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Aliases & Descriptions for BAGE4
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| CT2.4 1, 2, 3 | | MGC119851 2 | | MGC119852 2 | | MGC119853 2 | | MLL3P 2, 3 |
| | | Descriptions |
|---|
| B melanoma antigen family, member 4 2 | | Cancer/testis antigen 2.4 3 | | MLL3 pseudogene 1, 2 | | cancer/testis antigen family 2, member 4 2 |
|
| | Search outside databases for aliases for BAGE4 genePrevious GC identifers: GC00U991011 GC21M010119 GC21M010045 GC07M151364 GC21M010048 GC21M010049 |
Summaries for BAGE4(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: BAGE4_HUMAN, Q86Y28Function: Unknown. Candidate gene encoding tumor antigens |
Genomic Location for BAGE4
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the BAGE4 gene 
Entrez Gene cytogenetic band: 21p11.1 Ensembl cytogenetic band: 21p11.1 HGNC cytogenetic band: 21p11.1BAGE4 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 21 GeneLoc Exon Structure GeneLoc location for GC21M010050:
(about GC identifiers)
Start:
|
10,042,713 bp from pter |
End:
|
10,120,796 bp from pter |
Size:
|
78,084 bases |
Orientation:
|
minus strand |
| Proteins for BAGE4
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: BAGE4_HUMAN, Q86Y28 (See
protein sequence)Recommended Name: B melanoma antigen 4 precursor Size: 39 amino acids; 4230 Da
Subcellular location: Secreted (Potential)
Miscellaneous: The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21REFSEQ proteins: NP_859055.1
ENSEMBL proteins: ENSP00000349289 ENSP00000335528
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
1 Gene Ontology (GO) cellular component term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- | About this table
Antibodies for BAGE4: Assays for BAGE4: | Protein
Domains/ Families for BAGE4(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q86Y28
ProtoNet protein and cluster: Q86Y28 1 Blocks protein family: IPB012530 B melanoma antigen
UniProtKB/Swiss-Prot: BAGE4_HUMAN, Q86Y28Similarity: Belongs to the BAGE family | Gene Function for BAGE4
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_181704
Applied Biosystems Silencer® siRNAs for BAGE4
Sigma-Aldrich siRNA for BAGE4  Sigma-Aldrich shRNA for BAGE4  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_181704                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_181704                                  untagged cDNA clone in CMV expression vector: NM_181704 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_181704
UniProtKB/Swiss-Prot: BAGE4_HUMAN, Q86Y28Function: Unknown. Candidate gene encoding tumor antigens | Pathways & Interactions for BAGE4
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
5/21 Interacting proteins for BAGE4 (ENSP000003355283) via UniProtKB, MINT, and/or STRING (see all 21
)About this table
|
Drugs & Compounds for BAGE4(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for BAGE4
|
Transcripts for BAGE4(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_181704
Sigma-Aldrich siRNA for BAGE4  Sigma-Aldrich shRNA for BAGE4  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_181704 REFSEQ mRNAs for BAGE4 gene: NM_181704.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_181704               OriGene GFP tagged cDNA clone in CMV expression vector: NM_181704                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_181704                                  untagged cDNA clone in CMV expression vector: NM_181704  24/366 AceView cDNA sequences (see all 366
):AI079937 AV723842 AA116096 AA904721 BX645616 AI468635 BQ434831 BM453753 BQ890802 AI275540 BM509873 AA737189 BM910422 AA236552 AI362634 AI915942 CD513584 AI540051 BF949197 BM126876 AI681382 AW864964 AI640514 CF272338
highest scoring ESTs for BAGE4:AF339515 AF339516 BE084888 NM_181704 NM_182484
GeneLoc Exon Structure
2 Ensembl transcripts including schematic representations: ENST00000356832
ENST00000335369
|
Expression for BAGE4
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| BAGE4 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for BAGE4
/ 2 / 3 2 probe-sets matching BAGE4 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: -- UniProtKB/Swiss-Prot: BAGE4_HUMAN, Q86Y28Tissue specificity: Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas |
Orthologs for BAGE4
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for BAGE4 | Paralogs for BAGE4(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| -- |
SNPs/Variants for BAGE4(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for BAGE4 (up to first 250kb)
|
Disorders & Mutations for BAGE4
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News for BAGE4(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for BAGE4 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 3 PubMed articles for BAGE4 gene: |
Search for BAGE4
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing BAGE4
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing BAGE4
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BAGE4(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for BAGE4(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for BAGE4:

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Incremental update: 13 Oct 2009
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