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BAIAP2L2 Gene

protein-coding   GIFtS: 46
GCID: GC22M038480

BAI1-Associated Protein 2-Like 2

  Search for BAIAP2L2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
BAI1-Associated Protein 2-Like 21 2
Planar Intestinal- And Kidney-Specific BAR Domain Protein2 3
BAI1-Associated Protein 2-Like Protein 22 3
Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2-Like Protein
22
pinkbar2
Pinkbar3

External Ids:    HGNC: 262031   Entrez Gene: 801152   Ensembl: ENSG000001282987   UniProtKB: Q6UXY13   

Export aliases for BAIAP2L2 gene to outside databases

Previous GC identifers: GC22M036806 GC22M021445


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BAIAP2L2 Gene:
The protein encoded by this gene binds phosphoinositides and promotes the formation of planar or curved membrane
structures. The encoded protein is found in RAB13-positive vesicles and at intercellular contacts with the plasma
membrane. (provided by RefSeq, Dec 2012)

GeneCards Summary for BAIAP2L2 Gene:
BAIAP2L2 (BAI1-associated protein 2-like 2) is a protein-coding gene. GO annotations related to this gene include phospholipid binding and cytoskeletal adaptor activity. An important paralog of this gene is BAIAP2.

UniProtKB/Swiss-Prot: BI2L2_HUMAN, Q6UXY1
Function: Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane
structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2)
headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000022.11  NT_011520.13  NC_018933.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the BAIAP2L2 gene promoter:
         Elk-1   USF1   Pax-5   GCNF   MyoD   AP-2gamma   USF-1   NF-kappaB2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBAIAP2L2 promoter sequence
   Search Chromatin IP Primers for BAIAP2L2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BAIAP2L2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1   Ensembl cytogenetic band:  22q13.1   HGNC cytogenetic band: 22q13.1

BAIAP2L2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BAIAP2L2 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M038480:  view genomic region     (about GC identifiers)

Start:
38,480,896 bp from pter      End:
38,506,677 bp from pter
Size:
25,782 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: BI2L2_HUMAN, Q6UXY1 (See protein sequence)
Recommended Name: Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2  
Size: 529 amino acids; 58987 Da
Secondary accessions: B0QYE2 Q96BG7
Alternative splicing: 2 isoforms:  Q6UXY1-1   Q6UXY1-2   

Explore the universe of human proteins at neXtProt for BAIAP2L2: NX_Q6UXY1

Explore proteomics data for BAIAP2L2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See BAIAP2L2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079321.3  
    ENSEMBL proteins: 
     ENSP00000371085   ENSP00000410074   ENSP00000328876  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR001452 SH3_domain
     IPR013606 IRSp53/MIM_homology_IMD
     IPR027681 BAIAP2

    Graphical View of Domain Structure for InterPro Entry Q6UXY1

    ProtoNet protein and cluster: Q6UXY1

    3 Blocks protein domains:
    IPB001452 SH3 domain signature
    IPB011511 Variant SH3
    IPB013606 IRSp53/MIM homology domain


    UniProtKB/Swiss-Prot: BI2L2_HUMAN, Q6UXY1
    Domain: The IMD domain consisting of an antiparallel dimer of three-helix bundles, featuring on one side a
    positively charged. The N-terminal alpha-helix inserts into the lipid bilayer. Also forms homodimers and
    homooligomers. The residue Trp-141 is essential for oligomer formation (By similarity)
    Similarity: Contains 1 IMD (IRSp53/MIM homology) domain
    Similarity: Contains 1 SH3 domain


    BAIAP2L2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BI2L2_HUMAN, Q6UXY1
    Function: Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane
    structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2)
    headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0005543phospholipid binding ISS--
    GO:0008093cytoskeletal adaptor activity IEA--
    GO:0017124SH3 domain binding IEA--
         
    BAIAP2L2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for BAIAP2L2:
     Synthetic lethal with Ras 

         1 MGI phenotypic allele for Baiap2l2 (no phenotypes)

    BAIAP2L2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BAIAP2L2
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    hsa-miR-612 hsa-miR-520d-5p hsa-miR-524-5p hsa-miR-1285
    SwitchGear 3'UTR luciferase reporter plasmidBAIAP2L2 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BI2L2_HUMAN, Q6UXY1: Cell membrane; Peripheral membrane protein. Cell junction. Cytoplasmic vesicle membrane.
    Note=Localizes to RAB13-positive vesicles and to the plasma membrane at intercellular contacts
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    nucleus3
    cytosol2
    mitochondrion1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0012506vesicle membrane IDA--
    GO:0030659cytoplasmic vesicle membrane IEA--
    GO:0044291cell-cell contact zone IDA--
    GO:0071439colocalizes with clathrin complex IDA--

    BAIAP2L2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for BAIAP2L2
    Interactions:

        Search GeneGlobe Interaction Network for BAIAP2L2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for BAIAP2L2 (ENSP000003710854) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000237344ENSP000003971774STRING: ENSP00000397177
    HDAC3ENSP000003029674STRING: ENSP00000302967
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction IEA--
    GO:0032956regulation of actin cytoskeleton organization IEA--
    GO:0046847filopodium assembly IEA--
    GO:0061024membrane organization ISS--

    BAIAP2L2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BAIAP2L2 (BI2L2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for BAIAP2L2 gene: 
    NM_025045.5  

    Unigene Cluster for BAIAP2L2:

    BAI1-associated protein 2-like 2
    Hs.474822  [show with all ESTs]
    Unigene Representative Sequence: NM_025045
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000381669(uc003auv.3 uc003auw.3) ENST00000428572 ENST00000332536

    miRNA
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    hsa-miR-612 hsa-miR-520d-5p hsa-miR-524-5p hsa-miR-1285
    SwitchGear 3'UTR luciferase reporter plasmidBAIAP2L2 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat BAIAP2L2
      QuantiFast Probe-based Assays in human, mouse, rat BAIAP2L2

    Additional mRNA sequence: 

    AK026263.1 AY358164.1 

    6 DOTS entries:

    DT.95158759  DT.410083  DT.97789625  DT.97837824  DT.97785799  DT.91881002 

    Selected AceView cDNA sequences (see all 46):

    AI732208 AY358164 AK026263 BM790083 AA974880 AW661906 BM793696 BX281686 
    BQ948702 BI759003 AI679197 BI861483 BI819818 BG030320 BM128573 BM050416 
    BG576439 CK819409 BU185166 BM018178 AA570148 BG750736 AA877116 D25690 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for BAIAP2L2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b
    SP1:                                                                                          
    SP2:                                                                          -               
    SP3:                                                                                          
    SP4:                                                                                          


    ECgene alternative splicing isoforms for BAIAP2L2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BAIAP2L2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCTCTCTGT
    BAIAP2L2 Expression
    About this image


    BAIAP2L2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Bone (Muscoskeletal System)
             Chondrocytes Zeugopod Epiphyseal End
     
     Cartilage (Muscoskeletal System)
             Chondrocytes Zeugopod Epiphyseal End
     
     Colon (Gastrointestinal Tract)
    BAIAP2L2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BAIAP2L2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.474822

    UniProtKB/Swiss-Prot: BI2L2_HUMAN, Q6UXY1
    Tissue specificity: Expressed in the epithelial layer of the intestine (at protein level)

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for BAIAP2L2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Baiap2l21 , 5 BAI1-associated protein 2-like 21, 5 88.61(n)1
    92.13(a)1
      15 (37.70 cM)5
    2074951  NM_177580.31  NP_808248.11 
     792581955 
    chicken
    (Gallus gallus)
    Aves BAIAP2L26
    BAI1-associated protein 2-like 2
    53(a)
    1 ↔ 1
    1(50856306-50864314)
    lizard
    (Anolis carolinensis)
    Reptilia BAIAP2L26
    BAI1-associated protein 2-like 2
    62(a)
    1 ↔ 1
    GL343460.1(300456-326685)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.196872 Xenopus laevis transcribed sequence with weak similarity more 72.51(n)    CA973430.1 
    zebrafish
    (Danio rerio)
    Actinopterygii baiap2l21 BAI1-associated protein 2-like 2 52.09(n)
    48.91(a)
      564798  NM_001080804.1  NP_001074273.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG320826
    --
    11(a)
    1 → many
    3L(11129149-11157084)


    ENSEMBL Gene Tree for BAIAP2L2 (if available)
    TreeFam Gene Tree for BAIAP2L2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for BAIAP2L2 gene
    BAIAP22  BAIAP2L12  
    2 SIMAP similar genes for BAIAP2L2 using alignment to 3 protein entries:     BI2L2_HUMAN (see all proteins):
    BAIAP2    BAIAP2L1

    BAIAP2L2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BAIAP2L2 (see all 782)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1139583411,2
    F--22397403(+) CCCCAG/ACGGTT 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs1380770431,2
    C--22397410(+) GTTCT-/AATC  
            
    AATCA
    1 -- ds50010--------
    rs1873737381,2
    --22397416(+) AATCAC/TCTCAG 1 -- ds50010--------
    rs734219101,2
    C,F--22397507(+) AATCCG/ACGCCT 1 -- ds50011Minor allele frequency- A:0.50WA 2
    rs2001428351,2
    C--22397527(+) AATGT-/GGGGGG 1 -- ds50010--------
    rs794922521,2
    F--22397614(+) CTGCCA/GCCTCT 1 -- ds50012Minor allele frequency- G:0.18CSA WA 119
    rs1443051891,2
    C--22397623(+) CTCCC-/CTGACCC 1 -- ds50010--------
    rs22673661,2
    C,F,H--22397640(+) GCCGCT/CACTTC 1 -- ds500120Minor allele frequency- C:0.20EA NS NA CSA WA 4010
    rs795703131,2
    F--22397659(+) CCCACA/GGGTCG 1 -- ds50011Minor allele frequency- G:0.03WA 118
    rs1898586751,2
    C--22397675(+) AGAGCA/CGGTGG 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for BAIAP2L2 (38480896 - 38506677 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for BAIAP2L2 (see all 15):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2724223CNV Deletion23290073
    nsv3623CNV Insertion18451855
    esv996111CNV Insertion20482838
    nsv508732CNV Insertion20534489
    esv1386806CNV Insertion17803354
    nsv513591CNV Insertion21212237
    nsv915053CNV Loss21882294
    nsv834193CNV Loss17160897
    nsv829205CNV Loss20364138
    nsv834194CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BAIAP2L2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with BAIAP2L2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    3. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I.... Wright H. (Nature 1999)
    4. Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures. (PubMed id 21743456)2 Pykalainen A.... Lappalainen P. (Nat. Struct. Mol. Biol. 2011)
    5. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 80115 HGNC: 26203 AceView: FLJ22582 Ensembl:ENSG00000128298 euGenes: HUgn80115
    ECgene: BAIAP2L2 H-InvDB: BAIAP2L2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BAIAP2L2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BAIAP2L2 gene:
    Search GeneIP for patents involving BAIAP2L2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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