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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

BABAM1 Gene

protein-coding   GIFtS: 49
GCID: GC19P017456

BRISC And BRCA1 A Complex Member 1

(Previous name: chromosome 19 open reading frame 62)
(Previous symbol: C19orf62)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
BRISC And BRCA1 A Complex Member 11 2     Chromosome 19 Open Reading Frame 621
C19orf621 2 3     Mediator Of Rap80 Interactions And Targeting 40 KD1
MERIT402 3 5     BRCA1-A Complex Subunit MERIT402
NBA12 3 5     BRISC And BRCA1-A Complex Member 12
New Component Of The BRCA1 A Complex1 2     Mediator Of Rap80 Interactions And Targeting 40 KDa2
Mediator Of RAP80 Interactions And Targeting Subunit Of 40 KDa2 3     New Component Of The BRCAA1 A Complex2
New Component Of The BRCA1-A Complex2 3     C10orf625

External Ids:    HGNC: 250081   Entrez Gene: 290862   Ensembl: ENSG000001053937   OMIM: 6127665   UniProtKB: Q9NWV83   

Export aliases for BABAM1 gene to outside databases

Previous GC identifer: GC19P017379


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for BABAM1 Gene: 
BABAM1 (BRISC and BRCA1 A complex member 1) is a protein-coding gene. Diseases associated with BABAM1 include ovarian cancer, and breast cancer, and among its related super-pathways are Cell Cycle / Checkpoint Control. GO annotations related to this gene include protein binding. An important paralog of this gene is ENSG00000269307.

UniProtKB/Swiss-Prot: BABA1_HUMAN, Q9NWV8
Function: Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated
histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage
at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically
removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the
complex integrity and its localization at DSBs. Probably also plays a role as a component of the BRISC complex, a
multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. In these 2 complexes, it is probably
required to maintain the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by
BRCC3/BRCC36 component

Gene Wiki entry for BABAM1 (C19orf62) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NT_011295.11  NC_018930.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for BABAM1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBABAM1 promoter sequence
   Search SABiosciences Chromatin IP Primers for BABAM1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BABAM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.11   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p13.11

BABAM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BABAM1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P017456:  view genomic region     (about GC identifiers)

Start:
17,378,159 bp from pter      End:
17,392,058 bp from pter
Size:
13,900 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: BABA1_HUMAN, Q9NWV8 (See protein sequence)
Recommended Name: BRISC and BRCA1-A complex member 1  
Size: 329 amino acids; 36560 Da
Subunit: Component of the BRCA1-A complex, at least composed of the BRCA1, BARD1, UIMC1/RAP80, FAM175A/Abraxas,
BRCC3/BRCC36, BRE/BRCC45 and BABAM1/NBA1. In the BRCA1-A complex, interacts directly with FAM175A/Abraxas and
BRE/BRCC45. Component of the BRISC complex, at least composed of the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and
BABAM1/NBA1
Subcellular location: Cytoplasm. Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs)
Sequence caution: Sequence=AAF29106.1; Type=Frameshift; Positions=263;
Secondary accessions: A8MQT0 B4DRY9 B4DVR1 Q6FIA0 Q9P018
Alternative splicing: 3 isoforms:  Q9NWV8-1   Q9NWV8-2   Q9NWV8-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BABAM1: NX_Q9NWV8

Explore proteomics data for BABAM1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NWV8

  • BABAM1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    BABAM1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001028721.1  NP_054892.2  

    ENSEMBL proteins: 
     ENSP00000471605   ENSP00000469527   ENSP00000352408   ENSP00000472632   ENSP00000473182  
     ENSP00000470920   ENSP00000473240   ENSP00000471721   ENSP00000472425   ENSP00000468834  
     ENSP00000472585   ENSP00000471246   ENSP00000470088   ENSP00000470295   ENSP00000407826  

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    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA19261746
    GO:0005737cytoplasm IDA19261749
    GO:0070531BRCA1-A complex IDA19261746
    GO:0070552BRISC complex IDA19214193

    BABAM1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026126 BABAM1

    Graphical View of Domain Structure for InterPro Entry Q9NWV8

    ProtoNet protein and cluster: Q9NWV8

    UniProtKB/Swiss-Prot: BABA1_HUMAN, Q9NWV8
    Domain: The VWFA-like region is similar to the VWFA domain. Its presence reveals similarities between the
    structure of the 19S proteasome and the BRCA1-A complexes
    Similarity: Belongs to the BABAM1 family


    BABAM1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BABA1_HUMAN, Q9NWV8
    Function: Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated
    histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage
    at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically
    removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the
    complex integrity and its localization at DSBs. Probably also plays a role as a component of the BRISC complex, a
    multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. In these 2 complexes, it is probably
    required to maintain the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by
    BRCC3/BRCC36 component

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16189514
         
    BABAM1 for ontologies           About GeneDecksing


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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for BABAM1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1DNA Damage
    DNA Damage0.32
    Cell Cycle / Checkpoint Control0.32

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 Cell Signaling Technology (CST) Pathways for BABAM1
        Cell Cycle / Checkpoint Control
    DNA Damage



    BABAM1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BABAM1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/633 Interacting proteins for BABAM1 (Q9NWV81, 2, 3 ENSP000003524084) via UniProtKB, MINT, STRING, and/or I2D (see all 633)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BREQ9NXR71, 3, ENSP000003434124EBI-745725,EBI-949389 I2D: score=5 STRING: ENSP00000343412
    LRRC47Q8N1G42, 3, ENSP000003674984MINT-7945693 I2D: score=2 STRING: ENSP00000367498
    PLK1P533502, 3, ENSP000003000934MINT-7945693 I2D: score=2 STRING: ENSP00000300093
    PRKAG1P546192, 3, ENSP000003238674MINT-7945693 I2D: score=2 STRING: ENSP00000323867
    DDX39AO001482, 3, ENSP000002427764MINT-7945693 I2D: score=1 STRING: ENSP00000242776
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006302double-strand break repair IMP19261746
    GO:0010212response to ionizing radiation IMP19261748
    GO:0016568chromatin modification IEA--
    GO:0031572G2 DNA damage checkpoint IMP19261746
    GO:0045739positive regulation of DNA repair IMP19261746

    BABAM1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for BABAM1 (BABA1)

    Search CenterWatch for drugs/clinical trials and news about BABAM1 / BABA1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for BABAM1 gene (2 alternative transcripts): 
    NM_001033549.1  NM_014173.2  

    Unigene Cluster for BABAM1:

    BRISC and BRCA1 A complex member 1
    Hs.190722  [show with all ESTs]
    Unigene Representative Sequence: BM925343
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000598188 ENST00000594247 ENST00000359435(uc010xpl.1 uc002nfu.3 uc002nfv.3 uc010ean.2 uc002nfw.3)
    ENST00000599474 ENST00000599057 ENST00000595393 ENST00000601043 ENST00000601171
    ENST00000596335 ENST00000601436 ENST00000448635 ENST00000595632 ENST00000601938
    ENST00000602066 ENST00000598567 ENST00000598382 ENST00000601232 ENST00000447614

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    Additional mRNA sequence: 

    AF161491.1 AK000578.1 AK025970.1 AK225047.1 AK299493.1 AK301193.1 AK308590.1 AL136692.1 
    BC000788.2 BC006244.1 BC091491.1 CR533526.1 

    24/28 DOTS entries (see all 28):

    DT.452146  DT.100885589  DT.92450285  DT.100885583  DT.95170719  DT.100885576  DT.100038644  DT.121502692 
    DT.121502734  DT.100885594  DT.100885603  DT.92450295  DT.121502644  DT.100885582  DT.91790843  DT.100885579 
    DT.100885598  DT.100885599  DT.100885600  DT.121502676  DT.121502739  DT.91924895  DT.92450298  DT.95170710 

    24/519 AceView cDNA sequences (see all 519):

    AW769515 BF672164 CA435186 CF127051 D55076 BQ053778 BI522825 AA993359 
    BQ050296 BI116070 BM765059 BG482237 AA469095 CR625721 BM669532 CD108560 
    BU174830 BM469106 AA564743 AA363840 BQ231461 BE270851 AA618491 CB157549 

    GeneLoc Exon Structure

    5/16 Alternative Splicing Database (ASD) splice patterns (SP) for BABAM1 (see all 16)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8a · 8b · 8c · 8d · 8e ^ 9a · 9b · 9c ^ 10a ·
    SP1:                                -     -     -                                   -     -     -           -                                                   
    SP2:                          -     -     -     -                                   -     -     -           -                                                   
    SP3:                                -     -                                         -     -     -           -                                                   
    SP4:                          -     -     -                                         -     -     -           -                             -                     
    SP5:                                -     -     -                                   -                                                                           

    ExUns: 10b · 10c · 10d
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for BABAM1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    BABAM1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATAATTTTT
    BABAM1 Expression
    About this image


    See BABAM1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for BABAM1

    SOURCE GeneReport for Unigene cluster: Hs.190722
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for BABAM1 gene from 4/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Babam11 , 5 RIKEN cDNA 5430437P03 gene5
    BRISC and BRCA1 A complex member 11
    82.78(n)1
    90.88(a)1
      8 (34.43 cM)5
    682511  NM_026636.21  NP_080912.21 
     713968555 
    chicken
    (Gallus gallus)
    Aves LOC7766771 BRISC and BRCA1-A complex member 1-like 76.6(n)
    76.73(a)
      776677  XM_001236185.2  XP_001236186.2 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.39082 Xenopus laevis transcribed sequence with moderate similarity more 76.98(n)    CD361317.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.286302 Transcribed sequence with weak similarity to protein more 81.3(n)    AL909931.1 


    ENSEMBL Gene Tree for BABAM1 (if available)
    TreeFam Gene Tree for BABAM1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for BABAM1 gene
    ENSG000002693072  

    BABAM1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/352 SNPs in BABAM1 are shown (see all 352)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs129808121,2
    C,F--17377558(+) CCCAGC/GTACTT 2 -- us2k18Minor allele frequency- G:0.36NA WA 250
    rs72502661,2
    C,F,H--17377612(+) gcagtC/Gtagtt 2 -- us2k122Minor allele frequency- G:0.11NS EA NA CSA WA 2752
    rs1498042801,2
    --17377636(+) GATACC/TCTGTC 2 -- us2k10--------
    rs1457372251,2
    --17377770(+) TATATG/TTAAAA 2 -- us2k10--------
    rs1150408071,2
    C,F--17377903(+) TTCCCT/CAAATC 2 -- us2k11Minor allele frequency- C:0.04WA 118
    rs1485315291,2
    --17377904(+) TCCCTA/GAATCG 2 -- us2k10--------
    rs1919964311,2
    --17378008(+) TGATTC/TGGCCA 2 -- us2k10--------
    rs1379698981,2
    C--17378018(+) AAAAC-/AAAAAA 2 -- us2k10--------
    rs1434271741,2
    --17378065(+) TTGCTA/CCAGTG 2 -- us2k10--------
    rs1119053451,2
    F--17378095(+) TCCCGG/CCGCAC 2 -- us2k11Minor allele frequency- C:0.50CSA 2

    HapMap Linkage Disequilibrium report for BABAM1 (17378159 - 17392058 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/13 variations for BABAM1 (see all 13):    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv911199CNV Loss21882294
    dgv3760n71CNV Loss21882294
    nsv911182CNV Loss21882294
    dgv3757n71CNV Loss21882294
    nsv911198CNV Loss21882294
    nsv515965CNV Loss19592680
    nsv911188CNV Loss21882294
    nsv911185CNV Loss21882294
    nsv911200CNV Loss21882294
    nsv470129CNV Loss18288195


    Human Gene Mutation Database (HGMD): BABAM1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing BABAM1
    DNA2.0 Custom Variant and Variant Library Synthesis for BABAM1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612766    OMIM disorders: --

    2 diseases for BABAM1:    About MalaCards
    ovarian cancer    breast cancer


    BABAM1 for disorders           About GeneDecksing


    Export disorders for BABAM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for BABAM1 gene, integrated from 9 sources (see all 50):
    (articles sorted by number of sources associating them with BABAM1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (2000)
    2. MERIT40 facilitates BRCA1 localization and DNA damage repair. (PubMed id 19261748)1, 2 Feng L.... Chen J. (2009)
    3. MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks. (PubMed id 19261746)1, 2 Shao G.... Greenberg R.A. (2009)
    4. NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control. (PubMed id 19261749)1, 2 Wang B.... Elledge S.J. (2009)
    5. K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC- associated Brcc36 and proteasomal Poh1. (PubMed id 19214193)1, 2 Cooper E.M....Cohen R.E. (2009)
    6. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    7. Genome-wide association study in BRCA1 mutation carrie rs identifies novel loci associated with breast and ovarian cancer risk. (PubMed id 23544013)1 Couch F.J....Antoniou A.C. (2013)
    8. GWAS meta-analysis and replication identifies three ne w susceptibility loci for ovarian cancer. (PubMed id 23535730)1 Pharoah P.D....Sellers T.A. (2013)
    9. Genome-wide association studies identify four ER negat ive-specific breast cancer risk loci. (PubMed id 23535733)1 Garcia-Closas M....Kraft P. (2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29086 HGNC: 25008 AceView: HSPC142 Ensembl:ENSG00000105393 euGenes: HUgn29086
    ECgene: BABAM1 H-InvDB: BABAM1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for BABAM1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for BABAM1 gene:
    Search GeneIP for patents involving BABAM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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