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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

B4GALT3 Gene

protein-coding GIFtS: 57
GCID: GC01M161141

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide...

Explore 7 diseases affiliated with
B4GALT3 via

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Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase, Polypeptide 3¹ ²		UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,4-Galactosyltransferase 3² ³
Beta4Gal-T3³		Beta-1,4-Galactosyltransferase 3²
Beta-1,4-GalTase 3² ³		Beta-N-Acetylglucosaminyl-Glycolipid Beta-1,4-Galactosyltransferase 3²
B4Gal-T3¹		Beta4Gal-T3³
UDP-Gal:Beta-GlcNAc Beta-1,4-Galactosyltransferase 3² ³		EC 2.4.1.-³

External Ids:	HGNC: 926¹	Entrez Gene: 8703²	Ensembl: ENSG00000158850⁷	OMIM: 604014⁵	UniProtKB: O60512³

Export aliases for B4GALT3 gene to outside databases

Previous GC identifers: GC01M158852 GC01M156873 GC01M157918 GC01M158357 GC01M157954 GC01M159407 GC01M132498

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for B4GALT3:

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound

glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose

in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the

biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an

N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains

uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1

and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that

may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains.

Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. (provided

by RefSeq, Dec 2010)

UniProtKB/Swiss-Prot: B4GT3_HUMAN, O60512

Function: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the

carbohydrate moieties of glycolipids

Gene Wiki entry for B4GALT3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_004487.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the B4GALT3 gene promoter:
Spz1 AP-1 MyoD HNF-4alpha2 NF-kappaB HNF-4alpha1 GATA-1 NF-kappaB1 Pax-4a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: B4GALT3 promoter sequence

Search SABiosciences Chromatin IP Primers for B4GALT3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B4GALT3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21-q23 Ensembl cytogenetic band: 1q23.3 HGNC cytogenetic band: 1q21-q23

B4GALT3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B4GALT3 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M161141: view genomic region (about GC identifiers)

Start:	161,141,100 bp from pter	End:	161,147,314 bp from pter
Size:	6,215 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: B4GT3_HUMAN, O60512 (See protein sequence)

Recommended Name: Beta-1,4-galactosyltransferase 3

Size: 393 amino acids; 43928 Da

Cofactor: Manganese (By similarity)

Subcellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae

of Golgi stack

Secondary accessions: D3DVG3 O60910 Q9BPZ4 Q9H8T2

Alternative splicing: 2 isoforms: O60512-1 O60512-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for B4GALT3: NX_O60512

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O60512

B4GALT3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001186802.1 NP_001186803.1 NP_003770.1

ENSEMBL proteins:

ENSP00000320965 ENSP00000356977

Reactome Protein details: O60512
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Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	TAS	--
GO:0005737	cytoplasm	IDA	--
GO:0005794	Golgi apparatus	IDA	--
GO:0016021	integral to membrane	IEA	--
GO:0032580	Golgi cisterna membrane	IEA	--

B4GALT3 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

B4GALT3 for domains About GeneDecksing

1 InterPro domain/family:

IPR003859 Galactosyl_T_2_met

Graphical View of Domain Structure for InterPro Entry O60512

ProtoNet protein and cluster: O60512

1 Blocks protein family: IPB003859 Metazoa galactosyltransferase

UniProtKB/Swiss-Prot: B4GT3_HUMAN, O60512

Similarity: Belongs to the glycosyltransferase 7 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: B4GT3_HUMAN, O60512

Function: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the

carbohydrate moieties of glycolipids

Catalytic activity: UDP-alpha-D-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP +

beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide

Catalytic activity: UDP-alpha-D-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine

Biophysicochemical properties: Kinetic parameters: KM=63 uM for GlcNAc-B-S-pNP;

Genatlas biochemistry entry for B4GALT3:

UDP galactose

Enzyme Number (IUBMB): EC 2.4.1.-¹

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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B4GALT3

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity	IEA	--
GO:0003945	N-acetyllactosamine synthase activity	IEA	--
GO:0008378	galactosyltransferase activity	TAS	9405390
GO:0046872	metal ion binding	IEA	--

B4GALT3 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for B4GALT3:

Increased G2M DNA content

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

MPS IIIC - Sanfilippo syndrome C

8/14 pathways (see all 14)
MPS IIIC - Sanfilippo syndrome C	1.00	MPS IIIA - Sanfilippo syndrome A	1.00
MPS I - Hurler syndrome	1.00	MPS IIID - Sanfilippo syndrome D	1.00
Mucopolysaccharidoses	1.00	MPS IX - Natowicz syndrome	1.00
MPS IV - Morquio syndrome A	1.00	MPS II - Hunter syndrome	1.00

Asparagine N-linked glycosylation

	Asparagine N-linked glycosylation	1.00			Post-translational protein modification	0.44
	N-Glycan biosynthesis	0.52			Metabolism of proteins	0.15

N-glycan antennae elongation in the medial/trans-Golgi

	N-glycan antennae elongation in the medial/trans-Golgi	1.00			Transport to the Golgi and subsequent modification	0.56
	N-Glycan antennae elongation	0.75

Keratan sulfate biosynthesis

	Keratan sulfate biosynthesis	1.00			Glycosaminoglycan biosynthesis - keratan sulfate	0.45
	Keratan sulfate/keratin metabolism	0.84

Metabolism

Metabolism

1.00

Metabolic pathways

0.38

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for B4GALT3

Sperm Motility

5/24 Reactome Pathways for B4GALT3 (see all 24)

	MPS VI - Maroteaux-Lamy syndrome
	Metabolism
	Disease
	Keratan sulfate/keratin metabolism
	Transport to the Golgi and subsequent modification

5 Kegg Pathways (Kegg details for B4GALT3):

	N-Glycan biosynthesis
	Other types of O-glycan biosynthesis
	Glycosaminoglycan biosynthesis - keratan sulfate
	Glycosphingolipid biosynthesis - lacto and neolacto series
	Metabolic pathways

UniProtKB/Swiss-Prot: B4GT3_HUMAN, O60512

Pathway: Protein modification; protein glycosylation

B4GALT3 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for B4GALT3

STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

5/24 Interacting proteins for B4GALT3 (O60512^{2, 3} ENSP00000320965⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 24)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ARL15	Q9NXU5²^,³	MINT-64611 I2D: score=5
SAT1	P21673²^,³	MINT-63557 I2D: score=5
SURF2	Q15527²^,³, ENSP00000361032⁴	MINT-63176 I2D: score=4 STRING: ENSP00000361032
B3GALT1	ENSP00000303740⁴	STRING: ENSP00000303740
B3GNT2	ENSP00000305595⁴	STRING: ENSP00000305595

About this table

Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005975	carbohydrate metabolic process	TAS	--
GO:0018146	keratan sulfate biosynthetic process	TAS	--
GO:0018279	protein N-linked glycosylation via asparagine	TAS	--
GO:0030203	glycosaminoglycan metabolic process	TAS	--
GO:0042339	keratan sulfate metabolic process	TAS	--

B4GALT3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

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Browse Tocris compounds for B4GALT3

5 HMDB Compounds for B4GALT3 About this table

Compound	Synonyms	CAS #	PubMed Ids
Manganese	manganese	7439-96-5	--
N-Acetyl-D-glucosamine	2-(acetylamino)-2-deoxyhexose (see all 9)	7512-17-6	--
N-Acetyllactosamine	D-galactopyranosyl (see all 8)	32181-59-2	--
Uridine 5'-diphosphate	5'-UDP (see all 9)	58-98-0	--
Uridine diphosphategalactose	GDU (see all 39)	2956-16-3	--

1 DrugBank Compound for B4GALT3 About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
N-Acetyl-D-glucosamine	2-Acetamido-2-deoxy-D-glucose (see all 4)	7512-17-6	target	--	17139284 17016423

Search CenterWatch for drugs/clinical trials and news about B4GALT3 / B4GT3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for B4GALT3 gene (3 alternative transcripts):

NM_001199873.1 NM_001199874.1 NM_003779.3

Unigene Cluster for B4GALT3:

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3

Hs.321231 [show with all ESTs]

Unigene Representative Sequence: NM_001199873

12 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000319769(uc001fyp.1 uc001fyr.2 uc001fyq.2) ENST00000470882(uc009wud.2)

ENST00000367998(uc001fys.2) ENST00000486938 ENST00000466504 ENST00000465740

ENST00000493164 ENST00000496313 ENST00000487004 ENST00000460415 ENST00000482288

ENST00000467863

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Additional cDNA sequence:

AB024435.1 AF038661.1 AK094384.1 AK291455.1 BC000276.1 BC006099.1 BC009985.2 Y12509.1

24/28 DOTS entries (see all 28):

DT.100844432 DT.100820316 DT.447372 DT.95367558 DT.95367553 DT.121391037 DT.95367546 DT.100820308

DT.99929812 DT.100820304 DT.100820317 DT.91964187 DT.100820309 DT.121390989 DT.100026114 DT.121390996

DT.91758535 DT.100820312 DT.121391039 DT.95367547 DT.100820307 DT.121390999 DT.121391019 DT.100820306

24/389 AceView cDNA sequences (see all 389):

AU133820 H27093 BQ942399 AI634632 BM683525 AI693604 AI582906 AK056851

AB024435 AW770538 C02390 BX279904 BF448185 BI761879 BI768269 AI753325

AI286175 BM827492 BM922744 BQ957173 BQ918131 CR599499 BU553804 BI907619

GeneLoc Exon Structure

5/22 Alternative Splicing Database (ASD) splice patterns (SP) for B4GALT3 (see all 22) About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	^	3a	·	3b	^	4	^	5a	·	5b	^	6	^	7a	·	7b	^	8a	·	8b	^	9	^	10a	·	10b	·	10c	^	11a	·	11b	·	11c	^	12a	·	12b	·	12c	^	13a	·	13b	·
SP1:					-		-		-		-		-		-		-								-																		-
SP2:					-		-		-		-		-		-		-								-
SP3:					-		-		-		-		-		-		-		-
SP4:					-		-		-		-		-		-		-								-
SP5:					-		-		-		-		-		-		-

ExUns:	13c	·	13d	^	14	^	15a	·	15b	^	16a	·	16b	·	16c
SP1:							-				-
SP2:							-
SP3:							-
SP4:							-
SP5:							-

ECgene alternative splicing isoforms for B4GALT3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

B4GALT3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGAGAAGAG

About this image
See B4GALT3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for B4GALT3

SOURCE GeneReport for Unigene cluster: Hs.321231

UniProtKB/Swiss-Prot: B4GT3_HUMAN, O60512

Tissue specificity: Found in various tissues. Highest expression in placenta, prostate, testis, ovary, intestine and

muscle, and in fetal brain

SABiosciences Expression via Pathway-Focused PCR Array including B4GALT3:

Glycosylation in human mouse rat

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for B4GALT3 gene from 6/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	LOC100858929¹	beta-1,4-galactosyltransferase 3-like	73.59(n) 81.42(a)		100858929 XM_003643241.1 XP_003643289.1
lizard (Anolis carolinensis)	Reptilia	B4GALT3⁶ --	--	67(a) 52(a)	1 ↔ 1 possible ortholog	GL343781.1(81922-95704) 3(181288192-181294468)
African clawed frog (Xenopus laevis)	Amphibia	BC041742.1²	--	73.81(n)		BC041742.1
zebrafish (Danio rerio)	Actinopterygii	LOC561756¹	beta-1,4-galactosyltransferase 3-like	63.9(n) 66.29(a)		561756 XM_685164.4 XP_690256.2
fruit fly (Drosophila melanogaster)	Insecta	BcDNA:GH13356³	beta-N-acetylglucosaminyl-glycopeptide beta-1,4-galactosyltransferase	41(a) (best of 2)		50E6 --
worm (Caenorhabditis elegans)	Secernentea	Y73E7A.7³	--	48(a) (best of 2)		I(1621527-1626606) --

ENSEMBL Gene Tree for B4GALT3 (if available)
TreeFam Gene Tree for B4GALT3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for B4GALT3 gene

B4GALT5² B4GALT2² B4GALT7² B4GALT4² B4GALT1² B4GALT6²

5 SIMAP similar genes for B4GALT3 using alignment to 1 protein entry: B4GT3_HUMAN:

B4GALT1 B4GALT4 B4GALT5 B4GALT2 B4GALT6

B4GALT3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
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SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs74124650^1,2	C,	--	132499541(+)	`GAAGGG/ATCACT`	3	--	int¹		1		WA	2
rs78050529^1,2		--	132499607(+)	`AAAAAA/GAAAAA`	3	--	int¹		0	--	--	--	--
rs12403282^1,2	C,F,H	--	132500195(+)	`TGGGTA/GTCCTA`	3	--	int¹		5		NS EA NA	420
rs112810680^1,2	C,F,	--	132500865(+)	`AAGGCC/TGGGCG`	3	--	int¹		1		NA	120
rs111611535^1,2		--	132500957(+)	`GCTAAC/TACGGT`	3	--	int¹		1		CSA	2
rs3813621^1,2	C,F,H,	--	132502071(+)	`GCTTAG/ATTCTC`	3	--	int¹		9		EA NS NA CSA WA	2382
rs112783273^1,2	C,	--	132503688(+)	`TCATGT/CGCCTG`	3	--	int¹		2		CSA WA	120
rs12031020^1,2	C,H	--	132503781(+)	`GGGGGT/AGGCGT`	3	--	int¹		4		NS EA	420
rs74124652^1,2	C,	--	132504305(+)	`GCACCG/CGGTCC`	3	--	ut5¹		1		WA	2
rs74124653^1,2	C,	--	132504339(+)	`TGTGAG/AGGAGC`	3	--	ut5¹		2		WA	120

HapMap Linkage Disequilibrium report for B4GALT3 (161141100 - 161147314 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for B4GALT3: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing B4GALT3

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

B4GALT3 for disorders           About GeneDecksing

OMIM gene information: 604014    OMIM disorders: --

7 diseases for B4GALT3:    About MalaCards

acute lymphoblastic leukemia lymphoblastic leukemia progeria burkitt's lymphoma

leukemia immunodeficiency prostatitis

Export disorders for B4GALT3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for B4GALT3 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with B4GALT3)

Utopia: connect your pdf to the dynamic
world of online information

A family of human beta4-galactosyltransferases. Cloning and expression of two novel UDP-galactose:beta-n-acetylglucosamine beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3. (PubMed id 9405390)^{1, 2, 3, 9} Almeida R.... Clausen H. (1997)
The expanding beta 4-galactosyltransferase gene family: messages from the databanks. (PubMed id 9597550)^{1, 2, 3} Lo N.-W.... Shaper N.L. (1998)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Galactosylation of N-linked oligosaccharides by human beta-1,4- galactosyltransferases I, II, III, IV, V, and VI expressed in Sf-9 cells. (PubMed id 11588157)^{1, 2} Guo S.... Furukawa K. (2001)
Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. (PubMed id 10580128)^{1, 2} Amado M.... Clausen H. (1999)
Comparison of HPLC/ESI-FTICR MS versus MALDI-TOF/TOF M S for glycopeptide analysis of a highly glycosylated HIV envelope glycoprotein. (PubMed id 18565761)¹ Irungu J....Desaire H. (2008)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
Tiling resolution array comparative genomic hybridization, expression and methylation analyses of dup(1q) in Burkitt lymphomas and pediatric high hyperdiploid acute lymphoblastic leukemias reveal clustered near-centromeric breakpoints and overexpression of genes in 1q22-32.3. (PubMed id 17613536)¹ Davidsson J....Johansson B. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 8703	HGNC: 926	AceView: B4GALT3	Ensembl:ENSG00000158850	euGenes: HUgn8703
ECgene: B4GALT3	Kegg: 8703	H-InvDB: B4GALT3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for B4GALT3	Pharmacogenomics, SNPs, Pathways
GGDB	http://riodb.ibase.aist.go.jp/rcmg/ggdb/
Functional Glycomics Gateway - GTase	http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_438

Intellectual Property for B4GALT3 gene
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Patent Information for B4GALT3 gene:
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GeneCards and IP:
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