BAG6 Gene
protein-coding GIFtS: 53
GCID: GC06M031648
|
|
BCL2-associated athanogene 6(Previous name: HLA-B associated transcript 3 )
(Previous symbol: BAT3)
| |
Aliases
for BAG6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| BCL2-Associated Athanogene 61 2 3 | | BAG-62 3 | | BAT31 2 3 5 | | BAG Family Molecular Chaperone Regulator 62 3 | | G31 2 3 | | HLA-B-Associated Transcript 32 3 | | D6S52E1 2 5 | | HLA-B Associated Transcript-32 | | HLA-B Associated Transcript 31 2 | | Large Proline-Rich Protein BAG62 | | Protein G32 3 | | Large Proline-Rich Protein BAT32 | | Protein Scythe2 3 | | Scythe1 |
Export aliases for BAG6 gene to outside databasesPrevious GC identifers: GC06M031392 GC06M031632 GC06M031636 GC06M031639 GC06M031643 |
Summaries
for BAG6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for BAG6:
This gene was first characterized as part of a cluster of genes located within the human major histocompatibilitycomplex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in thecontrol of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for theacetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been foundfor this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: BAG6_HUMAN, P46379Function: Chaperone that plays a key role in various processes such as apoptosis, insertion of tail-anchored (TA)membrane proteins to the endoplasmic reticulum membrane and regulation of chromatin. Acts in part by regulatingstability of proteins and their degradation by the proteasome. Participates in endoplasmic reticulum stress-inducedapoptosis via its interaction with AIFM1/AIF by regulating AIFM1/AIF stability and preventing its degradation. Alsorequired during spermatogenesis for synaptonemal complex assembly via its interaction with HSPA2, by inhibitingpolyubiquitination and subsequent proteasomal degradation of HSPA2. Required for selective ubiquitin-mediateddegradation of defective nascent chain polypeptides by the proteasome. In this context, may play a role inimmuno-proteasomes to generate antigenic peptides via targeted degradation, thereby playing a role in antigenpresentation in immune response. Key component of the BAG6/BAT3 complex, a cytosolic multiprotein complex involved inthe post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TAmembrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region.BAG6/BAT3 acts by facilitating TA membrane proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizingmembrane proteins, interacts with the transmembrane region of newly released TA proteins and transfers them toASNA1/TRC40 for targeting to the endoplasmic reticulum membraneFunction: Involved in DNA damage-induced apoptosis: following DNA damage, accumulates in the nucleus and forms acomplex with p300/EP300, enhancing p300/EP300-mediated p53/TP53 acetylation leading to increase p53/TP53transcriptional activity. When nuclear, may also act as a component of some chromatin regulator complex that regulateshistone 3 'Lys-4' dimethylation (H3K4me2)Function: Can be released from tumor and dendritic cells in membrane vesicles or exosomes, and engage NCR3 therebypromoting natural killer cell (NK) activation and cytotoxicity
Gene Wiki entry for BAG6 (HLA-B associated transcript 3)
|
Genomic Views
for BAG6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15 NT_113891.2 NT_167245.1 NT_167246.1 NT_167247.1 NT_167248.1
- NT_167249.1
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for BAG6
Other transcription factors
Search SABiosciences Chromatin IP Primers for BAG6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BAG6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.3 Ensembl cytogenetic band: 6p21.33 HGNC cytogenetic band: 6p21.3BAG6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M031648: view genomic region
(about GC identifiers)
Start:
|
31,606,805 bp from pter |
End:
|
31,620,482 bp from pter |
Size:
|
13,678 bases |
Orientation:
|
minus strand |
6 alternative locations:
| Chr6-,ALT_REF_LOCI_4 31,569,347-31,583,025 | Chr6-,ALT_REF_LOCI_2 31,594,212-31,647,080 | Chr6-,ALT_REF_LOCI_5 31,597,915-31,611,580 | | Chr6-,ALT_REF_LOCI_6 31,597,040-31,646,299 | Chr6-,ALT_REF_LOCI_3 31,588,979-31,613,697 | Chr6-,ALT_REF_LOCI_7 31,527,067-31,540,741 | |
|
Proteins
for BAG6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BAG6_HUMAN, P46379 (See
protein sequence)Recommended Name: Large proline-rich protein BAG6 Size: 1132 amino acids; 119409 Da
Subunit: Component of the BAT3 complex, at least composed of BAG6/BAT3, UBL4A and GET3/TRC35. Interacts with AIFM1,CTCFL, HSPA2 and p300/EP300. Interacts with ricin A chain. Interacts with L.pneumophila proteins Lpg2160 and LegU1.Interacts with NCR3
Subcellular location: Cytoplasm, cytosol. Nucleus. Note=The C-terminal fragment generated by caspase-3 is cytoplasmic.Also found in extracellular vesicular exosomes in some tumor cells
Sequence caution: Sequence=AAD18085.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=BAB63390.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=CAI18318.2;Type=Erroneous gene model prediction;
3 PDB 3D structures from  and Proteopedia  for BAG6:1WX9 (3D)
4DWF (3D)
4EEW (3D)
Secondary accessions: A2ADJ7 A3KQ42 A3KQ44 A6NGY6 A6PWF7 B0UX84 B4DZ12 B4E3V4 E7EMZ4 F8VXY4 O95874Q5HYL9 Q5SQ35 Q5SQ36 Q5SQ37 Q5SQ41 Q5SRP8 Q5SRP9 Q5STC1 Q5STX1 Q5STX3 Q96SA6 Q9BCN4Alternative splicing: 5 isoforms: P46379-1 P46379-2 P46379-3 P46379-4 P46379-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for BAG6: NX_P46379
Post-translational modifications:
Cleavage by caspase-3 releases a C-terminal peptide that plays a role in ricin-induced apoptosis1
In case of infection by L.pneumophila, ubiquitinated by the SCF(LegU1) complex1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P46379
BAG6 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (6 alternative transcripts):
NP_001092004.1 NP_001186626.1 NP_001186627.1 NP_004630.3 NP_542433.1 NP_542434.1
ENSEMBL proteins: ENSP00000413225 ENSP00000416633 ENSP00000365143 ENSP00000365131 ENSP00000211379 ENSP00000397978 ENSP00000410280 ENSP00000401544 ENSP00000406434 ENSP00000411083 ENSP00000394856 ENSP00000404971 ENSP00000401031 ENSP00000413561 ENSP00000391613 ENSP00000388244 ENSP00000411043 ENSP00000391783 ENSP00000403629 ENSP00000406302 ENSP00000406436 ENSP00000396503 ENSP00000384494 ENSP00000402856 ENSP00000354875
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
BAG6 for ontologies About GeneDecksing
BAG6 Antibody Products:
Assay Products for BAG6: |
Protein
Domains /
Families
for BAG6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BAG6 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P46379ProtoNet protein and cluster: P46379 1 Blocks protein family: IPB000626 Ubiquitin domain
UniProtKB/Swiss-Prot: BAG6_HUMAN, P46379Similarity: Contains 1 ubiquitin-like domain |
Function
for BAG6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: BAG6_HUMAN, P46379Function: Chaperone that plays a key role in various processes such as apoptosis, insertion of tail-anchored (TA)membrane proteins to the endoplasmic reticulum membrane and regulation of chromatin. Acts in part by regulatingstability of proteins and their degradation by the proteasome. Participates in endoplasmic reticulum stress-inducedapoptosis via its interaction with AIFM1/AIF by regulating AIFM1/AIF stability and preventing its degradation. Alsorequired during spermatogenesis for synaptonemal complex assembly via its interaction with HSPA2, by inhibitingpolyubiquitination and subsequent proteasomal degradation of HSPA2. Required for selective ubiquitin-mediateddegradation of defective nascent chain polypeptides by the proteasome. In this context, may play a role inimmuno-proteasomes to generate antigenic peptides via targeted degradation, thereby playing a role in antigenpresentation in immune response. Key component of the BAG6/BAT3 complex, a cytosolic multiprotein complex involved inthe post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TAmembrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region.BAG6/BAT3 acts by facilitating TA membrane proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizingmembrane proteins, interacts with the transmembrane region of newly released TA proteins and transfers them toASNA1/TRC40 for targeting to the endoplasmic reticulum membraneFunction: Involved in DNA damage-induced apoptosis: following DNA damage, accumulates in the nucleus and forms acomplex with p300/EP300, enhancing p300/EP300-mediated p53/TP53 acetylation leading to increase p53/TP53transcriptional activity. When nuclear, may also act as a component of some chromatin regulator complex that regulateshistone 3 'Lys-4' dimethylation (H3K4me2)Function: Can be released from tumor and dendritic cells in membrane vesicles or exosomes, and engage NCR3 therebypromoting natural killer cell (NK) activation and cytotoxicity
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BAG6 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BAG6 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 6): BAG6 (NM_004639) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BAG6 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BAG6 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BAG6 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
BAG6 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for BAG6:
Animal Models:
Mouse knock-out Bag6tm1Pmc for BAG6
6 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Bag6):
BAG6 for phenotypes About GeneDecksing
|
Pathways & Interactions
for BAG6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | TGF-beta/Smad Signaling | | | 2 | Protein Stability | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Cell Signaling Technology (CST) Pathways for BAG6
BAG6 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BAG6
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/172 Interacting proteins for BAG6 (P463791, 2, 3 ENSP000003651314) via UniProtKB, MINT, STRING, and/or I2D (see all 172)About this table
Gene Ontology (GO): 5/18 biological process terms (GO ID links to tree view) (see all 18): About this table
BAG6 for ontologies About GeneDecksing
|
Drugs & Compounds
for BAG6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
BAG6 for compounds About GeneDecksing
 Browse Tocris compounds for BAG6
1 PharmGKB related drug/compound annotation for BAG6 geneAbout this table
Search CenterWatch for drugs/clinical trials and news about BAG6
|
Transcripts
for BAG6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BAG6 gene (6 alternative transcripts): NM_001098534.1 NM_001199697.1 NM_001199698.1 NM_004639.3 NM_080702.2 NM_080703.2 Unigene Cluster for BAG6: BCL2-associated athanogene 6 Hs.440900 [show with all ESTs]Unigene Representative Sequence: NM_00463918/34 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 34): ENST00000464869 ENST00000464126 ENST00000422948 ENST00000441793 ENST00000375976(uc003nvf.4)
ENST00000375964 ENST00000211379(uc003nvi.4 uc003nvh.4 uc003nvg.4 uc011dnw.2 uc011dnx.2)
ENST00000462875 ENST00000470875 ENST00000437771 ENST00000465348 ENST00000438149
ENST00000436214 ENST00000469182 ENST00000453833 ENST00000435080 ENST00000462682
ENST00000434444
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BAG6 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BAG6 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 6): BAG6 (NM_004639) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BAG6 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BAG6 |
Additional cDNA sequence: AK302695.1 AK304879.1 BC003133.1 BC131567.1 BX647244.1 M33519.1 24/44 DOTS entries (see all 44): DT.454198 DT.95301397 DT.97856192 DT.100650022 DT.100852263 DT.100852256 DT.92458340 DT.92458327 DT.95301422 DT.100852276 DT.100805964 DT.95301426 DT.92458335 DT.121312722 DT.100852272 DT.100852278 DT.92458341 DT.100852268 DT.100852271 DT.95301373 DT.95348059 DT.100807709 DT.85105594 DT.95301393 24/384 AceView cDNA sequences (see all 384): BM927106 BF594693 BM830544 BG252296 BF194760 BI523628 BU539436 BE271564 BI913608 BG109777 BU146637 CF125935 BM927688 AI623193 BQ929445 BM991023 AL044929 BG818745 AW276474 BQ923162 BU521395 AA715034 BI836477 BE262419
GeneLoc Exon Structure
|
Expression
for BAG6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BAG6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See BAG6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BAG6
SOURCE GeneReport for Unigene cluster: Hs.440900
SABiosciences Custom PCR Arrays for BAG6
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BAG6
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BAG6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BAG6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BAG6 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BAG6 |
Orthologs
for BAG6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for BAG6 gene from 7/19 species (see all 19) About this table
ENSEMBL Gene Tree for BAG6 (if available)
TreeFam Gene Tree for BAG6 (if available) |
Paralogs
for BAG6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for BAG6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BAG6 (31606805 - 31620482 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for BAG6: --
Human Gene Mutation Database (HGMD): BAG6
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BAG6 |
|
Disorders
/ Diseases
for BAG6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BAG6 for disorders About GeneDecksing
OMIM gene information: 142590
OMIM disorders: --
15  diseases for BAG6: About MalaCardscoronary artery aneurysm systemic lupus erythematosus lupus erythematosus acute lymphoblastic leukemia
lymphoblastic leukemia lung cancer susceptibility rheumatoid arthritis lung cancer
arthritis leukemia osteosarcoma ataxia
esophagitis adenocarcinoma sepsis
Export disorders for BAG6 gene to outside databases
|
Publications
for BAG6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BAG6 gene, integrated from 9 sources (see all 98):
(articles sorted by number of sources associating them with BAG6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain. (PubMed id 2156268)1, 2, 3, 9 Banerji J.... Spies T. (1990)
- Human leukocyte antigen-B-associated transcript 3 is released from tumor cells and engages the NKp30 receptor on natural killer cells. (PubMed id 18055229)1, 2, 9 Pogge von Strandmann E....Engert A. (2007)
- A ribosome-associating factor chaperones tail-anchore d membrane proteins. (PubMed id 20676083)1, 2 Mariappan M....Hegde R.S. (2010)
- Bat3 promotes the membrane integration of tail-anchor ed proteins. (PubMed id 20516149)1, 2 Leznicki P....High S. (2010)
- BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression. (PubMed id 18765639)1, 2 Nguyen P.... Gius D. (2008)
- Dendritic cells release HLA-B-associated transcript-3 positive exosomes to regulate natural killer function. (PubMed id 18852879)1, 2 Simhadri V.R....Pogge von Strandmann E. (2008)
- HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53. (PubMed id 17403783)1, 2 Sasaki T....Okada H. (2007)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Ricin triggers apoptotic morphological changes through caspase-3 cleavage of BAT3. (PubMed id 14960581)1, 2 Wu Y.-H.... Lin J.-Y. (2004)
|
External Searches for BAG6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BAG6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BAG6 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BAG6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for BAG6 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for BAG6 gene:
Search GeneIP for patents involving BAG6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BAG6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for BAG6 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BAG6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BAG6 | | | OriGene Protein Over-expression Lysate for BAG6 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for BAG6 | | OriGene 3'-UTR Clone for BAG6 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BAG6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BAG6 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for BAG6 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for BAG6 | | OriGene Custom Protein Services for BAG6 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BAG6 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BAG6 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BAG6 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BAG6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BAG6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BAG6 |
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| | Antibodies & Assays for BAG6 (BAT3) |
| | | | Search Tocris compounds for BAG6 |
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 | | | BAG6 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BAG6 |
|  |  |  | | | | ThermoFisher Antibodies for BAG6 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BAG6 |
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