Aliases for B4GALT5 Gene
- UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase, Polypeptide 5 2 3
- UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,4-Galactosyltransferase 5 3 4
- UDP-Gal:Beta-GlcNAc Beta-1,4-Galactosyltransferase 5 3 4
- Beta-1,4-GalTase 5 3 4
- Beta-1,4-GalT II 3 4
- Beta4-GalT IV 2 3
- Beta4Gal-T5 3 4
- B4Gal-T5 3 4
- UDP-Gal:BetaGlcNAc Beta 1,4-Galactosyltransferase, Polypeptide 5 3
External Ids for B4GALT5 Gene
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The function of the enzyme encoded by this gene is not clear. This gene was previously designated as B4GALT4 but was renamed to B4GALT5. In the literature it is also referred to as beta4GalT2. [provided by RefSeq, Jul 2008]
GeneCards Summary for B4GALT5 Gene
B4GALT5 (UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase, Polypeptide 5) is a Protein Coding gene. Diseases associated with B4GALT5 include nasopharynx carcinoma. Among its related pathways are Disease and Metabolism. GO annotations related to this gene include galactosyltransferase activity. An important paralog of this gene is B4GALT7.
UniProtKB/Swiss-Prot for B4GALT5 Gene
Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.