Aliases for BAG4 Gene
Aliases for BAG4 Gene
External Ids for BAG4 Gene
- HGNC: 940
- Entrez Gene: 9530
- Ensembl: ENSG00000156735
- OMIM: 603884
- UniProtKB: O95429
Previous GeneCards Identifiers for BAG4 Gene
- GC08P037574
- GC08P038162
- GC08P037775
- GC08P038051
- GC08P038153
- GC08P036568
Summaries for BAG4 Gene
-
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
GeneCards Summary for BAG4 Gene
BAG4 (BCL2 Associated Athanogene 4) is a Protein Coding gene. Among its related pathways are TNFR1 Pathway and FGFR1 mutant receptor activation. GO annotations related to this gene include poly(A) RNA binding and signal transducer activity, downstream of receptor. An important paralog of this gene is BAG3.
UniProtKB/Swiss-Prot for BAG4 Gene
-
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling. Negative regulator of PARK2 translocation to damaged mitochondria.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BAG4 Gene
Genomics for BAG4 Gene
Regulatory Elements for BAG4 Gene
Enhancers for BAG4 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around BAG4 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the BAG4 gene promoter:
Regulatory Element Products
Genomic Location for BAG4 Gene
- Chromosome:
- 8
- Start:
- 38,176,533 bp from pter
- End:
- 38,213,301 bp from pter
- Size:
- 36,769 bases
- Orientation:
- Plus strand
Genomic View for BAG4 Gene
Genes around BAG4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8p11.23 by Ensembl
- 8p11.23 by Entrez Gene
- 8p11.23 by HGNC
BAG4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for BAG4 Gene
Proteins for BAG4 Gene
-
Protein details for BAG4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95429-BAG4_HUMAN
- Recommended name:
- BAG family molecular chaperone regulator 4
- Protein Accession:
- O95429
- B4E217
- O95818
Protein attributes for BAG4 Gene
- Size:
- 457 amino acids
- Molecular mass:
- 49594 Da
- Quaternary structure:
-
- Binds to the ATPase domain of HSP/HSC70 chaperones. Binds to the death domain of TNFRSF1A in the absence of TNF and thereby prevents binding of adapter molecules such as TRADD or TRAF2. Binds to the death domain of TNFRSF12. Interacts with PARK2.
Protein Expression for BAG4 Gene
Post-translational modifications for BAG4 Gene
Other Protein References for BAG4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for BAG4
- R&D Systems Antibodies for BAG4 (SODD/BAG4)
-
Custom Antibody ServicesOriGene Antibodies for BAG4
- Novus Biologicals Antibodies for BAG4
- Invitrogen Antibodies for BAG4
- antibodies-online Antibodies for BAG4: See all 116
- GeneTex BAG4 antibody for BAG4
-
Custom Antibody ServicesProSci Antibodies for BAG4
-
Santa Cruz Biotechnology (SCBT) Antibodies for BAG4
Protein Products
-
OriGene Purified Proteins for BAG4
- Search Origene for MassSpec and Protein Over-expression Lysates for BAG4
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- antibodies-online Proteins for BAG4: See all 10
- Search antibodies-online for peptides
- Search GeneTex for Proteins for BAG4
Assay Products
- antibodies-online Kits for BAG4: See all 3
No data available for DME Specific Peptides for BAG4 Gene
Domains & Families for BAG4 Gene
Gene Families for BAG4 Gene
Protein Domains for BAG4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for BAG4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for BAG4 Gene
Function for BAG4 Gene
Molecular function for BAG4 Gene
- GENATLAS Biochemistry:
- BCL2-associated athanogene 4 (antiapoptotic). Negative regulator of Hsp70 chaperone activity
- UniProtKB/Swiss-Prot Function:
- Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling. Negative regulator of PARK2 translocation to damaged mitochondria.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000774 | adenyl-nucleotide exchange factor activity | TAS | -- |
| GO:0003723 | RNA binding | IDA | 22681889 |
| GO:0005057 | signal transducer activity, downstream of receptor | TAS | 9915703 |
| GO:0005515 | protein binding | IPI | 25036637 |
| GO:0031625 | ubiquitin protein ligase binding | IPI | 24270810 |
Phenotypes for BAG4 Gene
- MGI mutant phenotypes for BAG4:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for BAG4:
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for BAG4 gene
-
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CRISPR Products
-
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-
Santa Cruz Biotechnology (SCBT) CRISPR for BAG4
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miRNA for BAG4 Gene
- miRTarBase miRNAs that target BAG4
-
- hsa-mir-96-5p (MIRT027895)
- hsa-mir-183-5p (MIRT047049)
- hsa-mir-26a-5p (MIRT053251)
- hsa-mir-452-5p (MIRT053449)
- hsa-mir-15a-5p (MIRT224965)
- hsa-mir-16-5p (MIRT224966)
- hsa-mir-15b-5p (MIRT224967)
- hsa-mir-195-5p (MIRT224968)
- hsa-mir-424-5p (MIRT224969)
- hsa-mir-497-5p (MIRT224970)
- hsa-mir-646 (MIRT224972)
- hsa-mir-3653-3p (MIRT224973)
- hsa-mir-3674 (MIRT224974)
- hsa-mir-3935 (MIRT224975)
- hsa-mir-4490 (MIRT224977)
- hsa-mir-6838-5p (MIRT224980)
- hsa-mir-369-3p (MIRT224981)
- hsa-mir-625-3p (MIRT224982)
- hsa-mir-3123 (MIRT224984)
- hsa-mir-3925-5p (MIRT224985)
- hsa-mir-6832-5p (MIRT224987)
- hsa-mir-8084 (MIRT224988)
- hsa-mir-3606-5p (MIRT224990)
- hsa-mir-3942-5p (MIRT224991)
- hsa-mir-4703-5p (MIRT224992)
- hsa-mir-653-5p (MIRT322674)
- hsa-mir-466 (MIRT322676)
- hsa-mir-4274 (MIRT322677)
- hsa-mir-3941 (MIRT322678)
- hsa-mir-4643 (MIRT322679)
- hsa-mir-4672 (MIRT322680)
- hsa-mir-4704-3p (MIRT322681)
- hsa-mir-548ao-5p (MIRT322682)
- hsa-mir-5585-5p (MIRT322683)
- hsa-mir-548ax (MIRT322684)
- hsa-mir-8060 (MIRT322685)
- hsa-mir-30a-5p (MIRT322686)
- hsa-mir-30c-5p (MIRT322687)
- hsa-mir-30d-5p (MIRT322688)
- hsa-mir-30b-5p (MIRT322689)
- hsa-mir-30e-5p (MIRT322690)
- hsa-mir-548av-3p (MIRT322694)
- hsa-mir-590-3p (MIRT322697)
- hsa-mir-570-3p (MIRT322703)
- hsa-mir-4803 (MIRT322705)
- hsa-mir-133a-5p (MIRT363790)
- hsa-mir-370-3p (MIRT363791)
- hsa-mir-1976 (MIRT363797)
- hsa-mir-3692-5p (MIRT363800)
- hsa-mir-6893-3p (MIRT363806)
- hsa-mir-429 (MIRT503129)
- hsa-mir-200c-3p (MIRT503130)
- hsa-mir-200b-3p (MIRT503131)
- hsa-mir-548g-3p (MIRT503132)
- hsa-mir-511-5p (MIRT538990)
- hsa-mir-6830-3p (MIRT538991)
- hsa-let-7c-3p (MIRT559263)
- hsa-mir-488-3p (MIRT559264)
- hsa-mir-4781-3p (MIRT559265)
- hsa-mir-4789-3p (MIRT559266)
- hsa-mir-376a-2-5p (MIRT559267)
- hsa-mir-138-5p (MIRT559268)
- hsa-mir-6131 (MIRT559269)
- hsa-mir-7151-5p (MIRT559270)
- hsa-mir-921 (MIRT568312)
- hsa-mir-545-5p (MIRT568313)
- hsa-mir-8080 (MIRT568314)
- hsa-mir-7161-5p (MIRT568315)
- hsa-mir-548u (MIRT568316)
- hsa-mir-6818-3p (MIRT660350)
- hsa-mir-8068 (MIRT660351)
- hsa-mir-1266-3p (MIRT660352)
- hsa-mir-4793-5p (MIRT660353)
- hsa-mir-4776-3p (MIRT660354)
- hsa-mir-6875-3p (MIRT660355)
- hsa-mir-5006-5p (MIRT660356)
- hsa-mir-3972 (MIRT660357)
- hsa-mir-1202 (MIRT660358)
- hsa-mir-3121-5p (MIRT660359)
miRNA Products
- Search ViGene Biosciences for BAG4
Inhibitory RNA Products
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Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for BAG4
-
ViGene Biosciences adenoviral particle packaged cDNA for BAG4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for BAG4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for BAG4 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for BAG4 Gene
Localization for BAG4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for BAG4 Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| nucleus | 5 |
| cytosol | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | 21712384 |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005886 | plasma membrane | IDA | 21712384 |
Pathways & Interactions for BAG4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | TNFR1 Pathway |
.87
.87
.56
|
.55
|
| 2 | TNF signaling (REACTOME) |
.86
|
|
| 3 | FGFR1 mutant receptor activation | ||
| 4 | Cellular response to heat stress | ||
| 5 | HIV Life Cycle |
.45
|
|
Pathways by source for BAG4 Gene
3 BioSystems pathways for BAG4 Gene
12 Reactome pathways for BAG4 Gene
1 KEGG pathway for BAG4 Gene
1 GeneGo (Thomson Reuters) pathway for BAG4 Gene
1 R&D Systems pathway for BAG4 Gene
4 Qiagen pathways for BAG4 Gene
Interacting Proteins for BAG4 Gene
Selected Interacting proteins:
ENSP00000287322
O95429-BAG4_HUMAN
for BAG4 Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006457 | protein folding | TAS | 9873016 |
| GO:0010763 | positive regulation of fibroblast migration | IEA | -- |
| GO:0030838 | positive regulation of actin filament polymerization | IEA | -- |
| GO:0033138 | positive regulation of peptidyl-serine phosphorylation | IEA | -- |
| GO:0033209 | tumor necrosis factor-mediated signaling pathway | TAS | -- |
No data available for SIGNOR curated interactions for BAG4 Gene
Transcripts for BAG4 Gene
mRNA/cDNA for BAG4 Gene
- (2) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (93) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for BAG4 Gene
CRISPR Products
-
OriGene CRISPR knockouts for BAG4
-
Santa Cruz Biotechnology (SCBT) CRISPR for BAG4
- GenScript: Design CRISPR guide RNA sequences for BAG4
miRNA Products
- Search ViGene Biosciences for BAG4
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for BAG4
- Browse OriGene Inhibitory RNA Products For BAG4
-
ViGene Biosciences ready-to-package AAV shRNAs for BAG4 gene
Clone Products
- Sino Biological Human cDNA Clone for BAG4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for BAG4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BAG4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||
| SP4: |
Expression for BAG4 Gene
This gene is overexpressed in Peripheral blood mononuclear cells (36.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for BAG4 Gene
NURSA nuclear receptor signaling pathways regulating expression of BAG4 Gene:
BAG4SOURCE GeneReport for Unigene cluster for BAG4 Gene:
Hs.194726mRNA Expression by UniProt/SwissProt for BAG4 Gene:
O95429-BAG4_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for BAG4 Gene
- Nervous system(4.3)
- Liver(4.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for BAG4
-
OriGene qPCR primer pairs for BAG4
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for BAG4 Gene
Orthologs for BAG4 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | BAG4 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | BAG4 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | BAG4 35 34 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Bag4 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Bag4 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | BAG4 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| chicken (Gallus gallus) |
Aves | BAG4 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | BAG4 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | bag4 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | bag4 35 |
|
OneToOne | |
| wufd20a04 34 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | stv 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.5020 35 |
|
OneToMany |
- Species where no ortholog for BAG4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for BAG4 Gene
Variants for BAG4 Gene
| SNP ID | Clin | Chr 08 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000000268 | -- | 38,176,068(+) | GAGGC(A/T)GCGAG | intron-variant, upstream-variant-2KB | |
| rs1000196726 | -- | 38,194,258(+) | TTTAC(A/G)TGTTT | intron-variant | |
| rs1000204658 | -- | 38,210,743(+) | CACTC(A/C)TTAAA | utr-variant-3-prime | |
| rs1000254934 | -- | 38,177,093(+) | TCCCT(C/T)GGGAG | upstream-variant-2KB, reference, missense | |
| rs1000321098 | -- | 38,211,009(+) | TATAG(-/TAT)TATTC | cds-indel |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv7162n100 | CNV | gain | 25217958 |
| dgv7163n100 | CNV | gain | 25217958 |
| dgv7164n100 | CNV | gain | 25217958 |
| dgv7165n100 | CNV | loss | 25217958 |
| esv3421040 | CNV | insertion | 20981092 |
| esv3430937 | CNV | insertion | 20981092 |
| nsv1117823 | CNV | deletion | 24896259 |
| nsv397579 | CNV | deletion | 16902084 |
| nsv967580 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
77.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.46;
28.49% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for BAG4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- BAG4
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for BAG4 Gene
Disorders for BAG4 Gene
Relevant External Links for BAG4
No disorders were found for BAG4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for BAG4 Gene
Publications for BAG4 Gene
- An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators. (PMID: 9873016) Takayama S. … Reed J.C. (J. Biol. Chem. 1999) 2 3 4 22 64
- Prevention of constitutive TNF receptor 1 signaling by silencer of death domains. (PMID: 9915703) Jiang Y. … Goeddel D.V. (Science 1999) 2 3 4 22 64
- BAG4/SODD protein contains a short BAG domain. (PMID: 12058034) Briknarova K. … Ely K.R. (J. Biol. Chem. 2002) 3 4 22 64
- High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy. (PMID: 24270810) Hasson S.A. … Youle R.J. (Nature 2013) 3 4 64
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 46 64
Products for BAG4 Gene
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- antibodies-online Antibodies for BAG4: See all 116
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- VectorBuilder custom plasmid, inducible vectors for BAG4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for BAG4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for BAG4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer