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Aliases & Descriptions for BAIAP3
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| BAP3 1, 2, 3, 5 | | KIAA0734 1, 2, 3 | | MGC138334 2 |
| | | Descriptions |
|---|
| BAI-associated protein 3 2 | | BAI1-associated protein 3 2 |
|
| | Search outside databases for aliases for BAIAP3 genePrevious GC identifer: GC16P001400 |
Summaries for BAIAP3(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for BAIAP3: This p53-target gene encodes a brain-specific angiogenesis inhibitor. The protein is a seven-span transmembrane protein and a member of the secretin receptor family. It interacts with the cytoplasmic region of brain-specific angiogenesis inhibitor 1. This protein also contains two C2 domains, which are often found in proteins involved in signal transduction or membrane trafficking. Its expression pattern and similarity to other proteins suggest that it may be involved in synaptic functions. [provided by RefSeq] Gene Wiki entry for BAIAP3 |
Genomic Location for BAIAP3
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the BAIAP3 gene 
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3BAIAP3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P001324:
(about GC identifiers)
Start:
|
1,323,655 bp from pter |
End:
|
1,339,443 bp from pter |
Size:
|
15,789 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000016.8 NT_037887.4
| Proteins for BAIAP3
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: BAIP3_HUMAN, O94812 (See
protein sequence)Recommended Name: BAI1-associated protein 3 Size: 1187 amino acids; 131901 Da
Subunit: Interacts with BAI1
Secondary accessions: B2RCD7 O94839 Q2M226 Q658J2 Q76N05 Q96RZ3 Q9UJK1Alternative splicing: 2 isoforms: O94812-1 O94812-2 Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_003924.2
ENSEMBL proteins: ENSP00000380625 ENSP00000380626 ENSP00000324510
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for BAIAP3: Assays for BAIAP3: | Protein
Domains/ Families for BAIAP3(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry O94812
ProtoNet protein and cluster: O94812 2 Blocks protein families: IPB000008 C2 domain IPB010439 Protein of unknown function DUF1041
UniProtKB/Swiss-Prot: BAIP3_HUMAN, O94812Similarity: Contains 2 C2 domainsSimilarity: Contains 1 MHD1 (MUNC13 homology domain 1) domainSimilarity: Contains 1 MHD2 (MUNC13 homology domain 2) domain | Gene Function for BAIAP3
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003933
Applied Biosystems Silencer® siRNAs for BAIAP3
Sigma-Aldrich siRNA for BAIAP3  Sigma-Aldrich shRNA for BAIAP3  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_003933                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_003933                                  untagged cDNA clone in CMV expression vector: NM_003933 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_003933
Genatlas biochemistry entry for BAIAP3:brain-specific angiogenesis inhibitor (BAI1)-associated protein 3,predominantly expressed in brain,homolog to synaptotagmin,potentially regulating the release of neurotransmitters1 Gene Ontology (GO) molecular function term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008022 | protein C-terminus binding |
TAS | 9790924 | About this table | Pathways & Interactions for BAIAP3
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
Gene Network CentralTM Interacting Genes and Proteins Network for BAIAP3 
5 Interacting proteins for BAIAP3 (ENSP000003245103 O948121) via UniProtKB, MINT, and/or STRINGAbout this table
1 Gene Ontology (GO) biological process term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007269 | neurotransmitter secretion |
TAS | 9790924 | About this table
|
Drugs & Compounds for BAIAP3(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for BAIAP3
|
Transcripts for BAIAP3(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003933
Sigma-Aldrich siRNA for BAIAP3  Sigma-Aldrich shRNA for BAIAP3  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_003933 REFSEQ mRNAs for BAIAP3 gene: NM_003933.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_003933               OriGene GFP tagged cDNA clone in CMV expression vector: NM_003933                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_003933                                  untagged cDNA clone in CMV expression vector: NM_003933  Additional cDNA sequence: AB018277.2 AF038191.1 AK294491.1 AK294576.1 AK294744.1 AK295645.1 AK299309.1 AK299358.1 AK315059.1 AL834321.1 BC104966.1 BC112129.1 10 DOTS entries: DT.75118306 DT.100815748 DT.100815756 DT.95161516 DT.92435001 DT.120662077 DT.120662127 DT.449556 DT.92434995 DT.91706459 24/87 AceView cDNA sequences (see all 87
):AB018277 CB148214 AI564977 BF448577 BI771405 NM_003933 BM981388 BP348862 AI696810 CB153038 BM827931 CD106045 CB155761 CD251629 BQ425972 BQ277755 F13300 BI831797 BG707986 BU948670 BE869971 BI914498 BI755009 AL041517
highest scoring ESTs for BAIAP3:AB018277 AA078749 AA079823 AA682952 AA782001 AI358964 AI537389 AI564977 AI696810 AI816746 Unigene Cluster for BAIAP3: BAI1-associated protein 3 Hs.458427 [show with all ESTs]Unigene Representative Sequence: AL834321
GeneLoc Exon Structure
5/24 Alternative Splicing Database (ASD) splice patterns (SP) for BAIAP3 (see all 24
)
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 15a | · | 15b | · | 15c | · | 15d | ^ | 16a | · | 16b | · | 16c | ^ | 17a | · | 17b | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | · | 21c | ^ | 22 | ^ | 23a | · | 23b | ^ | 24a | · | 24b | ^ | 25a | · | 25b | · | 25c | ^ | 26 | ^ | 27a | · | 27b | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 28a | · | 28b | · | 28c | ^ | 29 | ^ | 30a | · | 30b | ^ | 31 | ^ | 32 | ^ | 33a | · | 33b | ^ | 34 | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for BAIAP3
3 Ensembl transcripts including schematic representations: ENST00000397488
ENST00000397489
ENST00000324385
|
Expression for BAIAP3
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| BAIAP3 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for BAIAP3
1 / 2 / 3 5 probe-sets matching BAIAP3 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.458427
Expression variation in blood from EXPOLDB for BAIAP3 UniProtKB/Swiss-Prot: BAIP3_HUMAN, O94812Tissue specificity: Predominantly expressed in brain |
Orthologs for BAIAP3
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for BAIAP3 gene from 5/9 species (see all 9
)
About this table Species with no ortholog for BAIAP3
ENSEMBL Gene Tree for BAIAP3 | Paralogs for BAIAP3(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for BAIAP3 gene
- UNC13D2
|
SNPs/Variants for BAIAP3(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for BAIAP3 (up to first 250kb)
|
Disorders & Mutations for BAIAP3
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 604009
|
Medical News for BAIAP3(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for BAIAP3 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/15 PubMed articles for BAIAP3 gene (see all 15
):- Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1. (PubMed id 9790924)1, 2, 3, 4 Shiratsuchi T.... Nakamura Y. (1998)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)3, 4 Martin J.... Pennacchio L.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)3, 4 Gerhard D.S....Malek J. (2004)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)3, 4 Nakajima D.... Nagase T. (2002)
- Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)3, 4 Daniels R.J....Higgs D.R. (2001)
- Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)3, 4 Nagase T....Ohara O. (1998)
- The full-ORF clone resource of the German cDNA Consortium. (PubMed id 17974005)4 Bechtel S....Schupp I. (2007)
- The LIFEdb database in 2006. (PubMed id 16381901)3 Mehrle A....Wiemann S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)4 Ota T....Sugano S. (2004)
- From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)3 Wiemann S....Poustka A. (2004)
|
Search for BAIAP3
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing BAIAP3
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing BAIAP3
(According to HUGE)
About This Section
| |
Specialized Databases showing BAIAP3(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for BAIAP3(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for BAIAP3:

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| | | | Search Tocris compounds for BAIAP3 |
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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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