Aliases for BAK1 Gene
Aliases for BAK1 Gene
External Ids for BAK1 Gene
- HGNC: 949
- Entrez Gene: 578
- Ensembl: ENSG00000030110
- OMIM: 600516
- UniProtKB: Q16611
Previous HGNC Symbols for BAK1 Gene
- CDN1
Previous GeneCards Identifiers for BAK1 Gene
- GC06M033542
- GC06M033588
- GC06M033489
- GC06M033648
- GC06M033281
- GC06M033541
Summaries for BAK1 Gene
-
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
GeneCards Summary for BAK1 Gene
BAK1 (BCL2 Antagonist/Killer 1) is a Protein Coding gene. Diseases associated with BAK1 include Benign Mammary Dysplasia and Chronic Gonococcal Salpingitis. Among its related pathways are Apoptosis and Autophagy and Platinum drug resistance. GO annotations related to this gene include protein homodimerization activity and protein heterodimerization activity. An important paralog of this gene is BCL2.
UniProtKB/Swiss-Prot for BAK1 Gene
-
In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BAK1 Gene
Genomics for BAK1 Gene
Regulatory Elements for BAK1 Gene
Enhancers for BAK1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around BAK1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the BAK1 gene promoter:
Regulatory Element Products
Genomic Location for BAK1 Gene
- Chromosome:
- 6
- Start:
- 33,572,546 bp from pter
- End:
- 33,580,299 bp from pter
- Size:
- 7,754 bases
- Orientation:
- Minus strand
Genomic View for BAK1 Gene
Genes around BAK1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p21.31 by Ensembl
- 6p21.31 by Entrez Gene
- 6p21.31 by HGNC
BAK1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for BAK1 Gene
Proteins for BAK1 Gene
-
Protein details for BAK1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q16611-BAK_HUMAN
- Recommended name:
- Bcl-2 homologous antagonist/killer
- Protein Accession:
- Q16611
- C0H5Y7
- Q6I9T6
- Q92533
Protein attributes for BAK1 Gene
- Size:
- 211 amino acids
- Molecular mass:
- 23409 Da
- Quaternary structure:
-
- Interacts with BCL2A1 (By similarity). Homodimer. Formation of the homodimer is zinc-dependent. Forms heterodimers with BCL2, E1B 19k protein, and BCL2L1 isoform Bcl-X(L). Interacts with BOP/C22orf29. Interacts with VDAC1 (PubMed:25296756).
- (Microbial infection) Interacts with vaccinia virus protein F1 (PubMed:16439990). Interacts with myxoma virus protein M11L (PubMed:17386268).
Three dimensional structures from OCA and Proteopedia for BAK1 Gene
Protein Expression for BAK1 Gene
Post-translational modifications for BAK1 Gene
Other Protein References for BAK1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore top BAK1 Antibody
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for BAK1
- R&D Systems Antibodies for BAK1 (BAK)
- Cell Signaling Technology (CST) Antibodies for BAK1 (BAK1)
- Novus Biologicals Antibodies for BAK1
- Invitrogen Antibodies for BAK1
- antibodies-online Antibodies for BAK1: See all 189
- GeneTex BAK1 antibody for BAK1
-
Custom Antibody ServicesProSci Antibodies for BAK1
-
Santa Cruz Biotechnology (SCBT) Antibodies for BAK1
Protein Products
- R&D Systems Proteins and Enzymes for BAK1 (BAK)
-
OriGene Purified Proteins for BAK1
- Search Origene for MassSpec and Protein Over-expression Lysates for BAK1
- Origene Custom Protein Services for BAK1
- antibodies-online Proteins for BAK1: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for BAK1
Assay Products
- antibodies-online Kits for BAK1: See all 38
No data available for DME Specific Peptides for BAK1 Gene
Domains & Families for BAK1 Gene
Gene Families for BAK1 Gene
- HGNC:
Protein Domains for BAK1 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for BAK1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q16611UniProtKB/Swiss-Prot:
BAK_HUMAN :- Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
- Belongs to the Bcl-2 family.
- Domain:
-
- Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
- Family:
-
- Belongs to the Bcl-2 family.
Function for BAK1 Gene
Molecular function for BAK1 Gene
- GENATLAS Biochemistry:
- BCL2-antagonist/killer 1,BAX subfamily
- UniProtKB/Swiss-Prot Function:
- In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
| GO:0005515 | protein binding | IPI | 9111042 |
| GO:0031072 | heat shock protein binding | IEA | -- |
| GO:0042802 | identical protein binding | IPI | 15901672 |
| GO:0042803 | protein homodimerization activity | IEA | -- |
Phenotypes for BAK1 Gene
- MGI mutant phenotypes for BAK1:
-
inferred from 1 alleles
- mortality/aging
- cellular phenotype
- behavior/neurological phenotype
- normal phenotype
- immune system phenotype
- nervous system phenotype
- homeostasis/metabolism phenotype
- neoplasm
- reproductive system phenotype
- endocrine/exocrine gland phenotype
- hearing/vestibular/ear phenotype
- limbs/digits/tail phenotype
- skeleton phenotype
- hematopoietic system phenotype
- renal/urinary system phenotype
- GenomeRNAi human phenotypes for BAK1:
-
- Decreased hepcidin::fluc mRNA expression
- Mildly decreased CFP-tsO45G cell surface transport
- Increased transferrin (TF) endocytosis
- Increased HPV18 LCR reporter activity
- Synthetic lethal with MLN4924 (a NAE inhibitor)
- Increased viability with MLN4924 (a NAE inhibitor)
- Increased viability with SS1P at EC90
Animal Models for BAK1 Gene
- MGI Knock Outs for BAK1:
-
- Bak1 tm1Thsn
Animal Model Products
-
Taconic Biosciences Mouse Models for BAK1
- Cyagen custom Knockout/knockin (KOKI) mouse models for BAK1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for BAK1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for BAK1 gene
- Search ViGene Biosciences for BAK1
miRNA for BAK1 Gene
- miRTarBase miRNAs that target BAK1
-
- hsa-mir-125b-5p (MIRT002394)
- hsa-mir-125a-5p (MIRT005350)
- hsa-mir-375 (MIRT019714)
- hsa-mir-92a-3p (MIRT048976)
- hsa-mir-887-5p (MIRT494540)
- hsa-mir-4507 (MIRT494541)
- hsa-mir-3940-5p (MIRT494542)
- hsa-mir-6779-5p (MIRT494543)
- hsa-mir-6780a-5p (MIRT494544)
- hsa-mir-3689c (MIRT494545)
- hsa-mir-3689b-3p (MIRT494546)
- hsa-mir-3689a-3p (MIRT494547)
- hsa-mir-30b-3p (MIRT494548)
- hsa-mir-1273h-5p (MIRT494549)
- hsa-mir-6788-5p (MIRT494550)
- hsa-mir-30c-2-3p (MIRT494551)
- hsa-mir-30c-1-3p (MIRT494552)
- hsa-mir-3606-5p (MIRT494553)
- hsa-mir-4425 (MIRT494554)
- hsa-mir-1257 (MIRT494555)
- hsa-mir-142-3p (MIRT494556)
- hsa-mir-6073 (MIRT494557)
- hsa-mir-92a-1-5p (MIRT494558)
- hsa-mir-920 (MIRT494559)
- hsa-mir-5591-5p (MIRT494560)
- hsa-mir-6726-5p (MIRT494561)
- hsa-mir-4300 (MIRT494562)
- hsa-mir-6090 (MIRT494563)
- hsa-mir-6827-5p (MIRT494564)
- hsa-mir-4790-3p (MIRT494565)
- hsa-mir-6754-3p (MIRT494566)
- hsa-mir-412-3p (MIRT494567)
- hsa-mir-20b-3p (MIRT494568)
- hsa-mir-6765-3p (MIRT494569)
- hsa-mir-3622b-3p (MIRT494570)
- hsa-mir-3622a-3p (MIRT494571)
- hsa-mir-4506 (MIRT494572)
- hsa-mir-4680-5p (MIRT526685)
- hsa-mir-6787-3p (MIRT526686)
- hsa-mir-8073 (MIRT526687)
- hsa-mir-221-5p (MIRT526688)
- hsa-mir-7157-5p (MIRT526689)
- hsa-mir-4310 (MIRT526690)
- hsa-mir-1245b-3p (MIRT526691)
- hsa-mir-1272 (MIRT526692)
- hsa-mir-3145-5p (MIRT568298)
- hsa-mir-6734-5p (MIRT568299)
- hsa-mir-4710 (MIRT568300)
- hsa-mir-4450 (MIRT568301)
- hsa-mir-5194 (MIRT568302)
- hsa-mir-6738-5p (MIRT568303)
- hsa-mir-1914-3p (MIRT568304)
- hsa-mir-423-5p (MIRT568305)
- hsa-mir-3184-5p (MIRT568306)
- hsa-mir-32-5p (MIRT568307)
- hsa-mir-25-3p (MIRT568308)
- hsa-mir-363-3p (MIRT568309)
- hsa-mir-367-3p (MIRT568310)
- hsa-mir-92b-3p (MIRT568311)
miRNA Products
- Search ViGene Biosciences for BAK1
Inhibitory RNA Products
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-
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Clone Products
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- VectorBuilder custom plasmid, inducible vectors for BAK1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BAK1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for BAK1
-
ViGene Biosciences adenoviral particle packaged cDNA for BAK1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for BAK1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for BAK1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for BAK1 Gene
Localization for BAK1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for BAK1 Gene
- Mitochondrion membrane; Single-pass membrane protein.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| cytosol | 4 |
| plasma membrane | 2 |
| endoplasmic reticulum | 2 |
| extracellular | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IEA | -- |
| GO:0005739 | mitochondrion | IDA | 9843949 |
| GO:0005741 | mitochondrial outer membrane | TAS | -- |
| GO:0005783 | endoplasmic reticulum | IEA | -- |
| GO:0005829 | cytosol | IEA | -- |
Pathways & Interactions for BAK1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Apoptosis Modulation and Signaling |
.41
|
.33
|
| 2 | Nanomaterial induced apoptosis | ||
| 3 | Apoptotic Pathways in Synovial Fibroblasts | ||
| 4 | CDK-mediated phosphorylation and removal of Cdc6 |
.31
|
|
| 5 | MicroRNAs in cancer | ||
Pathways by source for BAK1 Gene
2 GeneTex pathways for BAK1 Gene
1 Cell Signaling Technology pathway for BAK1 Gene
9 BioSystems pathways for BAK1 Gene
4 Reactome pathways for BAK1 Gene
1 PharmGKB pathway for BAK1 Gene
6 KEGG pathways for BAK1 Gene
1 GeneGo (Thomson Reuters) pathway for BAK1 Gene
3 R&D Systems pathways for BAK1 Gene
4 Qiagen pathways for BAK1 Gene
Interacting Proteins for BAK1 Gene
Selected Interacting proteins:
ENSP00000353878
Q16611-BAK_HUMAN
for BAK1 Gene via
STRING
MINT
UniProtKB
IID
SIGNOR curated interactions for BAK1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001782 | B cell homeostasis | IEA | -- |
| GO:0001783 | B cell apoptotic process | IEA | -- |
| GO:0001836 | release of cytochrome c from mitochondria | IGI | 21041309 |
| GO:0001974 | blood vessel remodeling | IEA | -- |
| GO:0002262 | myeloid cell homeostasis | IEA | -- |
Transcripts for BAK1 Gene
mRNA/cDNA for BAK1 Gene
- (3) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (231) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for BAK1 Gene
miRNA Products
- Search ViGene Biosciences for BAK1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for BAK1
- Browse OriGene Inhibitory RNA Products For BAK1
-
ViGene Biosciences ready-to-package AAV shRNAs for BAK1 gene
Clone Products
- Sino Biological Human cDNA Clone for BAK1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for BAK1
- VectorBuilder custom plasmid, inducible vectors for BAK1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BAK1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for BAK1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Epidermis (Integumentary System)
- Corneocytes Stratified Epidermis
- Granular Keratinocytes Stratified Epidermis
- Spinous Keratinocytes Stratified Epidermis
-
Epithelial Cells
- Corneocytes Stratified Epidermis
- Granular Keratinocytes Stratified Epidermis
- Spinous Keratinocytes Stratified Epidermis
-
Heart (Cardiovascular System)
- Atrioventricular Canal Cells Atrioventricular Canal
- Intestine (Gastrointestinal Tract)
This gene is overexpressed in Nasal epithelium (45.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for BAK1 Gene
NURSA nuclear receptor signaling pathways regulating expression of BAK1 Gene:
BAK1SOURCE GeneReport for Unigene cluster for BAK1 Gene:
Hs.485139mRNA Expression by UniProt/SwissProt for BAK1 Gene:
Q16611-BAK_HUMAN
Tissue specificity:
Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
Evidence on tissue expression from TISSUES for BAK1 Gene
- Lung(4.2)
- Nervous system(4.1)
Primer Products
-
OriGene qPCR primer pairs for BAK1
-
OriGene qPCR primer pairs and template standards for BAK1
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for BAK1 Gene
Orthologs for BAK1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | BAK1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | LOC481744 34 |
|
||
| BAK1 35 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | BAK1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Bak1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Bak1 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | BAK1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | BAK1 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | BAK1 35 |
|
OneToOne |
- Species where no ortholog for BAK1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for BAK1 Gene
(2) SIMAP similar genes for BAK1 Gene using alignment to 2 proteins:
Pseudogenes.org Pseudogenes for BAK1 Gene
Variants for BAK1 Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000219106 | -- | 33,576,888(+) | ACAGT(A/C)CCGGG | intron-variant | |
| rs1000239166 | -- | 33,579,599(+) | AGTGG(C/T)CTAAA | intron-variant | |
| rs1000317999 | -- | 33,579,881(+) | CAGGA(C/T)CAGGT | intron-variant | |
| rs1000541998 | -- | 33,579,483(+) | CTCCA(A/G)CTCCC | intron-variant | |
| rs1000760266 | -- | 33,573,200(+) | TGGCC(A/G)GAGGG | utr-variant-3-prime |
Residual Variation Intolerance Score:
65.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.48;
28.95% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for BAK1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- BAK1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BAK1 Gene
Disorders for BAK1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| benign mammary dysplasia |
|
|
| chronic gonococcal salpingitis |
|
|
| testicular germ cell tumor |
|
|
| acute salpingitis |
|
|
| chronic salpingitis |
|
|
Search BAK1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for BAK1
No data available for UniProtKB/Swiss-Prot and Genatlas for BAK1 Gene
Publications for BAK1 Gene
- Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak. (PMID: 7715731) Kiefer M.C. … Barr P.J. (Nature 1995) 2 3 4 22 64
- BAK, BAX, and NBK/BIK proapoptotic gene alterations in Iranian patients with ataxia telangiectasia. (PMID: 19898928) Isaian A. … Sanati M.H. (J. Clin. Immunol. 2010) 3 22 46 64
- Interaction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosis. (PMID: 16439990) Postigo A. … Way M. (Cell Death Differ. 2006) 3 4 22 64
- Induction of apoptosis by the Bcl-2 homologue Bak. (PMID: 7715730) Chittenden T. … Guild B.C. (Nature 1995) 2 3 4 64
- Plasminogen kringle 5 induces endothelial cell apoptosis by triggering a voltage-dependent anion channel 1 (VDAC1) positive feedback loop. (PMID: 25296756) Li L. … Gao G.Q. (J. Biol. Chem. 2014) 3 4 64
Products for BAK1 Gene
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- Novus Biologicals Antibodies for BAK1
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- Novus Biologicals
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- Taconic Biosciences Mouse Models for BAK1
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Addgene plasmids for BAK1
- antibodies-online Antibodies for BAK1: See all 189
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- Search antibodies-online for peptides
- GeneTex BAK1 antibody for BAK1
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- ViGene Biosciences adenoviral particle packaged cDNA for BAK1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for BAK1 gene
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- Search ViGene Biosciences for BAK1
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- Santa Cruz Biotechnology (SCBT) CRISPR for BAK1
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- Search for BAK1 Proteins at ProSci
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- Cyagen custom Knockout/knockin (KOKI) mouse models for BAK1
- VectorBuilder custom plasmid, inducible vectors for BAK1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BAK1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for BAK1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer