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Aliases for BAGE4 Gene

Aliases for BAGE4 Gene

  • B Melanoma Antigen Family, Member 4 2 3
  • Cancer/Testis Antigen 2.4 3 4
  • MLL3 Pseudogene 2 3
  • MLL3P 3 4
  • CT2.4 3 4
  • Cancer/Testis Antigen Family 2, Member 4 3
  • Cancer/Testis Antigen Family 2 2
  • B Melanoma Antigen 4 3
  • Member 4 2

External Ids for BAGE4 Gene

Previous HGNC Symbols for BAGE4 Gene

  • MLL3P

Previous GeneCards Identifiers for BAGE4 Gene

  • GC00U991011
  • GC21M010119
  • GC21M010045
  • GC07M151364
  • GC21M010048
  • GC21M010049
  • GC21M010050
  • GC21M010999
  • GC07M151834
  • GC21M014741

Summaries for BAGE4 Gene

GeneCards Summary for BAGE4 Gene

BAGE4 (B Melanoma Antigen Family, Member 4) is a Protein Coding gene.

UniProtKB/Swiss-Prot for BAGE4 Gene

  • Unknown. Candidate gene encoding tumor antigens

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BAGE4 Gene

Genomics for BAGE4 Gene

Genomic Location for BAGE4 Gene

Orientation:
Unknown strand

Genomic View for BAGE4 Gene

Cytogenetic band:

No data available for Regulatory Elements and RefSeq DNA sequence for BAGE4 Gene

Proteins for BAGE4 Gene

  • Protein details for BAGE4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86Y28-BAGE4_HUMAN
    Recommended name:
    B melanoma antigen 4
    Protein Accession:
    Q86Y28
    Secondary Accessions:

    Protein attributes for BAGE4 Gene

    Size:
    39 amino acids
    Molecular mass:
    4230 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the KMT2C/MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21

neXtProt entry for BAGE4 Gene

Proteomics data for BAGE4 Gene at MOPED

Post-translational modifications for BAGE4 Gene

No Post-translational modifications

Other Protein References for BAGE4 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for BAGE4 Gene

Domains for BAGE4 Gene

Protein Domains for BAGE4 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for BAGE4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q86Y28

UniProtKB/Swiss-Prot:

BAGE4_HUMAN :
  • Q86Y28
Family:
  • Belongs to the BAGE family.
genes like me logo Genes that share domains with BAGE4: view

No data available for Gene Families for BAGE4 Gene

Function for BAGE4 Gene

Molecular function for BAGE4 Gene

UniProtKB/Swiss-Prot Function: Unknown. Candidate gene encoding tumor antigens

Phenotypes for BAGE4 Gene

GenomeRNAi human phenotypes for BAGE4:
genes like me logo Genes that share phenotypes with BAGE4: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for BAGE4 Gene

Localization for BAGE4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BAGE4 Gene

Secreted.

Gene Ontology (GO) - Cellular Components for BAGE4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with BAGE4: view

No data available for Subcellular locations from COMPARTMENTS for BAGE4 Gene

Pathways for BAGE4 Gene

SuperPathways for BAGE4 Gene

No Data Available

Interacting Proteins for BAGE4 Gene

Gene Ontology (GO) - Biological Process for BAGE4 Gene

None

No data available for Pathways by source for BAGE4 Gene

Transcripts for BAGE4 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for BAGE4 Gene

No ASD Table

Relevant External Links for BAGE4 Gene

ECgene alternative splicing isoforms for
BAGE4

Expression for BAGE4 Gene

mRNA expression in normal human tissues for BAGE4 Gene

mRNA expression in normal human tissues for BAGE4 Gene

mRNA Expression by UniProt/SwissProt for BAGE4 Gene

Q86Y28-BAGE4_HUMAN
Tissue specificity: Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas
genes like me logo Genes that share expressions with BAGE4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Protein expression for BAGE4 Gene

Orthologs for BAGE4 Gene

No data available for Orthologs and Evolution for BAGE4 Gene

Paralogs for BAGE4 Gene

Selected SIMAP similar genes for BAGE4 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with BAGE4: view

No data available for Paralogs for BAGE4 Gene

Variants for BAGE4 Gene

Structural Variations from Database of Genomic Variants (DGV) for BAGE4 Gene

Variant ID Type Subtype PubMed ID
esv28756 CNV Gain+Loss 19812545
nsv428382 CNV Gain+Loss 18775914
dgv712n67 CNV Gain 20364138
esv32564 CNV Gain+Loss 17666407
esv29976 CNV Gain 17803354
nsv437841 CNV Loss 16327808
dgv1349e1 CNV Complex 17122850
esv720 CNV CNV 17122850
esv1000174 CNV Deletion 20482838
nsv436336 CNV Deletion 17901297
nsv512628 CNV Loss 21212237
esv2661615 CNV Deletion 23128226
esv991443 OTHER Inversion 20482838
nsv828817 CNV Gain 20364138
nsv469643 CNV Loss 16826518
dgv1350e1 CNV Complex 17122850
nsv834041 CNV Gain 17160897
nsv9838 CNV Gain+Loss 18304495
nsv820736 CNV Duplication 20802225
esv1008267 CNV Deletion 20482838
esv9537 CNV Loss 19470904
esv987944 CNV Deletion 20482838
nsv819478 CNV Gain 19587683
esv1008615 CNV Deletion 20482838
nsv828818 CNV Gain 20364138
nsv471421 CNV Duplication 19718026
esv1001067 CNV Insertion 20482838
nsv512629 CNV Loss 21212237
esv7291 CNV Loss 19470904
esv2563009 CNV Deletion 19546169
esv2675165 CNV Deletion 23128226
nsv435743 CNV Deletion 17901297
esv2474693 CNV Deletion 19546169
nsv436329 CNV Deletion 17901297
esv999403 CNV Deletion 20482838
nsv498974 CNV Loss 21111241
nsv3451 CNV Insertion 18451855
dgv73n16 CNV Deletion 17901297
nsv512630 CNV Loss 21212237
esv999554 CNV Insertion 20482838
esv1002199 CNV Deletion 20482838

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Relevant External Links for BAGE4 Gene

Disorders for BAGE4 Gene

No disorders were found for BAGE4 Gene.

No data available for UniProtKB/Swiss-Prot for BAGE4 Gene

Publications for BAGE4 Gene

  1. BAGE genes generated by juxtacentromeric reshuffling in the hominidae lineage are under selective pressure. (PMID: 12676563) Ruault M. … De Sario A. (Genomics 2003) 2 3
  2. BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes. (PMID: 7895173) Boel P. … van der Bruggen P. (Immunity 1995) 3
  3. New BAGE (B melanoma antigen) genes mapping to the juxtacentromeric regions of human chromosomes 13 and 21 have a cancer/testis expression profile. (PMID: 12461691) Ruault M. … De Sario A. (Eur. J. Hum. Genet. 2002) 3

Products for BAGE4 Gene

Sources for BAGE4 Gene

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