066684.4 NP_499085.1 |
ENSEMBL Gene Tree for BANF1 (if available) TreeFam Gene Tree for BANF1 (if available)  |
Paralogs for BANF1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for BANF1 gene
- BANF22
1 SIMAP similar gene for BANF1 using alignment to 2 protein entries: BAF_HUMAN (see all proteins):BANF2
BANF1 for paralogs About GeneDecksing
5 Pseudogenes.org Pseudogenes for BANF1 PGOHUM00000238655 PGOHUM00000248215 PGOHUM00000244343 PGOHUM00000240547 PGOHUM00000232957
|
Genomic Variants for BANF1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 11 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for BANF1 (65769550 - 65771620 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for BANF1: -- Human Gene Mutation Database (HGMD): BANF1
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BANF1 |
|
Disorders
/ Diseases for BANF1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BANF1 for disorders About GeneDecksing
OMIM gene information: 603811
OMIM disorders: --
UniProtKB/Swiss-Prot: BAF_HUMAN, O75531
Defects in BANF1 are the cause of Nestor-Guillermo progeria syndrome (NGPS) [MIM:614008]. NGPS is an atypicalprogeroid syndrome characterized by normal development in the first years of life, later followed by the emergence ofgeneralized lipoatrophy, severe osteoporosis, and marked osteolysis. The atrophic facial subcutaneous fat pad and themarked osteolysis of the maxilla and mandible result in a typical pseudosenile facial appearance with micrognatia,prominent subcutaneous venous patterning, a convex nasal ridge, and proptosis. Cognitive development is completelynormal. Patients do not have cardiovascular dysfunction, atherosclerosis, or metabolic anomalies 11 diseases for BANF1: About MalaCardsnestor-guillermo progeria syndrome emery-dreifuss muscular dystrophy muscular dystrophy progeria osteolysis vaccinia leiomyoma osteoporosis immunodeficiency prostatitis hiv type 1 2 diseases from the University of Copenhagen DISEASES database for BANF1:Emery-Dreifuss muscular dystrophy Progeria 2 Novoseek disease relationships for BANF1 gene About this table
Export disorders for BANF1 gene to outside databases
|
Publications for BANF1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BANF1 gene, integrated from 9 sources (see all 83): (articles sorted by number of sources associating them with BANF1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- A previously unidentified host protein protects retroviral DNA from autointegration. (PubMed id 9465049)1, 2, 3 Lee M.S. and Craigie R. (1998)
- Barrier-to-autointegration factor BAF binds p55 Gag and matrix and is a host component of human immunodeficiency virus type 1 virions. (PubMed id 14645565)1, 2, 9 Mansharamani M.... Wilson K.L. (2003)
- Barrier-to-autointegration factor-like (BAF-L): a proposed regulator of BAF. (PubMed id 16337940)1, 2, 9 Tifft K.E.... Wilson K.L. (2006)
- Barrier-to-autointegration factor: major roles in chromatin decondensation and nuclear assembly. (PubMed id 12163470)1, 2, 9 Segura-Totten M.... Wilson K.L. (2002)
- Binding of barrier to autointegration factor (BAF) to histone H3 and selected linker histones including H1.1. (PubMed id 16203725)1, 2, 9 de Oca R.M.... Wilson K.L. (2005)
- Barrier-to-autointegration factor phosphorylation on Ser-4 regulates emerin binding to lamin A in vitro and emerin localization in vivo. (PubMed id 16371512)1, 2, 9 Bengtsson L. and Wilson K.L. (2006)
- Structural basis of DNA bridging by barrier-to-autointegration factor. (PubMed id 10924106)1, 2, 9 Umland T.C.... Davies D.R. (2000)
- Both the structure and DNA binding function of the barrier-to- autointegration factor contribute to reconstitution of HIV type 1 integration in vitro. (PubMed id 11005805)1, 2, 9 Harris D. and Engelman A. (2000)
- BAF: roles in chromatin, nuclear structure and retrovirus integration. (PubMed id 15130582)1, 2, 9 Segura-Totten M. and Wilson K.L. (2004)
- BAF is required for emerin assembly into the reforming nuclear envelope. (PubMed id 11792822)1, 2, 9 Haraguchi T.... Hiraoka Y. (2001)
|
External Searches for BANF1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing BANF1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BANF1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BANF1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for BANF1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for BANF1 gene: Search GeneIP for patents involving BANF1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for BANF1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | OriGene Antibodies for BANF1 | | OriGene shRNA RFP for BANF1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BANF1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BANF1 | | OriGene Protein Over-expression Lysate for BANF1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for BANF1 | | OriGene 3'-UTR Clone for BANF1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BANF1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BANF1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for BANF1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for BANF1 | | OriGene Custom Protein Services for BANF1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BANF1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BANF1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BANF1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BANF1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BANF1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BANF1 |
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| | | Search Tocris compounds for BANF1 |
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 | | BANF1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BANF1 |
|  |  |  | | | ThermoFisher Antibodies for BANF1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BANF1 |
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