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B4GALNT1 Gene

protein-coding GIFtS: 54

GC12M056306

beta-1,4-N-acetyl-galactosaminyl transferase 1
(Previous names: UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase (GalNAc-T), UDP-Gal:betaGlcNAc beta-1,4-N-acetylgalactosaminyltransferase transferase 1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: GALGT)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
(N-acetylneuraminyl)-galactosylglucosylceramide ^³
EC 2.4.1.92 ^³
GALGT ^², ³
GALNACT ^²
GalNAc-T ^², ³
SIAT2 ^³
beta1,4GalNAc-T ^²
beta1-4GalNAc-T ^¹, ²

Descriptions
GD2 synthase, GM2 synthase ^²
GM2/GD2 synthase ^³
UDP-Gal:betaGlcNAc beta-1,4-N-acetylgalactosaminyltransferase transferase 1 ^¹, ²
UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase (GalNAc-T) ^¹, ²
beta-1,4-N-acetyl-galactosaminyl transferase 1 ^²

External Ids
HGNC: 4117¹
Entrez Gene: 2583²
UniProtKB: Q00973³
Ensembl: ENSG00000135454⁷

Search outside databases for aliases for B4GALNT1 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for B4GALNT1:

GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme

involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the

transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2)

and G(D2), respectively. [provided by RefSeq]

UniProtKB/Swiss-Prot: B4GN1_HUMAN, Q00973

Function: Involved in the biosynthesis of gangliosides GM2, GD2 and GA2

Gene Wiki entry for B4GALNT1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the B4GALNT1 gene

Entrez Gene cytogenetic band: 12q13.3 Ensembl cytogenetic band: 12q14.1 HGNC cytogenetic band: 12q13.3

B4GALNT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M056306: (about GC identifiers)

Start:	56,305,818 bp from pter
End:	56,313,252 bp from pter
Size:	7,435 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000012.10 NT_029419.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: B4GN1_HUMAN, Q00973 (See protein sequence)

Recommended Name: Beta-1,4 N-acetylgalactosaminyltransferase 1

Size: 533 amino acids; 58882 Da

Subunit: Homodimer; disulfide-linked

Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein

REFSEQ proteins: NP_001469.1

ENSEMBL proteins:

ENSP00000341562

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (B4GALNT1)
	Human Recombinant Proteins from Abnova (B4GALNT1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5/6 Gene Ontology (GO) cellular component terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	IEA	--
GO:0005624	membrane fraction	TAS	1601877
GO:0005794	Golgi apparatus	IEA	--
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

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Antibodies for B4GALNT1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for B4GALNT1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (B4GALNT1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (B4GALNT1)
	Novus Biologicals Antibodies for B4GALNT1

Assays for B4GALNT1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q00973

ProtoNet protein and cluster: Q00973

1 Blocks protein family: IPB001173 Glycosyl transferase

UniProtKB/Swiss-Prot: B4GN1_HUMAN, Q00973

Similarity: Belongs to the glycosyltransferase 2 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (B4GALNT1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (B4GALNT1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001478

Applied Biosystems Silencer® siRNAs for B4GALNT1

Sigma-Aldrich siRNA for B4GALNT1

Sigma-Aldrich shRNA for B4GALNT1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for B4GALNT1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001478
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001478
untagged cDNA clone in CMV expression vector: NM_001478

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001478

UniProtKB/Swiss-Prot: B4GN1_HUMAN, Q00973

Function: Involved in the biosynthesis of gangliosides GM2, GD2 and GA2

Catalytic activity: UDP-N-acetyl-D-galactosamine +

1-O-(O-(N-acetyl-alpha-neuraminosyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl)-ceramide

= UDP +

1-O-(O-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl-(1->4)-O-(N-acetyl-alpha-neuraminosyl-(2->3))-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl)-ceramide

Enzyme Number (IUBMB): EC 2.4.1.92

8 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for B4galnt1):

behavior/neurological	endocrine/exocrine gland	hematopoietic system	immune system	life span-post-weaning/aging
nervous system	renal/urinary system	reproductive system

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003947	(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity	TAS	8702839
GO:0016758	transferase activity, transferring hexosyl groups	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for B4GALNT1 (Your Favorite Gene powered by Ingenuity)

Glycosphingolipid Biosynthesis - Ganglioseries

GeneDecks B4GALNT1 for the pathways selected above

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UniProtKB/Swiss-Prot: B4GN1_HUMAN, Q00973

Pathway: Protein modification; protein glycosylation

5/25 Interacting proteins for B4GALNT1 (ENSP00000341562³) via UniProtKB, MINT, and/or STRING (see all 25 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ST8SIA1	ENSP00000261197³	STRING (score=.972)
CHPF	ENSP00000243776³	STRING (score=.968)
ST3GAL5	ENSP00000366549³	STRING (score=.955)
GALNT1	ENSP00000269195³	STRING (score=.947)
GBGT1	ENSP00000361113³	STRING (score=.92)

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5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001574	ganglioside biosynthetic process	IEA	--
GO:0005975	carbohydrate metabolic process	TAS	1601877
GO:0006687	glycosphingolipid metabolic process	TAS	1601877
GO:0019915	lipid storage	IEA	--
GO:0030259	lipid glycosylation	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
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Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for B4GALNT1
3 Novoseek chemical compound relationships for B4GALNT1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
asialo gm2	83.41	2	7890749 (1), 8737246 (1)
ganglioside	81.49	8	9639544 (1), 7533654 (1), 9930722 (1), 10820196 (1) (see all 5)
tyrosine	4.47	2	18520032 (1), 16384890 (1)

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(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (B4GALNT1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (B4GALNT1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001478

Sigma-Aldrich siRNA for B4GALNT1

Sigma-Aldrich shRNA for B4GALNT1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001478

REFSEQ mRNAs for B4GALNT1 gene:

NM_001478.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001478

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001478
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001478
                                 untagged cDNA clone in CMV expression vector: NM_001478

Additional cDNA sequence:

AB209460.1 AK127448.1 AK289690.1 AK293432.1 AK299845.1 AK302503.1 BC029828.1 CR610248.1

CR622992.1 M83651.1

10 DOTS entries:

DT.309821 DT.97796097 DT.423176 DT.100775139 DT.99969655 DT.86854056 DT.97837287 DT.95162962

DT.97810499 DT.102841116

24/72 AceView cDNA sequences (see all 72 ):

CK300234 CA431063 BE547617 BM827399 BQ943591 BM740142 CR622992 M83651

CB154451 BU615671 AI913075 CR610248 BQ647977 BU632715 AL520907 BC029828

AI360246 AI084079 AA779389 BM758410 BU634463 BI824495 R48319 BI915530

highest scoring ESTs for B4GALNT1:

M83651 AI497617 BC029828 BI757908 BI824495 BI824524 BI915530 BM807649 BM921444 BM922063

Unigene Cluster for B4GALNT1:

Beta-1,4-N-acetyl-galactosaminyl transferase 1

Hs.591019 [show with all ESTs]

Unigene Representative Sequence: AB209460

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for B4GALNT1 (see all 12 )

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	·	2c	^	3	^	4	^	5a	·	5b	·	5c	^	6a	·	6b	^	7	^	8	^	9	^	10a	·	10b	^	11	^	12	^	13	^	14a	·	14b	·	14c	^	15a	·	15b	·
SP1:							-		-		-										-
SP2:																					-										-		-
SP3:							-		-		-										-
SP4:																					-
SP5:																															-

ExUns:	15c
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for B4GALNT1

1 Ensembl transcript including schematic representation:

ENST00000341156

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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B4GALNT1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for B4GALNT1

¹ / ² / ³

5 probe-sets matching B4GALNT1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
51917_at²^{, 3}	U95-C	1	1.00	1.00	0.97	1.35	AI497617	0.80	1.00	0.91	1
38212_at²^{, 3}	U95-A	1	0.62	1.00	0.93	0.66	M83651	1.00	1.00	1.00	1
206435_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001478	0.60	1.00	0.82	1
1555385_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
206435_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks B4GALNT1 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
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About these images

CGAP SAGE TAG: GGGATAAAAT

SOURCE GeneReport for Unigene cluster: Hs.591019

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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Orthologs for B4GALNT1 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	B4GALNT1¹	--	beta-1,4-N-acetyl-galactosaminyl transferase 1	89.81(n) 92.68(a)	481129 XM_538250.2 XP_538250.2
chimpanzee (Pan troglodytes)	B4GALNT1¹	--	beta-1,4-N-acetyl-galactosaminyl transferase 1	99.69(n) 99.81(a)	452021 XM_509169.2 XP_509169.2
cow (Bos taurus)	B4GALNT1¹	--	beta-1,4-N-acetyl-galactosaminyl transferase 1	88.93(n) 90.99(a)	520159 NM_001017943.1 NP_001017943.1
rat (Rattus norvegicus)	B4galnt1¹	--	beta-1,4-N-acetyl-galactosaminyl transferase 1	84.55(n) 87.62(a)	64828 NM_022860.2 NP_074051.1
mouse (Mus musculus)	B4galnt1^{1, 5}	10 (69.25 cM)⁵	beta-1,4-N-acetyl-galactosaminyl transferase 1^{1, 5}	84.8(n)¹ 86.87(a)¹	14421¹ NM_008080.4¹ NP_032106.1¹ AK016978⁵ AK040324⁵ (see all 13)

About this table Species with no ortholog for B4GALNT1

ENSEMBL Gene Tree for B4GALNT1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
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Paralogs for B4GALNT1 gene

B4GALNT2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
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10/55 NCBI SNPs in B4GALNT1 are shown (see all 55 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 48)

AB	SNP ID	Valid	Chr 12 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs774896^1,2	A,C,F,H	56312080(+)	`AGGTAC/GCCGGA`	1	L/V	mis¹ ese³		5		MN EA WA	530
	rs774899^1,2	A,C,F,H	56313348(+)	`AGCCTC/TCAAAC`	1	--	ng3¹		9		MN EU EA WA NA	950
	rs17454674^1,2	C,F,H	56306849(+)	`GTTTGG/ACCATC`	1	V/A	mis¹		11		NA EU EA WA	968
	rs774898^1,2	A,C,F	56313053(+)	`TGCCCG/TGGGGC`	1	--	ut5¹ ese³		1		MN	184
--	rs6581147^1,2	A,C	56315130(+)	`aaatgC/Ttcccc`	1	--	ng3¹		0	--	--	--	--
	rs810205^1,2	F,H	56310545(+)	`CTGACC/GAGAAG`	1	G/R	mis¹ ese³		7		MN EU EA WA NA	642
	rs2619468^1,2	A,C	56313574(+)	`CCTCTA/CCCCCT`	1	--	ng3¹ trp³		0	--	--	--	--
--	rs3899676^1,2	A	56314183(+)	`gcaagA/Gtggct`	1	--	ng3¹		0	--	--	--	--
--	rs12578587^1,2	C	56315013(+)	`tattcC/Gttgca`	1	--	ng3¹		0	--	--	--	--
--	rs4397894^1,2	A	56314316(+)	`ctgtcC/Tcaaaa`	1	--	ng3¹		0	--	--	--	--

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HapMap Linkage Disequilibrium images for B4GALNT1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 601873

7 Novoseek disease relationships for B4GALNT1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
melanoma	31.76	3	9930722 (1), 7487055 (1), 17634536 (1)
gastric cancer	26.17	3	11914601 (1), 7533654 (1)
colon cancer	15.01	1	11914601 (1)
cancer lung	2.27	1	11914601 (1)
breast cancer	0.37	2	11914601 (1), 17634536 (1)
cancer	0.00	8	11914601 (4), 17634536 (1)
carcinoma	0.00	2	11914601 (1), 7533654 (1)

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Human Genome Epidemiology Navigator: B4GALNT1 (1 document)

(Possibly Related Articles in Doctor's Guide)
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(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/42 PubMed articles for B4GALNT1 gene (see all 42 ):

Expression cloning of beta 1,4 N-acetylgalactosaminyltransferase cDNAs that determine the expression of GM2 and GD2 gangliosides. (PubMed id 1601877)^{2, 3, 4} Nagata Y.... Furukawa K. (1992)
Disulfide bonds of GM2 synthase homodimers. Antiparallel orientation of the catalytic domains. (PubMed id 11018043)^{3, 4} Li J.... Young W.W. Jr. (2000)
Expression cloning of beta 1,4 N-acetylgalactosaminyltransferase cDNAs that determine the expression of GM2 and GD2 gangliosides. (PubMed id 8120069)^{3, 4} Nagata Y.... Furukawa K. (1994)
Glycosyltransferase B4GALNT1 and type 1 diabetes in Croatian population: clinical investigation. (PubMed id 19318031)^{1, 3} Boraska V....Zemunik T. (2009)
Evaluation of SAT-1, SAT-2 and GalNAcT-1 mRNA in colon cancer by real-time PCR. (PubMed id 17119850)³ Gornati R....Bernardini G. (2007)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)
Brain-specific expression of a novel human UDP-GalNAc:polypeptide N- acetylgalactosaminyltransferase (GalNAc-T9). (PubMed id 10978536)³ Toba S.... Kurosaka A. (2000)
GA2/GM2/GD2 synthase localizes to the trans-golgi network of CHO-K1 cells. (PubMed id 10477274)³ Giraudo C.G....Maccioni H.J. (1999)
Genomic organization and chromosomal assignment of the human beta1, 4-N-acetylgalactosaminyltransferase gene. Identification of multiple transcription units. (PubMed id 8702839)³ Furukawa K....Shiku H. (1996)
Beta1,4-N-acetylgalactosaminyltransferase (GM2 synthase) is released from Golgi membranes as a neuraminidase-sensitive, disulfide-bonded dimer by a cathepsin D-like protease. (PubMed id 8824296)³ Jaskiewicz E....Young W.W. (1996)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 2583	HGNC: 4117	AceView: GALGT	Ensembl:ENSG00000135454	euGenes: HUgn2583
ECgene: B4GALNT1	H-InvDB: B4GALNT1

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
GGDB	http://riodb.ibase.aist.go.jp/rcmg/ggdb/
Functional Glycomics Gateway - GTase	http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_480

Licensable Technologies for B4GALNT1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for B4GALNT1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for B4GALNT1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for B4GALNT1		Antibodies for B4GALNT1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for B4GALNT1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (B4GALNT1)
	Antibodies (B4GALNT1)
	Chimera RNAi (B4GALNT1)
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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B4GALNT1 Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for B4GALNT1

Summaries
for B4GALNT1

Genomic Location
for B4GALNT1

Proteins
for B4GALNT1

Protein Domains/
Families
for B4GALNT1

Gene Function
for B4GALNT1

Pathways & Interactions
for B4GALNT1

Drugs & Compounds
for B4GALNT1

Transcripts
for B4GALNT1

Expression
for B4GALNT1

Orthologs
for B4GALNT1

Paralogs
for B4GALNT1

SNPs/Variants
for B4GALNT1

Disorders & Mutations
for B4GALNT1

Medical News
for B4GALNT1

Publications
for B4GALNT1

Search for B4GALNT1

Genome Databases showing B4GALNT1

Other Databases showing B4GALNT1

Specialized Databases showing B4GALNT1

Licensable Technologies
for B4GALNT1

Services
for B4GALNT1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

B4GALNT1 Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor B4GALNT1

Summariesfor B4GALNT1

Genomic Locationfor B4GALNT1

Proteinsfor B4GALNT1

Protein Domains/Familiesfor B4GALNT1

Gene Functionfor B4GALNT1

Pathways & Interactionsfor B4GALNT1

Drugs & Compoundsfor B4GALNT1

Transcriptsfor B4GALNT1

Expression for B4GALNT1

Orthologsfor B4GALNT1

Paralogsfor B4GALNT1

SNPs/Variantsfor B4GALNT1

Disorders & Mutationsfor B4GALNT1

Medical Newsfor B4GALNT1

Publicationsfor B4GALNT1

Search for B4GALNT1

Genome Databases showing B4GALNT1

Other Databases showing B4GALNT1

Specialized Databases showing B4GALNT1

Licensable Technologiesfor B4GALNT1

Servicesfor B4GALNT1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for B4GALNT1

Summaries
for B4GALNT1

Genomic Location
for B4GALNT1

Proteins
for B4GALNT1

Protein Domains/
Families
for B4GALNT1

Gene Function
for B4GALNT1

Pathways & Interactions
for B4GALNT1

Drugs & Compounds
for B4GALNT1

Transcripts
for B4GALNT1

Expression
for B4GALNT1

Orthologs
for B4GALNT1

Paralogs
for B4GALNT1

SNPs/Variants
for B4GALNT1

Disorders & Mutations
for B4GALNT1

Medical News
for B4GALNT1

Publications
for B4GALNT1

Licensable Technologies
for B4GALNT1

Services
for B4GALNT1