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Aliases for BAGE4 Gene

Aliases for BAGE4 Gene

  • B Melanoma Antigen Family Member 4 2 3
  • Cancer/Testis Antigen Family 2, Member 4 2 3
  • Cancer/Testis Antigen 2.4 3 4
  • MLL3 Pseudogene 2 3
  • MLL3P 3 4
  • CT2.4 3 4
  • B Melanoma Antigen Family, Member 4 2
  • B Melanoma Antigen Family Member 5 5
  • B Melanoma Antigen 4 3
  • BAGE5 5

External Ids for BAGE4 Gene

Previous HGNC Symbols for BAGE4 Gene

  • MLL3P

Previous GeneCards Identifiers for BAGE4 Gene

  • GC00U991011
  • GC21M010119
  • GC21M010045
  • GC07M151364
  • GC21M010048
  • GC21M010049
  • GC21M010050
  • GC21M010999
  • GC07M151834
  • GC21U900419
  • GC21M014741

Summaries for BAGE4 Gene

GeneCards Summary for BAGE4 Gene

BAGE4 (B Melanoma Antigen Family Member 4) is a Protein Coding gene.

UniProtKB/Swiss-Prot for BAGE4 Gene

  • Unknown. Candidate gene encoding tumor antigens.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BAGE4 Gene

Genomics for BAGE4 Gene

Genomic Location for BAGE4 Gene

Chromosome:
22
Start:
11,066,501 bp from pter
End:
11,068,089 bp from pter
Size:
1,589 bases
Orientation:
Plus strand

Genomic View for BAGE4 Gene

Genes around BAGE4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BAGE4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BAGE4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for Regulatory Elements and RefSeq DNA sequence for BAGE4 Gene

Proteins for BAGE4 Gene

  • Protein details for BAGE4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86Y28-BAGE4_HUMAN
    Recommended name:
    B melanoma antigen 4
    Protein Accession:
    Q86Y28

    Protein attributes for BAGE4 Gene

    Size:
    39 amino acids
    Molecular mass:
    4230 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the KMT2C/MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21.

neXtProt entry for BAGE4 Gene

Post-translational modifications for BAGE4 Gene

No Post-translational modifications

Other Protein References for BAGE4 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for BAGE4 Gene

Domains & Families for BAGE4 Gene

Protein Domains for BAGE4 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for BAGE4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q86Y28

UniProtKB/Swiss-Prot:

BAGE4_HUMAN :
  • Belongs to the BAGE family.
Family:
  • Belongs to the BAGE family.
genes like me logo Genes that share domains with BAGE4: view

No data available for Gene Families for BAGE4 Gene

Function for BAGE4 Gene

Molecular function for BAGE4 Gene

UniProtKB/Swiss-Prot Function:
Unknown. Candidate gene encoding tumor antigens.
genes like me logo Genes that share phenotypes with BAGE4: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BAGE4 Gene

Localization for BAGE4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BAGE4 Gene

Secreted.

Gene Ontology (GO) - Cellular Components for BAGE4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with BAGE4: view

No data available for Subcellular locations from COMPARTMENTS for BAGE4 Gene

Pathways & Interactions for BAGE4 Gene

SuperPathways for BAGE4 Gene

No Data Available

Interacting Proteins for BAGE4 Gene

Gene Ontology (GO) - Biological Process for BAGE4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BAGE4 Gene

Transcripts for BAGE4 Gene

mRNA/cDNA for BAGE4 Gene

(1) REFSEQ mRNAs :
(366) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for BAGE4 Gene

No ASD Table

Relevant External Links for BAGE4 Gene

GeneLoc Exon Structure for
BAGE4
ECgene alternative splicing isoforms for
BAGE4

Expression for BAGE4 Gene

mRNA expression in normal human tissues for BAGE4 Gene

mRNA expression in normal human tissues for BAGE4 Gene

NURSA nuclear receptor signaling pathways regulating expression of BAGE4 Gene:

BAGE4

mRNA Expression by UniProt/SwissProt for BAGE4 Gene:

Q86Y28-BAGE4_HUMAN
Tissue specificity: Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas.
genes like me logo Genes that share expression patterns with BAGE4: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for BAGE4 Gene

Orthologs for BAGE4 Gene

Evolution for BAGE4 Gene

ENSEMBL:
Gene Tree for BAGE4 (if available)
TreeFam:
Gene Tree for BAGE4 (if available)

No data available for Orthologs for BAGE4 Gene

Paralogs for BAGE4 Gene

(4) SIMAP similar genes for BAGE4 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with BAGE4: view

No data available for Paralogs for BAGE4 Gene

Variants for BAGE4 Gene

Structural Variations from Database of Genomic Variants (DGV) for BAGE4 Gene

Variant ID Type Subtype PubMed ID
dgv2349n106 CNV duplication 24896259
dgv2350n106 CNV deletion 24896259
dgv2351n106 CNV deletion 24896259
dgv2352n106 CNV deletion 24896259
dgv2353n106 CNV deletion 24896259
dgv2354n106 CNV deletion 24896259
dgv2468e59 CNV duplication 20981092
dgv4353n100 CNV loss 25217958
dgv4354n100 CNV gain+loss 25217958
dgv4355n100 CNV gain 25217958
dgv4356n100 CNV loss 25217958
dgv4358n100 CNV gain 25217958
dgv4363n100 CNV loss 25217958
dgv4367n100 CNV gain 25217958
dgv4368n100 CNV gain+loss 25217958
dgv4369n100 CNV gain 25217958
dgv4370n100 CNV loss 25217958
dgv4371n100 CNV gain 25217958
dgv4372n100 CNV loss 25217958
dgv4373n100 CNV gain+loss 25217958
dgv712n67 CNV gain 20364138
dgv73n16 CNV deletion 17901297
dgv7728n54 CNV gain 21841781
dgv7729n54 CNV gain 21841781
dgv7743n54 CNV gain 21841781
esv1000174 CNV deletion 20482838
esv1001067 CNV insertion 20482838
esv1002199 CNV deletion 20482838
esv1008267 CNV deletion 20482838
esv1008615 CNV deletion 20482838
esv2474693 CNV deletion 19546169
esv2563009 CNV deletion 19546169
esv2661615 CNV deletion 23128226
esv2675165 CNV deletion 23128226
esv2758808 CNV gain+loss 17122850
esv2760704 CNV gain 21179565
esv2763681 CNV gain+loss 21179565
esv28756 CNV gain+loss 19812545
esv29976 CNV gain 17803354
esv3057124 CNV deletion 24192839
esv32564 CNV gain+loss 17666407
esv3412511 CNV insertion 20981092
esv3557431 CNV deletion 23714750
esv3557434 CNV deletion 23714750
esv3646371 CNV loss 21293372
esv7291 CNV loss 19470904
esv9537 CNV loss 19470904
esv987944 CNV deletion 20482838
esv991443 OTHER inversion 20482838
esv999403 CNV deletion 20482838
esv999554 CNV insertion 20482838
nsv1057510 CNV loss 25217958
nsv1059291 CNV loss 25217958
nsv1059477 CNV gain 25217958
nsv1060052 CNV loss 25217958
nsv1064391 CNV loss 25217958
nsv1064913 CNV gain 25217958
nsv1071405 CNV deletion 25765185
nsv1071408 CNV deletion 25765185
nsv1071737 CNV deletion 25765185
nsv1071738 CNV deletion 25765185
nsv1071739 CNV deletion 25765185
nsv1071740 CNV deletion 25765185
nsv1071741 CNV deletion 25765185
nsv1072155 CNV deletion 25765185
nsv1072156 CNV deletion 25765185
nsv1072757 CNV deletion 25765185
nsv1073108 CNV deletion 25765185
nsv1073109 CNV deletion 25765185
nsv1073110 CNV deletion 25765185
nsv1073111 CNV deletion 25765185
nsv1078497 CNV duplication 25765185
nsv1109407 CNV deletion 24896259
nsv1114259 CNV deletion 24896259
nsv1116897 CNV deletion 24896259
nsv1123523 CNV deletion 24896259
nsv1123524 CNV deletion 24896259
nsv1123525 CNV deletion 24896259
nsv1136589 CNV deletion 24896259
nsv1136590 CNV deletion 24896259
nsv1136592 CNV deletion 24896259
nsv1136593 CNV deletion 24896259
nsv1138994 CNV deletion 24896259
nsv1138995 CNV deletion 24896259
nsv1138996 CNV deletion 24896259
nsv1138997 CNV deletion 24896259
nsv1143010 CNV tandem duplication 24896259
nsv1150038 CNV deletion 26484159
nsv1151660 CNV duplication 26484159
nsv3451 CNV insertion 18451855
nsv428382 CNV gain+loss 18775914
nsv435743 CNV deletion 17901297
nsv436329 CNV deletion 17901297
nsv436336 CNV deletion 17901297
nsv437841 CNV loss 16327808
nsv469643 CNV loss 16826518
nsv471421 CNV gain 19718026
nsv498974 CNV loss 21111241
nsv512628 CNV loss 21212237
nsv512629 CNV loss 21212237
nsv512630 CNV loss 21212237
nsv586978 CNV gain 21841781
nsv586979 CNV loss 21841781
nsv586980 CNV loss 21841781
nsv819478 CNV gain 19587683
nsv820736 CNV duplication 20802225
nsv828817 CNV gain 20364138
nsv828818 CNV gain 20364138
nsv834041 CNV gain 17160897
nsv953331 CNV duplication 24416366
nsv953332 CNV duplication 24416366
nsv954302 CNV deletion 24416366
nsv956736 CNV deletion 24416366
nsv964472 CNV duplication 23825009
nsv964473 CNV duplication 23825009
nsv965963 CNV duplication 23825009
nsv965965 CNV duplication 23825009
nsv965987 CNV duplication 23825009
nsv979515 CNV duplication 23825009
nsv9838 CNV gain+loss 18304495

Relevant External Links for BAGE4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
BAGE4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for BAGE4 Gene

Disorders for BAGE4 Gene

Relevant External Links for BAGE4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
BAGE4

No disorders were found for BAGE4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BAGE4 Gene

Publications for BAGE4 Gene

  1. BAGE genes generated by juxtacentromeric reshuffling in the hominidae lineage are under selective pressure. (PMID: 12676563) Ruault M. … De Sario A. (Genomics 2003) 2 3 64
  2. New BAGE (B melanoma antigen) genes mapping to the juxtacentromeric regions of human chromosomes 13 and 21 have a cancer/testis expression profile. (PMID: 12461691) Ruault M. … De Sario A. (Eur. J. Hum. Genet. 2002) 3 64
  3. BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes. (PMID: 7895173) Boel P. … van der Bruggen P. (Immunity 1995) 3 64

Products for BAGE4 Gene

Sources for BAGE4 Gene

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