Aliases for B4GALNT1 Gene
Aliases for B4GALNT1 Gene
- Beta-1,4-N-Acetyl-Galactosaminyltransferase 1 2 3 5
- UDP-N-Acetyl-Alpha-D-Galactosamine:(N-Acetylneuraminyl)-Galactosylglucosylceramide N-Acetylgalactosaminyltransferase (GalNAc-T) 2 3
- UDP-Gal:BetaGlcNAc Beta-1,4-N-Acetylgalactosaminyltransferase Transferase 1 2 3
- GD2 Synthase, GM2 Synthase 2 3
- GM2/GD2 Synthase 3 4
- EC 2.4.1.92 4 61
- GalNAc-T 3 4
- GALGT 3 4
- (N-Acetylneuraminyl)-Galactosylglucosylceramide 4
External Ids for B4GALNT1 Gene
- HGNC: 4117
- Entrez Gene: 2583
- Ensembl: ENSG00000135454
- OMIM: 601873
- UniProtKB: Q00973
Previous HGNC Symbols for B4GALNT1 Gene
- GALGT
- SPG26
Previous GeneCards Identifiers for B4GALNT1 Gene
- GC12M056306
- GC12M058019
- GC12M055057
Summaries for B4GALNT1 Gene
-
GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
GeneCards Summary for B4GALNT1 Gene
B4GALNT1 (Beta-1,4-N-Acetyl-Galactosaminyltransferase 1) is a Protein Coding gene. Diseases associated with B4GALNT1 include Spastic Paraplegia 26, Autosomal Recessive and Spastic Paraplegia 26. Among its related pathways are Glycosphingolipid biosynthesis - ganglio series and Metabolism. GO annotations related to this gene include transferase activity and acetylgalactosaminyltransferase activity. An important paralog of this gene is B4GALNT2.
UniProtKB/Swiss-Prot for B4GALNT1 Gene
-
Involved in the biosynthesis of gangliosides GM2, GD2 and GA2.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for B4GALNT1 Gene
Genomics for B4GALNT1 Gene
Regulatory Elements for B4GALNT1 Gene
Enhancers for B4GALNT1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around B4GALNT1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for B4GALNT1 Gene
- Chromosome:
- 12
- Start:
- 57,623,410 bp from pter
- End:
- 57,633,355 bp from pter
- Size:
- 9,946 bases
- Orientation:
- Minus strand
Genomic View for B4GALNT1 Gene
Genes around B4GALNT1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q13.3 by Ensembl
- 12q13.3 by Entrez Gene
- 12q13.3 by HGNC
B4GALNT1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for B4GALNT1 Gene
Proteins for B4GALNT1 Gene
-
Protein details for B4GALNT1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q00973-B4GN1_HUMAN
- Recommended name:
- Beta-1,4 N-acetylgalactosaminyltransferase 1
- Protein Accession:
- Q00973
- B4DE26
- Q8N636
Protein attributes for B4GALNT1 Gene
- Size:
- 533 amino acids
- Molecular mass:
- 58882 Da
- Quaternary structure:
-
- Homodimer; disulfide-linked.
Protein Expression for B4GALNT1 Gene
Selected DME Specific Peptides for B4GALNT1 Gene
- Q00973:
-
- GVVNFFLA
- VGFDPRL
- MPFGKGWFAGRNLA
- SQVTTKYVLWVDDDF
Post-translational modifications for B4GALNT1 Gene
Other Protein References for B4GALNT1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
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- Novus Biologicals Antibodies for B4GALNT1
-
Abcam antibodies for B4GALNT1
- Invitrogen Antibodies for B4GALNT1
- antibodies-online Antibodies for B4GALNT1: See all 50
- GeneTex B4GALNT1 antibody for B4GALNT1
-
Santa Cruz Biotechnology (SCBT) Antibodies for B4GALNT1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for B4GALNT1
- Origene Custom Protein Services for B4GALNT1
- antibodies-online Proteins for B4GALNT1: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for B4GALNT1
-
Abcam proteins for B4GALNT1
Assay Products
Domains & Families for B4GALNT1 Gene
Gene Families for B4GALNT1 Gene
Protein Domains for B4GALNT1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for B4GALNT1 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ55323, highly similar to Beta-1,4 N-acetylgalactosaminyltransferase 1 (EC 2.4.1.92) (B4DE26_HUMAN)
- GalNAc-T (B4GN1_HUMAN)
- Beta-1,4-N-acetyl-galactosaminyl transferase 1 isoform a (F8TDK4_HUMAN)
- Beta-1,4-N-acetyl-galactosaminyl transferase 1 isoform b (F8TDK5_HUMAN)
- Beta-1,4-N-acetyl-galactosaminyl transferase 1 isoform c (F8TDK6_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q00973- Family:
-
- Belongs to the glycosyltransferase 2 family.
Function for B4GALNT1 Gene
Molecular function for B4GALNT1 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- UDP-N-acetyl-alpha-D-galactosamine + O-(N-acetyl-alpha-neuraminyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl-(1<->1)-ceramide = UDP + O-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl-(1->4)-O-(N-acetyl-alpha-neuraminyl-(2->3))-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl-(1<->1)-ceramide.
- UniProtKB/Swiss-Prot Function:
- Involved in the biosynthesis of gangliosides GM2, GD2 and GA2.
Enzyme Numbers (IUBMB) for B4GALNT1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003947 | (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity | TAS | -- |
| GO:0008376 | acetylgalactosaminyltransferase activity | IEA | -- |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0016757 | transferase activity, transferring glycosyl groups | IEA | -- |
| GO:0016758 | transferase activity, transferring hexosyl groups | IEA | -- |
Phenotypes for B4GALNT1 Gene
- MGI mutant phenotypes for B4GALNT1:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for B4GALNT1:
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for B4GALNT1 gene
-
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-
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-
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miRNA for B4GALNT1 Gene
- miRTarBase miRNAs that target B4GALNT1
miRNA Products
- Search ViGene Biosciences for B4GALNT1
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for B4GALNT1
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ViGene Biosciences ready-to-package AAV shRNAs for B4GALNT1 gene
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- Sino Biological Human cDNA Clone for B4GALNT1
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for B4GALNT1
-
ViGene Biosciences adenoviral particle packaged cDNA for B4GALNT1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for B4GALNT1 gene
-
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Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for B4GALNT1 Gene
Localization for B4GALNT1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for B4GALNT1 Gene
- Golgi apparatus membrane; Single-pass type II membrane protein.
| Compartment | Confidence |
|---|---|
| golgi apparatus | 5 |
| plasma membrane | 3 |
| extracellular | 2 |
| lysosome | 2 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | -- |
| GO:0005794 | Golgi apparatus | IEA | -- |
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0016020 | membrane | TAS | 1601877 |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for B4GALNT1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism |
.37
|
|
| 2 | Glycosphingolipid biosynthesis - ganglio series | ||
| 3 | Sphingolipid metabolism | ||
Pathways by source for B4GALNT1 Gene
1 BioSystems pathway for B4GALNT1 Gene
4 Reactome pathways for B4GALNT1 Gene
2 KEGG pathways for B4GALNT1 Gene
UniProtKB/Swiss-Prot Q00973-B4GN1_HUMAN
- Pathway: Sphingolipid metabolism.
Interacting Proteins for B4GALNT1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001574 | ganglioside biosynthetic process | IMP | 1601877 |
| GO:0005975 | carbohydrate metabolic process | TAS | 1601877 |
| GO:0006486 | protein glycosylation | IEA | -- |
| GO:0006687 | glycosphingolipid metabolic process | TAS | -- |
| GO:0007283 | spermatogenesis | IEA | -- |
No data available for SIGNOR curated interactions for B4GALNT1 Gene
Drugs & Compounds for B4GALNT1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Uridine-5'-Diphosphate | Experimental | Pharma | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| Ganglioside GA2 (d18:1/12:0) |
|
88506-68-7 |
|
|||
| Ganglioside GA2 (d18:1/16:0) |
|
88506-68-7 |
|
|||
| Ganglioside GA2 (d18:1/20:0) |
|
88506-68-7 |
|
|||
| Ganglioside GA2 (d18:1/24:0) |
|
88506-68-7 |
|
|||
| Ganglioside GA2 (d18:1/24:1(15Z)) |
|
88506-68-7 |
|
Transcripts for B4GALNT1 Gene
mRNA/cDNA for B4GALNT1 Gene
- (9) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (72) Selected AceView cDNA sequences:
- (16) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for B4GALNT1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for B4GALNT1
-
Santa Cruz Biotechnology (SCBT) CRISPR for B4GALNT1
- GenScript: Design CRISPR guide RNA sequences for B4GALNT1
miRNA Products
- Search ViGene Biosciences for B4GALNT1
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for B4GALNT1
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-
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Clone Products
- Sino Biological Human cDNA Clone for B4GALNT1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for B4GALNT1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for B4GALNT1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | · | 14c | ^ | 15a | · | 15b | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: |
| ExUns: | 15c |
|---|---|
| SP1: | |
| SP2: | |
| SP3: | |
| SP4: | |
| SP5: | |
| SP6: | |
| SP7: | |
| SP8: | |
| SP9: | |
| SP10: | |
| SP11: | |
| SP12: |
Expression for B4GALNT1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
- Gut Tube (Gastrointestinal Tract)
-
Yolk Sac (Extraembryonic Tissues)
- Definitive Hematopoietic Stem Cells Definitive Yolk Sac
-
Blood (Cardiovascular System)
- Definitive Hematopoietic Stem Cells Definitive Yolk Sac
-
Epiblast (Early Embryonic Tissues)
- Epiblast Cells Epiblast
- Bone (Muscoskeletal System)
- Adipose (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for B4GALNT1 Gene
This gene is overexpressed in Brain - Cerebellum (x6.0), Brain - Cerebellar Hemisphere (x5.9), Brain - Frontal Cortex (BA9) (x5.0), and Brain - Cortex (x4.9).
This gene is overexpressed in Bone (46.0), Liver (15.0), and Heart (8.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for B4GALNT1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of B4GALNT1 Gene:
B4GALNT1SOURCE GeneReport for Unigene cluster for B4GALNT1 Gene:
Hs.159481Evidence on tissue expression from TISSUES for B4GALNT1 Gene
- Nervous system(4.8)
Phenotype-based relationships between genes and organs from Gene ORGANizer for B4GALNT1 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- nervous
- respiratory
- skeletal muscle
- skeleton
Organs:
Head and neck:
- brain
- cerebellum
- head
Thorax:
- diaphragm
- lung
- rib
- rib cage
Pelvis:
- pelvis
Limb:
- digit
- foot
- hand
- lower limb
- toe
- upper limb
General:
- peripheral nerve
- peripheral nervous system
- spinal column
- spinal cord
- vertebrae
Primer Products
-
OriGene qPCR primer pairs for B4GALNT1
No data available for mRNA Expression by UniProt/SwissProt for B4GALNT1 Gene
Orthologs for B4GALNT1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | B4GALNT1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | GALGT 35 |
|
OneToOne | |
| B4GALNT1 34 |
|
||||
| dog (Canis familiaris) |
Mammalia | B4GALNT1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | B4galnt1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | B4galnt1 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | B4GALNT1 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | B4GALNT1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | b4galnt1 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | MGC53523 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC793635 34 |
|
||
| B4GALNT1 (2 of 2) 35 |
|
OneToMany | |||
| b4galnt1a 35 |
|
OneToMany |
- Species where no ortholog for B4GALNT1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for B4GALNT1 Gene
(1) SIMAP similar genes for B4GALNT1 Gene using alignment to 15 proteins:
Variants for B4GALNT1 Gene
| SNP ID | Clin | Chr 12 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs756710480 | Spastic paraplegia 26, autosomal recessive (SPG26) [MIM:609195] | 57,628,817(+) | GCGGC(A/G)GATAC | nc-transcript-variant, reference, missense | |
| VAR_070236 | Spastic paraplegia 26, autosomal recessive (SPG26) [MIM:609195] | ||||
| rs398122382 | Pathogenic | 57,630,182(-) | GCAGC(C/T)GAAGC | nc-transcript-variant, reference, stop-gained | |
| rs766591558 | Pathogenic | 57,631,075(+) | CAGCT(-/G)GGGAC | nc-transcript-variant, reference, frameshift-variant | |
| rs778572229 | Pathogenic | 57,631,319(+) | GGAGG(-/C)CCCCC | intron-variant, nc-transcript-variant, reference, frameshift-variant |
Residual Variation Intolerance Score:
21.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.48;
77.49% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for B4GALNT1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for B4GALNT1 Gene
Disorders for B4GALNT1 Gene
(2) MalaCards diseases for B4GALNT1 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| spastic paraplegia 26, autosomal recessive |
|
|
| spastic paraplegia 26 |
|
|
Search B4GALNT1 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
B4GN1_HUMAN- Spastic paraplegia 26, autosomal recessive (SPG26) [MIM:609195]: A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. SPG26 is a complicated form characterized by onset in the first 2 decades of life of gait abnormalities due to lower limb spasticity and muscle weakness. Some patients have upper limb involvement. Additional features include intellectual disability, peripheral neuropathy, dysarthria, cerebellar signs, extrapyramidal signs, and cortical atrophy. The disorder is slowly progressive. {ECO:0000269 PubMed:23746551}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for B4GALNT1
No data available for Genatlas for B4GALNT1 Gene
Publications for B4GALNT1 Gene
- Alteration of ganglioside biosynthesis responsible for complex hereditary spastic paraplegia. (PMID: 23746551) Boukhris A. … Stevanin G. (Am. J. Hum. Genet. 2013) 2 3 4 64
- Glycosyltransferase B4GALNT1 and type 1 diabetes in Croatian population: clinical investigation. (PMID: 19318031) Boraska V. … Zemunik T. (Clin. Biochem. 2009) 3 22 46 64
- Expression cloning of beta 1,4 N-acetylgalactosaminyltransferase cDNAs that determine the expression of GM2 and GD2 gangliosides. (PMID: 1601877) Nagata Y. … Furukawa K. (J. Biol. Chem. 1992) 2 3 4 64
- Disulfide bonds of GM2 synthase homodimers. Antiparallel orientation of the catalytic domains. (PMID: 11018043) Li J. … Young W.W. Jr. (J. Biol. Chem. 2000) 3 4 64
- Expression cloning of beta 1,4 N-acetylgalactosaminyltransferase cDNAs that determine the expression of GM2 and GD2 gangliosides. (PMID: 8120069) Nagata Y. … Furukawa K. (J. Biol. Chem. 1994) 3 4 64
Products for B4GALNT1 Gene
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- GenScript: Design CRISPR guide RNA sequences for B4GALNT1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for B4GALNT1
- Sino Biological Human cDNA Clone for B4GALNT1
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for B4GALNT1
- Novus Biologicals proteins and lysates for B4GALNT1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for B4GALNT1
- Abcam proteins for B4GALNT1
- Search for Assays for B4GALNT1 at Abcam
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- antibodies-online Antibodies for B4GALNT1: See all 50
- Search antibodies-online for kits
- antibodies-online Proteins for B4GALNT1: See all 4
- Search antibodies-online for peptides
- GeneTex B4GALNT1 antibody for B4GALNT1
- Search GeneTex for Proteins for B4GALNT1
- ViGene Biosciences adenoviral particle packaged cDNA for B4GALNT1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for B4GALNT1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for B4GALNT1 gene
- Search ViGene Biosciences for B4GALNT1
- Santa Cruz Biotechnology (SCBT) Antibodies for B4GALNT1
- Search Santa Cruz Biotechnology (SCBT) for B4GALNT1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for B4GALNT1
- Horizon Cell Lines for B4GALNT1
- Cyagen custom Knockout/knockin (KOKI) mouse models for B4GALNT1
- VectorBuilder custom plasmid, inducible vectors for B4GALNT1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for B4GALNT1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for B4GALNT1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer