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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

B4GALNT2 Gene

protein-coding   GIFtS: 50
GCID: GC17P047210

Beta-1,4-N-Acetyl-Galactosaminyl Transferase 2

(Previous name: UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase)
(Previous symbol: GALGT2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Beta-1,4-N-Acetyl-Galactosaminyl Transferase 21 2     Beta-1,4 N-Acetylgalactosaminyltransferase 22
GALGT21 2 3 5     beta-4-N-acetylgalactosaminyltransferase2
UDP-GalNAc:Neu5Acalpha2-3Galbeta-R
Beta1,4-N-Acetylgalactosaminyltransferase1 2
     Sda Beta-1,4-GalNAc Transferase2
Sd(A) Beta-1,4-GalNAc Transferase2 3     EC 2.4.1.-3
UDP-GalNAc:Neu5Aca2-3Galb-R B1,4-N-Acetylgalactosaminyltransferase2 3     B4GALGT25
B4GALT2     SD5
Beta 1,4 N-Acetylgalactosaminyltransferase/Betal,4 GalNAcT/Sda-GalNAcT2     EC 2.4.1.928

External Ids:    HGNC: 241361   Entrez Gene: 1248722   Ensembl: ENSG000001670807   OMIM: 1117305   UniProtKB: Q8NHY03   

Export aliases for B4GALNT2 gene to outside databases

Previous GC identifers: GC17P044566 GC17P042576


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for B4GALNT2 Gene:
B4GALNT2 catalyzes the last step in the biosynthesis of the human Sd(a) antigen through the addition of an
N-acetylgalactosamine residue via a beta-1,4 linkage to a subterminal galactose residue substituted with an
alpha-2,3-linked sialic acid. B4GALNT2 also catalyzes the last step in the biosynthesis of the Cad antigen
(Montiel et al., 2003 (PubMed 12678917)).(supplied by OMIM, Mar 2008)

GeneCards Summary for B4GALNT2 Gene: 
B4GALNT2 (beta-1,4-N-acetyl-galactosaminyl transferase 2) is a protein-coding gene. Diseases associated with B4GALNT2 include phaeohyphomycosis, and dermatophytosis. GO annotations related to this gene include acetylgalactosaminyltransferase activity. An important paralog of this gene is B4GALNT1.

UniProtKB/Swiss-Prot: B4GN2_HUMAN, Q8NHY0
Function: Involved in the synthesis of the Sd(a) antigen (Sia-alpha2,3-[GalNAc-beta1,4]Gal-beta1,4-GlcNAc), a
carbohydrate determinant expressed on erythrocytes, the colonic mucosa and other tissues. Transfers a
beta-1,4-linked GalNAc to the galactose residue of an alpha-2,3-sialylated chain

Gene Wiki entry for B4GALNT2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the B4GALNT2 gene promoter:
         STAT5B   Nkx3-1   Nkx3-1 v4   HTF   Nkx3-1 v1   Nkx3-1 v2   POU2F1   Nkx6-1   POU2F1a   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidB4GALNT2 promoter sequence
   Search SABiosciences Chromatin IP Primers for B4GALNT2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B4GALNT2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.32   Ensembl cytogenetic band:  17q21.32   HGNC cytogenetic band: 17q21.33

B4GALNT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B4GALNT2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P047210:  view genomic region     (about GC identifiers)

Start:
47,209,822 bp from pter      End:
47,247,351 bp from pter
Size:
37,530 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: B4GN2_HUMAN, Q8NHY0 (See protein sequence)
Recommended Name: Beta-1,4 N-acetylgalactosaminyltransferase 2  
Size: 566 amino acids; 63258 Da
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (Potential)
Secondary accessions: B4DZE4 Q14CP1 Q86Y40
Alternative splicing: 3 isoforms:  Q8NHY0-1   Q8NHY0-2   Q8NHY0-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for B4GALNT2: NX_Q8NHY0

Explore proteomics data for B4GALNT2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NHY0

  • 4 DME Specific Peptides for B4GALNT2 (Q8NHY0)
     VGFDPRL  GVVNFFLA  MPFGKGWFAGRNLA  SQVTTKYVLWVDDDF 

    B4GALNT2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    B4GALNT2 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001152859.1  NP_001152860.1  NP_703147.2  

    ENSEMBL proteins: 
     ENSP00000425510   ENSP00000377022   ENSP00000300404  

    Human Recombinant Protein Products for B4GALNT2: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane NAS12678917
    GO:0030173integral to Golgi membrane IEA--

    B4GALNT2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    GLT2: Glycosyltransferase family 2 domain containing
    B4GT: Beta 4-glycosyltransferases

    2 InterPro protein domains:
     IPR011143 GM2_synthase
     IPR001173 Glyco_trans_2

    Graphical View of Domain Structure for InterPro Entry Q8NHY0

    ProtoNet protein and cluster: Q8NHY0

    1 Blocks protein domain: IPB001173 Glycosyl transferase

    UniProtKB/Swiss-Prot: B4GN2_HUMAN, Q8NHY0
    Similarity: Belongs to the glycosyltransferase 2 family


    B4GALNT2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: B4GN2_HUMAN, Q8NHY0
    Function: Involved in the synthesis of the Sd(a) antigen (Sia-alpha2,3-[GalNAc-beta1,4]Gal-beta1,4-GlcNAc), a
    carbohydrate determinant expressed on erythrocytes, the colonic mucosa and other tissues. Transfers a
    beta-1,4-linked GalNAc to the galactose residue of an alpha-2,3-sialylated chain

         Enzyme Numbers (IUBMB): EC 2.4.1.922 EC 2.4.1.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008376acetylgalactosaminyltransferase activity IDA12678917
    GO:0016758transferase activity, transferring hexosyl groups ----
         
    B4GALNT2 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 3 alleles(MGI details for B4galnt2):
     cellular  digestive/alimentary  no phenotypic analysis 

    B4GALNT2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out B4galnt2tm1Jbl for B4GALNT2

       inGenious Targeting Laboratory - Custom generated mouse model solutions for B4GALNT2 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for B4GALNT2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for B4GALNT2 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B4GALNT2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: B4GN2_HUMAN, Q8NHY0
    Pathway: Protein modification; protein glycosylation

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for B4GALNT2

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006047UDP-N-acetylglucosamine metabolic process IEA--
    GO:0006486protein glycosylation IEA--
    GO:0019276UDP-N-acetylgalactosamine metabolic process IDA12678917
    GO:0022408negative regulation of cell-cell adhesion IDA16024623
    GO:0030259lipid glycosylation IEA--

    B4GALNT2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for B4GALNT2 (B4GN2)

    1 HMDB Compound for B4GALNT2    About this table
    CompoundSynonyms CAS #PubMed Ids
    N-Acetylgalactosamine2-Acetamido-2-desoxy-b-D-talofuranose (see all 113)1811-31-0--

    Search CenterWatch for drugs/clinical trials and news about B4GALNT2 / B4GN2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for B4GALNT2 gene (3 alternative transcripts): 
    NM_001159387.1  NM_001159388.1  NM_153446.2  

    Unigene Cluster for B4GALNT2:

    Beta-1,4-N-acetyl-galactosaminyl transferase 2
    Hs.374679  [show with all ESTs]
    Unigene Representative Sequence: NM_153446
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000504681(uc010wlt.1 uc010wlu.1) ENST00000393354 ENST00000300404(uc002ion.2)

    miRNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat B4GALNT2
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    Additional mRNA sequence: 

    AF510036.1 AJ517770.1 AJ517771.1 AK302876.1 BC113675.1 BC113677.1 S83275.1 

    2 DOTS entries:

    DT.91879225  DT.406872 

    5 AceView cDNA sequences:

    AJ517770 S83275 AF510036 AJ517771 NM_153446 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    B4GALNT2 expression in normal human tissues (normalized intensities)      B4GALNT2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCAGAAGTG
    B4GALNT2 Expression
    About this image


    B4GALNT2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/19 selected tissues (see all 19) fully expand
     
     Colon (Gastrointestinal Tract)    fully expand to see all 3 entries
             colon ; peripheral nerve/ganglion   
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             seminal vesicle ; glandular cells   
     
     Uterus (Reproductive System)    fully expand to see all 2 entries
             uterus, post-menopause ; glandular cells   
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 2 entries
             placenta ; decidual cells   
     
     Stomach (Gastrointestinal Tract)    fully expand to see all 2 entries
             stomach, upper ; glandular cells   

    See B4GALNT2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for B4GALNT2

    SOURCE GeneReport for Unigene cluster: Hs.374679

    UniProtKB/Swiss-Prot: B4GN2_HUMAN, Q8NHY0
    Tissue specificity: Widely expressed. Highly expressed in colon and to a lesser extent in kidney, stomach, ileum
    and rectum

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for B4GALNT2 gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia B4galnt21 , 5 beta-1,4-N-acetyl-galactosaminyl transferase 21, 5 78.82(n)1
    74.55(a)1
      11 (59.02 cM)5
    144221  NM_008081.31  NP_032107.11 
     958659435 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    Uncharacterized protein
    (see all 3)
    53(a)
    52(a)
    (see all 3)
    1 ↔ many
    1 ↔ many
    (see all 3)
    GL343631.1(20561-21943)
    3(174465558-174466841)
    zebrafish
    (Danio rerio)
    Actinopterygii b4galnt26
    CABZ01039859.16
    (see all 3)
    Uncharacterized protein
    (see all 3)
    41(a)
    37(a)
    (see all 3)
    1 ↔ many
    1 ↔ many
    (see all 3)
    3(23360963-23376843)
    25(5643727-5665767)


    ENSEMBL Gene Tree for B4GALNT2 (if available)
    TreeFam Gene Tree for B4GALNT2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for B4GALNT2 gene
    B4GALNT12  
    1 SIMAP similar gene for B4GALNT2 using alignment to 1 protein entry:     B4GN2_HUMAN:
    B4GALNT1

    B4GALNT2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for B4GALNT2
    PGOHUM00000237430


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/969 SNPs in B4GALNT2 are shown (see all 969)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0359904
    A colorectal cancer sample4--see VAR_0359902 P H mis40--------
    rs1455565191,2
    C--47207889(+) CAGCTA/TCTTAG 1 -- us2k10--------
    rs1899663301,2
    --47207925(+) AACCCA/GGGAGG 1 -- us2k10--------
    rs20910391,2
    C,F,A,H--47207963(+) ccactA/Gcactc 1 -- us2k16Minor allele frequency- G:0.29NA 14
    rs20910401,2
    C,F,A,H--47208076(+) attgtT/Cgcaga 1 -- us2k131Minor allele frequency- C:0.40NS EA NA WA 2856
    rs1453424411,2
    --47208140(+) TTTTGC/TCCAAG 2 -- us2k10--------
    rs46210141,2
    H--47208215(+) cacttC/Ttaagt 2 -- us2k14Minor allele frequency- T:0.00NS EA 418
    rs1378851711,2
    --47208261(+) TTTGTC/GTACCT 2 -- us2k10--------
    rs1116302391,2
    F--47208345(+) GTGATG/ACAGGG 3 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1156024601,2
    C,F--47208384(+) AGACAC/TAACTC 3 -- us2k11Minor allele frequency- T:0.03WA 118

    HapMap Linkage Disequilibrium report for B4GALNT2 (47209822 - 47247351 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for B4GALNT2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2911CNV Deletion18987735
    esv2478586CNV Deletion19546169
    esv2445547CNV Deletion19546169
    esv1972485CNV Deletion18987734
    esv2716020CNV Deletion23290073
    esv1011150CNV Deletion20482838
    esv1351644CNV Deletion17803354
    esv9571CNV Loss19470904

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 111730    OMIM disorders: --

    5 diseases for B4GALNT2:    About MalaCards
    phaeohyphomycosis    dermatophytosis    tracheitis    dacryoadenitis
    gonorrhea

    2 diseases from the University of Copenhagen DISEASES database for B4GALNT2:
    Dermatophytosis     Tracheitis

    B4GALNT2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): B4GALNT2
    Human Genome Epidemiology (HuGE) Navigator: B4GALNT2 (1 document)

    Export disorders for B4GALNT2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for B4GALNT2 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with B4GALNT2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain. (PubMed id 12678917)1, 2, 3, 9 Montiel M.D....Harduin-Lepers A. (2003)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Molecular cloning of the human beta1,4 N- acetylgalactosaminyltransferase responsible for the biosynthesis of the Sd(a) histo-blood group antigen: the sequence predicts a very long cytoplasmic domain. (PubMed id 14688233)1, 2 Lo Presti L.... Dall'Olio F. (2003)
    5. Detection of N-acetylgalactosaminyltransferase mRNA which determines expression of Sda blood group carbohydrate structure in human gastrointestinal mucosa and cancer. (PubMed id 8782649)1, 3 Dohi T.... Oshima M. (1996)
    6. DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer. (PubMed id 18485915)1, 9 Kawamura Y.I....Dohi T. (2008)
    7. Identification of 23 new prostate cancer susceptibilit y loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (2013)
    8. Expression of the human Sd(a) beta-1,4-N-acetylgalactosaminyltransferase II gene is dependent on the promoter methylation status. (PubMed id 17965433)1 Wang H.R....Yu L.C. (2008)
    9. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    10. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 124872 HGNC: 24136 AceView: GALGT2 Ensembl:ENSG00000167080 euGenes: HUgn124872
    ECgene: B4GALNT2 H-InvDB: B4GALNT2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for B4GALNT2 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_482

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for B4GALNT2 gene:
    Search GeneIP for patents involving B4GALNT2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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