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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

B4GALT4 Gene

protein-coding GIFtS: 57
GCID: GC03M118930

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide...

Explore 2 diseases affiliated with
B4GALT4 via

MalaCards

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Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase, Polypeptide 4¹ ²		Beta-1,4-Galactosyltransferase 4²
Beta4Gal-T4³		Beta-N-Acetylglucosaminyl-Glycolipid Beta-1,4-Galactosyltransferase 4²
Beta-1,4-GalTase 4² ³		UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase 4²
UDP-Gal:Beta-GlcNAc Beta-1,4-Galactosyltransferase 4² ³		Beta4Gal-T4³
UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,4-Galactosyltransferase 4² ³		EC 2.4.1.-³
B4Gal-T4²		B4Gal-T4²

External Ids:	HGNC: 927¹	Entrez Gene: 8702²	Ensembl: ENSG00000121578⁷	OMIM: 604015⁵	UniProtKB: O60513³

Export aliases for B4GALT4 gene to outside databases

Previous GC identifers: GC03M115619 GC03M118559 GC03M120211 GC03M120251 GC03M120413 GC03M116306

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for B4GALT4:

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound

glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose

in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the

biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an

N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains

uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1

and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene

appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been

found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: B4GT4_HUMAN, O60513

Function: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the

carbohydrate moieties of glycolipids

Gene Wiki entry for B4GALT4

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000003.11 NC_018914.1 NT_005612.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the B4GALT4 gene promoter:
GATA-3 Nkx2-5 GATA-2 GATA-1 Arnt
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): B4GALT4 promoter sequence

Search SABiosciences Chromatin IP Primers for B4GALT4

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B4GALT4

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q13.3 Ensembl cytogenetic band: 3q13.32 HGNC cytogenetic band: 3q13.3

B4GALT4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B4GALT4 gene location

GeneLoc information about chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03M118930: view genomic region (about GC identifiers)

Start:	118,930,579 bp from pter	End:	118,959,950 bp from pter
Size:	29,372 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: B4GT4_HUMAN, O60513 (See protein sequence)

Recommended Name: Beta-1,4-galactosyltransferase 4

Size: 344 amino acids; 40041 Da

Cofactor: Manganese (By similarity)

Subcellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae

of Golgi stack

Secondary accessions: Q68D68 Q9BSW3 Q9C078

Explore the universe of human proteins at neXtProt for B4GALT4: NX_O60513

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O60513

B4GALT4 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_003769.1 NP_997708.1

ENSEMBL proteins:

ENSP00000420161 ENSP00000417226 ENSP00000417527 ENSP00000352144 ENSP00000377360

ENSP00000420665 ENSP00000419919 ENSP00000417188 ENSP00000417958 ENSP00000420535

ENSP00000418436 ENSP00000419916 ENSP00000419275 ENSP00000418278

Reactome Protein details: O60513
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Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	TAS	--
GO:0016021	integral to membrane	IEA	--
GO:0032580	Golgi cisterna membrane	IEA	--

B4GALT4 for ontologies About GeneDecksing

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	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

B4GALT4 for domains About GeneDecksing

1 InterPro domain/family:

IPR003859 Galactosyl_T_2_met

Graphical View of Domain Structure for InterPro Entry O60513

ProtoNet protein and cluster: O60513

1 Blocks protein family: IPB003859 Metazoa galactosyltransferase

UniProtKB/Swiss-Prot: B4GT4_HUMAN, O60513

Similarity: Belongs to the glycosyltransferase 7 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: B4GT4_HUMAN, O60513

Function: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the

carbohydrate moieties of glycolipids

Catalytic activity: UDP-alpha-D-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine

Catalytic activity: UDP-alpha-D-galactose +

N-acetyl-beta-D-galactosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP +

beta-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-beta-D-galactosyl-(1->4)--D-glucosyl-(1<->1)-ceramide

Biophysicochemical properties: Kinetic parameters: KM=238 uM for GlcNAc-B-S-pNP;

Genatlas biochemistry entry for B4GALT4:

UDP galactose

Enzyme Number (IUBMB): EC 2.4.1.-¹

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B4GALT4

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003945	N-acetyllactosamine synthase activity	IEA	--
GO:0008378	galactosyltransferase activity	TAS	9792633
GO:0016757	transferase activity, transferring glycosyl groups	--	--
GO:0046872	metal ion binding	IEA	--

B4GALT4 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for B4GALT4:

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

MPS IIIC - Sanfilippo syndrome C

8/14 pathways (see all 14)
MPS IIIC - Sanfilippo syndrome C	1.00	MPS IIIA - Sanfilippo syndrome A	1.00
MPS I - Hurler syndrome	1.00	MPS IIID - Sanfilippo syndrome D	1.00
Mucopolysaccharidoses	1.00	MPS IX - Natowicz syndrome	1.00
MPS IV - Morquio syndrome A	1.00	MPS II - Hunter syndrome	1.00

N-glycan antennae elongation in the medial/trans-Golgi

	N-glycan antennae elongation in the medial/trans-Golgi	1.00			Transport to the Golgi and subsequent modification	0.56
	N-Glycan antennae elongation	0.75

Asparagine N-linked glycosylation

	Asparagine N-linked glycosylation	1.00			Metabolism of proteins	0.15
	Post-translational protein modification	0.44

Keratan sulfate biosynthesis

	Keratan sulfate biosynthesis	1.00			Glycosaminoglycan biosynthesis - keratan sulfate	0.45
	Keratan sulfate/keratin metabolism	0.84

Metabolism

Metabolism

1.00

Metabolic pathways

0.38

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for B4GALT4

Sperm Motility

5/24 Reactome Pathways for B4GALT4 (see all 24)

	MPS VI - Maroteaux-Lamy syndrome
	Metabolism
	Disease
	Keratan sulfate/keratin metabolism
	Transport to the Golgi and subsequent modification

3 Kegg Pathways (Kegg details for B4GALT4):

	Glycosaminoglycan biosynthesis - keratan sulfate
	Glycosphingolipid biosynthesis - lacto and neolacto series
	Metabolic pathways

UniProtKB/Swiss-Prot: B4GT4_HUMAN, O60513

Pathway: Protein modification; protein glycosylation

B4GALT4 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for B4GALT4

STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

5/17 Interacting proteins for B4GALT4 (ENSP00000352144⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 17)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
B3GNT2	ENSP00000305595⁴	STRING: ENSP00000305595
FUT2	ENSP00000375748⁴	STRING: ENSP00000375748
B3GALT1	ENSP00000303740⁴	STRING: ENSP00000303740
B3GALT2	ENSP00000356404⁴	STRING: ENSP00000356404
B3GALT5	ENSP00000343318⁴	STRING: ENSP00000343318

About this table

Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005975	carbohydrate metabolic process	TAS	--
GO:0006643	membrane lipid metabolic process	TAS	9792633
GO:0018146	keratan sulfate biosynthetic process	TAS	--
GO:0018279	protein N-linked glycosylation via asparagine	TAS	--
GO:0030203	glycosaminoglycan metabolic process	TAS	--

B4GALT4 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

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Browse Tocris compounds for B4GALT4

5 HMDB Compounds for B4GALT4 About this table

Compound	Synonyms	CAS #	PubMed Ids
Manganese	manganese	7439-96-5	--
N-Acetyl-D-glucosamine	2-(acetylamino)-2-deoxyhexose (see all 9)	7512-17-6	--
N-Acetyllactosamine	D-galactopyranosyl (see all 8)	32181-59-2	--
Uridine 5'-diphosphate	5'-UDP (see all 9)	58-98-0	--
Uridine diphosphategalactose	GDU (see all 39)	2956-16-3	--

1 DrugBank Compound for B4GALT4 About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
N-Acetyl-D-glucosamine	2-Acetamido-2-deoxy-D-glucose (see all 4)	7512-17-6	target	--	11948877 17139284 17016423

Search CenterWatch for drugs/clinical trials and news about B4GALT4 / B4GT4

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for B4GALT4 gene (2 alternative transcripts):

NM_003778.3 NM_212543.1

Unigene Cluster for B4GALT4:

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4

Hs.13225 [show with all ESTs]

Unigene Representative Sequence: BC062618

18/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):

ENST00000483209(uc003ecg.3) ENST00000467604(uc003ece.1) ENST00000471675

ENST00000359213(uc003ech.3 uc011biy.1) ENST00000393765(uc003eci.3)

ENST00000480814 ENST00000460321 ENST00000491906 ENST00000475803 ENST00000479150

ENST00000470111 ENST00000493932 ENST00000473887 ENST00000459778 ENST00000459820

ENST00000460395 ENST00000472471 ENST00000484595

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Additional cDNA sequence:

AB024436.1 AF020920.1 AF022367.1 AF038662.1 AK001006.1 AK301688.1 AK314425.1 AY359008.1

BC004523.2 BC062618.1 CR749555.1

20 DOTS entries:

DT.100781999 DT.91720381 DT.99944653 DT.453314 DT.120875620 DT.120875594 DT.99985352 DT.120875597

DT.91720382 DT.120875588 DT.120875612 DT.120875599 DT.120875605 DT.120875619 DT.120875621 DT.120875583

DT.120875593 DT.120875596 DT.120875600 DT.100692235

24/276 AceView cDNA sequences (see all 276):

AA046963 BU617040 CR626075 AI801723 AA446926 BP335987 AL544819 BP337750

AW140052 AI597740 BX359105 AA031686 BP363762 AK001006 AI056532 BP373064

BP336769 BP337521 BP363037 AB024436 BP335423 BI755758 BF814627 BP336934

GeneLoc Exon Structure

5/17 Alternative Splicing Database (ASD) splice patterns (SP) for B4GALT4 (see all 17) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	^	2a	·	2b	^	3a	·	3b	^	4	^	5	^	6	^	7	^	8	^	9	^	10a	·	10b	·	10c	·	10d	·	10e	·	10f	·	10g	·	10h	^	11a	·	11b	·	11c	^
SP1:																	-		-				-		-		-		-
SP2:																							-				-		-
SP3:																							-		-		-		-
SP4:									-		-		-				-		-				-				-		-
SP5:									-		-		-		-		-		-				-				-		-

ExUns:	12a	·	12b	^	13	^	14	^	15a	·	15b	^	16
SP1:					-						-
SP2:					-						-
SP3:					-
SP4:
SP5:

ECgene alternative splicing isoforms for B4GALT4

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

B4GALT4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGGTTAAAT

About this image

B4GALT4 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Cartilage-like cells (Differentiation of s...)

Cartilage

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See B4GALT4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for B4GALT4

SOURCE GeneReport for Unigene cluster: Hs.13225

UniProtKB/Swiss-Prot: B4GT4_HUMAN, O60513

Tissue specificity: High expression in heart, placenta, kidney and pancreas; lower in brain, colon, lung, muscle,

ovary, testis and uterus

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for B4GALT4 gene from 6/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	B4GALT4¹	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, more	70.47(n) 71.47(a)		418341 XM_416563.2 XP_416563.1
lizard (Anolis carolinensis)	Reptilia	B4GALT4⁶	--	67(a)	1 ↔ 1	3(181298103-181314705)
African clawed frog (Xenopus laevis)	Amphibia	Xl.15219²	Xenopus laevis transcribed sequence with moderate similarity more	77.07(n)		BJ043501.1
zebrafish (Danio rerio)	Actinopterygii	57087003²	--	72.1(n)		57087003
fruit fly (Drosophila melanogaster)	Insecta	BcDNA:GH13356³	beta-N-acetylglucosaminyl-glycopeptide beta-1,4-galactosyltransferase	42(a) (best of 2)		50E6 --
worm (Caenorhabditis elegans)	Secernentea	Y73E7A.7³	--	44(a) (best of 2)		I(1621527-1626606) --

ENSEMBL Gene Tree for B4GALT4 (if available)
TreeFam Gene Tree for B4GALT4 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for B4GALT4 gene

B4GALT5² B4GALT2² B4GALT7² B4GALT1² B4GALT6² B4GALT3²

5 SIMAP similar genes for B4GALT4 using alignment to 11 protein entries: B4GT4_HUMAN (see all proteins):

B4GALT3 B4GALT2 B4GALT1 B4GALT5 B4GALT6

B4GALT4 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
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SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs72655949^1,2	C,F,	--	118930114(-)	`TGAAAC/TGTTTA`	2	--	ds500¹		2		NS WA	874
rs72655948^1,2	C,F,	--	118930145(-)	`GAATTT/GGAAAG`	2	--	ds500¹		2		NS WA	876
rs72655947^1,2	C,	--	118930273(-)	`TAACAA/-GAATG`	2	--	ds500¹		2		NS CSA	748
rs142285407^1,2		--	118930303(+)	`TCATAA/CAATAA`	2	--	ds500¹		0	--	--	--	--
rs6438503^1,2	C,F,A,H,	--	118930386(+)	`ATGGAC/TGGGCC`	2	--	ds500¹		31		EA NA NS WA CSA	3321
rs146776660^1,2		--	118930460(+)	`AAGGAA/CGGGAG`	2	--	ds500¹		0	--	--	--	--
rs12630690^1,2	C,F,H,	--	118930464(+)	`ACGGGA/TGACAG`	2	--	ds500¹		29		NA NS EA WA	3598
rs72655946^1,2	C,F,	--	118930482(-)	`CAAAGC/GCCTCC`	2	--	ds500¹		2		NS WA	864
rs35816234^1,2	C,F,	--	118930483(+)	`GAGGGC/TTTTGT`	2	--	ds500¹		6		NA NS WA EA	1108
rs72655945^1,2	C,F,	--	118930524(-)	`GTATCC/TATAAT`	2	--	ds500¹		1		NS	744

HapMap Linkage Disequilibrium report for B4GALT4 (118930579 - 118959950 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for B4GALT4
1 CNV: 63565

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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B4GALT4 for disorders           About GeneDecksing

OMIM gene information: 604015    OMIM disorders: --

2 diseases for B4GALT4:    About MalaCards

acne immunodeficiency

Export disorders for B4GALT4 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for B4GALT4 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with B4GALT4)

Utopia: connect your pdf to the dynamic
world of online information

The expanding beta 4-galactosyltransferase gene family: messages from the databanks. (PubMed id 9597550)^{1, 2, 3} Lo N.-W.... Shaper N.L. (1998)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Galactosylation of N-linked oligosaccharides by human beta-1,4- galactosyltransferases I, II, III, IV, V, and VI expressed in Sf-9 cells. (PubMed id 11588157)^{1, 2} Guo S.... Furukawa K. (2001)
Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. (PubMed id 10580128)^{1, 2} Amado M.... Clausen H. (1999)
Cloning of a novel member of the UDP-galactose:beta-N- acetylglucosamine beta1,4-galactosyltransferase family, beta4Gal-T4, involved in glycosphingolipid biosynthesis. (PubMed id 9792633)^{1, 2} Schwientek T....Clausen H. (1998)
Chemoenzymatic synthesis of biotinylated nucleotide sugars as substrates for glycosyltransferases. (PubMed id 11948877)^{7, 9} Bulter T....Elling L. (2001)
Comparison of HPLC/ESI-FTICR MS versus MALDI-TOF/TOF M S for glycopeptide analysis of a highly glycosylated HIV envelope glycoprotein. (PubMed id 18565761)¹ Irungu J....Desaire H. (2008)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)⁷ Imming P....Meyer A. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 8702	HGNC: 927	AceView: B4GALT4	Ensembl:ENSG00000121578	euGenes: HUgn8702
ECgene: B4GALT4	Kegg: 8702	H-InvDB: B4GALT4

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for B4GALT4	Pharmacogenomics, SNPs, Pathways
GGDB	http://riodb.ibase.aist.go.jp/rcmg/ggdb/
Functional Glycomics Gateway - GTase	http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_439

Intellectual Property for B4GALT4 gene
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Patent Information for B4GALT4 gene:
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