Free for academic non-profit institutions. Other users need a Commercial license

Aliases for B3GNT9 Gene

Aliases for B3GNT9 Gene

  • UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 9 2 3 5
  • Beta-1,3-N-Acetylglucosaminyltransferase 9 3 4
  • Beta-1,3-Gn-T9 3 4
  • Beta3Gn-T9 3 4
  • BGnT-9 3 4
  • Beta-1,3-Galactosyltransferase-Related Protein 3
  • EC 2.4.1.- 4

External Ids for B3GNT9 Gene

Previous GeneCards Identifiers for B3GNT9 Gene

  • GC16M065740
  • GC16M067182
  • GC16M053055

Summaries for B3GNT9 Gene

GeneCards Summary for B3GNT9 Gene

B3GNT9 (UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 9) is a Protein Coding gene. Among its related pathways are O-linked glycosylation and Metabolism of proteins. GO annotations related to this gene include transferase activity, transferring glycosyl groups and galactosyltransferase activity. An important paralog of this gene is B3GNT7.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for B3GNT9 Gene

Genomics for B3GNT9 Gene

Regulatory Elements for B3GNT9 Gene

Enhancers for B3GNT9 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G066977 1.5 Ensembl ENCODE dbSUPER 11.2 +173.4 173414 0.4 HDGF WRNIP1 ARID4B SIN3A ZNF2 ZNF48 SLC30A9 GLIS2 ZNF143 DEK CES2 ELMO3 CBFB B3GNT9 FBXL8 TRADD HSF4 C16orf70 RRAD CDH16
GH16G067027 1.4 ENCODE dbSUPER 11.1 +121.7 121723 3.0 HDGF MLX CREB3L1 ARNT AGO1 ZFP64 WRNIP1 ARID4B SIN3A DMAP1 C16orf70 B3GNT9 ELMO3 ENSG00000260465 ATP6V0D1 RIPOR1 CBFB GC16P067102
GH16G066960 1.2 Ensembl ENCODE 11.3 +190.1 190094 1.0 HDGF PKNOX1 ARNT SIN3A ARID4B ZNF2 ZNF48 ZNF143 DEK MIER2 FBXL8 TRADD HSF4 CES2 RRAD CDH16 FAM96B B3GNT9 CBFB ELMO3
GH16G066871 1.6 FANTOM5 ENCODE 7.3 +277.4 277374 5.1 CREB3L1 MLX FEZF1 DMAP1 SLC30A9 ZNF143 ZNF263 SP3 NFYC TBX21 E2F4 CES2 CA7 PLEKHG4 ZDHHC1 KIAA0895L CENPT ENSG00000260465 FAM96B FBXL8
GH16G066879 1.1 ENCODE 10.1 +270.4 270442 2.0 PKNOX1 MLX CREB3L1 ARNT ZFP64 ARID4B SIN3A DMAP1 SLC30A9 ZNF416 CES2 ENSG00000260465 CDH16 RRAD ZDHHC1 FAM96B CENPT CA7 B3GNT9 THAP11
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around B3GNT9 on UCSC Golden Path with GeneCards custom track

Promoters for B3GNT9 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000087067 514 1001 PKNOX1 AGO1 ARID4B SIN3A DMAP1 ZBTB7B SLC30A9 ZNF143 ZNF207 KLF13

Genomic Location for B3GNT9 Gene

Chromosome:
16
Start:
67,148,102 bp from pter
End:
67,151,214 bp from pter
Size:
3,113 bases
Orientation:
Minus strand

Genomic View for B3GNT9 Gene

Genes around B3GNT9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
B3GNT9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for B3GNT9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for B3GNT9 Gene

Proteins for B3GNT9 Gene

  • Protein details for B3GNT9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UX72-B3GN9_HUMAN
    Recommended name:
    UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
    Protein Accession:
    Q6UX72
    Secondary Accessions:
    • Q96EK0

    Protein attributes for B3GNT9 Gene

    Size:
    402 amino acids
    Molecular mass:
    43751 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BC012191; Type=Frameshift; Positions=81; Evidence={ECO:0000305};

neXtProt entry for B3GNT9 Gene

Post-translational modifications for B3GNT9 Gene

  • Glycosylation at Thr329
  • Modification sites at PhosphoSitePlus

Other Protein References for B3GNT9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for B3GNT9 Gene

Domains & Families for B3GNT9 Gene

Gene Families for B3GNT9 Gene

Protein Domains for B3GNT9 Gene

Suggested Antigen Peptide Sequences for B3GNT9 Gene

Graphical View of Domain Structure for InterPro Entry

Q6UX72

UniProtKB/Swiss-Prot:

B3GN9_HUMAN :
  • Belongs to the glycosyltransferase 31 family.
Family:
  • Belongs to the glycosyltransferase 31 family.
genes like me logo Genes that share domains with B3GNT9: view

Function for B3GNT9 Gene

Enzyme Numbers (IUBMB) for B3GNT9 Gene

Gene Ontology (GO) - Molecular Function for B3GNT9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008378 galactosyltransferase activity IEA --
GO:0016740 transferase activity IEA --
GO:0016757 transferase activity, transferring glycosyl groups IEA --
genes like me logo Genes that share ontologies with B3GNT9: view
genes like me logo Genes that share phenotypes with B3GNT9: view

Animal Model Products

  • Taconic Biosciences Mouse Models for B3GNT9

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for B3GNT9 Gene

Localization for B3GNT9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for B3GNT9 Gene

Golgi apparatus membrane; Single-pass type II membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for B3GNT9 gene
Compartment Confidence
golgi apparatus 5
nucleus 4
extracellular 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1
lysosome 1

Gene Ontology (GO) - Cellular Components for B3GNT9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA --
GO:0001650 fibrillar center IDA --
GO:0005794 Golgi apparatus IDA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with B3GNT9: view

Pathways & Interactions for B3GNT9 Gene

genes like me logo Genes that share pathways with B3GNT9: view

Interacting Proteins for B3GNT9 Gene

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000400157%0d%0a9606.ENSP00000416753%0d%0a9606.ENSP00000406861%0d%0a9606.ENSP00000441929%0d%0a9606.ENSP00000302021%0d%0a9606.ENSP00000324834%0d%0a
Selected Interacting proteins: Q6UX72-B3GN9_HUMAN ENSP00000400157 for B3GNT9 Gene via IID STRING

Gene Ontology (GO) - Biological Process for B3GNT9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006486 protein glycosylation IEA --
genes like me logo Genes that share ontologies with B3GNT9: view

No data available for SIGNOR curated interactions for B3GNT9 Gene

Transcripts for B3GNT9 Gene

mRNA/cDNA for B3GNT9 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(141) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for B3GNT9 Gene

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for B3GNT9 Gene

No ASD Table

Relevant External Links for B3GNT9 Gene

GeneLoc Exon Structure for
B3GNT9
ECgene alternative splicing isoforms for
B3GNT9

Expression for B3GNT9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for B3GNT9 Gene

Protein differential expression in normal tissues from HIPED for B3GNT9 Gene

This gene is overexpressed in Serum (64.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for B3GNT9 Gene



Protein tissue co-expression partners for B3GNT9 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of B3GNT9 Gene:

B3GNT9

SOURCE GeneReport for Unigene cluster for B3GNT9 Gene:

Hs.744158

Evidence on tissue expression from TISSUES for B3GNT9 Gene

  • Lung(4.1)
genes like me logo Genes that share expression patterns with B3GNT9: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for B3GNT9 Gene

Orthologs for B3GNT9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for B3GNT9 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia B3GNT9 34
  • 86.36 (n)
dog
(Canis familiaris)
Mammalia B3GNT9 34 35
  • 85.17 (n)
rat
(Rattus norvegicus)
Mammalia B3gnt9 34
  • 80.2 (n)
mouse
(Mus musculus)
Mammalia B3gnt9 34 16 35
  • 80.14 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia B3GNT9 35
  • 62 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 35 (a)
ManyToMany
chicken
(Gallus gallus)
Aves B3GNT9 34 35
  • 62.72 (n)
lizard
(Anolis carolinensis)
Reptilia B3GNT9 35
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia b3gnt9 34
  • 54.12 (n)
zebrafish
(Danio rerio)
Actinopterygii b3gnt9 34 35
  • 56.4 (n)
Species where no ortholog for B3GNT9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for B3GNT9 Gene

ENSEMBL:
Gene Tree for B3GNT9 (if available)
TreeFam:
Gene Tree for B3GNT9 (if available)

Paralogs for B3GNT9 Gene

(6) SIMAP similar genes for B3GNT9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with B3GNT9: view

Variants for B3GNT9 Gene

Sequence variations from dbSNP and Humsavar for B3GNT9 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000042696 -- 67,151,388(+) CTGTC(-/T)TCTTA upstream-variant-2KB
rs1000114051 -- 67,152,868(+) AACTG(A/T)GTCCA upstream-variant-2KB
rs1000531733 -- 67,148,098(+) AGAAA(A/G)ATGTA downstream-variant-500B, utr-variant-3-prime
rs1000562328 -- 67,151,202(+) TAGCT(C/G)CCCCA upstream-variant-2KB
rs1000963083 -- 67,148,559(+) TTGGT(A/T)TTTTG intron-variant, downstream-variant-500B, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for B3GNT9 Gene

Variant ID Type Subtype PubMed ID
nsv524363 CNV loss 19592680
nsv827707 CNV loss 20364138
nsv952044 CNV deletion 24416366

Variation tolerance for B3GNT9 Gene

Residual Variation Intolerance Score: 32.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.87; 18.07% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for B3GNT9 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
B3GNT9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for B3GNT9 Gene

Disorders for B3GNT9 Gene

Relevant External Links for B3GNT9

Genetic Association Database (GAD)
B3GNT9
Human Genome Epidemiology (HuGE) Navigator
B3GNT9
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
B3GNT9

No disorders were found for B3GNT9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for B3GNT9 Gene

Publications for B3GNT9 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4 64
  2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 46 64
  3. An empirical framework for binary interactome mapping. (PMID: 19060904) Venkatesan K. … Vidal M. (Nat. Methods 2009) 3 64
  4. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3 64
  5. Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. (PMID: 17110338) Wang X. … Balch W.E. (Cell 2006) 3 64

Products for B3GNT9 Gene

Sources for B3GNT9 Gene

Content
Loading form....