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BAALC Gene

protein-coding   GIFtS: 53
GCID: GC08P104152

Brain And Acute Leukemia, Cytoplasmic

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Brain And Acute Leukemia, Cytoplasmic1 2
Brain And Acute Leukemia Cytoplasmic Protein2

External Ids:    HGNC: 143331   Entrez Gene: 798702   Ensembl: ENSG000001649297   OMIM: 6066025   UniProtKB: Q8WXS33   

Export aliases for BAALC gene to outside databases

Previous GC identifers: GC08P103158 GC08P104221 GC08P103821 GC08P104109 GC08P104222 GC08P099353


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for BAALC Gene:
This gene was identified by gene expression studies in patients with acute myeloid leukemia (AML). The gene is
conserved among mammals and is not found in lower organisms. Tissues that express this gene develop from the
neuroectoderm. Multiple alternatively spliced transcript variants that encode different proteins have been
described for this gene; however, some of the transcript variants are found only in AML cell lines. (provided by
RefSeq, Jul 2008)

GeneCards Summary for BAALC Gene:
BAALC (brain and acute leukemia, cytoplasmic) is a protein-coding gene. Diseases associated with BAALC include mn1, and cytogenetically normal acute myeloid leukemia.

UniProtKB/Swiss-Prot: BAALC_HUMAN, Q8WXS3
Function: May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NC_018919.2  NT_008046.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the BAALC gene promoter:
         AML1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidBAALC promoter sequence
   Search Chromatin IP Primers for BAALC

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat BAALC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q22.3   Ensembl cytogenetic band:  8q22.3   HGNC cytogenetic band: 8q22.3

BAALC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
BAALC gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P104152:  view genomic region     (about GC identifiers)

Start:
104,152,921 bp from pter      End:
104,242,533 bp from pter
Size:
89,613 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: BAALC_HUMAN, Q8WXS3 (See protein sequence)
Recommended Name: Brain and acute leukemia cytoplasmic protein  
Size: 180 amino acids; 19224 Da
Subunit: Interacts with CAMK2A (By similarity)
Secondary accessions: Q8WTP6 Q8WXS0 Q8WXS1 Q8WXS2 Q9HA93
Alternative splicing: 6 isoforms:  Q8WXS3-1   Q8WXS3-2   Q8WXS3-3   Q8WXS3-4   Q8WXS3-5   Q8WXS3-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for BAALC: NX_Q8WXS3

Explore proteomics data for BAALC at MOPED

Post-translational modifications: 

  • Palmitoylation and myristoylation target the protein to the lipid rafts (By similarity)1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See BAALC Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001019543.1  NP_079088.1  

    ENSEMBL proteins: 
     ENSP00000312457   ENSP00000395024   ENSP00000297574   ENSP00000302559   ENSP00000331579  

    BAALC Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for BAALC
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    Novus Biologicals BAALC Proteins
    Novus Biologicals BAALC Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for BAALC
    Cloud-Clone Corp. Proteins for BAALC

    BAALC Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of BAALC
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    Abcam antibodies for BAALC
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    ThermoFisher Antibodies for BAALC
    LSBio Antibodies in human, mouse, rat for BAALC

    BAALC Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for BAALC
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for BAALC
    Cloud-Clone Corp. CLIAs for BAALC


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR009728 BAALC

    Graphical View of Domain Structure for InterPro Entry Q8WXS3

    ProtoNet protein and cluster: Q8WXS3


    BAALC for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: BAALC_HUMAN, Q8WXS3
    Function: May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for BAALC:

     High actin ratio cells 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for BAALC
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for BAALC

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for BAALC
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for BAALC

    miRNA
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    Block miRNA regulation of human, mouse, rat BAALC using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BAALC (see all 12):
    hsa-miR-323-3p hsa-miR-4311 hsa-miR-186* hsa-miR-513a-5p hsa-miR-1233 hsa-miR-370 hsa-miR-629 hsa-miR-514
    SwitchGear 3'UTR luciferase reporter plasmidBAALC 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for BAALC
    Predesigned siRNA for gene silencing in human, mouse, rat BAALC

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for BAALC

    Clone
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    OriGene clones in human, mouse for BAALC (see all 12)
    OriGene ORF clones in mouse, rat for BAALC
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): BAALC (NM_024812)
    Sino Biological Human cDNA Clone for BAALC
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BAALC
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BAALC

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for BAALC 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BAALC


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    BAALC_HUMAN, Q8WXS3: Cytoplasm. Membrane. Note=Postsynaptic lipid rafts (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton4
    nucleus4
    cytosol3
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005737cytoplasm IDA11707601
    GO:0005813centrosome ----
    GO:0016020membrane IEA--

    BAALC for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including BAALC: 
              Leukemia in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for BAALC

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for BAALC (Q8WXS32, 3 ENSP000003124574) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MDFIQ997502, 3, ENSP000002303214MINT-67748 I2D: score=5 STRING: ENSP00000230321
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for BAALC



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for BAALC gene (2 alternative transcripts): 
    NM_001024372.1  NM_024812.2  

    Unigene Cluster for BAALC:

    Brain and acute leukemia, cytoplasmic
    Hs.533446  [show with all ESTs]
    Unigene Representative Sequence: NM_024812
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000309982(uc003yld.3 uc003yle.3) ENST00000438105(uc010mcc.3)
    ENST00000297574 ENST00000306391 ENST00000330955 ENST00000519507 ENST00000517863
    ENST00000523754 ENST00000521926
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat BAALC using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate BAALC (see all 12):
    hsa-miR-323-3p hsa-miR-4311 hsa-miR-186* hsa-miR-513a-5p hsa-miR-1233 hsa-miR-370 hsa-miR-629 hsa-miR-514
    SwitchGear 3'UTR luciferase reporter plasmidBAALC 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for BAALC
    Predesigned siRNA for gene silencing in human, mouse, rat BAALC
    Clone
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    OriGene clones in human, mouse for BAALC (see all 12)
    OriGene ORF clones in mouse, rat for BAALC
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): BAALC (NM_024812)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for BAALC
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat BAALC
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for BAALC
    OriGene qSTAR qPCR primer pairs in human, mouse for BAALC
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BAALC
      QuantiTect SYBR Green Assays in human, mouse, rat BAALC
      QuantiFast Probe-based Assays in human, mouse, rat BAALC

    Additional mRNA sequence: 

    AF371319.1 AF371323.1 AK022077.1 AK093819.1 AK310816.1 BC011517.1 BC014365.1 BC035038.2 

    10 DOTS entries:

    DT.443046  DT.95092573  DT.91918803  DT.100778235  DT.121479093  DT.121479250  DT.426517  DT.95092568 
    DT.95092571  DT.95092599 

    Selected AceView cDNA sequences (see all 227):

    F03529 BQ672359 CR597062 CA416942 BM509802 R40778 BQ882252 F05239 
    CB054175 BM717611 F02839 R37607 AI186236 AK093819 CR607637 CR613048 
    T33369 BM682059 AI869984 CA424634 BQ575423 CB155015 Z45132 BQ447214 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for BAALC    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c
    SP1:              -     -     -     -                     
    SP2:                          -                           
    SP3:              -     -                                 
    SP4:                          -     -                     


    ECgene alternative splicing isoforms for BAALC

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    BAALC expression in normal human tissues (normalized intensities)      BAALC embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATGTATGAG
    BAALC Expression
    About this image


    BAALC expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Cerebral Cortex
     
     Fibroblasts
             Detroit 551
     
     Epidermis (Integumentary System)
             Detroit 551
     
     Ovary (Reproductive System)
             Cumulus Cells Antral Follicle
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
    BAALC Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    BAALC Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.533446

    UniProtKB/Swiss-Prot: BAALC_HUMAN, Q8WXS3
    Tissue specificity: Expressed by neural and hematopoietic cells. Expression is found both in normal early
    progenitor cells and in the most immature type of blasts in acute leukemia but not in mature hematopoietic cells.
    Isoform 2 and isoform 6 are expressed in the brain. Isoform 2 shows a low expression in neuroectoderm-derived
    tissues such as adrenal gland and no expression in bone marrow, peripheral blood lymphocytes or lymph nodes, or
    in tumors or cancer cell lines of nonneural tissue origin

        Pathway & Disease-focused RT2 Profiler PCR Array including BAALC: 
              Leukemia in human mouse rat

    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat BAALC
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    QuantiFast Probe-based Assays in human, mouse, rat BAALC
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for BAALC

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for BAALC gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Baalc1 , 5 brain and acute leukemia, cytoplasmic1, 5 86.44(n)1
    83.45(a)1
      15 (15.18 cM)5
    1184521  NM_080640.51  NP_542371.11 
     389331425 
    chicken
    (Gallus gallus)
    Aves BAALC1 brain and acute leukemia, cytoplasmic 66.18(n)
    56.52(a)
      420261  XM_418371.4  XP_418371.2 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia baalc1 brain and acute leukemia, cytoplasmic 57.58(n)
    55.24(a)
      100490693  XM_002931535.2  XP_002931581.2 
    zebrafish
    (Danio rerio)
    Actinopterygii BAALC6
    brain and acute leukemia, cytoplasmic
    32(a)
    1 ↔ 1
    20(19651995-19662538) ENSDARG00000089549


    ENSEMBL Gene Tree for BAALC (if available)
    TreeFam Gene Tree for BAALC (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for BAALC (see all 1476)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1413480771,2
    --104155586(+) AACAGC/TCCCCA 2 -- int10--------
    rs1839397591,2
    --104155655(+) TTCTGA/GTGGGA 2 -- int10--------
    rs13911181,2
    C,F,A,H--104155852(+) TTTACC/TCTCAG 2 -- int124Minor allele frequency- T:0.28NS EA NA WA 2474
    rs1886178411,2
    --104155959(+) CTAGGC/GGAGAA 2 -- int10--------
    rs1807503641,2
    --104155975(+) TTCATA/CTTTGC 2 -- int10--------
    rs13536291,2
    C,F,A,H--104155996(+) CTGAAC/TACATC 2 -- int111Minor allele frequency- T:0.27EA NS WA NA CSA 651
    rs625276081,2
    F--104156001(+) CACATC/GTGGGA 2 -- int12Minor allele frequency- G:0.11NA 122
    rs1836230561,2
    --104156037(+) GATGCG/TCTGTC 2 -- int10--------
    rs625276091,2
    C,F--104156038(+) ATGCTC/GTGTCT 2 -- int12Minor allele frequency- G:0.04NA 122
    rs1503685641,2
    C--104156141(+) TTAGCC/GTGAAT 2 -- int10--------

    HapMap Linkage Disequilibrium report for BAALC (104152921 - 104242533 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for BAALC:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2678140CNV Deletion23128226
    nsv831413CNV Gain17160897
    esv21700CNV Gain19812545

    Human Gene Mutation Database (HGMD): BAALC
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing BAALC
    DNA2.0 Custom Variant and Variant Library Synthesis for BAALC

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606602    OMIM disorders: --

    11 diseases for BAALC:    About MalaCards
    mn1    cytogenetically normal acute myeloid leukemia    acute leukemia    myeloid leukemia
    acute myeloid leukemia    leukemia    chronic myeloid leukemia    myelodysplastic syndromes
    acute promyelocytic leukemia    lymphoblastic leukemia    endotheliitis

    1 disease from the University of Copenhagen DISEASES database for BAALC:
    Leukemia

    BAALC for disorders           About GeneDecksing

    Genetic Association Database (GAD): BAALC

    Export disorders for BAALC gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for BAALC gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with BAALC)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia. (PubMed id 11707601)1, 2, 3 Tanner S.M.... de La Chapelle A. (Proc. Natl. Acad. Sci. U.S.A. 2001)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. BAALC and WT1 expressions from diagnosis to hematopoietic stem cell transplantation: consecutive monitoring in adult patients with core-binding-factor-positive AML. (PubMed id 23672350)1 Yoon J.H....Lim J.H. (Eur. J. Haematol. 2013)
    5. Development and application of a DNA microarray-based yeast two-hybrid system. (PubMed id 23275563)1 Suter B....Wanker E.E. (Nucleic Acids Res. 2013)
    6. In acute promyelocytic leukemia (APL) low BAALC gene expression identifies a patient group with favorable overall survival and improved relapse free survival. (PubMed id 23287429)1 Nolte F....Lengfelder E. (Leuk. Res. 2013)
    7. BAALC overexpression retains its negative prognostic role across all cytogenetic risk groups in acute myeloid leukemia patients. (PubMed id 23760853)1 Damiani D....Damante G. (Am. J. Hematol. 2013)
    8. Prognostic implication of BAALC gene expression in adult acute myeloid leukemia. (PubMed id 23865362)1 Yahya R.S....Sharaf-Eldein M.A. (Clin. Lab. 2013)
    9. miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia. (PubMed id 22529287)1 Eisfeld A.K....Bloomfield C.D. (Blood 2012)
    10. Histone post-translational modifications associated to BAALC expression in leukemic cells. (PubMed id 22197554)1 Franzoni A....Damante G. (Biochem. Biophys. Res. Commun. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79870 HGNC: 14333 AceView: BAALC Ensembl:ENSG00000164929 euGenes: HUgn79870
    ECgene: BAALC H-InvDB: BAALC

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for BAALC Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for BAALC Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for BAALC gene:
    Search GeneIP for patents involving BAALC

    GeneCards and IP:
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