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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

B4GALT6 Gene

protein-coding GIFtS: 54
GCID: GC18M029226

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide...

Explore 13 diseases affiliated with
B4GALT6 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase, Polypeptide 6¹ ²		Beta-1,4-Galactosyltransferase 6²
Beta4GalT-VI¹		Beta4Gal-T6³
Beta-1,4-GalTase 6² ³		UDP-Gal:Glucosylceramide Beta-1,4-Galactosyltransferase²
UDP-Gal:Beta-GlcNAc Beta-1,4-Galactosyltransferase 6² ³		Beta4Gal-T6³
UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,4-Galactosyltransferase 6² ³		EC 2.4.1.-³
B4Gal-T6²		B4Gal-T6²

External Ids:	HGNC: 929¹	Entrez Gene: 9331²	Ensembl: ENSG00000118276⁷	OMIM: 604017⁵	UniProtKB: Q9UBX8³

Export aliases for B4GALT6 gene to outside databases

Previous GC identifers: GC18M029022 GC18M027455 GC18M027457 GC18M026059

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for B4GALT6:

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound

glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose

in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the

biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an

N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains

uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1

and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene

is a lactosylceramide synthase important for glycolipid biosynthesis. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: B4GT6_HUMAN, Q9UBX8

Function: Required for the biosynthesis of glycosphingolipids

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000018.9 NC_018929.1 NT_010966.14

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the B4GALT6 gene promoter:
AhR POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) CUTL1 POU3F2 E47 RORalpha1 POU2F1 POU2F1a HFH-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): B4GALT6 promoter sequence

Search SABiosciences Chromatin IP Primers for B4GALT6

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B4GALT6

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q11 Ensembl cytogenetic band: 18q12.1 HGNC cytogenetic band: 18q11

B4GALT6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B4GALT6 gene location

GeneLoc information about chromosome 18 GeneLoc Exon Structure

GeneLoc location for GC18M029226: view genomic region (about GC identifiers)

Start:	29,202,209 bp from pter	End:	29,265,799 bp from pter
Size:	63,591 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: B4GT6_HUMAN, Q9UBX8 (See protein sequence)

Recommended Name: Beta-1,4-galactosyltransferase 6

Size: 382 amino acids; 44914 Da

Cofactor: Manganese or magnesium

Subcellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae

of Golgi stack

Secondary accessions: O60514

Explore the universe of human proteins at neXtProt for B4GALT6: NX_Q9UBX8

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9UBX8

B4GALT6 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_004766.2

ENSEMBL proteins:

ENSP00000306459 ENSP00000237019 ENSP00000372613 ENSP00000463961

Reactome Protein details: Q9UBX8
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Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	TAS	--
GO:0016021	integral to membrane	IEA	--
GO:0032580	Golgi cisterna membrane	IEA	--

B4GALT6 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

B4GALT6 for domains About GeneDecksing

1 InterPro domain/family:

IPR003859 Galactosyl_T_2_met

Graphical View of Domain Structure for InterPro Entry Q9UBX8

ProtoNet protein and cluster: Q9UBX8

1 Blocks protein family: IPB003859 Metazoa galactosyltransferase

UniProtKB/Swiss-Prot: B4GT6_HUMAN, Q9UBX8

Similarity: Belongs to the glycosyltransferase 7 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: B4GT6_HUMAN, Q9UBX8

Function: Required for the biosynthesis of glycosphingolipids

Catalytic activity: UDP-galactose + glucosylceramide = UDP + lactosylceramide

Catalytic activity: UDP-alpha-D-galactose + beta-D-glucosyl-(1<->1)-ceramide = UDP +

beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

Enzyme regulation: Inhibited by EDTA (By similarity)

Biophysicochemical properties: Kinetic parameters: KM=3 uM for glucosylceramide; KM=0.5 uM for UDP-galactose; Vmax=0.06

nmol/h/mg enzyme toward glucosylceramide; Vmax=86 nmol/h/mg enzyme toward UDP-galactose;

Genatlas biochemistry entry for B4GALT6:

UDP galactose

Enzyme Number (IUBMB): EC 2.4.1.-¹

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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B4GALT6

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008378	galactosyltransferase activity	TAS	9597550
GO:0008489	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	IEA	--
GO:0016757	transferase activity, transferring glycosyl groups	--	--
GO:0046872	metal ion binding	IEA	--

B4GALT6 for ontologies About GeneDecksing

Animal Models:
1 MGI mutant phenotype (inferred from 1 allele) (MGI details for B4galt6):

normal

B4GALT6 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

MPS IIIC - Sanfilippo syndrome C

8/14 pathways (see all 14)
MPS IIIC - Sanfilippo syndrome C	1.00	MPS IIIA - Sanfilippo syndrome A	1.00
MPS I - Hurler syndrome	1.00	MPS IIID - Sanfilippo syndrome D	1.00
Mucopolysaccharidoses	1.00	MPS IX - Natowicz syndrome	1.00
MPS IV - Morquio syndrome A	1.00	MPS II - Hunter syndrome	1.00

N-glycan antennae elongation in the medial/trans-Golgi

	N-glycan antennae elongation in the medial/trans-Golgi	1.00			Transport to the Golgi and subsequent modification	0.56
	N-Glycan antennae elongation	0.75

Asparagine N-linked glycosylation

	Asparagine N-linked glycosylation	1.00			Metabolism of proteins	0.15
	Post-translational protein modification	0.44

Keratan sulfate biosynthesis

Keratan sulfate biosynthesis

1.00

Keratan sulfate/keratin metabolism

0.84

Metabolism

Metabolism

1.00

Metabolic pathways

0.38

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for B4GALT6

Sperm Motility

5/25 Reactome Pathways for B4GALT6 (see all 25)

	MPS VI - Maroteaux-Lamy syndrome
	Metabolism
	Disease
	Keratan sulfate/keratin metabolism
	Transport to the Golgi and subsequent modification

2 Kegg Pathways (Kegg details for B4GALT6):

	Sphingolipid metabolism
	Metabolic pathways

UniProtKB/Swiss-Prot: B4GT6_HUMAN, Q9UBX8

Pathway: Protein modification; protein glycosylation

B4GALT6 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for B4GALT6

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

5/8 Interacting proteins for B4GALT6 (ENSP00000306459⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 8)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GBA	ENSP00000314508⁴	STRING: ENSP00000314508
UGCG	ENSP00000363397⁴	STRING: ENSP00000363397
A4GALT	ENSP00000249005⁴	STRING: ENSP00000249005
B3GNT5	ENSP00000316173⁴	STRING: ENSP00000316173
B4GALNT1	ENSP00000341562⁴	STRING: ENSP00000341562

About this table

Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005975	carbohydrate metabolic process	TAS	--
GO:0018146	keratan sulfate biosynthetic process	TAS	--
GO:0018279	protein N-linked glycosylation via asparagine	TAS	--
GO:0030203	glycosaminoglycan metabolic process	TAS	--
GO:0042339	keratan sulfate metabolic process	TAS	--

B4GALT6 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

B4GALT6 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for B4GALT6

10/45 HMDB Compounds for B4GALT6 (see all 45) About this table

Compound	Synonyms	CAS #	PubMed Ids
3-O-Sulfogalactosylceramide (d18:1/12:0)	Sulfatide (d18:1/12:0) (see all 13)	852100-88-0	--
3-O-Sulfogalactosylceramide (d18:1/14:0)	Sulfatide (d18:1/14:0) (see all 13)	--	--
3-O-Sulfogalactosylceramide (d18:1/16:0)	Sulfatide (d18:1/16:0) (see all 13)	862509-48-6	--
3-O-Sulfogalactosylceramide (d18:1/18:0)	Sulfatide (d18:1/18:0) (see all 13)	244215-65-4	--
3-O-Sulfogalactosylceramide (d18:1/18:1(9Z))	Sulfatide (d18:1/18:1(9Z)) (see all 13)	--	--
3-O-Sulfogalactosylceramide (d18:1/20:0)	Sulfatide (d18:1/20:0) (see all 13)	265096-81-9	--
3-O-Sulfogalactosylceramide (d18:1/22:0)	Sulfatide (d18:1/22:0) (see all 13)	265096-83-1	--
3-O-Sulfogalactosylceramide (d18:1/24:0)	Sulfatide (d18:1/24:0) (see all 16)	151122-71-3	--
3-O-Sulfogalactosylceramide (d18:1/24:1(15Z))	Sulfatide (d18:1/24:1(15Z)) (see all 13)	151057-28-2	--
3-O-Sulfogalactosylceramide (d18:1/26:1(17Z))	Sulfatide (d18:1/26:1(17Z)) (see all 13)	928346-40-1	--

7 Novoseek chemical compound relationships for B4GALT6 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
laccer	96.7	36	19219548 (4), 8175761 (3), 18393821 (3), 16151023 (2) (see all 15)
lactosylceramide	96.4	29	10320813 (4), 8175761 (2), 15936020 (2), 8808768 (1) (see all 19)
glucosylceramide	92.4	18	7592537 (1), 8808768 (1), 11740154 (1), 19411660 (1) (see all 14)
glycosphingolipid	86	2	15611100 (1), 8175761 (1)
shiga toxin	81.5	3	15633106 (1)
ceramide	76.6	5	11740154 (1), 8781979 (1), 12232838 (1), 16100442 (1) (see all 5)
galactose	40.6	2	15633106 (1), 10320813 (1)

Search CenterWatch for drugs/clinical trials and news about B4GALT6 / B4GT6

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for B4GALT6 gene:

NM_004775.3

Unigene Cluster for B4GALT6:

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6

Hs.591063 [show with all ESTs]

Unigene Representative Sequence: NM_004775

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000578114(uc002kwy.4 uc002kwz.4 uc010dma.3 uc010dmb.3)

ENST00000306851 ENST00000237019 ENST00000383131 ENST00000579372

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Additional cDNA sequence:

AB024742.2 AB209194.1 AF038664.1 AF069054.1 AF097159.1 AK314860.1 BC069620.1 BC069642.1

BC074835.2 BC074884.2

5 DOTS entries:

DT.75147548 DT.100672206 DT.95174538 DT.92418574 DT.95345331

24/49 AceView cDNA sequences (see all 49):

BC074884 BE218836 F07007 AB024742 Z40117 BC074835 BF001183 AA599568

BC069620 BE222493 AF097159 BE241586 CD654869 AI190692 AI915338 AL043156

AL601725 AI694586 NM_004775 BF378154 BM801139 AW451997 BC069642 AW452091

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for B4GALT6 About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3a	·	3b	^	4	^	5	^	6	^	7	^	8	^	9a	·	9b	·	9c
SP1:									-
SP2:							-		-
SP3:									-						-
SP4:													-		-

ECgene alternative splicing isoforms for B4GALT6

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

B4GALT6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

B4GALT6 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

4 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Gut Tube

Midgut

Midgut Endoderm Cells

Endoderm

Neural Tube

Spinal Neural Tube Cells

Neural Ectoderm

Gut Tube

Midgut

Gut Tube

Spinal Cord

Presumptive Spinal Cord

Spinal Cord

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See B4GALT6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for B4GALT6

SOURCE GeneReport for Unigene cluster: Hs.591063

UniProtKB/Swiss-Prot: B4GT6_HUMAN, Q9UBX8

Tissue specificity: High expression in brain and adrenal gland, lower in liver, lung, colon and peripheral white blood

cells

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B4GALT6

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for B4GALT6 gene from 6/21 species (see all 21) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	B4GALT6¹	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, more	82.97(n) 91.03(a)		421092 NM_001031016.1 NP_001026187.1
lizard (Anolis carolinensis)	Reptilia	B4GALT6⁶	--	80(a)	1 ↔ 1	GL343207.1(3762587-3770698)
African clawed frog (Xenopus laevis)	Amphibia	BC060428.1²	--	78.38(n)		BC060428.1
zebrafish (Danio rerio)	Actinopterygii	zgc55730²	similar to UDP-GalbetaGlcNAc beta 1,4- galactosyltransferase, more	77.91(n)		393912 BC046890.1
fruit fly (Drosophila melanogaster)	Insecta	CG14517³	UDP-galactose-glucosylceramide beta-1,4-galactosyltransferase	38(a) (best of 2)		98F5 --
worm (Caenorhabditis elegans)	Secernentea	W02B12.11³	n-acetyllactosamine synthase	41(a)		II(11473999-11475645) --

ENSEMBL Gene Tree for B4GALT6 (if available)
TreeFam Gene Tree for B4GALT6 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for B4GALT6 gene

B4GALT2² B4GALT5² B4GALT7² B4GALT4² B4GALT1² B4GALT3²

5 SIMAP similar genes for B4GALT6 using alignment to 5 protein entries: B4GT6_HUMAN (see all proteins):

B4GALT5 B4GALT4 B4GALT1 B4GALT3 B4GALT2

B4GALT6 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
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SNP ID	Valid	Clinical significance	Chr 18 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs186777897^1,2		--	29201854(+)	`TCATCC/GATACC`	1	--	ds500¹		0	--	--	--	--
rs77563974^1,2		--	29202039(+)	`AAGGTC/GATCTC`	1	--	ds500¹		0	--	--	--	--
rs150233857^1,2		--	29202049(+)	`CCACCC/TGTATT`	1	--	ds500¹		0	--	--	--	--
rs79242721^1,2	F,	--	29202210(+)	`AAAGTC/ATTTAG`	1	--	ut3¹		1		WA	118
rs138954612^1,2		--	29202333(+)	`AGAAGA/CCTTTC`	1	--	ut3¹		0	--	--	--	--
rs191909751^1,2		--	29202395(+)	`TACTAC/TAACCA`	1	--	ut3¹		0	--	--	--	--
rs149422375^1,2		--	29202453(+)	`TACAAC/TAGTAT`	1	--	ut3¹		0	--	--	--	--
rs183304335^1,2		--	29202535(+)	`CACTTA/GTAGGA`	1	--	ut3¹		0	--	--	--	--
rs116203117^1,2	F,	--	29202618(+)	`AAAGGG/ATATAT`	1	--	ut3¹		1		WA	118
rs187794863^1,2		--	29202756(+)	`AGAATA/TAACTA`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for B4GALT6 (29202209 - 29265799 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for B4GALT6
1 CNV: 102626
1 Indel: 58824

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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B4GALT6 for disorders           About GeneDecksing

OMIM gene information: 604017    OMIM disorders: --

13 diseases for B4GALT6:    About MalaCards

amyotrophic lateral sclerosis congenital disorder of glycosylation lateral sclerosis polycystic kidney disease

kidney disease prostate carcinoma in situ ovarian carcinoma prostate carcinoma

carcinoma schizophrenia immunodeficiency melanoma

prostatitis

Export disorders for B4GALT6 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for B4GALT6 gene, integrated from 9 sources (see all 40):
(articles sorted by number of sources associating them with B4GALT6)

Utopia: connect your pdf to the dynamic
world of online information

The expanding beta 4-galactosyltransferase gene family: messages from the databanks. (PubMed id 9597550)^{1, 2, 3} Lo N.-W.... Shaper N.L. (1998)
cDNA cloning and expression of human lactosylceramide synthase. (PubMed id 10320813)^{1, 2, 9} Takizawa M.... Matsuo N. (1999)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Molecular cloning, genomic organization, and mapping of beta 4GalT- VIb, a brain abundant member of beta 4-galactosyltransferase gene family, to human chromosome 18q12.1. (PubMed id 12180132)^{1, 3} Fan Y....Zhao S. (2002)
Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. (PubMed id 10580128)^{1, 2} Amado M.... Clausen H. (1999)
Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. (PubMed id 19451621)¹ Landers J.E....Brown R.H. (2009)
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)¹ Gevaert K.... Vandekerckhove J. (2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Purification of uridine diphosphate-galactose:glucosyl ceramide, beta 1-4 galactosyltransferase from human kidney. (PubMed id 1551920)² Chatterjee S....Khurana S. (1992)
Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1. (PubMed id 2187500)¹ Kalyanaraman V.S....Sarngadharan M.G. (1990)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 9331	HGNC: 929	AceView: B4GALT6	Ensembl:ENSG00000118276	euGenes: HUgn9331
ECgene: B4GALT6	Kegg: 9331	H-InvDB: B4GALT6

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for B4GALT6	Pharmacogenomics, SNPs, Pathways
GGDB	http://riodb.ibase.aist.go.jp/rcmg/ggdb/
Functional Glycomics Gateway - GTase	http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_441

Intellectual Property for B4GALT6 gene
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Patent Information for B4GALT6 gene:
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GeneCards and IP:
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