Free for academic non-profit institutions. Other users need a Commercial license

Aliases for BAGE5 Gene

Aliases for BAGE5 Gene

  • B Melanoma Antigen Family Member 5 5 2 3
  • B Melanoma Antigen Family, Member 5 2 3
  • Cancer/Testis Antigen 2.5 3 4
  • CT2.5 3 4
  • Cancer/Testis Antigen Family 2, Member 5 3
  • Cancer/Testis Antigen Family 2 2
  • Member 5 2

External Ids for BAGE5 Gene

Previous GeneCards Identifiers for BAGE5 Gene

  • GC13U990073
  • GC21M010120
  • GC21M010046
  • GC21M010073
  • GC21M010074
  • GC21M010998
  • GC07M151833
  • GC00M8E0002

Summaries for BAGE5 Gene

GeneCards Summary for BAGE5 Gene

BAGE5 (B Melanoma Antigen Family Member 5) is a Protein Coding gene.

UniProtKB/Swiss-Prot for BAGE5 Gene

  • Unknown. Candidate gene encoding tumor antigens.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BAGE5 Gene

Genomics for BAGE5 Gene

Regulatory Elements for BAGE5 Gene

Enhancers for BAGE5 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around BAGE5 on UCSC Golden Path with GeneCards custom track

Genomic Location for BAGE5 Gene

Chromosome:
22
Start:
11,066,501 bp from pter
End:
11,068,089 bp from pter
Size:
1,589 bases
Orientation:
Plus strand

Genomic View for BAGE5 Gene

Genes around BAGE5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BAGE5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BAGE5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for BAGE5 Gene

Proteins for BAGE5 Gene

  • Protein details for BAGE5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86Y27-BAGE5_HUMAN
    Recommended name:
    B melanoma antigen 5
    Protein Accession:
    Q86Y27

    Protein attributes for BAGE5 Gene

    Size:
    43 amino acids
    Molecular mass:
    4711 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the KMT2C/MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21.

neXtProt entry for BAGE5 Gene

Proteomics data for BAGE5 Gene at MOPED

Post-translational modifications for BAGE5 Gene

No Post-translational modifications

Other Protein References for BAGE5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for BAGE5 Gene

Domains & Families for BAGE5 Gene

Protein Domains for BAGE5 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for BAGE5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q86Y27

UniProtKB/Swiss-Prot:

BAGE5_HUMAN :
  • Belongs to the BAGE family.
Family:
  • Belongs to the BAGE family.
genes like me logo Genes that share domains with BAGE5: view

No data available for Gene Families for BAGE5 Gene

Function for BAGE5 Gene

Molecular function for BAGE5 Gene

UniProtKB/Swiss-Prot Function:
Unknown. Candidate gene encoding tumor antigens.

Phenotypes for BAGE5 Gene

GenomeRNAi human phenotypes for BAGE5:
genes like me logo Genes that share phenotypes with BAGE5: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for BAGE5 Gene

Localization for BAGE5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BAGE5 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for BAGE5 Gene COMPARTMENTS Subcellular localization image for BAGE5 gene
Compartment Confidence
extracellular 3

No data available for Gene Ontology (GO) - Cellular Components for BAGE5 Gene

Pathways & Interactions for BAGE5 Gene

SuperPathways for BAGE5 Gene

No Data Available

Interacting Proteins for BAGE5 Gene

Gene Ontology (GO) - Biological Process for BAGE5 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BAGE5 Gene

Drugs & Compounds for BAGE5 Gene

No Compound Related Data Available

Transcripts for BAGE5 Gene

mRNA/cDNA for BAGE5 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for BAGE5 Gene

No ASD Table

Relevant External Links for BAGE5 Gene

GeneLoc Exon Structure for
BAGE5
ECgene alternative splicing isoforms for
BAGE5

Expression for BAGE5 Gene

mRNA Expression by UniProt/SwissProt for BAGE5 Gene

Q86Y27-BAGE5_HUMAN
Tissue specificity: Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas.

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for BAGE5 Gene

Orthologs for BAGE5 Gene

Evolution for BAGE5 Gene

ENSEMBL:
Gene Tree for BAGE5 (if available)
TreeFam:
Gene Tree for BAGE5 (if available)

No data available for Orthologs for BAGE5 Gene

Paralogs for BAGE5 Gene

(4) SIMAP similar genes for BAGE5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with BAGE5: view

No data available for Paralogs for BAGE5 Gene

Variants for BAGE5 Gene

Structural Variations from Database of Genomic Variants (DGV) for BAGE5 Gene

Variant ID Type Subtype PubMed ID
esv28756 CNV Gain+Loss 19812545
nsv428382 CNV Gain+Loss 18775914
dgv712n67 CNV Gain 20364138
esv32564 CNV Gain+Loss 17666407
esv29976 CNV Gain 17803354
nsv437841 CNV Loss 16327808
dgv1349e1 CNV Complex 17122850
esv720 CNV CNV 17122850
esv1000174 CNV Deletion 20482838
nsv436336 CNV Deletion 17901297
nsv512628 CNV Loss 21212237
esv2661615 CNV Deletion 23128226
esv991443 OTHER Inversion 20482838
nsv828817 CNV Gain 20364138
nsv469643 CNV Loss 16826518
dgv1350e1 CNV Complex 17122850
nsv834041 CNV Gain 17160897
nsv9838 CNV Gain+Loss 18304495
nsv820736 CNV Duplication 20802225
esv1008267 CNV Deletion 20482838
esv9537 CNV Loss 19470904
esv987944 CNV Deletion 20482838
nsv819478 CNV Gain 19587683
esv1008615 CNV Deletion 20482838
nsv828818 CNV Gain 20364138
nsv471421 CNV Duplication 19718026
esv1001067 CNV Insertion 20482838
nsv512629 CNV Loss 21212237
esv7291 CNV Loss 19470904
esv2563009 CNV Deletion 19546169
esv2675165 CNV Deletion 23128226
nsv435743 CNV Deletion 17901297
esv2474693 CNV Deletion 19546169
nsv436329 CNV Deletion 17901297
esv999403 CNV Deletion 20482838
nsv498974 CNV Loss 21111241
nsv3451 CNV Insertion 18451855
dgv73n16 CNV Deletion 17901297
nsv512630 CNV Loss 21212237
esv999554 CNV Insertion 20482838
esv1002199 CNV Deletion 20482838

Relevant External Links for BAGE5 Gene

HapMap Linkage Disequilibrium report
BAGE5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for BAGE5 Gene

Disorders for BAGE5 Gene

Relevant External Links for BAGE5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
BAGE5

No disorders were found for BAGE5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BAGE5 Gene

Publications for BAGE5 Gene

  1. BAGE genes generated by juxtacentromeric reshuffling in the hominidae lineage are under selective pressure. (PMID: 12676563) Ruault M. … De Sario A. (Genomics 2003) 2 3 4 67
  2. New BAGE (B melanoma antigen) genes mapping to the juxtacentromeric regions of human chromosomes 13 and 21 have a cancer/testis expression profile. (PMID: 12461691) Ruault M. … De Sario A. (Eur. J. Hum. Genet. 2002) 2 3
  3. BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes. (PMID: 7895173) Boel P. … van der Bruggen P. (Immunity 1995) 3

Products for BAGE5 Gene

Sources for BAGE5 Gene

Content