BAAT Gene
protein-coding GIFtS: 59
GCID: GC09M104122
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bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)(Previous name: bile acid Coenzyme A: amino acid N-acyltransferase (glycine...)
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Aliases
for BAAT gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Bile Acid CoA: Amino Acid N-Acyltransferase (GlycineN-Choloyltransferase)1 2 | | Bile Acid-CoA:Amino Acid N-Acyltransferase2 | | BAT1 2 3 | | EC 2.3.1.653 | | Bile Acid Coenzyme A: Amino Acid N-Acyltransferase (GlycineN-Choloyltransferase)1 2 | | EC 3.1.2.23 | | Long-Chain Fatty-Acyl-CoA Hydrolase2 3 | | Glycine N-Choloyltransferase3 | | BACAT2 3 | | |
Export aliases for BAAT gene to outside databasesPrevious GC identifers: GC09M094924 GC09M095867 GC09M097581 GC09M099503 GC09M099502 GC09M101202 GC09M103162 GC09M073722 |
Summaries
for BAAT gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for BAAT:
The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoAthioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bileacid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitaminabsorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding thesame protein have been found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: BAAT_HUMAN, Q14032Function: Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bileare cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester,either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmicreticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. Theconjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-solublevitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to theliver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellularlevels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to thefree fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs
Gene Wiki entry for BAAT
|
Genomic Views
for BAAT gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008470.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BAAT gene promoter:
Egr-3 CREB deltaCREB
Other transcription factors
Search SABiosciences Chromatin IP Primers for BAAT
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BAAT |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q22.3 Ensembl cytogenetic band: 9q31.1 HGNC cytogenetic band: 9q22.3BAAT Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M104122: view genomic region
(about GC identifiers)
Start:
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104,122,699 bp from pter |
End:
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104,147,287 bp from pter |
Size:
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24,589 bases |
Orientation:
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minus strand |
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Proteins
for BAAT gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BAAT_HUMAN, Q14032 (See
protein sequence)Recommended Name: Bile acid-CoA:amino acid N-acyltransferase Size: 418 amino acids; 46299 Da
Subunit: Monomer
Subcellular location: Cytoplasm
Miscellaneous: In human, more than 95% of the biliary bile acids are N-acyl amidates with glycine and taurine. In othermammalian species large differences are observed in the relative amounts of taurine- and glycine-conjugated bile acidsformed in bile
Secondary accessions: Q3B7W9 Q96L31Explore the universe of human proteins at neXtProt for BAAT: NX_Q14032
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q14032
BAAT Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001121082.1 NP_001692.1
ENSEMBL proteins: ENSP00000378491 ENSP00000259407 Reactome Protein details: Q14032
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
BAAT for ontologies About GeneDecksing
BAAT Antibody Products:
Assay Products for BAAT: |
Protein
Domains /
Families
for BAAT gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BAAT for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q14032ProtoNet protein and cluster: Q14032 UniProtKB/Swiss-Prot: BAAT_HUMAN, Q14032Similarity: Belongs to the C/M/P thioester hydrolase family |
Function
for BAAT gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: BAAT_HUMAN, Q14032Function: Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bileare cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester,either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmicreticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. Theconjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-solublevitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to theliver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellularlevels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to thefree fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAsCatalytic activity: Choloyl-CoA + glycine = CoA + glycocholateCatalytic activity: Palmitoyl-CoA + H(2)O = CoA + palmitateBiophysicochemical properties: Kinetic parameters: KM=1.1 mM for taurine toward choloyl-CoA; KM=2.2 mM for2-fluoro-beta-alanine toward choloyl-CoA; KM=5.8 mM for glycine toward choloyl-CoA; KM=19.3 uM for arachidoyl-CoA;Vmax=0.33 umol/min/mg enzyme with taurine as substrate for acyltransferase activity; Vmax=0.19 umol/min/mg enzyme with2-fluoro-beta-alanine as substrate for acyltransferase activity; Vmax=0.77 umol/min/mg enzyme with glycine assubstrate for acyltransferase activity; Vmax=223 nmol/min/mg enzyme with arachidoyl-CoA as substrate for acyl-CoAthioesterase activity; Genatlas biochemistry entry for BAAT:bile acid-CoA
Enzyme Numbers (IUBMB): EC 3.1.2.21 EC 2.3.1.651
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BAAT (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BAAT (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): BAAT (NM_001701) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BAAT | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BAAT |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BAAT |
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8): About this table
BAAT for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for BAAT:
|
Pathways & Interactions
for BAAT gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Synthesis of bile acids and bile salts | | | 2 | Metabolism | | | 3 | Drug Induction of Bile Acid Pathway | | | 4 | Bile secretion | | | 5 | Peroxisome | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3  BioSystems Pathways for BAAT
5/6 
Reactome Pathways for BAAT (see all 6)
5/6 
Kegg Pathways (Kegg details for BAAT) (see all 6):
BAAT for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for BAAT
STRING Interaction
Network Preview (showing 5 interactants - click image to see 12)
5/12 Interacting proteins for BAAT (Q140323 ENSP000002594074) via UniProtKB, MINT, STRING, and/or I2D (see all 12)About this table
Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table
BAAT for ontologies About GeneDecksing
|
Drugs & Compounds
for BAAT gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
BAAT for compounds About GeneDecksing
 Browse Tocris compounds for BAAT
10/74 HMDB Compounds for BAAT (see all 74) About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| (2E)-Decenoyl-CoA | (E)-S-2-decenoate Coenzyme A (see all 15) | 10018-95-8 | -- | | (2E)-Dodecenoyl-CoA | 2-trans-Dodecenoyl-Coenzyme A (see all 4) | 1066-12-2 | -- | | (2E)-Hexadecenoyl-CoA | trans-2-Hexadecenoyl-CoA (see all 4) | 4460-95-1 | -- | | (2E)-Octenoyl-CoA | (E)-S-2-octenoate Coenzyme A (see all 16) | 10018-94-7 | -- | | (2E)-Tetradecenoyl-CoA | (2E)-Tetradecenoyl-Coenzyme A (see all 8) | 38795-33-4 | -- | | 11'-Carboxy-alpha-chromanol | 2,5,7,8-Tetramethyl-2-(4',8'-dimethyl-11'-carboxy-undecyl)-6-chromanol;RRR-11'-carboxy-alpha-chromanol;2-(11-carboxy-4,8-dimethylundecyl)-6-hydroxy-2,5,7,8-tetramethylchroman;11'-carboxy-alpha-tocopherol | -- | -- | | 11'-Carboxy-alpha-tocotrienol | alpha-CDMD(en)(2)HC;2-(10-carboxy-4,8-dimethyl-(3E,7E)-decadienyl)-6-hydroxy-2,5,7,8-tetramethylchroman;alpha-CDMD(en)(,2)HC | -- | -- | | 11'-Carboxy-gama-chromanol | 2,7,8-trimethyl-2-(11'-carboxy-4',8'-dimethylundecyl)-6-chromanol;2,7,8-trimethyl-2-(11'-carboxy-4',8'-dimethylundecyl)-6-hydroxychroman;RRR-11'-carboxy-gama-chromanol;11'-Carboxy-gama-tocopherol | -- | -- | | 11'-carboxy-gama-tocotrienol | gama-CDMD(en)(2)HC;carboxydimethyldecadienyl hydroxychroman;2-(10-carboxy-4,8-dimethyl-(3E,7E)-decadienyl)-6-hydroxy-2,7,8-trimethylchroman | -- | -- | | 13'-carboxy-alpha-tocotrienol | 13AaTE | -- | -- |
1 DrugBank Compound for BAAT About this table
1 Novoseek chemical compound relationship for BAAT gene About this table
Search CenterWatch for drugs/clinical trials and news about BAAT
|
Transcripts
for BAAT gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for BAAT gene (2 alternative transcripts): NM_001127610.1 NM_001701.3 Unigene Cluster for BAAT: Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) Hs.284712 [show with all ESTs]Unigene Representative Sequence: NM_0017012 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000395051 ENST00000259407(uc010mtd.3 uc004bbd.4)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BAAT (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BAAT (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): BAAT (NM_001701) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for BAAT | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BAAT |
Additional cDNA sequence: AK315347.1 BC009567.1 BC039200.1 BC107424.1 CR541918.1 L34081.1 4 DOTS entries: DT.405378 DT.92463991 DT.121206343 DT.100783415 24/53 AceView cDNA sequences (see all 53): BX107922 AA778222 CB154124 L34081 CR541918 H91396 NM_001701 BQ681322 BM052974 CB161998 BG616763 BG616473 BM052699 H54740 BG617512 BX951462 AA693547 AI033825 CB154234 R98624 AV692958 BG617062 BC009567 CB164511
GeneLoc Exon Structure
|
Expression
for BAAT gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| BAAT expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATCCAATTAA
About this image
See BAAT Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for BAAT
SOURCE GeneReport for Unigene cluster: Hs.284712
UniProtKB/Swiss-Prot: BAAT_HUMAN, Q14032Tissue specificity: Expressed in liver, gallbladder mucosa and pancreas
SABiosciences Expression via Pathway-Focused PCR Array including BAAT:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BAAT
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat BAAT | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BAAT | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BAAT | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BAAT |
Orthologs
for BAAT gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for BAAT gene from 4/13 species (see all 13) About this table
ENSEMBL Gene Tree for BAAT (if available)
TreeFam Gene Tree for BAAT (if available) |
Paralogs
for BAAT gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for BAAT gene
- ACOT62 ACOT42 ACOT22 ACOT12
3 SIMAP similar genes for BAAT using alignment to 1 protein entry: BAAT_HUMAN:ACOT4 ACOT2 ACOT1
BAAT for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for BAAT
PGOHUM00000248227 PGOHUM00000236286
|
Genomic Variants
for BAAT gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for BAAT (104122699 - 104147287 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for BAAT
1 CNV: 36898
Human Gene Mutation Database (HGMD): BAAT
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BAAT |
|
Disorders
/ Diseases
for BAAT gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BAAT for disorders About GeneDecksing
OMIM gene information: 602938
OMIM disorders: 607748
UniProtKB/Swiss-Prot: BAAT_HUMAN, Q14032
Defects in BAAT are involved in familial hypercholanemia (FHCA) [MIM:607748]. FHCA is a disorder characterizedby elevated serum bile acid concentrations, itching, and fat malabsorption
11  diseases for BAAT: About MalaCardshypercholanemia hypercholanemia, familial botulism primary hyperparathyroidism
intrahepatic cholangiocarcinoma hyperparathyroidism cholangiocarcinoma hepatocellular carcinoma
cholesterol carcinoma sepsis
Human Genome Epidemiology (HuGE) Navigator: BAAT (3 documents)
Export disorders for BAAT gene to outside databases
|
Publications
for BAAT gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for BAAT gene, integrated from 9 sources (see all 34):
(articles sorted by number of sources associating them with BAAT) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human and rat bile acid-CoA:amino acid N-acyltransferase are liver-specific peroxisomal enzymes: implications for intracellular bile salt transport. (PubMed id 17256745)1, 7, 9 Pellicoro A....Faber K.N. (2007)
- Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT. (PubMed id 12704386)1, 2, 9 Carlton V.E.H.... Bull L.N. (2003)
- The human bile acid-CoA:amino acid N-acyltransferase functions in the conjugation of fatty acids to glycine. (PubMed id 12810727)1, 2, 9 O'Byrne J.... Alexson S.E. (2003)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Conserved residues in the putative catalytic triad of human bile acid Coenzyme A:amino acid N-acyltransferase. (PubMed id 12239217)1, 2 Sfakianos M.K.... Barnes S. (2002)
- Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase. (PubMed id 8034703)1, 2 Falany C.N.... Diasio R.B. (1994)
- Purification and characterization of bile acid-CoA:amino acid N- acyltransferase from human liver. (PubMed id 2037576)1, 2 Johnson M.R.... Diasio R.B. (1991)
- Genetic polymorphism of bile acid CoA: amino acid N-acyltransferase in Japanese individuals. (PubMed id 17495420)1, 9 Tougou K....Azuma J. (2007)
- Diagnosis in bile acid-CoA: amino acid N-acyltransfera se deficiency. (PubMed id 22783059)1 Hadzic N....Knisely A.S. (2012)
|
External Searches for BAAT gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BAAT gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BAAT gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing BAAT gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for BAAT | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/BAAT |
|
| | |
About This Section
| Patent Information for BAAT gene:
Search GeneIP for patents involving BAAT
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BAAT gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | OriGene Antibodies for BAAT | | OriGene shRNA RFP for BAAT | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for BAAT | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for BAAT | | | OriGene Protein Over-expression Lysate for BAAT | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for BAAT | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for BAAT | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for BAAT | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for BAAT | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for BAAT | | OriGene Custom Protein Services for BAAT | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat BAAT | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing BAAT | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat BAAT | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat BAAT | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat BAAT | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat BAAT |
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| | | | Search Tocris compounds for BAAT |
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 | | | BAAT Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BAAT |
|  |  |  | | | | ThermoFisher Antibodies for BAAT |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BAAT |
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