B4GALT2 Gene
protein-coding GIFtS: 61
GCID: GC01P044444
|
|
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide...
| |
Aliases
for B4GALT2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase, Polypeptide 21 2 | | Beta-4-GalT21 | | Beta4Gal-T23 | | Beta-N-Acetylglucosaminyl-Glycolipid Beta-1,4-Galactosyltransferase 22 | | Beta-1,4-GalTase 22 3 | | UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase 22 | | UDP-Gal:Beta-GlcNAc Beta-1,4-Galactosyltransferase 22 3 | | UDP-Gal:BetaGlcNAc Beta 1,4-Galactosyltransferase, Polypeptide 22 | | UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,4-Galactosyltransferase 22 3 | | Beta4Gal-T23 | | B4Gal-T22 | | EC 2.4.1.-3 | | B4Gal-T32 | | B4Gal-T22 | | Beta-1,4-Galactosyltransferase 22 | | |
Export aliases for B4GALT2 gene to outside databasesPrevious GC identifers: GC01P044283 GC01P043445 GC01P043875 GC01P043858 GC01P044114 GC01P044217 GC01P042560 |
Summaries
for B4GALT2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for B4GALT2:
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-boundglycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactosein a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in thebiosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have anN-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remainsuncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this genesynthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected byalpha-lactalbumin but it is not expressed in lactating mammary tissue. Three transcript variants encoding twodifferent isoforms have been found for this gene. (provided by RefSeq, Jul 2011)
UniProtKB/Swiss-Prot: B4GT2_HUMAN, O60909Function: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as thecarbohydrate moieties of glycolipids. Can produce lactose
Gene Wiki entry for B4GALT2
|
Genomic Views
for B4GALT2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the B4GALT2 gene promoter:
E2F-3a E2F-4 FAC1 E2F E2F-1 E2F-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for B4GALT2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B4GALT2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p34-p33 Ensembl cytogenetic band: 1p34.1 HGNC cytogenetic band: 1p34-p33B4GALT2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P044444: view genomic region
(about GC identifiers)
Start:
|
44,444,615 bp from pter |
End:
|
44,456,840 bp from pter |
Size:
|
12,226 bases |
Orientation:
|
plus strand |
|
Proteins
for B4GALT2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: B4GT2_HUMAN, O60909 (See
protein sequence)Recommended Name: Beta-1,4-galactosyltransferase 2 Size: 372 amino acids; 41972 Da
Cofactor: Manganese (By similarity)
Subcellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternaeof Golgi stack
Secondary accessions: B3KTP0 B4DE14 D3DPY6 D3DPY7 O60511 Q4V9L9 Q5T4X5 Q5T4Y5 Q9BUP6 Q9NSY7Alternative splicing: 3 isoforms: O60909-1 O60909-2 O60909-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for B4GALT2: NX_O60909
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O60909
B4GALT2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001005417.1 NP_003771.1 NP_085076.2
ENSEMBL proteins: ENSP00000407468 ENSP00000349293 ENSP00000310696 ENSP00000361399 Reactome Protein details: O60909
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
B4GALT2 for ontologies About GeneDecksing
B4GALT2 Antibody Products:
Assay Products for B4GALT2: |
Protein
Domains /
Families
for B4GALT2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
B4GALT2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O60909ProtoNet protein and cluster: O60909 1 Blocks protein family: IPB003859 Metazoa galactosyltransferase
UniProtKB/Swiss-Prot: B4GT2_HUMAN, O60909Similarity: Belongs to the glycosyltransferase 7 family |
Function
for B4GALT2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: B4GT2_HUMAN, O60909Function: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as thecarbohydrate moieties of glycolipids. Can produce lactoseCatalytic activity: UDP-alpha-D-galactose + D-glucose = UDP + lactoseCatalytic activity: UDP-alpha-D-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP +beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptideCatalytic activity: UDP-alpha-D-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamineBiophysicochemical properties: Kinetic parameters: KM=71 uM for GlcNAc-B-S-pNP; Genatlas biochemistry entry for B4GALT2:UDP galactose
Enzyme Number (IUBMB): EC 2.4.1.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for B4GALT2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for B4GALT2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): B4GALT2 (NM_001005417) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for B4GALT2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat B4GALT2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B4GALT2 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity |
IEA | -- | | GO:0003945 | N-acetyllactosamine synthase activity |
IEA | -- | | GO:0004461 | lactose synthase activity |
IEA | -- | | GO:0008378 | galactosyltransferase activity |
TAS | 9405390 | | GO:0046872 | metal ion binding |
IEA | -- |
B4GALT2 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for B4GALT2:
Animal Models:
Mouse knock-out B4galt2tm1Masn for B4GALT2
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for B4galt2):
B4GALT2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for B4GALT2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | MPS IIIC - Sanfilippo syndrome C | | | 2 | Asparagine N-linked glycosylation | | | 3 | N-glycan antennae elongation in the medial/trans-Golgi | | | 4 | Keratan sulfate biosynthesis | | | 5 | Galactose metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for B4GALT2
1  GeneGo (Thomson Reuters) Pathway for B4GALT2
5/24 
Reactome Pathways for B4GALT2 (see all 24)
5/6 
Kegg Pathways (Kegg details for B4GALT2) (see all 6):
UniProtKB/Swiss-Prot: B4GT2_HUMAN, O60909Pathway: Protein modification; protein glycosylation
B4GALT2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for B4GALT2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 24)
5/24 Interacting proteins for B4GALT2 (ENSP000003492934) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005975 | carbohydrate metabolic process |
TAS | -- | | GO:0018146 | keratan sulfate biosynthetic process |
TAS | -- | | GO:0018279 | protein N-linked glycosylation via asparagine |
TAS | -- | | GO:0030203 | glycosaminoglycan metabolic process |
TAS | -- | | GO:0042339 | keratan sulfate metabolic process |
TAS | -- |
B4GALT2 for ontologies About GeneDecksing
|
Drugs & Compounds
for B4GALT2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for B4GALT2
7 HMDB Compounds for B4GALT2 About this table
1 DrugBank Compound for B4GALT2 About this table
Search CenterWatch for drugs/clinical trials and news about B4GALT2 / B4GT2
|
Transcripts
for B4GALT2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for B4GALT2 gene (3 alternative transcripts): NM_001005417.2 NM_003780.4 NM_030587.2 Unigene Cluster for B4GALT2: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 Hs.632403 [show with all ESTs]Unigene Representative Sequence: AK0958738 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000498543 ENST00000497866 ENST00000434555 ENST00000356836(uc010okl.2 uc001cli.3)
ENST00000485678 ENST00000481924 ENST00000309519 ENST00000372324(uc001clg.3 uc001clh.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for B4GALT2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for B4GALT2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): B4GALT2 (NM_001005417) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for B4GALT2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat B4GALT2 |
Additional cDNA sequence: AB024434.1 AF038660.1 AK074533.1 AK095873.1 AK293418.1 AL137647.1 BC002431.2 BC096821.1 Y12510.1 17 DOTS entries: DT.443441 DT.75103445 DT.86855255 DT.75193620 DT.95200940 DT.101954755 DT.86855254 DT.91769702 DT.100820346 DT.100820347 DT.100820349 DT.75103444 DT.92061753 DT.97812595 DT.101973129 DT.424518 DT.99937626 24/241 AceView cDNA sequences (see all 241): BM763130 AW296217 Y12510 AI950908 BM766234 AA759292 BQ940597 BE883853 AA577473 AL541643 BU947537 BQ654304 BM794874 AI361763 BM794222 BI914484 AW082085 CA432557 BG290123 AL138200 AL137647 AI150669 AW276110 CK818761
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for B4GALT2 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for B4GALT2
|
Expression
for B4GALT2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| B4GALT2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAGGCAGGT
About this image
See B4GALT2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for B4GALT2
SOURCE GeneReport for Unigene cluster: Hs.632403
UniProtKB/Swiss-Prot: B4GT2_HUMAN, O60909Tissue specificity: Weakly expressed in various tissues. Highest expression in prostate, testis, ovary, intestine,muscle, and in fetal brain
SABiosciences Expression via Pathway-Focused PCR Array including B4GALT2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for B4GALT2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat B4GALT2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat B4GALT2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat B4GALT2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B4GALT2 |
Orthologs
for B4GALT2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for B4GALT2 gene from 6/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
B4GALT21 |
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, more |
75.35(n)
78.12(a) |
|
396122 NM_205203.1 NP_990534.1 |
lizard
(Anolis carolinensis) |
Reptilia |
B4GALT26 |
-- |
73(a) |
1 ↔ 1 |
4(108899444-108908064) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BX848994.12 |
-- |
71.09(n) |
|
BX848994.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC1001488281 |
novel protein similar to vertebrate UDP-Gal:betaGlcNAc more |
69.11(n)
71(a) |
|
100148828 NM_001128385.1 NP_001121857.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
BcDNA:GH133563
beta4GalNAcTA1 |
beta-N-acetylglucosaminyl-glycopeptide
beta-1,4-galactosyltransferase3
CG8536-PA1 |
39(a)
(best of 2)3
50.3(n)1
41.64(a)1 |
|
50E63
365851 NM_137102.31 NP_610946.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y73E7A.73
bre-41 |
Protein BRE-41 |
43(a)
(best of 2)3
45.24(n)1
37.75(a)1 |
|
I(1621527-1626606)3
1906681 NM_058471.11 NP_490872.11 |
ENSEMBL Gene Tree for B4GALT2 (if available)
TreeFam Gene Tree for B4GALT2 (if available) |
Paralogs
for B4GALT2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for B4GALT2 gene
- B4GALT52 B4GALT72 B4GALT12 B4GALT42 B4GALT62 B4GALT32
5 SIMAP similar genes for B4GALT2 using alignment to 1 protein entry: B4GT2_HUMAN:B4GALT1 B4GALT4 B4GALT5 B4GALT3 B4GALT6
B4GALT2 for paralogs About GeneDecksing
|
Genomic Variants
for B4GALT2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for B4GALT2 (44444615 - 44456840 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for B4GALT2
1 CNV: 84203 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing B4GALT2 |
|
Disorders
/ Diseases
for B4GALT2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
B4GALT2 for disorders About GeneDecksing
OMIM gene information: 604013
OMIM disorders: --
5  diseases for B4GALT2: About MalaCardsdiabetic retinopathy retinitis immunodeficiency prostatitis
neuronitis
Export disorders for B4GALT2 gene to outside databases
|
Publications
for B4GALT2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for B4GALT2 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with B4GALT2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A family of human beta4-galactosyltransferases. Cloning and expression of two novel UDP-galactose:beta-n-acetylglucosamine beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3. (PubMed id 9405390)1, 2, 3, 9 Almeida R.... Clausen H. (1997)
- The expanding beta 4-galactosyltransferase gene family: messages from the databanks. (PubMed id 9597550)1, 2, 3 Lo N.-W.... Shaper N.L. (1998)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Galactosylation of N-linked oligosaccharides by human beta-1,4- galactosyltransferases I, II, III, IV, V, and VI expressed in Sf-9 cells. (PubMed id 11588157)1, 2 Guo S.... Furukawa K. (2001)
- Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. (PubMed id 10580128)1, 2 Amado M.... Clausen H. (1999)
- Site directed processing: role of amino acid sequence s and glycosylation of acceptor glycopeptides in the assembly of extended mucin type O-glycan core 2. (PubMed id 19524017)1 Brockhausen I....Paulsen H. (2009)
- Comparison of HPLC/ESI-FTICR MS versus MALDI-TOF/TOF M S for glycopeptide analysis of a highly glycosylated HIV envelope glycoprotein. (PubMed id 18565761)1 Irungu J....Desaire H. (2008)
- Identification of {beta}1,4GalT II as a Target Gene of p53-mediated HeLa Cell Apoptosis. (PubMed id 18211920)1 Zhou J....Gu J. (2008)
|
External Searches for B4GALT2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing B4GALT2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing B4GALT2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing B4GALT2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for B4GALT2 | Pharmacogenomics, SNPs, Pathways | | GGDB | http://riodb.ibase.aist.go.jp/rcmg/ggdb/ | | Functional Glycomics Gateway - GTase | http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_437 |
|
| | |
About This Section
| Patent Information for B4GALT2 gene:
Search GeneIP for patents involving B4GALT2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for B4GALT2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for B4GALT2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for B4GALT2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for B4GALT2 | | | OriGene Protein Over-expression Lysate for B4GALT2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for B4GALT2 | | OriGene 3'-UTR Clone for B4GALT2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for B4GALT2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for B4GALT2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for B4GALT2 | | OriGene Custom Protein Services for B4GALT2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat B4GALT2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing B4GALT2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B4GALT2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat B4GALT2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat B4GALT2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat B4GALT2 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for B4GALT2 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B4GALT2 |
|  |  |  | | | | ThermoFisher Antibodies for B4GALT2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat B4GALT2 |
|
|
|
|
