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Aliases for BACE1-AS Gene

Subcategory (RNA class) for BACE1-AS Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for BACE1-AS Gene

  • BACE1 Antisense RNA 2 3 5
  • BACE1 Antisense RNA (Non-Protein Coding) 2 3
  • Non-Protein Coding RNA 177 2
  • NCRNA00177 3
  • BACE1-AS1 3
  • BACE1AS 3

External Ids for BACE1-AS Gene

Previous HGNC Symbols for BACE1-AS Gene

  • BACE1AS

Previous GeneCards Identifiers for BACE1-AS Gene

  • GC11U901760
  • GC11P117165

Summaries for BACE1-AS Gene

Entrez Gene Summary for BACE1-AS Gene

  • This gene encodes an unspliced long non-coding RNA transcribed from the opposite strand to BACE1. The encoded transcript is thought to form an RNA duplex with BACE1 mRNA thereby regulating its expression and is also thought to promote post-transcriptional feed-forward regulation of BACE1. This may lead to increased levels of beta amyloid and increased senile plaque deposition, and therefore may play a role in the pathophysiology of Alzheimer's disease. [provided by RefSeq, Jan 2015]

GeneCards Summary for BACE1-AS Gene

BACE1-AS (BACE1 Antisense RNA) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with BACE1-AS include alzheimer disease.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for BACE1-AS Gene

Genomics for BACE1-AS Gene

Genomic Location for BACE1-AS Gene

Chromosome:
11
Start:
117,290,874 bp from pter
End:
117,293,571 bp from pter
Size:
2,698 bases
Orientation:
Plus strand

Genomic View for BACE1-AS Gene

Genes around BACE1-AS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
BACE1-AS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for BACE1-AS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for BACE1-AS Gene

No data available for Regulatory Elements for BACE1-AS Gene

Proteins for BACE1-AS Gene

Post-translational modifications for BACE1-AS Gene

No Post-translational modifications

No data available for DME Specific Peptides for BACE1-AS Gene

Domains & Families for BACE1-AS Gene

Gene Families for BACE1-AS Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with BACE1-AS: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for BACE1-AS Gene

Function for BACE1-AS Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for BACE1-AS Gene

Localization for BACE1-AS Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for BACE1-AS Gene

Pathways & Interactions for BACE1-AS Gene

SuperPathways for BACE1-AS Gene

No Data Available

Interacting Proteins for BACE1-AS Gene

Gene Ontology (GO) - Biological Process for BACE1-AS Gene

None

No data available for Pathways by source and SIGNOR curated interactions for BACE1-AS Gene

Drugs & Compounds for BACE1-AS Gene

No Compound Related Data Available

Transcripts for BACE1-AS Gene

mRNA/cDNA for BACE1-AS Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for BACE1-AS Gene

No ASD Table

Relevant External Links for BACE1-AS Gene

GeneLoc Exon Structure for
BACE1-AS
ECgene alternative splicing isoforms for
BACE1-AS

Expression for BACE1-AS Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for BACE1-AS Gene

Orthologs for BACE1-AS Gene

Evolution for BACE1-AS Gene

ENSEMBL:
Gene Tree for BACE1-AS (if available)
TreeFam:
Gene Tree for BACE1-AS (if available)

No data available for Orthologs for BACE1-AS Gene

Paralogs for BACE1-AS Gene

No data available for Paralogs for BACE1-AS Gene

Variants for BACE1-AS Gene

Structural Variations from Database of Genomic Variants (DGV) for BACE1-AS Gene

Variant ID Type Subtype PubMed ID
nsv509443 CNV Insertion 20534489

Relevant External Links for BACE1-AS Gene

HapMap Linkage Disequilibrium report
BACE1-AS

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for BACE1-AS Gene

Disorders for BACE1-AS Gene

MalaCards: The human disease database

(1) MalaCards diseases for BACE1-AS Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
alzheimer disease
  • alzheimer disease, late-onset
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for BACE1-AS

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
BACE1-AS
genes like me logo Genes that share disorders with BACE1-AS: view

No data available for UniProtKB/Swiss-Prot and Genatlas for BACE1-AS Gene

Publications for BACE1-AS Gene

  1. Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis. (PMID: 21785702) Modarresi F. … Lopez-Toledano M.A. (Int J Alzheimers Dis 2011) 2 3 67
  2. Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. (PMID: 18587408) Faghihi M.A. … Wahlestedt C. (Nat. Med. 2008) 2 3
  3. HuD regulates coding and noncoding RNA to induce APPa89AI^ processing. (PMID: 24857657) Kang M.J. … Gorospe M. (Cell Rep 2014) 3
  4. Attenuated ability of BACE1 to cleave the amyloid precursor protein via silencing long noncoding RNA BACE1a89AS expression. (PMID: 24970022) Liu T. … Chen C. (Mol Med Rep 2014) 3
  5. A long non-coding RNA snaR contributes to 5-fluorouracil resistance in human colon cancer cells. (PMID: 25078450) Lee H. … Lee E.K. (Mol. Cells 2014) 3

Products for BACE1-AS Gene

Sources for BACE1-AS Gene

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