Aliases for B3GNT6 Gene
Aliases for B3GNT6 Gene
External Ids for B3GNT6 Gene
- HGNC: 24141
- Entrez Gene: 192134
- Ensembl: ENSG00000198488
- OMIM: 615315
- UniProtKB: Q6ZMB0
Previous GeneCards Identifiers for B3GNT6 Gene
- GC11M068646
- GC11M067794
- GC11M066362
- GC11M065889
- GC11M065890
- GC11M065869
- GC11P076425
- GC11P076745
- GC11P073043
Summaries for B3GNT6 Gene
-
The protein encoded by this gene is a beta-1,3-N-acetylglucosaminyltransferase that adds an N-acetylglucosamine moiety to N-acetylgalactosamine-modified serine or threonine. The encoded enzyme is responsible for creating the core 3 structure of O-glycans, which are important components of mucin-type glycoproteins. [provided by RefSeq, Dec 2016]
GeneCards Summary for B3GNT6 Gene
B3GNT6 (UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 6) is a Protein Coding gene. Among its related pathways are O-linked glycosylation and Metabolism of proteins. GO annotations related to this gene include galactosyltransferase activity and beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity. An important paralog of this gene is B3GNT3.
UniProtKB/Swiss-Prot for B3GNT6 Gene
-
Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for B3GNT6 Gene
Genomics for B3GNT6 Gene
Regulatory Elements for B3GNT6 Gene
Enhancers for B3GNT6 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH11G077029 | 1.1 | ENCODE dbSUPER | 9.2 | -4.3 | -4253 | 1.2 | LEF1 ETV1 ZNF175 BACH1 CTBP1 ZNF316 GATA2 NCOR1 FOS NFE2 | B3GNT6 ENSG00000254988 |
| GH11G076823 | 1.9 | FANTOM5 Ensembl ENCODE dbSUPER | 5.2 | -209.6 | -209551 | 3.1 | HDGF PKNOX1 ATF1 CREB3L1 ARNT TCF12 ZNF766 GATA2 ZNF548 FOS | ACER3 B3GNT6 GDPD4 ENSG00000261578 |
| GH11G077019 | 1.1 | ENCODE dbSUPER | 8.1 | -13.9 | -13868 | 1.7 | ELF3 PKNOX1 FOXA2 GATA2 EGR1 FOS EGR2 USF2 ZNF217 MBD2 | MYO7A ENSG00000254632 GDPD4 B3GNT6 ACER3 ENSG00000254988 |
| GH11G076806 | 1.4 | Ensembl ENCODE dbSUPER | 5.8 | -226.8 | -226789 | 1.1 | HDAC1 YBX3 HDGF ATF1 CBX3 RB1 SIN3A YBX1 NFXL1 ZNF48 | ACER3 LOC101928837 TSKU ENSG00000255363 B3GNT6 ENSG00000261578 |
| GH11G077026 | 0.9 | ENCODE dbSUPER | 8.2 | -6.9 | -6912 | 1.2 | BCOR SMARCA5 SMARCA4 HDAC2 ADNP ZMYM3 KDM1A ZKSCAN1 | B3GNT6 ENSG00000254988 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around B3GNT6 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the B3GNT6 gene promoter:
Regulatory Element Products
Genomic Location for B3GNT6 Gene
- Chromosome:
- 11
- Start:
- 77,034,341 bp from pter
- End:
- 77,041,973 bp from pter
- Size:
- 7,633 bases
- Orientation:
- Plus strand
Genomic View for B3GNT6 Gene
Genes around B3GNT6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q13.5 by Ensembl
- 11q13.5 by Entrez Gene
- 11q13.5 by HGNC
B3GNT6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for B3GNT6 Gene
Proteins for B3GNT6 Gene
-
Protein details for B3GNT6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6ZMB0-B3GN6_HUMAN
- Recommended name:
- Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase
- Protein Accession:
- Q6ZMB0
- E9PKS1
- Q6ZSC5
- Q8TAZ4
- Q8TDX1
Protein attributes for B3GNT6 Gene
- Size:
- 384 amino acids
- Molecular mass:
- 42748 Da
- Quaternary structure:
- No Data Available
- Miscellaneous:
-
- Injection into nude mice significantly suppress lung metastasis, indicating that the core structures of O-glycans are profoundly involved in the metastatic capacity of cancer cells.
Protein Expression for B3GNT6 Gene
Post-translational modifications for B3GNT6 Gene
Other Protein References for B3GNT6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for B3GNT6
- Novus Biologicals Antibodies for B3GNT6
-
Abcam antibodies for B3GNT6
- Invitrogen Antibodies for B3GNT6
- antibodies-online Antibodies for B3GNT6: See all 23
- Search GeneTex for Antibodies for B3GNT6
Protein Products
- R&D Systems Proteins and Enzymes for B3GNT6 ("Beta-1,3-N-Acetylglucosaminyltransferase 6/B3GNT6")
-
OriGene Purified Proteins for B3GNT6
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- Sino Biological Cell Lysates for B3GNT6
- antibodies-online Proteins for B3GNT6: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for B3GNT6
-
Abcam proteins for B3GNT6
Assay Products
No data available for DME Specific Peptides for B3GNT6 Gene
Domains & Families for B3GNT6 Gene
Gene Families for B3GNT6 Gene
Protein Domains for B3GNT6 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for B3GNT6 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q6ZMB0- Family:
-
- Belongs to the glycosyltransferase 31 family.
Function for B3GNT6 Gene
Molecular function for B3GNT6 Gene
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: KM=3.3 mM for GalNAc-alpha-Bn {ECO:0000269 PubMed:7655172}; Vmax=4.5 nmol/h/mg enzyme with GalNAc-alpha-Bn as substrate {ECO:0000269 PubMed:7655172};
- UniProtKB/Swiss-Prot CatalyticActivity:
- UDP-N-acetyl-alpha-D-glucosamine + O(3)-(N-acetyl-alpha-D-galactosaminyl)-L-threonyl/L-seryl-[protein] = UDP + O(3)-(N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl)-L-threonyl/L-seryl-[protein].
- UniProtKB/Swiss-Prot Function:
- Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs.
- UniProtKB/Swiss-Prot Induction:
- Down-regulated in gastric and colorectal carcinomas, suggesting that it may be used as a marker for distinguishing between benign adenomas and premalignant lesions (at protein level).
Enzyme Numbers (IUBMB) for B3GNT6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008378 | galactosyltransferase activity | IDA | 11821425 |
| GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity | TAS | -- |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0016757 | transferase activity, transferring glycosyl groups | IEA | -- |
| GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity | NAS | 11821425 |
Phenotypes for B3GNT6 Gene
- MGI mutant phenotypes for B3GNT6:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for B3GNT6:
Animal Models for B3GNT6 Gene
- MGI Knock Outs for B3GNT6:
-
- B3gnt6 tm1Lx
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for B3GNT6 gene
-
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- Search ViGene Biosciences for B3GNT6
CRISPR Products
-
OriGene CRISPR knockouts for B3GNT6
-
Santa Cruz Biotechnology (SCBT) CRISPR for B3GNT6
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miRNA for B3GNT6 Gene
- miRTarBase miRNAs that target B3GNT6
miRNA Products
- Search ViGene Biosciences for B3GNT6
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for B3GNT6
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Clone Products
-
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for B3GNT6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for B3GNT6
-
ViGene Biosciences adenoviral particle packaged cDNA for B3GNT6 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for B3GNT6 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for B3GNT6 gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for B3GNT6 Gene
Localization for B3GNT6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for B3GNT6 Gene
- Golgi apparatus membrane; Single-pass type II membrane protein.
| Compartment | Confidence |
|---|---|
| golgi apparatus | 5 |
| extracellular | 2 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | -- |
| GO:0005794 | Golgi apparatus | IEA | -- |
| GO:0016020 | membrane | NAS | 11821425 |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for B3GNT6 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism of proteins | ||
| 2 | O-linked glycosylation | ||
| 3 | Metabolism | ||
| 4 | Mucin type O-glycan biosynthesis | ||
Pathways by source for B3GNT6 Gene
4 Reactome pathways for B3GNT6 Gene
2 KEGG pathways for B3GNT6 Gene
UniProtKB/Swiss-Prot Q6ZMB0-B3GN6_HUMAN
- Pathway: Protein modification; protein glycosylation.
Interacting Proteins for B3GNT6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006486 | protein glycosylation | IEA | -- |
| GO:0009101 | glycoprotein biosynthetic process | NAS | 11821425 |
| GO:0016266 | O-glycan processing | TAS | -- |
| GO:0016269 | O-glycan processing, core 3 | NAS | 11821425 |
No data available for SIGNOR curated interactions for B3GNT6 Gene
Transcripts for B3GNT6 Gene
mRNA/cDNA for B3GNT6 Gene
- (1) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (19) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for B3GNT6 Gene
CRISPR Products
-
OriGene CRISPR knockouts for B3GNT6
-
Santa Cruz Biotechnology (SCBT) CRISPR for B3GNT6
- GenScript: Design CRISPR guide RNA sequences for B3GNT6
miRNA Products
- Search ViGene Biosciences for B3GNT6
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for B3GNT6
- Browse OriGene Inhibitory RNA Products For B3GNT6
-
ViGene Biosciences ready-to-package AAV shRNAs for B3GNT6 gene
Clone Products
-
OriGene ORF clones in human for B3GNT6
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for B3GNT6
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for B3GNT6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for B3GNT6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for B3GNT6 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Inner Cell Mass (Early Embryonic Tissues)
- Inner Cell Mass Cells Inner Cell Mass
mRNA differential expression in normal tissues according to GTEx for B3GNT6 Gene
This gene is overexpressed in Colon - Transverse (x22.1), Stomach (x11.4), Small Intestine - Terminal Ileum (x7.0), and Esophagus - Mucosa (x6.8).
This gene is overexpressed in Colon (50.4) and Testis (18.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for B3GNT6 Gene
NURSA nuclear receptor signaling pathways regulating expression of B3GNT6 Gene:
B3GNT6SOURCE GeneReport for Unigene cluster for B3GNT6 Gene:
Hs.352622mRNA Expression by UniProt/SwissProt for B3GNT6 Gene:
Q6ZMB0-B3GN6_HUMAN
Tissue specificity:
Present in stomach and colon (at protein level). Restricted in the stomach, colon and small intestine, where core 3 structure is present.
Evidence on tissue expression from TISSUES for B3GNT6 Gene
- Intestine(4.2)
- Pancreas(4)
- Nervous system(2.4)
Primer Products
-
OriGene qPCR primer pairs for B3GNT6
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for B3GNT6 Gene
Orthologs for B3GNT6 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | B3GNT6 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | B3GNT6 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | B3GNT6 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | B3gnt6 34 |
|
||
| mouse (Mus musculus) |
Mammalia | B3gnt6 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
ManyToMany | |
| chicken (Gallus gallus) |
Aves | B3GNT6 34 |
|
||
| -- 35 |
|
OneToMany | |||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | b3gnt3 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | b3gnt3 35 |
|
ManyToMany | |
| si:ch211-126g16.10 35 |
|
ManyToMany | |||
| si:ch211-126g16.11 35 |
|
ManyToMany | |||
| zgc:86586 35 |
|
ManyToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | BEST:GH04269 36 |
|
|
- Species where no ortholog for B3GNT6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for B3GNT6 Gene
Paralogs for B3GNT6 Gene
(9) SIMAP similar genes for B3GNT6 Gene using alignment to 3 proteins:
Variants for B3GNT6 Gene
| SNP ID | Clin | Chr 11 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs781821239 | Likely pathogenic | 77,040,103(+) | GGCGA(C/G)GTGCT | reference, missense | |
| rs1000965618 | -- | 77,040,762(+) | AAGGC(A/G)GCTTT | utr-variant-3-prime | |
| rs1000981132 | -- | 77,035,139(+) | CTAGG(C/T)AGAGT | intron-variant | |
| rs1000996913 | -- | 77,040,992(+) | AGACT(A/G)TCTCT | utr-variant-3-prime | |
| rs1001329034 | -- | 77,042,079(+) | AAAAT(C/T)AAGGA | downstream-variant-500B |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1040996 | CNV | gain | 25217958 |
| nsv1138053 | CNV | deletion | 24896259 |
| nsv397 | CNV | insertion | 18451855 |
Residual Variation Intolerance Score:
93.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
11.05;
92.15% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for B3GNT6 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- B3GNT6
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for B3GNT6 Gene
Disorders for B3GNT6 Gene
Relevant External Links for B3GNT6
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- B3GNT6
No disorders were found for B3GNT6 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for B3GNT6 Gene
Publications for B3GNT6 Gene
- Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc- peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans. (PMID: 11821425) Iwai T. … Narimatsu H. (J. Biol. Chem. 2002) 2 3 4 64
- Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells. (PMID: 15755813) Iwai T. … Narimatsu H. (Proc. Natl. Acad. Sci. U.S.A. 2005) 3 4 64
- A Panel of Recombinant Mucins Carrying a Repertoire of Sialylated O-Glycans Based on Different Core Chains for Studies of Glycan Binding Proteins. (PMID: 26274979) Cherian R.M. … Holgersson J. (Biomolecules 2015) 3 64
- An integrative framework identifies alternative splicing events in colorectal cancer development. (PMID: 24189147) Bisognin A. … Mandruzzato S. (Mol Oncol 2014) 3 64
- Core3 O-glycan synthase suppresses tumor formation and metastasis of prostate carcinoma PC3 and LNCaP cells through down-regulation of alpha2beta1 integrin complex. (PMID: 19395705) Lee S.H. … Fukuda M. (J. Biol. Chem. 2009) 3 64
Products for B3GNT6 Gene
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- Novus Biologicals Antibodies for B3GNT6
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- Abcam antibodies for B3GNT6
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- antibodies-online Antibodies for B3GNT6: See all 23
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- ViGene Biosciences adenoviral particle packaged cDNA for B3GNT6 gene
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- Horizon Cell Lines for B3GNT6
- Cyagen custom Knockout/knockin (KOKI) mouse models for B3GNT6
- VectorBuilder custom plasmid, inducible vectors for B3GNT6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for B3GNT6
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for B3GNT6 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer