Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



BAIAP3 Gene

protein-coding   GIFtS: 57
GCID: GC16P001383

BAI1-Associated Protein 3

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
BAI1-Associated Protein 31 2
BAP32 3 5
BAI-Associated Protein 32
KIAA07343

External Ids:    HGNC: 9481   Entrez Gene: 89382   Ensembl: ENSG000000075167   OMIM: 6040095   UniProtKB: O948123   

Export aliases for BAIAP3 gene to outside databases

Previous GC identifers: GC16P001400 GC16P001324


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for BAIAP3 Gene:
This p53-target gene encodes a brain-specific angiogenesis inhibitor. The protein is a seven-span transmembrane
protein and a member of the secretin receptor family. It interacts with the cytoplasmic region of brain-specific
angiogenesis inhibitor 1. This protein also contains two C2 domains, which are often found in proteins involved
in signal transduction or membrane trafficking. Its expression pattern and similarity to other proteins suggest
that it may be involved in synaptic functions. Several transcript variants encoding different isoforms have been
found for this gene. (provided by RefSeq, Nov 2010)

GeneCards Summary for BAIAP3 Gene:
BAIAP3 (BAI1-associated protein 3) is a protein-coding gene. GO annotations related to this gene include protein C-terminus binding. An important paralog of this gene is UNC13D.

Gene Wiki entry for BAIAP3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NC_018927.2  NT_010393.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the BAIAP3 gene promoter:
         HEN1   AP-1   p300   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBAIAP3 promoter sequence
   Search Chromatin IP Primers for BAIAP3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BAIAP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

BAIAP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BAIAP3 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P001383:  view genomic region     (about GC identifiers)

Start:
1,383,602 bp from pter      End:
1,399,442 bp from pter
Size:
15,841 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: BAIP3_HUMAN, O94812 (See protein sequence)
Recommended Name: BAI1-associated protein 3  
Size: 1187 amino acids; 131901 Da
Subunit: Interacts with BAI1
Sequence caution: Sequence=BAA34454.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAG57886.1; Type=Erroneous termination; Positions=717; Note=Translated as Gly;
Secondary accessions: B2RCD7 B4DGS5 B4DIK3 B4DRK9 B4DRP1 E7EUB9 H3BUH8 H3BVI3 H7C2Q1 O94839
Q2M226 Q658J2 Q76N05 Q96RZ3 Q9UJK1
Alternative splicing: 6 isoforms:  O94812-1   O94812-2   O94812-3   O94812-5   O94812-6   O94812-7   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BAIAP3: NX_O94812

Explore proteomics data for BAIAP3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See BAIAP3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001186025.1  NP_001186026.1  NP_001186027.1  NP_001186028.1  NP_001273393.1  NP_003924.2  

    ENSEMBL proteins: 
     ENSP00000407242   ENSP00000380625   ENSP00000458134   ENSP00000457644   ENSP00000324510  
     ENSP00000409533   ENSP00000457947   ENSP00000455414   ENSP00000380626  

    BAIAP3 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for BAIAP3
    OriGene Protein Over-expression Lysate for BAIAP3
    OriGene MassSpec for BAIAP3
    OriGene Custom Protein Services for BAIAP3
    GenScript Custom Purified and Recombinant Proteins Services for BAIAP3
    Novus Biologicals BAIAP3 Protein
    Novus Biologicals BAIAP3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for BAIAP3

     
    Search eBioscience for Proteins for BAIAP3 

     
    antibodies-online proteins for BAIAP3 (2 products) 

     
    antibodies-online peptides for BAIAP3

    BAIAP3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for BAIAP3
    OriGene Custom Antibody Services for BAIAP3
    Novus Biologicals BAIAP3 Antibodies
    Abcam antibodies for BAIAP3
    Cloud-Clone Corp. Antibodies for BAIAP3
    ThermoFisher Antibodies for BAIAP3
    antibodies-online antibodies for BAIAP3 (32 products) 

    BAIAP3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for BAIAP3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for BAIAP3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for BAIAP3
    Cloud-Clone Corp. CLIAs for BAIAP3
    Search eBioscience for ELISAs for BAIAP3 
    antibodies-online kits for BAIAP3 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    4 InterPro protein domains:
     IPR014772 Munc13_dom-2
     IPR019558 Munc13_subgr_dom-2
     IPR014770 Munc13_1
     IPR000008 C2_dom

    Graphical View of Domain Structure for InterPro Entry O94812

    ProtoNet protein and cluster: O94812

    2 Blocks protein domains:
    IPB000008 C2 domain
    IPB010439 Protein of unknown function DUF1041


    UniProtKB/Swiss-Prot: BAIP3_HUMAN, O94812
    Similarity: Contains 2 C2 domains
    Similarity: Contains 1 MHD1 (MUNC13 homology domain 1) domain
    Similarity: Contains 1 MHD2 (MUNC13 homology domain 2) domain


    Find genes that share domains with BAIAP3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:
         Genatlas biochemistry entry for BAIAP3:
    brain-specific angiogenesis inhibitor (BAI1)-associated protein 3,predominantly expressed in brain,homolog to
    synaptotagmin,potentially regulating the release of neurotransmitters

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008022protein C-terminus binding TAS9790924
         
    Find genes that share ontologies with BAIAP3           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for BAIAP3:
     Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Increased cell number in G2M,  

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for BAIAP3

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat BAIAP3 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate BAIAP3:
    hsa-miR-362-3p hsa-miR-127-5p hsa-miR-329
    SwitchGear 3'UTR luciferase reporter plasmidBAIAP3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for BAIAP3
    Predesigned siRNA for gene silencing in human, mouse, rat BAIAP3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for BAIAP3

    Clone
    Products:
         
    OriGene clones in human, mouse for BAIAP3 (see all 20)
    OriGene ORF clones in mouse, rat for BAIAP3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): BAIAP3 (NM_001199097)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BAIAP3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BAIAP3

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for BAIAP3
    Browse ESI BIO Cell Lines and PureStem Progenitors for BAIAP3 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BAIAP3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol1
    extracellular1
    lysosome1
    mitochondrion1
    nucleus1
    peroxisome1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for BAIAP3 About    
    See pathways by source

    SuperPathContained pathways About
    1Transcriptional misregulation in cancer
    Transcriptional misregulation in cancer


    Find genes that share SuperPaths with BAIAP3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for BAIAP3):
        Transcriptional misregulation in cancer

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BAIAP3
    Interactions:

        GeneGlobe Interaction Network for BAIAP3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for BAIAP3 (O948123 ENSP000003245104) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BAI1O145143, ENSP000003130464I2D: score=3 STRING: ENSP00000313046
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway IPI9790924
    GO:0007269neurotransmitter secretion TAS9790924

    Find genes that share ontologies with BAIAP3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BAIAP3 (BAIP3)

    2 PharmGKB related drug/compound annotations for BAIAP3 gene    About this table
    Drug/compound PharmGKB Annotation
    cisplatinCA  
    irinotecanCA  



    Find genes that share compounds with BAIAP3           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for BAIAP3 gene (6 alternative transcripts): 
    NM_001199096.1  NM_001199097.1  NM_001199098.1  NM_001199099.1  NM_001286464.1  NM_003933.4  

    Unigene Cluster for BAIAP3:

    BAI1-associated protein 3
    Hs.458427  [show with all ESTs]
    Unigene Representative Sequence: NM_003933
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000426824 ENST00000565665 ENST00000397488(uc010uuz.2 uc010uva.2 uc021tag.1 uc002clj.3)
    ENST00000562208 ENST00000568887 ENST00000567825(uc010uvb.2) ENST00000324385(uc002clk.2)
    ENST00000421665 ENST00000568198 ENST00000566162 ENST00000561602 ENST00000561793
    ENST00000564213 ENST00000567203 ENST00000566389 ENST00000397489(uc010uvc.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat BAIAP3 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate BAIAP3:
    hsa-miR-362-3p hsa-miR-127-5p hsa-miR-329
    SwitchGear 3'UTR luciferase reporter plasmidBAIAP3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for BAIAP3
    Predesigned siRNA for gene silencing in human, mouse, rat BAIAP3
    Clone
    Products:
         
    OriGene clones in human, mouse for BAIAP3 (see all 20)
    OriGene ORF clones in mouse, rat for BAIAP3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): BAIAP3 (NM_001199097)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BAIAP3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BAIAP3
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for BAIAP3
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat BAIAP3
      QuantiTect SYBR Green Assays in human, mouse, rat BAIAP3
      QuantiFast Probe-based Assays in human, mouse, rat BAIAP3

    Additional mRNA sequence: 

    AB018277.2 AF038191.1 AK294491.1 AK294576.1 AK294744.1 AK295645.1 AK299309.1 AK299358.1 
    AK315059.1 AL834321.1 BC104966.1 BC112129.1 

    8 DOTS entries:

    DT.75118306  DT.100815748  DT.100815756  DT.95161516  DT.120662077  DT.120662127  DT.92434995  DT.91706459 

    Selected AceView cDNA sequences (see all 87):

    AI696810 BI771405 NM_003933 CB148214 CB153038 AB018277 CB155761 AI564977 
    BQ425972 BM827931 CD251629 BF448577 BQ277755 CD106045 BM981388 BP348862 
    BM548247 AL118986 BM544695 BI831797 BM828573 BF967425 BE869971 BI755009 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for BAIAP3 (see all 24)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13a · 13b ^ 14 ^
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 15a · 15b · 15c · 15d ^ 16a · 16b · 16c ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21a · 21b · 21c ^ 22 ^ 23a · 23b ^ 24a · 24b ^ 25a · 25b · 25c ^ 26 ^ 27a · 27b ^
    SP1:                                            -                                                                                                               
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 28a · 28b · 28c ^ 29 ^ 30a · 30b ^ 31 ^ 32 ^ 33a · 33b ^ 34
    SP1:                                                                  
    SP2:  -                                                               
    SP3:                                                                  
    SP4:  -     -                                                         
    SP5:  -                                                               


    ECgene alternative splicing isoforms for BAIAP3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    BAIAP3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    BAIAP3 Expression
    About this image


    BAIAP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 3 entries
             Peripheral blood-derived hematopoietic stem cells (family)
             nk cells   
     
     Spinal Cord (Nervous System)
    BAIAP3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BAIAP3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.458427

    UniProtKB/Swiss-Prot: BAIP3_HUMAN, O94812
    Tissue specificity: Predominantly expressed in brain

        Custom PCR Arrays for BAIAP3
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for BAIAP3
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat BAIAP3
    QuantiTect SYBR Green Assays in human, mouse, rat BAIAP3
    QuantiFast Probe-based Assays in human, mouse, rat BAIAP3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BAIAP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for BAIAP3 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Baiap31 , 5 BAI1-associated protein 31, 5 85.12(n)1
    89.12(a)1
      17 (12.53 cM)5
    5451921  NM_001163270.11  NP_001156742.11 
     252426595 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.190052 Transcribed sequence with weak similarity to protein more 75.47(n)    BX772583.1 
    zebrafish
    (Danio rerio)
    Actinopterygii baiap31 BAI1-associated protein 3 57.73(n)
    49.52(a)
      564728  XM_003198157.2  XP_003198205.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta unc-13-4A1 , 3 neurotransmitter secretion3
    unc-13-4A1
    33(a)
    (best of 2)3
    48.41(n)1
    36.6(a)1
      65F23
    388011  NM_139839.51  NP_648096.41 
    worm
    (Caenorhabditis elegans)
    Secernentea F54G2.11 , 3 F54G2.11 27(a)3
    43.54(n)1
    31.9(a)1
      X(2657047-2666007)3
    1805621  NM_001029540.31  NP_001024711.11 


    ENSEMBL Gene Tree for BAIAP3 (if available)
    TreeFam Gene Tree for BAIAP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for BAIAP3 gene
    UNC13D2  
    1 SIMAP similar gene for BAIAP3 using alignment to 4 protein entries:     BAIP3_HUMAN (see all proteins):
    UNC13D

    Find genes that share paralogs with BAIAP3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for BAIAP3 (see all 775)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1162695151,2
    C,F--1309948(+) GTGTCG/ACTCGG 3 -- int11Minor allele frequency- A:0.01WA 118
    rs1499029191,2
    C--1309952(+) CGCTCG/TGATCG 3 -- int10--------
    rs727792061,2
    C,F--1310701(+) TGTTCT/GGGAAG 1 -- us2k12Minor allele frequency- G:0.29NA EA 240
    rs1880359441,2
    --1310741(+) CTTCGA/GGTGAA 1 -- us2k10--------
    rs800261911,2
    C,F--1310808(+) GCTGTA/TTTCGA 1 -- us2k13Minor allele frequency- T:0.17WA NA EA 358
    rs80601081,2
    C,F,A,H--1310819(+) CCAAGC/GGCAGG 1 -- us2k111Minor allele frequency- G:0.06NA WA CSA EA 372
    rs37599361,2
    C,F,H--1381680(+) GAAACG/AGAGGC 3 -- us2k112Minor allele frequency- A:0.24EA NS NA WA 2238
    rs109030061,2
    C,H--1381707(+) ACTCAG/ACCTAT 3 -- us2k112Minor allele frequency- A:0.05NA WA CSA EA 374
    rs9099141,2
    C,F,O,H--1381714(+) CTATCG/ACTATG 3 -- us2k124Minor allele frequency- A:0.13MN NS EA NA WA CSA 2202
    rs1477317901,2
    --1381772(+) CTAGAA/CAAGAG 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for BAIAP3 (1383602 - 1399442 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for BAIAP3 (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2750326CNV Deletion23290073
    esv2750325CNV Deletion23290073
    esv2422427CNV Duplication17116639
    nsv904954CNV Loss21882294
    dgv2505n71CNV Loss21882294
    nsv904950CNV Loss21882294
    dgv2528n71CNV Loss21882294
    dgv2527n71CNV Loss21882294
    nsv904978CNV Loss21882294
    dgv2529n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing BAIAP3
    DNA2.0 Custom Variant and Variant Library Synthesis for BAIAP3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 604009    OMIM disorders: --


    Find genes that share disorders with BAIAP3           About GenesLikeMe

    Genetic Association Database (GAD): BAIAP3

    Export disorders for BAIAP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for BAIAP3 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with BAIAP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1. (PubMed id 9790924)1, 2, 3, 9 Shiratsuchi T.... Nakamura Y. (Biochem. Biophys. Res. Commun. 1998)
    2. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (Nature 2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (DNA Res. 2002)
    5. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)1, 2 Daniels R.J....Higgs D.R. (Hum. Mol. Genet. 2001)
    6. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2 Nagase T.... Ohara O. (DNA Res. 1998)
    7. Genetic markers of a Munc13 protein family member, BAIAP3, are gender specifically associated with anxiety and benzodiazepine abuse in mice and humans. (PubMed id 23698091)1 Wojcik S.M....Ehrenreich H. (Mol. Med. 2013)
    8. A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. (PubMed id 17434096)4 MatarA-n M....Meschia J.F. (Lancet Neurol 2007)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    10. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (Nucleic Acids Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 8938 HGNC: 948 AceView: BAIAP3 Ensembl:ENSG00000007516 euGenes: HUgn8938
    ECgene: BAIAP3 Kegg: 8938 H-InvDB: BAIAP3

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA0734

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for BAIAP3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for BAIAP3 gene:
    Search GeneIP for patents involving BAIAP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for BAIAP3   OriGene RNAi products in human, mouse, rat for BAIAP3  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for BAIAP3  
     OriGene MassSpec for BAIAP3   OriGene clones in human, mouse for BAIAP3  
     OriGene qSTAR qPCR primer pairs in human, mouse for BAIAP3   OriGene Purified Protein for BAIAP3  
     OriGene ORF clones in mouse, rat for BAIAP3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for BAIAP3   OriGene Custom Protein Services for BAIAP3  

     
     
     Block miRNA regulation of human, mouse, rat BAIAP3 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing BAIAP3
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BAIAP3 Predesigned siRNA for gene silencing in human, mouse, rat BAIAP3
     QuantiFast Probe-based Assays in human, mouse, rat BAIAP3 QuantiTect SYBR Green Assays in human, mouse, rat BAIAP3
     Custom PCR Arrays for BAIAP3 Search Chromatin IP Primers for BAIAP3
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat BAIAP3  GeneGlobe Interaction Network for BAIAP3
     Regulatory tfbs in BAIAP3 promoter
     GenScript Custom Purified and Recombinant Proteins Services for BAIAP3 GenScript cDNA clones with any tag delivered in your preferred vector for BAIAP3
     GenScript Custom Assay Services for BAIAP3 GenScript Custom overexpressing Cell Line Services for BAIAP3
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for BAIAP3 (BAIP3)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     BAIAP3 antibodies
     BAIAP3 proteins
     BAIAP3 lysates
     Antibodies for BAIAP3
     See all of Abcam's Antibodies, Kits and Proteins for BAIAP3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for BAIAP3
     Antibodies for BAIAP3
     ELISAs for BAIAP3
     CLIAs for BAIAP3



     Browse ESI BIO Cell Lines and PureStem Progenitors for BAIAP3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BAIAP3
     SwitchGear 3'UTR luciferase reporter plasmids for BAIAP3
     SwitchGear Promoter luciferase reporter plasmids for BAIAP3
     ThermoFisher Antibodies for BAIAP3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BAIAP3
     Browse compounds at ApexBio
     Search Addgene for plasmids for BAIAP3
      Search eBioscience for proteins for BAIAP3
      Search eBioscience for elisas for BAIAP3
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for BAIAP3
     antibodies-online antibodies for BAIAP3 (32 products)
     antibodies-online kits for BAIAP3 (4 products)
     antibodies-online peptides for BAIAP3
     antibodies-online proteins for BAIAP3 (2 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      BAIAP3 gene at Home site.
    Version: 3.12.250 16 Nov 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4