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Aliases for B3GNTL1 Gene

Aliases for B3GNTL1 Gene

  • UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase-Like 1 2 3
  • Beta1,3-N-Acetylglucosaminyltransferase-Like Protein 1 3 4
  • Beta-1,3-N-Acetylglucosaminyltransferase 8 3 4
  • Beta3Gn-T-Like Protein 1 3 4
  • BGnT-Like Protein 1 3 4
  • Beta-1,3-Gn-T8 3 4
  • Beta3Gn-T8 3 4
  • Beta3GnTL1 3 4
  • B3GNT8 3 4
  • BGnT-8 3 4
  • UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 8 3
  • EC 2.4.1.- 4

External Ids for B3GNTL1 Gene

Previous GeneCards Identifiers for B3GNTL1 Gene

  • GC17M081580
  • GC17U900469
  • GC17M078495
  • GC17M080901
  • GC17M076304

Summaries for B3GNTL1 Gene

GeneCards Summary for B3GNTL1 Gene

B3GNTL1 (UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase-Like 1) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and O-linked glycosylation. GO annotations related to this gene include transferase activity, transferring glycosyl groups.

UniProtKB/Swiss-Prot for B3GNTL1 Gene

  • Putative glycosyltransferase.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for B3GNTL1 Gene

Genomics for B3GNTL1 Gene

Regulatory Elements for B3GNTL1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for B3GNTL1 Gene

82,942,149 bp from pter
83,051,845 bp from pter
109,697 bases
Minus strand

Genomic View for B3GNTL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for B3GNTL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for B3GNTL1 Gene

Proteins for B3GNTL1 Gene

  • Protein details for B3GNTL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1
    Protein Accession:
    Secondary Accessions:
    • Q6GV30
    • Q8WUT3

    Protein attributes for B3GNTL1 Gene

    361 amino acids
    Molecular mass:
    40713 Da
    Quaternary structure:
    No Data Available

neXtProt entry for B3GNTL1 Gene

Proteomics data for B3GNTL1 Gene at MOPED

Post-translational modifications for B3GNTL1 Gene

  • Ubiquitination at Lys 271
  • Modification sites at PhosphoSitePlus

Other Protein References for B3GNTL1 Gene

No data available for DME Specific Peptides for B3GNTL1 Gene

Domains & Families for B3GNTL1 Gene

Gene Families for B3GNTL1 Gene

Protein Domains for B3GNTL1 Gene

Suggested Antigen Peptide Sequences for B3GNTL1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the glycosyltransferase 2 family.
  • Belongs to the glycosyltransferase 2 family.
genes like me logo Genes that share domains with B3GNTL1: view

Function for B3GNTL1 Gene

Molecular function for B3GNTL1 Gene

UniProtKB/Swiss-Prot Function:
Putative glycosyltransferase.

Enzyme Numbers (IUBMB) for B3GNTL1 Gene

Gene Ontology (GO) - Molecular Function for B3GNTL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016757 transferase activity, transferring glycosyl groups IBA --
genes like me logo Genes that share ontologies with B3GNTL1: view
genes like me logo Genes that share phenotypes with B3GNTL1: view

Animal Model Products

miRNA for B3GNTL1 Gene

miRTarBase miRNAs that target B3GNTL1

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for B3GNTL1

In Situ Assay Products

Flow Cytometry Products

No data available for Animal Models , Transcription Factor Targets and HOMER Transcription for B3GNTL1 Gene

Localization for B3GNTL1 Gene

Subcellular locations from

Jensen Localization Image for B3GNTL1 Gene COMPARTMENTS Subcellular localization image for B3GNTL1 gene
Compartment Confidence
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for B3GNTL1 Gene

Pathways & Interactions for B3GNTL1 Gene

genes like me logo Genes that share pathways with B3GNTL1: view

Pathways by source for B3GNTL1 Gene

Interacting Proteins for B3GNTL1 Gene

Gene Ontology (GO) - Biological Process for B3GNTL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with B3GNTL1: view

No data available for SIGNOR curated interactions for B3GNTL1 Gene

Drugs & Compounds for B3GNTL1 Gene

No Compound Related Data Available

Transcripts for B3GNTL1 Gene

Unigene Clusters for B3GNTL1 Gene

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for B3GNTL1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for B3GNTL1 Gene

No ASD Table

Relevant External Links for B3GNTL1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for B3GNTL1 Gene

mRNA expression in normal human tissues for B3GNTL1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for B3GNTL1 Gene

This gene is overexpressed in Whole Blood (x7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for B3GNTL1 Gene

SOURCE GeneReport for Unigene cluster for B3GNTL1 Gene Hs.607824

mRNA Expression by UniProt/SwissProt for B3GNTL1 Gene

Tissue specificity: Widely expressed. Highly expressed in adult pancreas. Expressed at moderate level in kidney, spleen, thymus, prostate, testis and ovary. Weakly expressed in small intestine, colon, peripheral blood leukocyte and liver.
genes like me logo Genes that share expression patterns with B3GNTL1: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues and Protein tissue co-expression partners for B3GNTL1 Gene

Orthologs for B3GNTL1 Gene

This gene was present in the common ancestor of animals.

Orthologs for B3GNTL1 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia B3gntl1 35
  • 82.46 (n)
  • 85.76 (a)
B3gntl1 16
B3gntl1 36
  • 83 (a)
(Pan troglodytes)
Mammalia LOC101058185 35
  • 100 (n)
  • 100 (a)
B3GNTL1 36
  • 100 (a)
(Rattus norvegicus)
Mammalia B3gntl1 35
  • 82.46 (n)
  • 86.92 (a)
(Canis familiaris)
Mammalia B3GNTL1 36
  • 79 (a)
(Monodelphis domestica)
Mammalia B3GNTL1 36
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia B3GNTL1 36
  • 74 (a)
(Gallus gallus)
Aves B3GNTL1 35
  • 69.21 (n)
  • 73.61 (a)
B3GNTL1 36
  • 71 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 62 (a)
-- 36
  • 65 (a)
(Danio rerio)
Actinopterygii b3gntl1 35
  • 65.19 (n)
  • 66.27 (a)
b3gntl1 36
  • 61 (a)
(Caenorhabditis elegans)
Secernentea F13G3.6 35
  • 48.73 (n)
  • 42.94 (a)
F13G3.6 36
  • 40 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 52 (a)
Species with no ortholog for B3GNTL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for B3GNTL1 Gene

Gene Tree for B3GNTL1 (if available)
Gene Tree for B3GNTL1 (if available)

Paralogs for B3GNTL1 Gene Pseudogenes for B3GNTL1 Gene

genes like me logo Genes that share paralogs with B3GNTL1: view

No data available for Paralogs for B3GNTL1 Gene

Variants for B3GNTL1 Gene

Sequence variations from dbSNP and Humsavar for B3GNTL1 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs731447 -- 82,986,017(+) TGGGA(G/T)CAAAG intron-variant
rs751409 -- 83,007,502(-) CTCTC(A/T)GTCTT intron-variant, upstream-variant-2KB
rs898097 -- 82,946,434(+) AGATA(C/T)TAAAG intron-variant, downstream-variant-500B
rs898098 -- 82,946,688(+) ATAGA(A/G)TTCAC intron-variant, downstream-variant-500B
rs898099 -- 83,022,192(-) TGACC(A/G)TTTTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for B3GNTL1 Gene

Variant ID Type Subtype PubMed ID
nsv428351 CNV Gain 18775914
esv21913 CNV Gain+Loss 19812545
nsv909246 CNV Loss 21882294
dgv3366n71 CNV Loss 21882294
nsv909254 CNV Gain 21882294
nsv909255 CNV Gain 21882294
dgv3367n71 CNV Gain 21882294
nsv909257 CNV Gain 21882294
nsv909259 CNV Gain 21882294
dgv3368n71 CNV Loss 21882294
nsv529032 CNV Loss 19592680
nsv909262 CNV Loss 21882294
dgv3369n71 CNV Loss 21882294
esv2716566 CNV Deletion 23290073
esv2716567 CNV Deletion 23290073
esv2678985 CNV Deletion 23128226
esv2716568 CNV Deletion 23290073
esv1364448 CNV Insertion 17803354
esv2656462 CNV Deletion 23128226
esv1522450 CNV Insertion 17803354
esv1980223 CNV Deletion 18987734
esv2716569 CNV Deletion 23290073
dgv482e201 CNV Deletion 23290073
esv1789492 CNV Insertion 17803354
esv2741019 CNV Deletion 23290073
nsv112402 CNV Loss 16902084
esv2716570 CNV Deletion 23290073
esv2512397 CNV Deletion 19546169
esv2716571 CNV Deletion 23290073
nsv512511 CNV Loss 21212237
esv2665906 CNV Deletion 23128226
esv2716572 CNV Deletion 23290073
esv1063912 CNV Deletion 17803354
esv1207311 CNV Deletion 17803354
esv1777160 CNV Deletion 17803354
esv1317334 CNV Deletion 17803354
esv2716574 CNV Deletion 23290073
esv1627319 CNV Deletion 17803354
dgv483e201 CNV Deletion 23290073
esv2716576 CNV Deletion 23290073
esv2716577 CNV Deletion 23290073
esv2716578 CNV Deletion 23290073
dgv484e201 CNV Deletion 23290073
esv2716582 CNV Deletion 23290073
esv2716583 CNV Deletion 23290073
esv1073119 CNV Insertion 17803354
esv1055866 CNV Insertion 17803354
esv2716586 CNV Deletion 23290073
esv2337820 CNV Deletion 18987734
esv2716587 CNV Deletion 23290073
esv2670486 CNV Deletion 23128226
esv1040276 CNV Deletion 17803354
esv2716588 CNV Deletion 23290073
esv2716589 CNV Deletion 23290073
esv2716590 CNV Deletion 23290073
nsv909266 CNV Loss 21882294
nsv817777 CNV Loss 17921354
esv2476328 CNV Deletion 19546169
nsv111962 CNV Loss 16902084
esv5160 CNV Deletion 18987735
esv998309 CNV Deletion 20482838
esv1288528 CNV Deletion 17803354
esv2716591 CNV Deletion 23290073
nsv112440 CNV Loss 16902084
esv2668880 CNV Deletion 23128226
nsv820466 CNV Deletion 20802225
esv1508603 CNV Deletion 17803354
esv2716592 CNV Deletion 23290073
esv2567730 CNV Insertion 19546169
esv2716593 CNV Deletion 23290073
esv2716594 CNV Deletion 23290073
esv1787320 CNV Insertion 17803354
esv2716595 CNV Deletion 23290073
nsv909268 CNV Gain 21882294
nsv828147 CNV Loss 20364138
esv2716597 CNV Deletion 23290073
esv2716598 CNV Deletion 23290073
dgv3372n71 CNV Loss 21882294
dgv3373n71 CNV Loss 21882294
nsv828148 CNV Loss 20364138
esv2716599 CNV Deletion 23290073
esv2658570 CNV Deletion 23128226
esv2716600 CNV Deletion 23290073
esv2663386 CNV Deletion 23128226
nsv828149 CNV Gain 20364138

Variation tolerance for B3GNTL1 Gene

Residual Variation Intolerance Score: 88.17% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.25; 88.12% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for B3GNTL1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for B3GNTL1 Gene

Disorders for B3GNTL1 Gene

Relevant External Links for B3GNTL1

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with B3GNTL1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for B3GNTL1 Gene

Publications for B3GNTL1 Gene

  1. A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. (PMID: 19875614) Paterson A.D. … Bull S.B. (Diabetes 2010) 67
  2. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 67
  3. Characterization of a cDNA encoding a protein with limited similarity to beta1, 3-N-acetylglucosaminyltransferase. (PMID: 15560372) Zheng H. … Mao Y. (Mol. Biol. Rep. 2004) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67

Products for B3GNTL1 Gene

Sources for B3GNTL1 Gene

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