Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

B3GNT4 Gene

protein-coding GIFtS: 51
GCID: GC12P122689

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase...

Search for B3GNT4
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 4¹ ²		Beta-1,3-Gn-T4³
B3GN-T4¹ ²		Beta-1,3-N-Acetylglucosaminyltransferase BGn-T4²
Beta3Gn-T4³		Beta-1,3-Gn-T4³
Beta-1,3-N-Acetylglucosaminyltransferase 4² ³		Beta3Gn-T4³
BGnT-4² ³		EC 2.4.1.-³

External Ids:	HGNC: 15683¹	Entrez Gene: 79369²	Ensembl: ENSG00000176383⁷	OMIM: 605864⁵	UniProtKB: Q9C0J1³

Export aliases for B3GNT4 gene to outside databases

Previous GC identifers: GC12M121471 GC12M122667 GC12P122496 GC12P121125 GC12P121212 GC12P119649

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for B3GNT4:

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase protein family. The encoded enzyme is

involved in the biosynthesis of poly-N-acetyllactosamine chains and prefers lacto-N-neotetraose as a substrate. It is

a type II transmembrane protein. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: B3GN4_HUMAN, Q9C0J1

Function: Has a beta-1,3-N-acetylglucosaminyltransferase activity for type 2 oligosaccharides

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_009755.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the B3GNT4 gene promoter:
STAT1 Brachyury ATF-2 STAT1beta Meis-1b STAT1alpha STAT3 Meis-1a c-Jun Meis-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: B3GNT4 promoter sequence

Search SABiosciences Chromatin IP Primers for B3GNT4

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B3GNT4

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24 Ensembl cytogenetic band: 12q24.31 HGNC cytogenetic band: 12q24

B3GNT4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B3GNT4 gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12P122689: view genomic region (about GC identifiers)

Start:	122,688,090 bp from pter	End:	122,693,499 bp from pter
Size:	5,410 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: B3GN4_HUMAN, Q9C0J1 (See protein sequence)

Recommended Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

Size: 378 amino acids; 42310 Da

Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (By similarity)

Sequence caution: Sequence=AAL37219.1; Type=Erroneous initiation;

Secondary accessions: Q8N5W4 Q8N934 Q8ND21 Q8WWR5 Q8WY02 Q96QH5

Alternative splicing: 2 isoforms: Q9C0J1-1 Q9C0J1-2

Explore the universe of human proteins at neXtProt for B3GNT4: NX_Q9C0J1

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9C0J1

B3GNT4 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_110392.1

ENSEMBL proteins:

ENSP00000319636 ENSP00000438840 ENSP00000444534

Reactome Protein details: Q9C0J1
Human Recombinant Protein Products for B3GNT4:

	Browse Purified and Recombinant Proteins at EMD Millipore
	R&D Systems Recombinant & Natural Proteins for B3GNT4 (Beta-1,3-N-Acetylglucosaminyltransferase 4/B3GNT4)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: B3GNT4 OriGene Custom Protein Services for B3GNT4
	GenScript Custom Purified and Recombinant Proteins Services for B3GNT4
	Novus Biologicals B3GNT4 Protein Novus Biologicals B3GNT4 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Uscn

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	TAS	--
GO:0016021	integral to membrane	IEA	--

B3GNT4 for ontologies About GeneDecksing

B3GNT4 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for B3GNT4
	GenScript Custom Superior Antibodies Services for B3GNT4
	Novus Biologicals B3GNT4 Antibody
	Abcam antibodies for B3GNT4
	Browse Antibodies at Uscn
	ThermoFisher Antibody for B3GNT4

Assay Products for B3GNT4:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for B3GNT4
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

B3GNT4 for domains About GeneDecksing

1 InterPro domain/family:

IPR002659 Glyco_trans_31

Graphical View of Domain Structure for InterPro Entry Q9C0J1

ProtoNet protein and cluster: Q9C0J1

1 Blocks protein family: IPB002659 Glycosyl transferase

UniProtKB/Swiss-Prot: B3GN4_HUMAN, Q9C0J1

Similarity: Belongs to the glycosyltransferase 31 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: B3GN4_HUMAN, Q9C0J1

Function: Has a beta-1,3-N-acetylglucosaminyltransferase activity for type 2 oligosaccharides

Enzyme Number (IUBMB): EC 2.4.1.-¹

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008378	galactosyltransferase activity	IEA	--

B3GNT4 for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for B3GNT4:

G0/1 arrest

Increased G1 DNA content

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for B3GNT4

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat B3GNT4
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate B3GNT4
		SwitchGear 3'UTR luciferase reporter plasmid: B3GNT4 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for B3GNT4 (see all 7) OriGene shRNA RFP: B3GNT4 OriGene siRNA: B3GNT4
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat B3GNT4
		Sirion Biotech Custom design and validation of potent shRNA sequences against B3GNT4

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for B3GNT4
			Sirion Biotech Customized adenovirus for overexpression of B3GNT4 Sirion Biotech Customized adenovirus for potent knockdown of B3GNT4

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for B3GNT4 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for B3GNT4 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: B3GNT4 (NM_030765)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for B3GNT4
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat B3GNT4

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for B3GNT4
		Search LifeMap BioReagents cell lines for B3GNT4
		Sirion Biotech Customized stable knockdown cell line services for B3GNT4 Sirion Biotech Customized inducible knockdown cell line services for B3GNT4 Sirion Biotech Customized stable overexpressing cell line services for B3GNT4 Sirion Biotech Customized inducible overexpressing cell line services for B3GNT4

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B3GNT4

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

MPS IIIC - Sanfilippo syndrome C

8/14 pathways (see all 14)
MPS IIIC - Sanfilippo syndrome C	1.00	MPS IIIA - Sanfilippo syndrome A	1.00
MPS I - Hurler syndrome	1.00	MPS IIID - Sanfilippo syndrome D	1.00
Mucopolysaccharidoses	1.00	MPS IX - Natowicz syndrome	1.00
MPS IV - Morquio syndrome A	1.00	MPS II - Hunter syndrome	1.00

Keratan sulfate biosynthesis

Keratan sulfate biosynthesis

1.00

Keratan sulfate/keratin metabolism

0.84

Metabolism

Metabolism

1.00

Metabolic pathways

0.38

Asparagine N-linked glycosylation

Post-translational protein modification

0.44

Metabolism of proteins

0.15

Disease

Disease

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

5/21 Reactome Pathways for B3GNT4 (see all 21)

	MPS VI - Maroteaux-Lamy syndrome
	Metabolism
	Disease
	Keratan sulfate/keratin metabolism
	MPS II - Hunter syndrome

2 Kegg Pathways (Kegg details for B3GNT4):

	Glycosphingolipid biosynthesis - lacto and neolacto series
	Metabolic pathways

UniProtKB/Swiss-Prot: B3GN4_HUMAN, Q9C0J1

Pathway: Protein modification; protein glycosylation

B3GNT4 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for B3GNT4

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/51 Interacting proteins for B3GNT4 (Q9C0J1^{2, 3} ENSP00000319636⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 51)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GOLM1	Q8NBJ4²^,³, ENSP00000373363⁴	MINT-64978 I2D: score=4 STRING: ENSP00000373363
B3GNT2	ENSP00000305595⁴	STRING: ENSP00000305595
FUT1	ENSP00000312021⁴	STRING: ENSP00000312021
FUT2	ENSP00000375748⁴	STRING: ENSP00000375748
FUT3	ENSP00000305603⁴	STRING: ENSP00000305603

About this table

Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005975	carbohydrate metabolic process	TAS	--
GO:0016266	O-glycan processing	TAS	--
GO:0018146	keratan sulfate biosynthetic process	TAS	--
GO:0030203	glycosaminoglycan metabolic process	TAS	--
GO:0042339	keratan sulfate metabolic process	TAS	--

B3GNT4 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for B3GNT4
Search CenterWatch for drugs/clinical trials and news about B3GNT4 / B3GN4

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for B3GNT4 gene:

NM_030765.2

Unigene Cluster for B3GNT4:

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

Hs.363315 [show with all ESTs]

Unigene Representative Sequence: AY358940

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000324189(uc001ubx.3) ENST00000546192(uc001uby.3) ENST00000545141

ENST00000537991 ENST00000538257 ENST00000535274

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat B3GNT4
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate B3GNT4
		SwitchGear 3'UTR luciferase reporter plasmid: B3GNT4 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for B3GNT4 (see all 7) OriGene shRNA RFP: B3GNT4 OriGene siRNA: B3GNT4
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat B3GNT4
		Sirion Biotech Custom design and validation of potent shRNA sequences against B3GNT4

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for B3GNT4 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for B3GNT4 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: B3GNT4 (NM_030765)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for B3GNT4
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat B3GNT4

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for B3GNT4 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat B3GNT4
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat B3GNT4
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat B3GNT4

Additional cDNA sequence:

AB049586.1 AJ130848.1 AJ278962.1 AL834452.1 AY358940.1 BC031399.1

3 DOTS entries:

DT.431320 DT.100031197 DT.95297085

24/39 AceView cDNA sequences (see all 39):

BX108933 CR591685 R41690 NM_030765 BC031399 BC030247 BX090781 AJ278962

AA936705 AL834452 CA416426 BI916321 AY358940 AA133381 AB049586 AI910059

AK095746 AJ130848 AA704041 AL522684 AW207332 AI961337 AL522683 BM820715

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

B3GNT4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGGCACTGG

About this image

B3GNT4 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See B3GNT4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for B3GNT4

SOURCE GeneReport for Unigene cluster: Hs.363315

UniProtKB/Swiss-Prot: B3GN4_HUMAN, Q9C0J1

Tissue specificity: Mainly expressed in brain tissues such as whole brain, hippocampus, amygdala, cerebellum and

caudate nucleus. Also expressed in colon, esophagus and kidney

SABiosciences Expression via Pathway-Focused PCR Array including B3GNT4:

Glycosylation in human mouse rat

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for B3GNT4 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat B3GNT4
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat B3GNT4
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat B3GNT4

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B3GNT4

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for B3GNT4 gene from 4/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	LOC100858043¹	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase more	68.7(n) 65.24(a)		100858043 XM_003642193.1 XP_003642241.1
lizard (Anolis carolinensis)	Reptilia	B3GNT4⁶	--	55(a)	1 ↔ 1	GL343423.1(1408-2502)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.20273²	Transcribed sequence with weak similarity to protein more	78.94(n)		AL775073.2
fruit fly (Drosophila melanogaster)	Insecta	CG30036⁶ CG30037⁶ (see all 5)	--	20(a) 16(a) (see all 5)	many ↔ many many ↔ many (see all 5)	2R(7865038-7866454) 2R(7866598-7867990)

ENSEMBL Gene Tree for B3GNT4 (if available)
TreeFam Gene Tree for B3GNT4 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for B3GNT4 gene

B3GNT3² B3GNT2² B3GNT5² B3GALT5² B3GALT1² B3GALT4² B3GNT7² B3GALT2²

B3GNT8² B3GNT6² B3GALNT1² B3GNT9²

8 SIMAP similar genes for B3GNT4 using alignment to 1 protein entry: B3GN4_HUMAN:

B3GNT2 B3GNT3 B3GNT6 B3GNT7 B3GNT5 B3GALT1

B3GNT8 B3GNT9

B3GNT4 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs143645169^1,2		--	122686292(+)	`AACTGA/GGAGGG`	3	--	us2k¹ int¹		0	--	--	--	--
rs114577725^1,2	F	--	122686320(+)	`AGTGCC/TGTGGG`	3	--	int¹ us2k¹		1		WA	118
rs190361433^1,2		--	122686353(+)	`GCCCGA/CTCATA`	3	--	us2k¹ int¹		0	--	--	--	--
rs10848035^1,2	C,F,A,H	--	122686437(+)	`GCACTT/GTGGCG`	3	--	us2k¹ int¹ tfbs³		11		NS EA NA	672
rs138318016^1,2		--	122686442(+)	`TTGGCA/GTGCGG`	3	--	int¹ us2k¹		0	--	--	--	--
rs112126053^1,2		--	122686446(+)	`CGTGCG/AGATCA`	3	--	us2k¹ int¹		3		CSA WA EA	240
rs182490916^1,2		--	122686469(+)	`AGTTCA/GAGACC`	3	--	us2k¹ int¹		0	--	--	--	--
rs12371512^1,2	C,F,H	--	122686637(+)	`TTTCAC/TGCCAG`	3	--	us2k¹ int¹		10		NS EA NA	1096
rs113262896^1,2	C	--	122686753(+)	`AAAGGT/-TTTTT`	3	--	us2k¹ int¹		1		CSA	2
rs143896618^1,2		--	122686790(+)	`TTAATG/TGAAGA`	3	--	us2k¹ int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for B3GNT4 (122688090 - 122693499 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for B3GNT4: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing B3GNT4

DNA2.0 Custom Variant and Variant Library Synthesis for B3GNT4

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

B3GNT4 for disorders About MalaCards

B3GNT4 for disorders About GeneDecksing

OMIM gene information: 605864 OMIM disorders: --

Export disorders for B3GNT4 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for B3GNT4 gene integrated from 9 sources:
(articles sorted by number of sources associating them with B3GNT4)

Utopia: connect your pdf to the dynamic
world of online information

Identification and characterization of three novel beta 1,3-N- acetylglucosaminyltransferases structurally related to the beta 1,3- galactosyltransferase family. (PubMed id 11042166)^{1, 2, 3} Shiraishi N....Sasaki K. (2001)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. (PubMed id 10580128)^{1, 2} Amado M.... Clausen H. (1999)
Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)¹ Bennett E.J....Harper J.W. (2010)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)¹ Stelzl U.... Wanker E.E. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 79369	HGNC: 15683	AceView: B3GNT4	Ensembl:ENSG00000176383	euGenes: HUgn79369
ECgene: B3GNT4	Kegg: 79369	H-InvDB: B3GNT4

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for B3GNT4	Pharmacogenomics, SNPs, Pathways
GGDB	http://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=B3GNT4

Intellectual Property for B3GNT4 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for B3GNT4 gene:
Search GeneIP for patents involving B3GNT4

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Recombinant/Natural Proteins for B3GNT4 (Beta-1,3-N-Acetylglucosaminyltransferase 4/B3GNT4)

	Browse OriGene Antibodies		OriGene shRNA RFP for B3GNT4
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for B3GNT4		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for B3GNT4
	OriGene Protein Over-expression Lysate for B3GNT4		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for B3GNT4		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for B3GNT4		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for B3GNT4
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for B3GNT4		OriGene Custom Protein Services for B3GNT4
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat B3GNT4
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing B3GNT4
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B3GNT4
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat B3GNT4
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat B3GNT4
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat B3GNT4

	GenScript Custom Purified and Recombinant Proteins Services for B3GNT4		GenScript cDNA clones with any tag delivered in your preferred vector for B3GNT4
	GenScript Custom Assay Services for B3GNT4		GenScript Custom Superior Antibodies Services for B3GNT4
	GenScript Custom overexpressing Cell Line Services for B3GNT4		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in B3GNT4 promoter
	Search Chromatin IP Primers for B3GNT4
	RT² qPCR Primer Assay in human, mouse, rat B3GNT4
	Search GNC Networks for B3GNT4
	SABiosciences PCR Arrays including human, mouse, rat B3GNT4

Search Tocris compounds for B3GNT4

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	B3GNT4 antibodies
	B3GNT4 proteins
	B3GNT4 lysates

	Antibodies for B3GNT4
	See all of Abcam's Antibodies, Kits and Proteins for B3GNT4
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

Browse ELISAs, CLIAs, Proteins, and Antibodies at Uscn

Search LifeMap BioReagents cell lines for B3GNT4

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B3GNT4

	SwitchGear 3'UTR luciferase reporter plasmids for B3GNT4
	SwitchGear Promoter luciferase reporter plasmids for B3GNT4

ThermoFisher Antibody for B3GNT4

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat B3GNT4

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for B3GNT4

Sirion Biotech Customized:

	stable knockdown cell line services for B3GNT4
	inducible knockdown cell line services for B3GNT4
	design and validation of potent shRNA sequences against B3GNT4
	adenovirus for potent knockdown of B3GNT4
	adenovirus for overexpression of B3GNT4
	stable overexpressing cell line services for B3GNT4
	inducible overexpressing cell line services for B3GNT4

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes B3GNT4 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

B3GNT4 Gene

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase...

Aliases
for B3GNT4 gene

Summaries
for B3GNT4 gene

Genomic Views
for B3GNT4 gene

Proteins
for B3GNT4 gene

Protein Domains /
Families
for B3GNT4 gene

Function
for B3GNT4 gene

Pathways & Interactions
for B3GNT4 gene

Drugs & Compounds
for B3GNT4 gene

Transcripts
for B3GNT4 gene

Expression
for B3GNT4 gene

Orthologs
for B3GNT4 gene

Paralogs
for B3GNT4 gene

Genomic Variants
for B3GNT4 gene

Disorders / Diseases
for B3GNT4 gene

Publications
for B3GNT4 gene

External Searches for B3GNT4 gene

Genome Databases showing B3GNT4 gene

Other Databases showing B3GNT4 gene

Specialized Databases showing B3GNT4 gene

Intellectual Property
for B3GNT4 gene

Products
for B3GNT4 gene

View Random Gene

Advanced Search

Export list of displayed genes

B3GNT4 Gene

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase...

Aliasesfor B3GNT4 gene

Summariesfor B3GNT4 gene

Genomic Viewsfor B3GNT4 gene

Proteinsfor B3GNT4 gene

Protein Domains /Familiesfor B3GNT4 gene

Functionfor B3GNT4 gene

Pathways & Interactionsfor B3GNT4 gene

Drugs & Compoundsfor B3GNT4 gene

Transcriptsfor B3GNT4 gene

Expression for B3GNT4 gene

Orthologsfor B3GNT4 gene

Paralogsfor B3GNT4 gene

Genomic Variantsfor B3GNT4 gene

Disorders / Diseasesfor B3GNT4 gene

Publicationsfor B3GNT4 gene

External Searches for B3GNT4 gene

Genome Databases showing B3GNT4 gene

Other Databases showing B3GNT4 gene

Specialized Databases showing B3GNT4 gene

Intellectual Propertyfor B3GNT4 gene

Productsfor B3GNT4 gene

View Random Gene

Aliases
for B3GNT4 gene

Summaries
for B3GNT4 gene

Genomic Views
for B3GNT4 gene

Proteins
for B3GNT4 gene

Protein Domains /
Families
for B3GNT4 gene

Function
for B3GNT4 gene

Pathways & Interactions
for B3GNT4 gene

Drugs & Compounds
for B3GNT4 gene

Transcripts
for B3GNT4 gene

Expression
for B3GNT4 gene

Orthologs
for B3GNT4 gene

Paralogs
for B3GNT4 gene

Genomic Variants
for B3GNT4 gene

Disorders / Diseases
for B3GNT4 gene

Publications
for B3GNT4 gene

Intellectual Property
for B3GNT4 gene

Products
for B3GNT4 gene