V3 here soon-try beta now
Gene Search (GeneCards Home) | GeneCards Guide | User Feedback | Terms of Use | Notice about third-party sites
 

B3GNT5 Gene

protein-coding   GIFtS: 49

GC03P184453
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases
B3GN-T5 1, 2
BGnT-5 3
Beta-1,3-N-acetylglucosaminyltransferase-5 3
Beta3Gn-T5 3
EC 2.4.1.- 3
beta3Gn-T5 1, 2
Descriptions
Lactotriaosylceramide synthase 3
Lc(3)Cer synthase 3
Lc3 synthase 3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase
5 2
beta 1,3 N-acetyglucosaminyltransferase Lc3 synthase 2
beta-1,3-N-acetylglucosaminyltransferase bGnT-5 2
External Ids
HGNC: 156841
Entrez Gene: 840022
UniProtKB: Q9BYG03
Ensembl: ENSG000001765977
Search outside databases for aliases for B3GNT5 gene

Previous GC identifers: GC03P179760 GC03P183826 GC03P184373 GC03P184291

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for B3GNT5:
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a
type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates
and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is
essential for the expression of Lewis X epitopes on glycolipids. [provided by RefSeq]

UniProtKB/Swiss-Prot: B3GN5_HUMAN, Q9BYG0
Function: Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto-
or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of
HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer)
and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer
and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in
regulating neolacto-series glycolipid synthesis during embryonic development

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the B3GNT5 gene  

Entrez Gene cytogenetic band: 3q28   Ensembl cytogenetic band:  3q27.1   HGNC cytogenetic band: 3q28

B3GNT5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P184453:     (about GC identifiers)

Start:
184,453,726 bp from pter
End:
184,473,873 bp from pter
Size:
20,148 bases
Orientation:
plus strand
RefSeq DNA sequence:
NC_000003.10  NT_005612.15  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: B3GN5_HUMAN, Q9BYG0 (See protein sequence)
Recommended Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5  
Size: 378 amino acids; 44053 Da
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (By
similarity)
Sequence caution: Sequence=BAD92754.1; Type=Frameshift; Positions=347;
Secondary accessions: Q59FE3 Q7L9Z5 Q8WWP9

REFSEQ proteins: NP_114436.1  

ENSEMBL proteins: 
ENSP00000316173 


Human Recombinant Proteins 
Browse Drug Discovery Central at Invitrogen for human recombinant proteins
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich  
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Recombinant Proteins from Abcam (B3GNT5)
Human Recombinant Proteins from Abnova (B3GNT5)
                Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

5 Gene Ontology (GO) cellular component terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0000139 Golgi membrane IEA--
GO:0005622 intracellular IDA11384981
GO:0005794 Golgi apparatus IEA--
GO:0016020 membrane IEA--
GO:0016021 integral to membrane IEA--
About this table

Antibodies for B3GNT5: 
Browse Antibodies Central at Invitrogen
Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Sigma-Aldrich Antibodies for B3GNT5
Browse R&D Systems for Antibodies
Antibodies from Abcam (B3GNT5), each with their AbpromiseSM
Monoclonal and Polyclonal Antibodies from Abnova (B3GNT5)
Novus Biologicals Antibodies for B3GNT5

Assays for B3GNT5: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
Browse R&D Systems for biochemical assays
Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

1 InterPro domain/family:
 IPR002659 Glyco_trans_31


   GeneDecks  B3GNT5 for the domains selected above  
About GeneDecksing

Graphical View of Domain Structure for InterPro Entry Q9BYG0

ProtoNet protein and cluster: Q9BYG0

1 Blocks protein family: IPB002659 Glycosyl transferase

UniProtKB/Swiss-Prot: B3GN5_HUMAN, Q9BYG0
Similarity: Belongs to the glycosyltransferase 31 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib.
RNA:
Invitrogen RNAi Products for gene knock-down (B3GNT5)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_032047

              Applied Biosystems Silencer® siRNAs for B3GNT5

              Sigma-Aldrich siRNA for B3GNT5  
                     Sigma-Aldrich shRNA for B3GNT5  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Invitrogen Clones for B3GNT5
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_032047
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_032047
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_032047 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_032047

UniProtKB/Swiss-Prot: B3GN5_HUMAN, Q9BYG0
Function: Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto-
or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of
HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer)
and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer
and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in
regulating neolacto-series glycolipid synthesis during embryonic development
Induction: Up-regulated by stimulation with retinoic acid and down-regulated with
12-O-tetradecanoylphorbol-13-acetate
Enzyme Number (IUBMB): EC 2.4.1.- 

1 MGI mutant phenotype (inferred from 1 allele(MGI details for B3gnt5):

lethality-prenatal/perinatal

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0008378 galactosyltransferase activity IEA--
GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity IDA11384981
GO:0008917 lipopolysaccharide N-acetylglucosaminyltransferase activity IEA--
GO:0016757 transferase activity, transferring glycosyl groups IEA--
About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section


2 Sigma-Aldrich "Your Favorite Gene" Pathways for  B3GNT5  (Your Favorite Gene powered by Ingenuity) 
 Glycosphingolipid Biosynthesis - Neolactoseries
 Glycosphingolipid Biosynthesis - Lactoseries

   GeneDecks  B3GNT5 for the pathways selected above  
About GeneDecksing

1 Kegg Pathway  (Kegg details for B3GNT5):
 hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series

   GeneDecks  B3GNT5 for the pathways selected above  
About GeneDecksing
UniProtKB/Swiss-Prot: B3GN5_HUMAN, Q9BYG0
Pathway: Protein modification; protein glycosylation


5/10 Interacting proteins for B3GNT5 (ENSP000003161733) via UniProtKB, MINT, and/or STRING (see all 10 )

InteractantInteraction Details
GeneCardExternal ID(s)
B4GALT4ENSP000003521443STRING (score=.97)
B3GALT1ENSP000003037403STRING (score=.899)
B3GALT2ENSP000003564043STRING (score=.899)
B3GALT5ENSP000003699923STRING (score=.899)
B4GALT1ENSP000003690553STRING (score=.899)
About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0006486 protein amino acid glycosylation TAS11384981
GO:0007275 multicellular organismal development IEA--
GO:0007417 central nervous system development IDA11384981
GO:0009247 glycolipid biosynthetic process TAS11384981
About this table
(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences
Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for B3GNT5

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib.
RNA:
Invitrogen RNAi Products for gene knock-down (B3GNT5)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_032047

              Sigma-Aldrich siRNA for B3GNT5  
                     Sigma-Aldrich shRNA for B3GNT5  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_032047  

REFSEQ mRNAs for B3GNT5 gene: 

NM_032047.4   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_032047  

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_032047
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_032047
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_032047 

Additional cDNA sequence: 

AB045278.1 AB209517.1 AF368169.1 AJ304505.1 AK074235.1 AK074424.1 AK091474.1 BC013229.1 
BC040935.1 

11 DOTS entries:

DT.91907482  DT.311018  DT.92028182  DT.100785405  DT.100785406  DT.120868479  DT.120868381  DT.120868418 
DT.40111816  DT.95162130  DT.95162132 

24/123 AceView cDNA sequences (see all 123 ):

AW516070 AJ304505 BF223815 BM142526 AK126337 N57022 BU684277 BF940440 
BC028058 BQ722475 AI825936 BM142352 NM_032047 AX747008 AB045278 AI467964 
BX499010 BF109408 AW026723 AW452443 AK091474 BG236076 D81847 AK074235 

highest scoring ESTs for B3GNT5:

AI825936 AA043551 AA369063 AA670337 AB045278 AF368169 AI039673 AI391576 AI445181 AI561139 

Unigene Cluster for B3GNT5:

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
Hs.718506  [show with all ESTs]
Unigene Representative Sequence: NM_032047


GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for B3GNT5

ExUns: 1 ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b · 5c · 5d
SP1:                                                                  
SP2:                                -                                 
SP3:                          -     -                                 
SP4:        -     -     -     -     -     -                           
SP5:              -     -     -     -     -                           

About this scheme

ECgene alternative splicing isoforms for B3GNT5

1 Ensembl transcript including schematic representation:
ENST00000326505  
(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

B3GNT5 expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for B3GNT5

1 / 2 / 3

5 probe-sets matching B3GNT5 gene


Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
47573_at2, 3 U95-B 1 1.00 1.00 0.98 1.09 AI825936 1.00 1.00 1.00 1
67280_at2, 3 U95-E 1 0.94 1.00 0.97 0.91 AI243125 0.80 0.80 0.80 1

225612_s_at2, 3 U133-B 1 1.00 1.00 -- -- BE672260 0.80 1.00 0.91 1

225612_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

1554835_a_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
GeneDecks  B3GNT5 for binary patterns associated with the probe-sets selected above  
About GeneDecksing
About this table    
Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: TTCCTTGTAA

SOURCE GeneReport for Unigene cluster: Hs.718506

UniProtKB/Swiss-Prot: B3GN5_HUMAN, Q9BYG0
Tissue specificity: Widely expressed. Highly expressed in lung, colon, placenta, testis, pituitary
gland and cerebellum. Weakly expressed in brain, liver, spleen, lymph node and thymus

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section


Orthologs for B3GNT5 gene from 5/6 species (see all 6 )
Organism Gene Locus Description Human
Similarity
NCBI accessions
chimpanzee
(Pan troglodytes)
B3GNT51   -- UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase more 99.71(n)
100(a)
735383  XM_001134746.1  XP_001134746.1 
cow
(Bos taurus)
B3GNT51   -- UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase more 86.57(n)
87.06(a)
767899  NM_001076979.1  NP_001070447.1 
rat
(Rattus norvegicus)
B3gnt51   -- UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase more 82.36(n)
80.05(a)
116740  XM_344040.3  XP_344041.2 
mouse
(Mus musculus)
B3gnt51, 5 165
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase more1, 5 84(n)1
80(a)1
1081051  NM_054052.21  NP_473393.21 
 AB0596205  AI0471195  (see all 14)
chicken
(Gallus gallus)
B3GNT51   -- UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase more 75.65(n)
72.24(a)
424960  XM_422769.2  XP_422769.2 
About this table        Species with no ortholog for B3GNT5

ENSEMBL Gene Tree for B3GNT5
(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

Paralogs for B3GNT5 gene
B3GALT42  ENSG000002146542  

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

  --
(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

  --

(Possibly Related Articles in Doctor's Guide)
About This Section

  --

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
About This Section

8 PubMed articles for B3GNT5 gene:
(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)
(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 84002 HGNC: 15684 AceView: B3GNT5 Ensembl:ENSG00000176597 euGenes: HUgn84002
ECgene: B3GNT5 H-InvDB: B3GNT5
(According to HUGE)
About This Section

  --
(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

NameDescription
GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=B3GNT5
Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_538
(Available from WIS Yeda, Salk, Tufts)
About This Section

  --
(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section



Products for B3GNT5:
 TaqMan ® Gene Expression Assays
 TaqMan ® Genotyping Assays
  Free SNP selection tool



  Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
  Invitrogen Antibodies  Invitrogen Assays
  Invitrogen Clones  Invitrogen Q-PCR Products
  Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
  Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for B3GNT5-related products

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
 Millipore Immunoassay Services
 Millipore Target Screening & Profiling Services


 Predesigned and custom siRNAs for B3GNT5 Antibodies for B3GNT5
 Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
 Lentivirus-delivered shRNAs for B3GNT5 Browse small molecules at Sigma-Aldrich
 "Your Favorite Gene" Pathwaysfeedback


  
 Antibodies   Primer Pairs  
 Cell Culture Products   ELISAs  
 Flow Cytometry Kits   Protease Activity Assays & Reagents  
 Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
 Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
 Recombinant & Natural Proteins  

 Recombinant Proteins (B3GNT5)
 Antibodies (B3GNT5)
 Search for Chimera RNAi
 Custom Service for Mouse Mab
 Custom Service for Rabbit Pab from Full-length Protein
  
 Search for Antibodies & Assays

 Recombinant Proteins
(B3GNT5)
 Antibodies (B3GNT5)
 Search OriGene for B3GNT5
 Search Tocris compounds for B3GNT5




 Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
 Antibodies for B3GNT5

GeneCards Homepage    -    Last full update: 2 Jul 2009        Incremental update: 13 Oct 2009

Random Gene From GIFtS : about GIFtS

Gene Index:   3   5   A   B   C   D   E   F   G   H   I   J   K   L   M   N   O   P   Q   R   S   T   U   V   W   X   Y   Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science



The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
B3GNT5 Gene at Home site.
Version 2.41.1
server5.xennexinc.com