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Aliases & Descriptions for BAGE3
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| | | Descriptions |
|---|
| B melanoma antigen family, member 3 2 | | Cancer/testis antigen 2.3 3 | | cancer/testis antigen family 2, member 3 2 |
|
| | Search outside databases for aliases for BAGE3 genePrevious GC identifers: GC00U991012 GC21M010071 GC21M010044 |
Summaries for BAGE3(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: BAGE3_HUMAN, Q86Y29Function: Unknown. Candidate gene encoding tumor antigens |
Genomic Location for BAGE3
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 21p11.2 Ensembl cytogenetic band: 21p11.1 HGNC cytogenetic band: 21p11.2BAGE3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 21 GeneLoc Exon Structure GeneLoc location for GC21M010042:
(about GC identifiers)
Start:
|
10,042,713 bp from pter |
End:
|
10,120,608 bp from pter |
Size:
|
77,896 bases |
Orientation:
|
minus strand |
| Proteins for BAGE3
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: BAGE3_HUMAN, Q86Y29 (See
protein sequence)Recommended Name: B melanoma antigen 3 precursor Size: 109 amino acids; 12112 Da
Subcellular location: Secreted (Potential)
Miscellaneous: The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21REFSEQ proteins: NP_872287.1
ENSEMBL proteins: ENSP00000349289 ENSP00000335528
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
1 Gene Ontology (GO) cellular component term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- | About this table
Antibodies for BAGE3: Assays for BAGE3: | Protein
Domains/ Families for BAGE3(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q86Y29
ProtoNet protein and cluster: Q86Y29 1 Blocks protein family: IPB012530 B melanoma antigen
UniProtKB/Swiss-Prot: BAGE3_HUMAN, Q86Y29Similarity: Belongs to the BAGE family | Gene Function for BAGE3
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_182481
Applied Biosystems Silencer® siRNAs for BAGE3
Sigma-Aldrich siRNA for BAGE3  Sigma-Aldrich shRNA for BAGE3  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_182481                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_182481                                  untagged cDNA clone in CMV expression vector: NM_182481 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_182481
UniProtKB/Swiss-Prot: BAGE3_HUMAN, Q86Y29Function: Unknown. Candidate gene encoding tumor antigens | Pathways & Interactions for BAGE3
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
5/21 Interacting proteins for BAGE3 (ENSP000003355283) via UniProtKB, MINT, and/or STRING (see all 21
)About this table
|
Drugs & Compounds for BAGE3(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for BAGE3
|
Transcripts for BAGE3(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_182481
Sigma-Aldrich siRNA for BAGE3  Sigma-Aldrich shRNA for BAGE3  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_182481 REFSEQ mRNAs for BAGE3 gene: NM_182481.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_182481               OriGene GFP tagged cDNA clone in CMV expression vector: NM_182481                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_182481                                  untagged cDNA clone in CMV expression vector: NM_182481  20 AceView cDNA sequences:NM_182482 AF218570 BG501498 CD359687 BC064647 NM_182481 AF339514 H55516 NM_181704 NM_182484 AF339515 AF339516 BG723950 NM_001187 U19180 BE084888 AV750850 AI138404 BC037276 AU099705
highest scoring ESTs for BAGE3:AU099705 BC037276 BG723950 AV750850 BC101134 BE084888 CD359687 NM_181704 NM_182481 NM_182482
GeneLoc Exon Structure
2 Ensembl transcripts including schematic representations: ENST00000356832
ENST00000335369
|
Expression for BAGE3
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| BAGE3 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for BAGE3
/ 2 / 3 2 probe-sets matching BAGE3 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: -- UniProtKB/Swiss-Prot: BAGE3_HUMAN, Q86Y29Tissue specificity: Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas |
Orthologs for BAGE3
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for BAGE3 | Paralogs for BAGE3(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| -- |
SNPs/Variants for BAGE3(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
| -- |
Disorders & Mutations for BAGE3
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News for BAGE3(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for BAGE3 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 6 PubMed articles for BAGE3 gene: |
Search for BAGE3
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing BAGE3
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing BAGE3
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BAGE3(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for BAGE3(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for BAGE3:

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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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