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BAG2 Gene

protein-coding   GIFtS: 59
GCID: GC06P057084

BCL2-Associated Athanogene 2

  See BAG2-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
BCL2-Associated Athanogene 21 2     BAG-Family Molecular Chaperone Regulator-22
Bcl-2-Associated Athanogene 22 3     dJ417I1.22
BAG-22 3     DJ417I1.2 (BAG-Family Molecular Chaperone Regulator 2)2
BAG Family Molecular Chaperone Regulator 22     

External Ids:    HGNC: 9381   Entrez Gene: 95322   Ensembl: ENSG000001122087   OMIM: 6038825   UniProtKB: O958163   

Export aliases for BAG2 gene to outside databases

Previous GC identifers: GC06P057039 GC06P057083 GC06P057145 GC06P056871


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BAG2 Gene:
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the
BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their
N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3
interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high
affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. (provided
by RefSeq, Jul 2008)

GeneCards Summary for BAG2 Gene:
BAG2 (BCL2-associated athanogene 2) is a protein-coding gene. Diseases associated with BAG2 include spindle cell hemangioma, and brain cancer. GO annotations related to this gene include chaperone binding.

UniProtKB/Swiss-Prot: BAG2_HUMAN, O95816
Function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release

Gene Wiki entry for BAG2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the BAG2 gene promoter:
         AML1a   Lmo2   HNF-4alpha2   HNF-4alpha1   AREB6   POU2F1   POU2F1a   POU2F1b   c-Myb   POU2F1c   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBAG2 promoter sequence
   Search Chromatin IP Primers for BAG2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BAG2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p12.1-p11.2   Ensembl cytogenetic band:  6p11.2   HGNC cytogenetic band: 6p12.3-p11.2

BAG2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BAG2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P057084:  view genomic region     (about GC identifiers)

Start:
57,037,104 bp from pter      End:
57,054,631 bp from pter
Size:
17,528 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: BAG2_HUMAN, O95816 (See protein sequence)
Recommended Name: BAG family molecular chaperone regulator 2  
Size: 211 amino acids; 23772 Da
Subunit: Binds to the ATPase domain of HSP/HSC70 chaperones
Secondary accessions: Q08AS9 Q6FID0

Explore the universe of human proteins at neXtProt for BAG2: NX_O95816

Explore proteomics data for BAG2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys5, Lys123, Lys154, Lys200
  • Modification sites at PhosphoSitePlus

  • See BAG2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004273.1  
    ENSEMBL proteins: 
     ENSP00000359727   ENSP00000441795  

    BAG2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR003103 BAG_domain

    Graphical View of Domain Structure for InterPro Entry O95816

    ProtoNet protein and cluster: O95816

    1 Blocks protein domain: IPB003103 Apoptosis regulator Bcl-2 protein

    UniProtKB/Swiss-Prot: BAG2_HUMAN, O95816
    Similarity: Contains 1 BAG domain


    Find genes that share domains with BAG2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BAG2_HUMAN, O95816
    Function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release

         Genatlas biochemistry entry for BAG2:
    BCL2-associated athanogene 2 (antiapoptotic). Negative regulator of Hsp70 chaperone activity

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18457437
    GO:0051087chaperone binding IEA--
         
    Find genes that share ontologies with BAG2           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for BAG2:
     Decreased viability of wild-ty  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BAG2
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    miRNA
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    miRTarBase miRNAs that target BAG2:
    hsa-mir-181a-5p (MIRT025092), hsa-mir-93-5p (MIRT048797), hsa-mir-128-3p (MIRT021988)

    Block miRNA regulation of human, mouse, rat BAG2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BAG2 (see all 13):
    hsa-miR-140-5p hsa-miR-27a hsa-miR-101* hsa-miR-128 hsa-miR-548e hsa-miR-3681* hsa-miR-548o hsa-miR-3133
    SwitchGear 3'UTR luciferase reporter plasmidBAG2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat BAG2

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    cytoskeleton2
    nucleus2
    extracellular1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for BAG2 About    
    See pathways by source

    SuperPathContained pathways About
    1Regulation of degradation of deltaF508 CFTR in CF
    Regulation of degradation of wt CFTR0.59
    Regulation of degradation of deltaF508 CFTR in CF0.59
    2Protein processing in endoplasmic reticulum
    Protein processing in endoplasmic reticulum


    Find genes that share SuperPaths with BAG2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 GeneGo (Thomson Reuters) Pathways for BAG2
        Regulation of degradation of deltaF508 CFTR in CF
    Regulation of degradation of wt-CFTR



    1 Kegg Pathway  (Kegg details for BAG2):
        Protein processing in endoplasmic reticulum

        Pathway & Disease-focused RT2 Profiler PCR Array including BAG2: 
              Heat Shock Proteins & Chaperones in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for BAG2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for BAG2 (O958161, 2, 3 ENSP000003597274) via UniProtKB, MINT, STRING, and/or I2D (see all 149)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000232804P081072, 3, ENSP000003930874MINT-6735120 I2D: score=2 STRING: ENSP00000393087
    ENSG00000212866P081072, 3MINT-6735120 I2D: score=2 
    ENSG00000215328P081072, 3MINT-6735120 I2D: score=2 
    ENSG00000224501P081072, 3MINT-6735120 I2D: score=2 
    ENSG00000231555P081072, 3MINT-6735120 I2D: score=2 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006457protein folding TAS9873016
    GO:0019538protein metabolic process IDA9873015

    Find genes that share ontologies with BAG2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BAG2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for BAG2 gene: 
    NM_004282.3  

    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370693(uc003pdr.3 uc011dxo.2) ENST00000545080
    miRNA
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    Block miRNA regulation of human, mouse, rat BAG2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BAG2 (see all 13):
    hsa-miR-140-5p hsa-miR-27a hsa-miR-101* hsa-miR-128 hsa-miR-548e hsa-miR-3681* hsa-miR-548o hsa-miR-3133
    SwitchGear 3'UTR luciferase reporter plasmidBAG2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for BAG2
    Predesigned siRNA for gene silencing in human, mouse, rat BAG2
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BAG2
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for BAG2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BAG2
      QuantiTect SYBR Green Assays in human, mouse, rat BAG2
      QuantiFast Probe-based Assays in human, mouse, rat BAG2

    Selected AceView cDNA sequences (see all 211):

    BI494470 BX403369 AI206258 CD519662 CR621395 AU118349 CD742992 AI654091 
    AI372939 AA436583 BX111084 AI680199 AI828270 AI628654 AA938204 BM970449 
    CA427390 BU627661 CA428789 AA993960 AL048064 BU625935 AU140045 CR606486 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for BAG2    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c
    SP1:                                -                                             
    SP2:              -     -     -     -     -                                       
    SP3:              -     -     -     -                                             
    SP4:                                      -                                       
    SP5:                                -     -                                       


    ECgene alternative splicing isoforms for BAG2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BAG2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAATCACGCA
    BAG2 Expression
    About this image


    BAG2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Uterus (Reproductive System)
    BAG2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BAG2 Protein Expression
        Pathway & Disease-focused RT2 Profiler PCR Array including BAG2: 
              Heat Shock Proteins & Chaperones in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BAG2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for BAG2 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Bag21 , 5 BCL2-associated athanogene 21, 5 85.56(n)1
    93.81(a)1
      1 (12.81 cM)5
    2135391  NM_145392.21  NP_663367.11 
     337454845 
    chicken
    (Gallus gallus)
    Aves BAG21 BCL2-associated athanogene 2 77.78(n)
    81.92(a)
      421880  XM_419897.4  XP_419897.4 
    lizard
    (Anolis carolinensis)
    Reptilia BAG26
    BCL2-associated athanogene 2
    70(a)
    1 ↔ 1
    1(162955644-162967463)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.173232 Xenopus laevis transcribed sequence with weak similarity more 71.31(n)    BJ080418.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc641952 similar to Bcl2-associated athanogene 2 72.26(n)   393975  BC053303.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG79451 CG7945 46.47(n)
    40(a)
      39679  NM_140516.3  NP_648773.1 
    worm
    (Caenorhabditis elegans)
    Secernentea unc-231 unc-23 47.37(n)
    40.35(a)
      179272  NM_072906.5  NP_505307.1 


    ENSEMBL Gene Tree for BAG2 (if available)
    TreeFam Gene Tree for BAG2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BAG2 (see all 221)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1492789051,2
    --57035902(+) CTAGGA/TTAAGA 1 -- us2k10--------
    rs1860639471,2
    --57035912(+) AGAGAA/GAAAGA 1 -- us2k10--------
    rs1912876151,2
    --57035955(+) TTTCAA/GACCAC 1 -- us2k10--------
    rs1812308861,2
    --57036441(+) TCTATC/TGCCCA 1 -- us2k10--------
    rs796377621,2
    F--57036608(+) TCGAGG/ACTGCA 1 -- us2k12Minor allele frequency- A:0.06CSA WA 120
    rs1443233781,2
    C--57036880(+) CTTCTA/GTTTCA 1 -- us2k10--------
    rs1853190111,2
    --57037010(+) TTCGCG/TTGGGG 1 -- us2k10--------
    rs1905964771,2
    --57037017(+) GGGGGC/GAGTTG 1 -- us2k10--------
    rs1827288501,2
    --57037019(+) GGGGAA/GTTGGT 1 -- us2k10--------
    rs761197401,2
    C,F--57037488(+) GTCGGA/CGGCTT 1 -- ut511Minor allele frequency- C:0.09WA 118

    HapMap Linkage Disequilibrium report for BAG2 (57037104 - 57054631 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for BAG2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv462949CNV Loss19166990

    Site Specific Mutation Identification with PCR Assays
    1 Copy Number PCR Panel containing BAG2:
    Gastric Cancer
    SeqTarget long-range PCR primers for resequencing BAG2
    DNA2.0 Custom Variant and Variant Library Synthesis for BAG2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603882    OMIM disorders: --

    2 diseases for BAG2:    
    About MalaCards
    spindle cell hemangioma    brain cancer

    1 disease from the University of Copenhagen DISEASES database for BAG2:
    Spindle cell hemangioma

    Find genes that share disorders with BAG2           About GenesLikeMe


    Export disorders for BAG2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BAG2 gene, integrated from 10 sources (see all 59):
    (articles sorted by number of sources associating them with BAG2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators. (PubMed id 9873016)1, 2, 3, 9 Takayama S.... Reed J.C. (J. Biol. Chem. 1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    5. Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro. (PubMed id 24318877)1 Rauch J.N. and Gestwicki J.E. (J. Biol. Chem. 2014)
    6. Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (J. Proteome Res. 2013)
    7. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    8. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    9. Identification of the hypoxia-inducible factor 2I+ nuclear interactome in melanoma cells reveals master proteins involved in melanoma development. (PubMed id 23275444)1 Steunou A.L....Nieto L. (amp 2013)
    10. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. (PubMed id 23349634)1 Cloutier P.... Coulombe B. (PLoS Genet. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9532 HGNC: 938 AceView: BAG2 Ensembl:ENSG00000112208 euGenes: HUgn9532
    ECgene: BAG2 Kegg: 9532 H-InvDB: BAG2

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BAG2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BAG2 gene:
    Search GeneIP for patents involving BAG2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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