Aliases for BACH2 Gene
External Ids for BACH2 Gene
Previous GeneCards Identifiers for BACH2 Gene
GeneCards Summary for BACH2 Gene
BACH2 (BTB Domain And CNC Homolog 2) is a Protein Coding gene. Diseases associated with BACH2 include Leukemia, Chronic Myeloid, Somatic and Lymphoma, Non-Hodgkin. Among its related pathways are NF-kappaB Signaling. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II distal enhancer sequence-specific DNA binding. An important paralog of this gene is GRIK1-AS2.
UniProtKB/Swiss-Prot for BACH2 Gene
Transcriptional regulator that acts as repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 (PubMed:17018862). Positively regulates the nuclear import of actin (By similarity).