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B9D1 Gene

protein-coding   GIFtS: 46
GCID: GC17M019244

B9 Protein Domain 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
B9 Protein Domain 11 2     MKS92 5
MKSR12 3 5     B92
Endothelial Precursor Protein B91 2     EPPB92
MKS1-Related Protein 12 3     B9 Domain-Containing Protein 12

External Ids:    HGNC: 241231   Entrez Gene: 270772   Ensembl: ENSG000001086417   OMIM: 6141445   UniProtKB: Q9UPM93   

Export aliases for B9D1 gene to outside databases

Previous GC identifers: GC17M019188 GC17M018626


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for B9D1 Gene:
This gene encodes a B9 domain-containing protein, one of several that are involved in ciliogenesis. Alterations in
expression of this gene have been found in a family with Meckel syndrome. Meckel syndrome has been associated
with at least six different genes. This gene is located within the Smith-Magenis syndrome region on chromosome
17. Three alternatively spliced transcript variants that encode different proteins have been described for this
gene. (provided by RefSeq, Aug 2011)

GeneCards Summary for B9D1 Gene:
B9D1 (B9 protein domain 1) is a protein-coding gene. Diseases associated with B9D1 include b9d1-related meckel syndrome, and meckel syndrome 9. GO annotations related to this gene include hedgehog receptor activity. An important paralog of this gene is B9D2.

UniProtKB/Swiss-Prot: B9D1_HUMAN, Q9UPM9
Function: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and
acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.
Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010718.17  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the B9D1 gene promoter:
         AML1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): B9D1 promoter sequence
   Search Chromatin IP Primers for B9D1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat B9D1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p11.2   Ensembl cytogenetic band:  17p11.2   HGNC cytogenetic band: 17p11.2

B9D1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B9D1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M019244:  view genomic region     (about GC identifiers)

Start:
19,240,867 bp from pter      End:
19,281,495 bp from pter
Size:
40,629 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: B9D1_HUMAN, Q9UPM9 (See protein sequence)
Recommended Name: B9 domain-containing protein 1  
Size: 204 amino acids; 22775 Da
Subunit: Part of the tectonic-like complex (also named B9 complex) (By similarity)
Secondary accessions: Q9BU22
Alternative splicing: 2 isoforms:  Q9UPM9-1   Q9UPM9-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for B9D1: NX_Q9UPM9

Explore proteomics data for B9D1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys180
  • Modification sites at PhosphoSitePlus

  • See B9D1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001230402.1  NP_001230404.1  NP_056496.1  

    ENSEMBL proteins: 
     ENSP00000459857   ENSP00000433359   ENSP00000378977   ENSP00000261499   ENSP00000460939  
     ENSP00000378978   ENSP00000458525   ENSP00000268841   ENSP00000410835   ENSP00000462565  
     ENSP00000463165   ENSP00000463255  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR010796 B9_dom

    Graphical View of Domain Structure for InterPro Entry Q9UPM9

    ProtoNet protein and cluster: Q9UPM9

    UniProtKB/Swiss-Prot: B9D1_HUMAN, Q9UPM9
    Similarity: Belongs to the B9D family
    Similarity: Contains 1 B9 domain


    B9D1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: B9D1_HUMAN, Q9UPM9
    Function: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and
    acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.
    Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008158hedgehog receptor activity ISS--
         
    B9D1 for ontologies           About GeneDecksing


    Phenotypes:
         Selected MGI mutant phenotypes (inferred from 3 alleles(MGI details for B9d1) (see all 20):
     adipose tissue  behavior/neurological  cardiovascular system  craniofacial  digestive/alimentary 
     embryogenesis  endocrine/exocrine gland  growth/size/body  hematopoietic system  homeostasis/metabolism 
     immune system  integument  limbs/digits/tail  liver/biliary system  mortality/aging 

    B9D1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out B9d1tm1d(EUCOMM)Wtsi for B9D1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for B9D1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for B9D1
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    B9D1_HUMAN, Q9UPM9: Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme.
    Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    extracellular3
    cytosol1
    nucleus1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005813centrosome IDA19208769
    GO:0016020membrane IEA--
    GO:0035869ciliary transition zone ISS--
    GO:0036038TCTN-B9D complex ISS--

    B9D1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for B9D1
    Interactions:

        Search GeneGlobe Interaction Network for B9D1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    Selected Interacting proteins for B9D1 (Q9UPM93 ENSP000002614994) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EXOSC10Q017803, ENSP000003661354I2D: score=3 STRING: ENSP00000366135
    MRPS35P826733I2D: score=5 
    PAHP004393I2D: score=5 
    B9D2ENSP000002435784STRING: ENSP00000243578
    CEP290ENSP000003080214STRING: ENSP00000308021
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001701in utero embryonic development IEA--
    GO:0007224smoothened signaling pathway ISS--
    GO:0032880regulation of protein localization IEA--
    GO:0035051cardiocyte differentiation IEA--
    GO:0042384cilium assembly ISS--

    B9D1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for B9D1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for B9D1 gene (3 alternative transcripts): 
    NM_001243473.1  NM_001243475.1  NM_015681.3  

    Unigene Cluster for B9D1:

    B9 protein domain 1
    Hs.462445  [show with all ESTs]
    Unigene Representative Sequence: AK293815
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000575403(uc010cqm.1) ENST00000461069 ENST00000395615 ENST00000261499(uc002gvk.4)
    ENST00000477478(uc010vyr.2 uc010vys.2) ENST00000395616 ENST00000575478
    ENST00000268841(uc010cqn.2) ENST00000440841 ENST00000477683 ENST00000574508
    ENST00000582857 ENST00000487415 ENST00000468679 ENST00000476298
    miRNA
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    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Predesigned siRNA for gene silencing in human, mouse, rat B9D1
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    GenScript: all cDNA clones in your preferred vector: B9D1 (NM_015681)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for B9D1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat B9D1
    Primer
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    OriGene qPCR primer pairs and template standards for B9D1
    OriGene qSTAR qPCR primer pairs in human, mouse for B9D1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat B9D1
      QuantiTect SYBR Green Assays in human, mouse, rat B9D1
      QuantiFast Probe-based Assays in human, mouse, rat B9D1

    Additional mRNA sequence: 

    AB030506.1 AK293815.1 AK297782.1 AK309320.1 BC002944.2 

    9 DOTS entries:

    DT.440966  DT.100752236  DT.86842265  DT.95266441  DT.92420107  DT.91967891  DT.97801922  DT.95266450 
    DT.95266451 

    Selected AceView cDNA sequences (see all 84):

    CD676260 BQ012937 CN479141 CK819721 BE745789 CA776227 BU684397 AA243643 
    BM129815 BC002944 CR606056 BQ422055 BM976857 AW292166 AA256668 BU171805 
    AB030506 AA256667 BX389591 BI825552 BX507706 AI300844 CA389709 AI818169 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for B9D1 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9
    SP1:                                                        -     -           -                           
    SP2:                                                        -     -           -     -                     
    SP3:                                                        -                                             
    SP4:                                                        -     -                                       
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for B9D1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    B9D1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGAAACTGG
    B9D1 Expression
    About this image

    B9D1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    B9D1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.462445
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B9D1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for B9D1 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia B9d11 , 5 B9 protein domain 11, 5 87.91(n)1
    94.61(a)1
      11 (37.96 cM)5
    270781  NM_013717.21  NP_038745.11 
     615051445 
    chicken
    (Gallus gallus)
    Aves B9D11 B9 protein domain 1 74.21(n)
    80.53(a)
      416525  XM_004945217.1  XP_004945274.1 
    lizard
    (Anolis carolinensis)
    Reptilia B9D16
    B9 protein domain 1
    68(a)
    1 ↔ 1
    GL343618.1(403900-407663)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.234942 Xenopus laevis transcribed sequence with moderate similarity more 77.74(n)    BJ032226.1 
    zebrafish
    (Danio rerio)
    Actinopterygii b9d11 B9 protein domain 1 73.23(n)
    81.91(a)
      554150  NM_001024373.1  NP_001019544.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG148701 CG14870 49.27(n)
    35.71(a)
      41888  NM_142213.2  NP_650470.1 
    worm
    (Caenorhabditis elegans)
    Secernentea mksr-11 mksr-1 43.78(n)
    29.52(a)
      186954  NM_075802.1  NP_508203.1 


    ENSEMBL Gene Tree for B9D1 (if available)
    TreeFam Gene Tree for B9D1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for B9D1 gene
    B9D22  

    B9D1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for B9D1 (see all 695)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1156677011,2
    C,F--19228960(+) GGTGGC/TTTGCT 1 -- ds50011Minor allele frequency- T:0.09WA 118
    rs747250001,2
    C,F--19229113(+) GAGGCG/AGCTGG 1 -- ds50011Minor allele frequency- A:0.01NA 120
    rs800782751,2
    C--19229120(+) CTGGGA/GGACCC 1 -- ds50010--------
    rs1437528171,2
    --19229295(+) TGCCCA/GTTCAG 1 -- ut310--------
    rs1901870921,2
    --19229344(+) TCTTGC/GTTACG 1 -- ut310--------
    rs116527121,2
    C,F,H--19229388(+) CCCGCA/GGAAGT 1 -- ut3124Minor allele frequency- G:0.06NS EA NA WA CSA 2140
    rs787979421,2
    C,F--19229413(+) AGTGAC/ATCAGG 1 -- ut311Minor allele frequency- A:0.14EA 120
    rs739800091,2
    C,F--19229478(+) GGTGGC/GTATGA 1 -- spa12Minor allele frequency- G:0.10WA 120
    rs728368021,2
    C,F--19229511(+) AGCATA/GGATTT 1 -- int12Minor allele frequency- G:0.08NA EA 240
    rs1468507091,2
    --19229531(+) AGGCCA/TGGAAT 1 -- int10--------

    HapMap Linkage Disequilibrium report for B9D1 (19240867 - 19281495 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for B9D1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv907864CNV Loss21882294
    nsv833393CNV Gain+Loss17160897

    Human Gene Mutation Database (HGMD): B9D1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing B9D1
    DNA2.0 Custom Variant and Variant Library Synthesis for B9D1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614144   
    OMIM disorders: 614209  
    UniProtKB/Swiss-Prot: B9D1_HUMAN, Q9UPM9
  • Meckel syndrome 9 (MKS9) [MIM:614209]: A disorder characterized by a combination of renal cysts and
    variably associated features including developmental anomalies of the central nervous system (typically
    encephalocele), hepatic ductal dysplasia and cysts, and polydactyly. Note=The disease is caused by mutations
    affecting the gene represented in this entry

  • 15 diseases for B9D1:    
    About MalaCards
    b9d1-related meckel syndrome    meckel syndrome 9    meckel syndrome 1    meckel syndrome
    smith magenis syndrome    encephalocele    encephaloceles    cystic kidney
    nephronophthisis    polydactyly    endotheliitis    multiple myeloma
    malaria    myeloma    hepatitis

    3 diseases from the University of Copenhagen DISEASES database for B9D1:
    Nephronophthisis     Cystic kidney     Polydactyly

    B9D1 for disorders           About GeneDecksing


    Export disorders for B9D1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for B9D1 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with B9D1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. B9D1 is revealed as a novel Meckel syndrome (MKS) gene by targeted exon-enriched next-generation sequencing and deletion analysis. (PubMed id 21493627)1, 2, 3 Hopp K.... Harris P.C. (Hum. Mol. Genet. 2011)
    2. Functional interactions between the ciliopathy-associated Meckel syndrome 1 (MKS1) protein and two novel MKS1-related (MKSR) proteins. (PubMed id 19208769)1, 2 Bialas N.J.... Leroux M.R. (J. Cell Sci. 2009)
    3. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    4. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    8. Functional redundancy of the B9 proteins and nephrocystins in Caenorhabditis elegans ciliogenesis. (PubMed id 18337471)1 Williams C.L....Yoder B.K. (Mol. Biol. Cell 2008)
    9. A protein interaction framework for human mRNA degradation. (PubMed id 15231747)1 Lehner B. and Sanderson C.M. (Genome Res. 2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 27077 HGNC: 24123 AceView: EPPB9 Ensembl:ENSG00000108641 euGenes: HUgn27077
    ECgene: B9D1 H-InvDB: B9D1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for B9D1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for B9D1 gene:
    Search GeneIP for patents involving B9D1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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