Aliases for BAGE Gene
Aliases for BAGE Gene
Previous GeneCards Identifiers for BAGE Gene
- GC21M007820
- GC21M010080
- GC21M010047
- GC07M151408
- GC21M010079
- GC21M011000
Summaries for BAGE Gene
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This gene encodes a tumor antigen recognized by autologous cytolytic lymphocytes (CTL). [provided by RefSeq, Jul 2008]
GeneCards Summary for BAGE Gene
BAGE (B Melanoma Antigen) is a Protein Coding gene. Diseases associated with BAGE include Melanoma.
UniProtKB/Swiss-Prot for BAGE Gene
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Unknown. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BAGE Gene
Proteins for BAGE Gene
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Protein details for BAGE Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q13072-BAGE1_HUMAN
- Recommended name:
- B melanoma antigen 1
- Protein Accession:
- Q13072
- A4IF47
Protein attributes for BAGE Gene
- Size:
- 43 amino acids
- Molecular mass:
- 4810 Da
- Quaternary structure:
- No Data Available
- Miscellaneous:
-
- The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the KMT2C/MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21.
Alternative splice isoforms for BAGE Gene
- UniProtKB/Swiss-Prot:
Protein Expression for BAGE Gene
Post-translational modifications for BAGE Gene
No Post-translational modifications
Other Protein References for BAGE Gene
- REFSEQ proteins:
Antibody Products
- Search GeneTex for Antibodies for BAGE
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for BAGE
- Origene Custom Protein Services for BAGE
- Search GeneTex for Proteins for BAGE
Assay Products
No data available for DME Specific Peptides for BAGE Gene
Domains & Families for BAGE Gene
Protein Domains for BAGE Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for BAGE Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q13072- Family:
-
- Belongs to the BAGE family.
No data available for Gene Families for BAGE Gene
Function for BAGE Gene
Molecular function for BAGE Gene
- UniProtKB/Swiss-Prot Function:
- Unknown. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Phenotypes for BAGE Gene
- GenomeRNAi human phenotypes for BAGE:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for BAGE
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ViGene Biosciences lentiviral particle packaged cDNA for BAGE gene
- Search ViGene Biosciences for BAGE
miRNA Products
- Search ViGene Biosciences for BAGE
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for BAGE
- Browse OriGene Inhibitory RNA Products For BAGE
- Search ViGene Biosciences for BAGE
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for BAGE
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BAGE
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
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ViGene Biosciences adenoviral particle packaged cDNA for BAGE gene
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ViGene Biosciences lentiviral particle packaged cDNA for BAGE gene
- Search ViGene Biosciences for BAGE
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BAGE Gene
Localization for BAGE Gene
Subcellular locations from UniProtKB/Swiss-Prot for BAGE Gene
- Secreted.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
No data available for Subcellular locations from COMPARTMENTS for BAGE Gene
Transcripts for BAGE Gene
mRNA/cDNA for BAGE Gene
miRNA Products
- Search ViGene Biosciences for BAGE
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for BAGE
- Browse OriGene Inhibitory RNA Products For BAGE
- Search ViGene Biosciences for BAGE
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for BAGE
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BAGE
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Relevant External Links for BAGE Gene
- ECgene alternative splicing isoforms for
- BAGE
Expression for BAGE Gene
This gene is overexpressed in Heart (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for BAGE Gene
NURSA nuclear receptor signaling pathways regulating expression of BAGE Gene:
BAGESOURCE GeneReport for Unigene cluster for BAGE Gene:
Hs.545789mRNA Expression by UniProt/SwissProt for BAGE Gene:
Q13072-BAGE1_HUMAN
Tissue specificity:
Not expressed in normal tissues, except in testis. Expressed with significant proportion in melanomas, but also in tumors of various histological origins, such as bladder carcinomas, head and neck squamous cell carcinomas, lung and breast carcinomas. Not expressed in renal, colorectal and prostatic carcinomas, leukemias and lymphomas. More frequently expressed in metastatic melanomas than in primary melanomas.
Primer Products
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OriGene qPCR primer pairs and template standards for BAGE
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for BAGE Gene
Orthologs for BAGE Gene
No data available for Orthologs and Evolution for BAGE Gene
Paralogs for BAGE Gene
(4) SIMAP similar genes for BAGE Gene using alignment to 2 proteins:
No data available for Paralogs for BAGE Gene
Variants for BAGE Gene
Relevant External Links for BAGE Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- BAGE
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for BAGE Gene
Disorders for BAGE Gene
Search BAGE in MalaCards
View complete list of genes associated with diseases
Relevant External Links for BAGE
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- BAGE
No data available for UniProtKB/Swiss-Prot and Genatlas for BAGE Gene
Publications for BAGE Gene
- BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes. (PMID: 7895173) Boel P. … van der Bruggen P. (Immunity 1995) 2 3 4 22 64
- New BAGE (B melanoma antigen) genes mapping to the juxtacentromeric regions of human chromosomes 13 and 21 have a cancer/testis expression profile. (PMID: 12461691) Ruault M. … De Sario A. (Eur. J. Hum. Genet. 2002) 3 4 22 64
- Expression of tumor-specific antigen MAGE, GAGE and BAGE in ovarian cancer tissues and cell lines. (PMID: 20423514) Zhang S. … Yu Y. (BMC Cancer 2010) 3 22 64
- BAGE hypomethylation, a new epigenetic biomarker for colon cancer detection. (PMID: 18541613) Grunau C. … De Sario A. (Cancer Epidemiol. Biomarkers Prev. 2008) 3 22 64
- Frequent DNA hypomethylation of human juxtacentromeric BAGE loci in cancer. (PMID: 15704127) Grunau C. … De Sario A. (Genes Chromosomes Cancer 2005) 3 22 64
Products for BAGE Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for BAGE
- Origene Custom Protein Services for BAGE
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for BAGE
- Browse OriGene Inhibitory RNA Products For BAGE
- OriGene qPCR primer pairs and template standards for BAGE
- OriGene CRISPR knockouts for BAGE
- OriGene ORF clones in human for BAGE
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For BAGE
- GenScript: Next-day shipping cDNA ORF clone for BAGE in any vector
- GenScript Custom Purified and Recombinant Proteins Services for BAGE
- GenScript Custom Assay Services for BAGE
- GenScript Custom overexpressing Cell Line Services for BAGE
- Browse GenScript CRISPR for BAGE
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for BAGE
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ViGene Biosciences adenoviral particle packaged cDNA for BAGE gene
- ViGene Biosciences lentiviral particle packaged cDNA for BAGE gene
- Search ViGene Biosciences for BAGE
- Cyagen custom Knockout/knockin (KOKI) mouse models for BAGE
- VectorBuilder custom plasmid, inducible vectors for BAGE
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BAGE
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for BAGE Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
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- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
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- (128) Genetics Home Reference
- (129) MeSH
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- (133) NCBI Bookshelf
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- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer