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Aliases for B3GNT9 Gene

Aliases for B3GNT9 Gene

  • UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 9 2 3 5
  • Beta-1,3-N-Acetylglucosaminyltransferase 9 3 4
  • Beta-1,3-Gn-T9 3 4
  • Beta3Gn-T9 3 4
  • BGnT-9 3 4
  • Beta-1,3-Galactosyltransferase-Related Protein 3
  • EC 2.4.1.- 4

External Ids for B3GNT9 Gene

Previous GeneCards Identifiers for B3GNT9 Gene

  • GC16M065740
  • GC16M067182
  • GC16M053055

Summaries for B3GNT9 Gene

GeneCards Summary for B3GNT9 Gene

B3GNT9 (UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 9) is a Protein Coding gene. Among its related pathways are O-linked glycosylation and Transport to the Golgi and subsequent modification. GO annotations related to this gene include transferase activity, transferring glycosyl groups and galactosyltransferase activity. An important paralog of this gene is B3GNT5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for B3GNT9 Gene

Genomics for B3GNT9 Gene

Regulatory Elements for B3GNT9 Gene

Promoters for B3GNT9 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around B3GNT9 on UCSC Golden Path with GeneCards custom track

Genomic Location for B3GNT9 Gene

Chromosome:
16
Start:
67,148,102 bp from pter
End:
67,151,214 bp from pter
Size:
3,113 bases
Orientation:
Minus strand

Genomic View for B3GNT9 Gene

Genes around B3GNT9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
B3GNT9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for B3GNT9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for B3GNT9 Gene

Proteins for B3GNT9 Gene

  • Protein details for B3GNT9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UX72-B3GN9_HUMAN
    Recommended name:
    UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
    Protein Accession:
    Q6UX72
    Secondary Accessions:
    • Q96EK0

    Protein attributes for B3GNT9 Gene

    Size:
    402 amino acids
    Molecular mass:
    43751 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BC012191; Type=Frameshift; Positions=81; Evidence={ECO:0000305};

neXtProt entry for B3GNT9 Gene

Proteomics data for B3GNT9 Gene at MOPED

Post-translational modifications for B3GNT9 Gene

  • Glycosylation at Thr 329
  • Modification sites at PhosphoSitePlus

Other Protein References for B3GNT9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for B3GNT9 Gene

Domains & Families for B3GNT9 Gene

Gene Families for B3GNT9 Gene

Protein Domains for B3GNT9 Gene

Suggested Antigen Peptide Sequences for B3GNT9 Gene

Graphical View of Domain Structure for InterPro Entry

Q6UX72

UniProtKB/Swiss-Prot:

B3GN9_HUMAN :
  • Belongs to the glycosyltransferase 31 family.
Family:
  • Belongs to the glycosyltransferase 31 family.
genes like me logo Genes that share domains with B3GNT9: view

Function for B3GNT9 Gene

Enzyme Numbers (IUBMB) for B3GNT9 Gene

genes like me logo Genes that share phenotypes with B3GNT9: view

Animal Model Products

No data available for Molecular function , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for B3GNT9 Gene

Localization for B3GNT9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for B3GNT9 Gene

Golgi apparatus membrane; Single-pass type II membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for B3GNT9 Gene COMPARTMENTS Subcellular localization image for B3GNT9 gene
Compartment Confidence
golgi apparatus 4
endoplasmic reticulum 1
extracellular 1
lysosome 1
mitochondrion 1
peroxisome 1
vacuole 1

Gene Ontology (GO) - Cellular Components for B3GNT9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with B3GNT9: view

Pathways & Interactions for B3GNT9 Gene

genes like me logo Genes that share pathways with B3GNT9: view

Interacting Proteins for B3GNT9 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000400157%0d%0a9606.ENSP00000230321%0d%0a
Selected Interacting proteins: Q6UX72-B3GN9_HUMAN ENSP00000400157 for B3GNT9 Gene via I2D STRING

Gene Ontology (GO) - Biological Process for B3GNT9 Gene

None

No data available for SIGNOR curated interactions for B3GNT9 Gene

Drugs & Compounds for B3GNT9 Gene

No Compound Related Data Available

Transcripts for B3GNT9 Gene

mRNA/cDNA for B3GNT9 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(141) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for B3GNT9 Gene

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for B3GNT9 Gene

No ASD Table

Relevant External Links for B3GNT9 Gene

GeneLoc Exon Structure for
B3GNT9
ECgene alternative splicing isoforms for
B3GNT9

Expression for B3GNT9 Gene

mRNA expression in normal human tissues for B3GNT9 Gene

Protein differential expression in normal tissues from HIPED for B3GNT9 Gene

This gene is overexpressed in Serum (64.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for B3GNT9 Gene



SOURCE GeneReport for Unigene cluster for B3GNT9 Gene Hs.744158

genes like me logo Genes that share expression patterns with B3GNT9: view

Protein tissue co-expression partners for B3GNT9 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for B3GNT9 Gene

Orthologs for B3GNT9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for B3GNT9 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia B3GNT9 35
  • 86.36 (n)
  • 88.5 (a)
dog
(Canis familiaris)
Mammalia B3GNT9 35
  • 85.17 (n)
  • 87.25 (a)
B3GNT9 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia B3gnt9 35
  • 80.14 (n)
  • 85.18 (a)
B3gnt9 16
B3gnt9 36
  • 83 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia B3gnt9 35
  • 80.2 (n)
  • 86.83 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 35 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia B3GNT9 36
  • 62 (a)
OneToOne
chicken
(Gallus gallus)
Aves B3GNT9 35
  • 62.72 (n)
  • 63.82 (a)
B3GNT9 36
  • 51 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia B3GNT9 36
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia b3gnt9 35
  • 54.12 (n)
  • 56.76 (a)
zebrafish
(Danio rerio)
Actinopterygii b3gnt9 35
  • 56.4 (n)
  • 55.23 (a)
b3gnt9 36
  • 46 (a)
OneToOne
Species with no ortholog for B3GNT9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for B3GNT9 Gene

ENSEMBL:
Gene Tree for B3GNT9 (if available)
TreeFam:
Gene Tree for B3GNT9 (if available)

Paralogs for B3GNT9 Gene

(6) SIMAP similar genes for B3GNT9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with B3GNT9: view

Variants for B3GNT9 Gene

Sequence variations from dbSNP and Humsavar for B3GNT9 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs5817615 -- 67,151,797(+) AGGCC(-/T)TGTGC upstream-variant-2KB
rs11555267 -- 67,150,309(-) TTACC(A/C)GACGC reference, synonymous-codon
rs34729812 -- 67,149,172(+) TGTGG(-/T)AGACA utr-variant-3-prime
rs34464219 -- 67,149,420(+) AAGCA(-/G)GGGGT reference, frameshift-variant
rs35421889 -- 67,149,510(+) CCGCA(-/G)GCGCT reference, frameshift-variant

Structural Variations from Database of Genomic Variants (DGV) for B3GNT9 Gene

Variant ID Type Subtype PubMed ID
dgv2885n71 CNV Loss 21882294
nsv906794 CNV Loss 21882294
dgv2886n71 CNV Loss 21882294
dgv2887n71 CNV Loss 21882294
dgv2888n71 CNV Loss 21882294
nsv524363 CNV Loss 19592680
nsv827707 CNV Loss 20364138

Variation tolerance for B3GNT9 Gene

Residual Variation Intolerance Score: 32.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.87; 18.07% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for B3GNT9 Gene

HapMap Linkage Disequilibrium report
B3GNT9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for B3GNT9 Gene

Disorders for B3GNT9 Gene

Relevant External Links for B3GNT9

Genetic Association Database (GAD)
B3GNT9
Human Genome Epidemiology (HuGE) Navigator
B3GNT9
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
B3GNT9

No disorders were found for B3GNT9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for B3GNT9 Gene

Publications for B3GNT9 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4 67
  2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3
  3. An empirical framework for binary interactome mapping. (PMID: 19060904) Venkatesan K. … Vidal M. (Nat. Methods 2009) 3
  4. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3
  5. Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. (PMID: 17110338) Wang X. … Balch W.E. (Cell 2006) 3

Products for B3GNT9 Gene

Sources for B3GNT9 Gene

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