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Aliases for BAGE2 Gene

Aliases for BAGE2 Gene

  • BAGE Family Member 2 2 3 5
  • Cancer/Testis Antigen Family 2, Member 2 2 3
  • Cancer/Testis Antigen 2.2 3 4
  • CT2.2 3 4
  • B Melanoma Antigen Family, Member 2 2
  • B Melanoma Antigen Family Member 2 3
  • B Melanoma Antigen 2 3

External Ids for BAGE2 Gene

Previous GeneCards Identifiers for BAGE2 Gene

  • GC21U990099
  • GC21M010043
  • GC21M010072
  • GC21M010996

Summaries for BAGE2 Gene

GeneCards Summary for BAGE2 Gene

BAGE2 (BAGE Family Member 2) is a Protein Coding gene. Diseases associated with BAGE2 include Melanoma.

UniProtKB/Swiss-Prot for BAGE2 Gene

  • Unknown. Candidate gene encoding tumor antigens.

Additional gene information for BAGE2 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BAGE2 Gene

Genomics for BAGE2 Gene

Regulatory Elements for BAGE2 Gene

Enhancers for BAGE2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH21H010416 0.6 FANTOM5 2 +3.0 3039 0.4 ESRRA NFRKB CEBPG HDAC8 RFX5 ZNF507 SREBF1 ZBTB33 BAGE2 LOC105378260
GH21H010327 0.5 FANTOM5 1.4 -86.0 -85967 0.4 ZFX ZNF507 BAGE2 EIF3FP1 LOC100420925
GH21H010429 0.4 FANTOM5 0.4 +16.5 16521 0.3 ZNF354B BAGE2 LOC105378260
GH21H010422 0.3 FANTOM5 0.4 +8.7 8660 0 BAGE2 LOC105378260
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around BAGE2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for BAGE2 Gene

Genomic Locations for BAGE2 Gene
102,955 bases
Plus strand

Genomic View for BAGE2 Gene

Genes around BAGE2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BAGE2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BAGE2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BAGE2 Gene

Proteins for BAGE2 Gene

  • Protein details for BAGE2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    B melanoma antigen 2
    Protein Accession:
    Secondary Accessions:
    • A8K925
    • Q08ER0

    Protein attributes for BAGE2 Gene

    109 amino acids
    Molecular mass:
    12114 Da
    Quaternary structure:
    No Data Available
    • The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the KMT2C/MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21.

neXtProt entry for BAGE2 Gene

Post-translational modifications for BAGE2 Gene

No Post-translational modifications

Other Protein References for BAGE2 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for BAGE2 Gene

Domains & Families for BAGE2 Gene

Protein Domains for BAGE2 Gene


Suggested Antigen Peptide Sequences for BAGE2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the BAGE family.
  • Belongs to the BAGE family.
genes like me logo Genes that share domains with BAGE2: view

No data available for Gene Families for BAGE2 Gene

Function for BAGE2 Gene

Molecular function for BAGE2 Gene

UniProtKB/Swiss-Prot Function:
Unknown. Candidate gene encoding tumor antigens.
genes like me logo Genes that share phenotypes with BAGE2: view

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No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BAGE2 Gene

Localization for BAGE2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for BAGE2 Gene


Gene Ontology (GO) - Cellular Components for BAGE2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with BAGE2: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for BAGE2 Gene

Pathways & Interactions for BAGE2 Gene

SuperPathways for BAGE2 Gene

No Data Available

Interacting Proteins for BAGE2 Gene

Gene Ontology (GO) - Biological Process for BAGE2 Gene


No data available for Pathways by source and SIGNOR curated interactions for BAGE2 Gene

Drugs & Compounds for BAGE2 Gene

No Compound Related Data Available

Transcripts for BAGE2 Gene

mRNA/cDNA for BAGE2 Gene

(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

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Alternative Splicing Database (ASD) splice patterns (SP) for BAGE2 Gene

No ASD Table

Relevant External Links for BAGE2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for BAGE2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for BAGE2 Gene

mRNA differential expression in normal tissues according to GTEx for BAGE2 Gene

This gene is overexpressed in Testis (x32.5) and Stomach (x6.7).

NURSA nuclear receptor signaling pathways regulating expression of BAGE2 Gene:


mRNA Expression by UniProt/SwissProt for BAGE2 Gene:

Tissue specificity: Not expressed in normal tissues except in testis. Expressed in 22% of melanomas, in bladder and lung carcinomas.
genes like me logo Genes that share expression patterns with BAGE2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BAGE2 Gene

Orthologs for BAGE2 Gene

Evolution for BAGE2 Gene

Gene Tree for BAGE2 (if available)
Gene Tree for BAGE2 (if available)

No data available for Orthologs for BAGE2 Gene

Paralogs for BAGE2 Gene

(4) SIMAP similar genes for BAGE2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with BAGE2: view

No data available for Paralogs for BAGE2 Gene

Variants for BAGE2 Gene

Sequence variations from dbSNP and Humsavar for BAGE2 Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type
rs1000233538 -- 10,413,499(-) ATGCA(C/T)ATGGG upstream-variant-2KB
rs1000978232 -- 10,445,295(-) TAGTA(A/G)CCAAC intron-variant
rs1001164393 -- 10,462,558(-) TATTC(C/T)TAATG intron-variant, upstream-variant-2KB
rs1001965476 -- 10,422,510(-) CCTCA(A/G)GTTAT intron-variant
rs1003344228 -- 10,440,748(-) CAGAG(A/G)CCTAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for BAGE2 Gene

Variant ID Type Subtype PubMed ID
nsv9838 CNV gain+loss 18304495
nsv979515 CNV duplication 23825009
nsv965987 CNV duplication 23825009
nsv965965 CNV duplication 23825009
nsv965963 CNV duplication 23825009
nsv964473 CNV duplication 23825009
nsv964472 CNV duplication 23825009
nsv956736 CNV deletion 24416366
nsv954302 CNV deletion 24416366
nsv953332 CNV duplication 24416366
nsv953331 CNV duplication 24416366
nsv834041 CNV gain 17160897
nsv828818 CNV gain 20364138
nsv828817 CNV gain 20364138
nsv820736 CNV duplication 20802225
nsv819478 CNV gain 19587683
nsv586980 CNV loss 21841781
nsv586979 CNV loss 21841781
nsv586978 CNV gain 21841781
nsv512630 CNV loss 21212237
nsv512629 CNV loss 21212237
nsv512628 CNV loss 21212237
nsv498974 CNV loss 21111241
nsv471421 CNV gain 19718026
nsv469643 CNV loss 16826518
nsv437841 CNV loss 16327808
nsv436336 CNV deletion 17901297
nsv436329 CNV deletion 17901297
nsv435743 CNV deletion 17901297
nsv428382 CNV gain+loss 18775914
nsv3451 CNV insertion 18451855
nsv1151660 CNV duplication 26484159
nsv1150038 CNV deletion 26484159
nsv1143010 CNV tandem duplication 24896259
nsv1138997 CNV deletion 24896259
nsv1138996 CNV deletion 24896259
nsv1138995 CNV deletion 24896259
nsv1138994 CNV deletion 24896259
nsv1136593 CNV deletion 24896259
nsv1136592 CNV deletion 24896259
nsv1136590 CNV deletion 24896259
nsv1136589 CNV deletion 24896259
nsv1123525 CNV deletion 24896259
nsv1123524 CNV deletion 24896259
nsv1123523 CNV deletion 24896259
nsv1116897 CNV deletion 24896259
nsv1114259 CNV deletion 24896259
nsv1109407 CNV deletion 24896259
nsv1078497 CNV duplication 25765185
nsv1073111 CNV deletion 25765185
nsv1073110 CNV deletion 25765185
nsv1073109 CNV deletion 25765185
nsv1073108 CNV deletion 25765185
nsv1072757 CNV deletion 25765185
nsv1072156 CNV deletion 25765185
nsv1072155 CNV deletion 25765185
nsv1071741 CNV deletion 25765185
nsv1071740 CNV deletion 25765185
nsv1071739 CNV deletion 25765185
nsv1071738 CNV deletion 25765185
nsv1071737 CNV deletion 25765185
nsv1071408 CNV deletion 25765185
nsv1071405 CNV deletion 25765185
nsv1064913 CNV gain 25217958
nsv1064391 CNV loss 25217958
nsv1060052 CNV loss 25217958
nsv1059477 CNV gain 25217958
nsv1059291 CNV loss 25217958
nsv1057510 CNV loss 25217958
esv999554 CNV insertion 20482838
esv999403 CNV deletion 20482838
esv991443 OTHER inversion 20482838
esv987944 CNV deletion 20482838
esv9537 CNV loss 19470904
esv7291 CNV loss 19470904
esv3646371 CNV loss 21293372
esv3557434 CNV deletion 23714750
esv3557431 CNV deletion 23714750
esv3412511 CNV insertion 20981092
esv32564 CNV gain+loss 17666407
esv3057124 CNV deletion 24192839
esv29976 CNV gain 17803354
esv28756 CNV gain+loss 19812545
esv2763681 CNV gain+loss 21179565
esv2760704 CNV gain 21179565
esv2758808 CNV gain+loss 17122850
esv2675165 CNV deletion 23128226
esv2661615 CNV deletion 23128226
esv2563009 CNV deletion 19546169
esv2474693 CNV deletion 19546169
esv1008615 CNV deletion 20482838
esv1008267 CNV deletion 20482838
esv1002199 CNV deletion 20482838
esv1001067 CNV insertion 20482838
esv1000174 CNV deletion 20482838
dgv7743n54 CNV gain 21841781
dgv7729n54 CNV gain 21841781
dgv7728n54 CNV gain 21841781
dgv73n16 CNV deletion 17901297
dgv712n67 CNV gain 20364138
dgv4373n100 CNV gain+loss 25217958
dgv4372n100 CNV loss 25217958
dgv4371n100 CNV gain 25217958
dgv4370n100 CNV loss 25217958
dgv4369n100 CNV gain 25217958
dgv4368n100 CNV gain+loss 25217958
dgv4367n100 CNV gain 25217958
dgv4363n100 CNV loss 25217958
dgv4358n100 CNV gain 25217958
dgv4356n100 CNV loss 25217958
dgv4355n100 CNV gain 25217958
dgv4354n100 CNV gain+loss 25217958
dgv4353n100 CNV loss 25217958
dgv2468e59 CNV duplication 20981092
dgv2354n106 CNV deletion 24896259
dgv2353n106 CNV deletion 24896259
dgv2352n106 CNV deletion 24896259
dgv2351n106 CNV deletion 24896259
dgv2350n106 CNV deletion 24896259
dgv2349n106 CNV duplication 24896259

Relevant External Links for BAGE2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for BAGE2 Gene

Disorders for BAGE2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for BAGE2 Gene - From: GeneCards

Disorder Aliases PubMed IDs
  • malignant melanoma
- elite association - COSMIC cancer census association via MalaCards
Search BAGE2 in MalaCards View complete list of genes associated with diseases

Relevant External Links for BAGE2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with BAGE2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for BAGE2 Gene

Publications for BAGE2 Gene

  1. New BAGE (B melanoma antigen) genes mapping to the juxtacentromeric regions of human chromosomes 13 and 21 have a cancer/testis expression profile. (PMID: 12461691) Ruault M … De Sario A (European journal of human genetics : EJHG 2002) 2 3 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. Juxtacentromeric region of human chromosome 21: a boundary between centromeric heterochromatin and euchromatic chromosome arms. (PMID: 12909339) Brun ME … De Sario A (Gene 2003) 3 22 60
  4. BAGE genes generated by juxtacentromeric reshuffling in the Hominidae lineage are under selective pressure. (PMID: 12676563) Ruault M … De Sario A (Genomics 2003) 3 4 60
  5. A possible mechanism behind autoimmune disorders discovered by genome-wide linkage and association analysis in celiac disease. (PMID: 23936387) Östensson M … Torinsson-Naluai Å (PloS one 2013) 3 60

Products for BAGE2 Gene

Sources for BAGE2 Gene

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