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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BAI1 Gene

protein-coding   GIFtS: 60
GCID: GC08P143542

brain-specific angiogenesis inhibitor 1

 Explore 6 diseases affiliated with
BAI1 via our new
 Human Malady Compendium 
Biological research products
for BAI1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Brain-Specific Angiogenesis Inhibitor 11 2
GDAIF2

External Ids:    HGNC: 9431   Entrez Gene: 5752   Ensembl: ENSG000001817907   OMIM: 6026825   UniProtKB: O145143   

Export aliases for BAI1 gene to outside databases

Previous GC identifers: GC08U990005 GC08P143719 GC08P143189 GC08P143444 GC08P138802


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for BAI1:
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed
under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid
tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels
as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1
contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced
by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along
with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53.
BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth
suppressor of glioblastomas (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: BAI1_HUMAN, O14514
Function: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor
of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of
glioblastoma. May function in cell adhesion and signal transduction in the brain

Gene Wiki entry for BAI1 (Brain-specific angiogenesis inhibitor 1)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.1  NT_008046.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the BAI1 gene promoter:
         AREB6   HEN1   NRSF form 1   MyoD   NRSF form 2   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBAI1 promoter sequence
   Search SABiosciences Chromatin IP Primers for BAI1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BAI1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.3   Ensembl cytogenetic band:  8q24.3   HGNC cytogenetic band: 8q24.3

BAI1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BAI1 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P143542:  view genomic region     (about GC identifiers)

Start:
143,530,791 bp from pter      End:
143,626,370 bp from pter
Size:
95,580 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: BAI1_HUMAN, O14514 (See protein sequence)
Recommended Name: Brain-specific angiogenesis inhibitor 1 precursor  
Size: 1584 amino acids; 173501 Da
Subunit: Interacts with ELMO1 and DOCK1. When bound to ELMO1 and DOCK1, it may act as a module to promote the
engulfment (By similarity). Interacts with MAGI1, MAGI3, BAIAP2 and PHYHIP
Subcellular location: Cell membrane; Multi-pass membrane protein. Note=Likely to be concentrated at cell-cell adhesion
sites

Explore the universe of human proteins at neXtProt for BAI1: NX_O14514

Post-translational modifications:

  • The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane
  • subunit1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O14514

  • BAI1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001693.2  
    ENSEMBL proteins: 
     ENSP00000430945   ENSP00000427783   ENSP00000313046  

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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for BAI1

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS9647739
    GO:0005887integral to plasma membrane TAS9647739
    GO:0005911cell-cell junction TAS9647739
    GO:0016021integral to membrane TAS15203201


    BAI1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    BAI1 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR000884 Thrombospondin_1_rpt
     IPR008077 GPCR_2_brain-spec_angio_inhib
     IPR001879 GPCR_2_extracellular_dom
     IPR017981 GPCR_2-like
     IPR022624 DUF3497

    Graphical View of Domain Structure for InterPro Entry O14514

    ProtoNet protein and cluster: O14514

    5 Blocks protein families:
    IPB000203 GPS domain
    IPB000832 G-protein coupled receptors family 2 (secretin-like)
    IPB000884 Thrombospondin
    IPB008077 Brain-specific angiogenesis inhibitor precursor signature
    IPB008085 Thrombospondin type 1 repeat signature


    UniProtKB/Swiss-Prot: BAI1_HUMAN, O14514
    Domain: The TSP1 repeats inhibit in vivo angiogenesis in rat cornea induced by BFGF
    Similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily
    Similarity: Contains 1 GPS domain
    Similarity: Contains 5 TSP type-1 domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: BAI1_HUMAN, O14514
    Function: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor
    of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of
    glioblastoma. May function in cell adhesion and signal transduction in the brain
    Induction: By p53/TP53

         Genatlas biochemistry entry for BAI1:
    brain specific angiogenesis inhibitor 1,induced by TP53,expressed in brain,suppressor of glioblastoma family

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat BAI1
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    hsa-miR-15a hsa-miR-424 hsa-miR-2115 hsa-miR-149 hsa-miR-376a* hsa-miR-3121-3p hsa-miR-195 hsa-miR-1914
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity IEA--
    GO:0005515protein binding ----


    BAI1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for BAI1:
     Increased gamma-H2AX phosphory 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1p53 signaling pathway
    p53 signaling pathway1.00
    2Selected targets of p53
    Selected targets of p531.00
    3Chks in Checkpoint Regulation
    p53 Signaling0.32

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for BAI1
        Selected targets of p53

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for BAI1
        p53 Signaling


    1         Kegg Pathway  (Kegg details for BAI1):
        p53 signaling pathway


    BAI1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BAI1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/8 Interacting proteins for BAI1 (O145142, 3 ENSP000003130464) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAGI3Q5TCQ92, 3, ENSP000003046044MINT-1796764 MINT-72930 I2D: score=4 STRING: ENSP00000304604
    DLG4P783523, ENSP000002938134I2D: score=2 STRING: ENSP00000293813
    EIF3HO153723, ENSP000002766824I2D: score=2 STRING: ENSP00000276682
    BAIAP2Q9UQB83, ENSP000003163384I2D: score=1 STRING: ENSP00000316338
    BAIAP3O948123, ENSP000003245104I2D: score=3 STRING: ENSP00000324510
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion IEA--
    GO:0007165signal transduction TAS9647739
    GO:0007186G-protein coupled receptor signaling pathway TAS15203201
    GO:0007218neuropeptide signaling pathway IEA--
    GO:0007409axonogenesis TAS10343108


    BAI1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BAI1
    Search CenterWatch for drugs/clinical trials and news about BAI1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BAI1 gene: 
    NM_001702.2  

    Unigene Cluster for BAI1:

    Brain-specific angiogenesis inhibitor 1
    Hs.194654  [show with all ESTs]
    Unigene Representative Sequence: NM_001702
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000517894(uc003ywm.3) ENST00000521208 ENST00000518820 ENST00000518812
    ENST00000323289

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    hsa-miR-15a hsa-miR-424 hsa-miR-2115 hsa-miR-149 hsa-miR-376a* hsa-miR-3121-3p hsa-miR-195 hsa-miR-1914
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    Inhib. RNA
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    Additional cDNA sequence: 

    AB005297.1 AK123982.1 

    3 DOTS entries:

    DT.208672  DT.101967103  DT.86840585 

    24/32 AceView cDNA sequences (see all 32):

    BG912470 AW117944 AB005297 NM_001702 AK123982 BF527323 BG819644 AI151122 
    BG680852 BF515543 BG819770 AI366534 BG911746 BU146414 D60158 BF514070 
    AI608632 AW165986 D61109 D61322 D80904 D60514 CD579693 BF850310 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BAI1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCCCCCAGGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    BAI1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Definitive endoderm-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See BAI1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BAI1

    SOURCE GeneReport for Unigene cluster: Hs.194654

    UniProtKB/Swiss-Prot: BAI1_HUMAN, O14514
    Tissue specificity: Specifically expressed in brain. Reduced or no expression is observed in some glioblastoma cell
    lines and cancer tissues. No expression in astrocytes

        SABiosciences Expression via Pathway-Focused PCR Arrays including BAI1: 
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              Angiogenic Growth Factors in human mouse rat
              p53 Signaling Pathway in human mouse rat
              Angiogenesis in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BAI1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for BAI1 gene from 4/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves LOC1008597551 brain-specific angiogenesis inhibitor 1-like 74.16(n)
    79.5(a)
      100859755  XM_003640860.1  XP_003640908.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    --
    79(a)
    71(a)
    1 ↔ many
    1 ↔ many
    GL343222.1(1755656-1811062)
    GL343222.1(1505169-1644776)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.152372 Transcribed sequence with moderate similarity to protein more 77.5(n)    BM185566.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T21B6.36
    F14H12.36
    Protein F14H12.3
    8(a)
    22(a)
    possible ortholog
    1 ↔ many
    X(10945088-10948904)
    X(4344227-4345626)


    ENSEMBL Gene Tree for BAI1 (if available)
    TreeFam Gene Tree for BAI1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BAI1 gene
    UNC5B2  UNC5C2  UNC5A2  UNC5CL2  CFP2  BAI32  BAI22  UNC5D2  
    3 SIMAP similar genes for BAI1 using alignment to 2 protein entries:     BAI1_HUMAN (see all proteins):
    BAI3    ELTD1    BAI2

    BAI1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1454 NCBI SNPs in BAI1 are shown (see all 1454    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1116705581,2
    C,--138821549(+) TACACA/CCTGAA 1 -- int10--------
    rs765992881,2
    C,F,--143543574(+) GAGCCC/TGGAAT 1 -- us2k13Minor allele frequency- T:0.15CSA WA 122
    rs1900034401,2
    --143543588(+) TGCCAC/GGAATG 1 -- us2k10--------
    rs1811815071,2
    --143543659(+) TCCTCC/TCCCTG 1 -- us2k10--------
    rs1855401651,2
    --143543827(+) GCCCAA/GGTCCA 1 -- us2k10--------
    rs1504729561,2
    --143543928(+) CCTACA/CAGGCT 1 -- us2k10--------
    rs1382899501,2
    --143544025(+) AAGTCC/TCGTGG 1 -- us2k10--------
    rs1159110931,2
    F,--143544064(+) AGAGCG/AGAGGC 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1496146431,2
    --143544181(+) CCTTGC/GGGGTG 1 -- us2k10--------
    rs1144525041,2
    F,--143544270(+) GCCCCG/CGATCC 1 -- us2k11Minor allele frequency- C:0.03WA 118

    HapMap Linkage Disequilibrium report for BAI1 (143530791 - 143626370 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 7 variations for BAI1
         3 CNVs: 2778 30295 30296
         4 Indels: 47492 62869 62868 47491

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BAI1
    DNA2.0 Custom Variant and Variant Library Synthesis for BAI1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    BAI1 for disorders           About GeneDecksing

    OMIM gene information: 602682    OMIM disorders: --

    6 diseases for BAI1:    About MalaCards
    glioblastoma    gastric cancer    colorectal cancer    cerebritis
    adenocarcinoma    neuronitis

    6 Novoseek disease relationships for BAI1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glioblastoma 63.2 9 16244591 (4), 16796906 (2), 9533023 (1), 12507886 (1)
    tumors 19.9 6 16244591 (1), 19910109 (1), 11172604 (1)
    gastric cancer 19.8 2 17374440 (1), 11172604 (1)
    colorectal cancer 11.8 5 9772287 (4), 10568831 (1)
    metastasis 3.44 3 9772287 (2), 11172604 (1)
    cancer 3.24 1 10568831 (1)


    Export disorders for BAI1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BAI1 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with BAI1)
        Utopia: connect your pdf to the dynamic
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    1. Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1. (PubMed id 10343108)1, 2, 9 Oda K.... Tokino T. (1999)
    2. Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1. (PubMed id 9647739)1, 2, 9 Shiratsuchi T....Tokino T. (1998)
    3. Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1). (PubMed id 9533023)1, 3, 9 Shiratsuchi T.... Tokino T. (1997)
    4. Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression. (PubMed id 12507886)1, 2, 9 Kaur B.... Van Meir E.G. (2003)
    5. Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis. (PubMed id 11875720)1, 2 Duda D.G.... Matsuno S. (2002)
    6. Brain-specific angiogenesis inhibitor 1 (BAI1) is expressed in human cerebral neuronal cells. (PubMed id 12074842)1, 2 Mori K.... Arita N. (2002)
    7. Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase. (PubMed id 10748157)1, 2 Wu Y.... Lasky L.A. (2000)
    8. A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesis. (PubMed id 9393972)1, 2 Nishimori H.... Tokino T. (1997)
    9. Characterization of mouse brain-specific angiogenesis inhibitor 1 (BAI1) and phytanoyl-CoA alpha-hydroxylase-associated protein 1, a novel BAI1-binding protein. (PubMed id 11245925)1, 9 Koh J.T....Kim K.K. (2001)
    10. Extracellular fragment of brain-specific angiogenesis inhibitor 1 suppresses endothelial cell proliferation by blocking alphavbeta5 integrin. (PubMed id 14980512)1, 9 Koh J.T....Kim K.K. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 575 HGNC: 943 AceView: BAI1 Ensembl:ENSG00000181790 euGenes: HUgn575
    ECgene: BAI1 Kegg: 575 H-InvDB: BAI1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BAI1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BAI1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BAI1 gene:
    Search GeneIP for patents involving BAI1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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