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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

B3GNT2 Gene

protein-coding   GIFtS: 56
GCID: GC02P062423

UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase...

(Previous name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase...)
(Previous symbol: B3GNT1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 21 2     BGnT-13
B3GNT11 2 3     Beta-1,3-Gn-T13
UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 11 2     Beta-1,3-Gn-T23
BGnT-22 3     Beta-3-Gx-T73
B3GN-T22     Beta3Gal-T73
B3GNT2     Beta3GalT73
B3GNT-22     Beta3Gn-T13
BETA3GNT2     Beta3Gn-T23
BGNT22     EC 2.4.1.-3
beta-1,3-Gn-T12     b3Gal-T73
beta-1,3-Gn-T22     Beta-1,3-Galactosyltransferase 73
Beta-1,3-N-Acetylglucosaminyltransferase BGnT-12     Beta-1,3-GalTase 73
Beta-1,3-N-Acetylglucosaminyltransferase BGnT-22     Beta-1,3-N-Acetylglucosaminyltransferase 13
beta3Gn-T12     Beta-1,3-N-Acetylglucosaminyltransferase 23
beta3Gn-T22     UDP-Gal:Beta-GlcNAc Beta-1,3-Galactosyltransferase 73
B3GALT73     UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,3-Galactosyltransferase 73

External Ids:    HGNC: 156291   Entrez Gene: 106782   Ensembl: ENSG000001703407   OMIM: 6055815   UniProtKB: Q9NY973   

Export aliases for B3GNT2 gene to outside databases

Previous GC identifer: GC02P062276


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for B3GNT2 Gene:
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II
transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of
poly-N-acetyllactosamine chains. (provided by RefSeq, Jul 2008)

GeneCards Summary for B3GNT2 Gene: 
B3GNT2 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2) is a protein-coding gene. Diseases associated with B3GNT2 include morquio syndrome b, and pancreatic cancer, and among its related super-pathways are Keratan sulfate/keratin metabolism and Metabolic pathways. GO annotations related to this gene include UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity. An important paralog of this gene is B3GNT3.

UniProtKB/Swiss-Prot: B3GN2_HUMAN, Q9NY97
Function: Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains

Gene Wiki entry for B3GNT2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_022184.15  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the B3GNT2 gene promoter:
         Pbx1a   AML1a   Pax-5   Brachyury   ATF-2   Nkx2-5   STAT5A   Nkx5-1   CREB   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidB3GNT2 promoter sequence
   Search SABiosciences Chromatin IP Primers for B3GNT2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B3GNT2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p15   Ensembl cytogenetic band:  2p15   HGNC cytogenetic band: 2p15

B3GNT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B3GNT2 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P062423:  view genomic region     (about GC identifiers)

Start:
62,423,248 bp from pter      End:
62,451,866 bp from pter
Size:
28,619 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: B3GN2_HUMAN, Q9NY97 (See protein sequence)
Recommended Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2  
Size: 397 amino acids; 46022 Da
Cofactor: Manganese
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (Potential)
Caution: Was indicated as B3Gal-T6 in submitted DNA entries
Sequence caution: Sequence=BAA92031.1; Type=Erroneous initiation;
Secondary accessions: Q54AC1 Q9NQQ9 Q9NQR0 Q9NUT9
Alternative splicing: 2 isoforms:  Q9NY97-1   Q9NY97-2   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for B3GNT2: NX_Q9NY97

Explore proteomics data for B3GNT2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NY97

  • B3GNT2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    B3GNT2 Protein Expression
    REFSEQ proteins: NP_006568.2  
    ENSEMBL proteins: 
     ENSP00000305595   ENSP00000384692  
    Reactome Protein details: Q9NY97
    Human Recombinant Protein Products for B3GNT2: 
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    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0016020membrane ----
    GO:0016021integral to membrane NAS--

    B3GNT2 for ontologies           About GeneDecksing



    B3GNT2 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    B3GT: Beta 3-glycosyltransferases

    1 InterPro protein domain:
     IPR002659 Glyco_trans_31

    Graphical View of Domain Structure for InterPro Entry Q9NY97

    ProtoNet protein and cluster: Q9NY97

    1 Blocks protein domain: IPB002659 Glycosyl transferase

    UniProtKB/Swiss-Prot: B3GN2_HUMAN, Q9NY97
    Similarity: Belongs to the glycosyltransferase 31 family


    B3GNT2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: B3GN2_HUMAN, Q9NY97
    Function: Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains

         Enzyme Number (IUBMB): EC 2.4.1.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008378galactosyltransferase activity ----
    GO:0008499UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity NAS--
         
    B3GNT2 for ontologies           About GeneDecksing


    Phenotypes:
         8 MGI mutant phenotypes (inferred from 3 alleles(MGI details for B3gnt2):
     behavior/neurological  cellular  craniofacial  hematopoietic system  immune system 
     nervous system  respiratory system  taste/olfaction 

    B3GNT2 for phenotypes           About GeneDecksing

    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidB3GNT2 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for B3GNT2 About   (see all 7)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Keratan sulfate biosynthesis
    Keratan sulfate biosynthesis0.82
    Glycosaminoglycan biosynthesis - keratan sulfate0.43
    Keratan sulfate/keratin metabolism0.82
    2Metabolism
    Metabolism0.40
    Metabolic pathways0.40
    3MPS IIIC - Sanfilippo syndrome C
    MPS IIIC - Sanfilippo syndrome C0.48
    Glycosaminoglycan metabolism0.48
    MPS IV - Morquio syndrome A0.48
    MPS IIID - Sanfilippo syndrome D0.48
    MPS VI - Maroteaux-Lamy syndrome0.48
    MPS I - Hurler syndrome0.48
    MPS IV - Morquio syndrome B0.48
    MPS IX - Natowicz syndrome0.48
    4Asparagine N-linked glycosylation
    Post-translational protein modification0.44
    Metabolism of proteins0.35
    5O-linked glycosylation of mucins
    O-linked glycosylation of mucins0.44

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    5/21        Reactome Pathways for B3GNT2 (see all 21)
        MPS VI - Maroteaux-Lamy syndrome
    Metabolism
    Disease
    Keratan sulfate/keratin metabolism
    MPS II - Hunter syndrome


    3         Kegg Pathways  (Kegg details for B3GNT2):
        Glycosaminoglycan biosynthesis - keratan sulfate
    Glycosphingolipid biosynthesis - lacto and neolacto series
    Metabolic pathways

    UniProtKB/Swiss-Prot: B3GN2_HUMAN, Q9NY97
    Pathway: Protein modification; protein glycosylation


    B3GNT2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for B3GNT2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/54 Interacting proteins for B3GNT2 (Q9NY973 ENSP000003055954) via UniProtKB, MINT, STRING, and/or I2D (see all 54)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    C1GALT1C1Q96EU73, ENSP000003043644I2D: score=1 STRING: ENSP00000304364
    B3GNT3ENSP000003218744STRING: ENSP00000321874
    B3GNT4ENSP000003196364STRING: ENSP00000319636
    B4GALT1ENSP000003690554STRING: ENSP00000369055
    B4GALT2ENSP000003492934STRING: ENSP00000349293
    About this table

    Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006486protein glycosylation ----
    GO:0007411axon guidance IEA--
    GO:0007608sensory perception of smell IEA--
    GO:0008150biological_process ND--

    B3GNT2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for B3GNT2 (B3GN2)

    3 HMDB Compounds for B3GNT2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Lacto-N-triaoseAgalacto-N-neotetraose (see all 5)75645-27-116277601
    Manganesemanganese 7439-96-5--
    Poly-N-acetyllactosaminePoly(N-acetyllactosamine) (see all 6)82441-98-3--

    Search CenterWatch for drugs/clinical trials and news about B3GNT2 / B3GN2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for B3GNT2 gene (2 alternative transcripts): 
    NM_006577.5  NM_033252.1  

    Unigene Cluster for B3GNT2:

    UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
    Hs.173203  [show with all ESTs]
    Unigene Representative Sequence: BC047933
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000301998(uc002sbs.3) ENST00000405767
    miRNA
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    Additional mRNA sequence: 

    AB049584.1 AF092051.2 AF288208.1 AF288209.1 AJ006077.1 AK002009.1 BC030579.2 BC047933.1 

    7 DOTS entries:

    DT.213887  DT.100748568  DT.100023248  DT.95164130  DT.121021177  DT.100716809  DT.121021201 

    24/124 AceView cDNA sequences (see all 124):

    BG319463 AA381631 AI638560 AW136376 BQ101164 AA377081 AA310578 AW613027 
    AA377082 AA873030 BX106672 BU753670 AA835126 AA936769 CK823150 BQ000660 
    AI862049 AA381830 BM557603 BQ029038 CD367444 D87736 BC047933 BU620612 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    B3GNT2 expression in normal human tissues (normalized intensities)      B3GNT2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATATTTTAAA
    B3GNT2 Expression
    About this image


    B3GNT2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Nose (Sensory Organs)    fully expand to see all 2 entries
             sensory organ/nose/nasal cavity   
     
     Gut Tube (Gastrointestinal Tract)
             Definitive endoderm-like cells ( A scalable, suspension protocol for derivation of...
     
     Neural Tube (Nervous System)
             Telencephalon
     
     Eye (Sensory Organs)
             Mature Rod Bipolar Cells Inner Nuclear Layer
     
     Brain (Nervous System)
             Cerebral Cortex

    See B3GNT2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for B3GNT2

    SOURCE GeneReport for Unigene cluster: Hs.173203

    UniProtKB/Swiss-Prot: B3GN2_HUMAN, Q9NY97
    Tissue specificity: Ubiquitous

        SABiosciences Expression via Pathway-Focused PCR Array including B3GNT2: 
              Glycosylation in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B3GNT2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for B3GNT2 gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia B3gnt21 , 5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 less1, 5 84.97(n)1
    87.41(a)1
      11 (14.22 cM)5
    536251  NM_001169114.11  NP_001162585.11 
     228347475 
    chicken
    (Gallus gallus)
    Aves B3GNT21 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 less 74.14(n)
    74.56(a)
      421286  NM_001008457.1  NP_001008457.1 
    lizard
    (Anolis carolinensis)
    Reptilia B3GNT26
    --
    (see all 3)
    --
    75(a)
    25(a)
    (see all 3)
    1 ↔ 1
    possible ortholog
    (see all 3)
    1(121385872-121387065)
    GL343939.1(35000-39529)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ039906.12   -- 72.65(n)    BJ039906.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa55h042 Danio rerio beta-3-galactosyltransferase (ssp5) mRNA, complete cds less 75.74(n)    AF321831.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta brn6
    brainiac
    26(a)
    1 → many
    X(3998377-3999824)
    worm
    (Caenorhabditis elegans)
    Secernentea bre-56
    Beta-1,3-galactosyltransferase bre-5
    21(a)
    1 → many
    IV(12049261-12051226)


    ENSEMBL Gene Tree for B3GNT2 (if available)
    TreeFam Gene Tree for B3GNT2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for B3GNT2 gene
    B3GNT32  B3GNT52  B3GALT52  B3GNT42  B3GALT12  B3GALT42  B3GALT22  B3GNT72  
    B3GNT82  B3GNT62  B3GALNT12  B3GNT92  
    8 SIMAP similar genes for B3GNT2 using alignment to 1 protein entry:     B3GN2_HUMAN:
    B3GNT4    B3GNT6    B3GNT3    B3GNT5    B3GNT7    B3GALT1
    B3GNT8    B3GNT9

    B3GNT2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for B3GNT2
    PGOHUM00000241460


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/544 SNPs in B3GNT2 are shown (see all 544)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1467048101,2
    C--62421667(+) TAACTC/GCCTTG 1 -- us2k10--------
    rs1402760721,2
    C--62421898(+) GTGGCA/TCTGTG 1 -- us2k10--------
    rs1864817151,2
    --62421932(+) TTCCTG/TTGCTG 1 -- us2k10--------
    rs1914780521,2
    --62422004(+) CTACTA/TAGCAA 1 -- us2k10--------
    rs1807571441,2
    --62422085(+) CTTAAG/TTGCTC 1 -- us2k10--------
    rs1860966791,2
    --62422203(+) GCGCAC/GGCGGG 1 -- us2k10--------
    rs678475861,2
    C--62422255(+) TCCAT-/CCGGTA 1 -- us2k10--------
    rs1458423911,2
    --62422453(+) AGTCCA/GGCCCT 1 -- us2k10--------
    rs1907318871,2
    --62422522(+) GCGCCA/CGGCAT 1 -- us2k10--------
    rs569100601,2
    C,F--62422798(+) GGGGGC/TGGCCG 1 -- us2k12Minor allele frequency- T:0.31WA 120

    HapMap Linkage Disequilibrium report for B3GNT2 (62423248 - 62451866 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for B3GNT2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv874231CNV Gain21882294
    nsv7313OTHER Inversion18451855

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605581    OMIM disorders: --

    6 diseases for B3GNT2:    About MalaCards
    morquio syndrome b    pancreatic cancer    colon cancer    pancreatitis
    rheumatoid arthritis    arthritis


    B3GNT2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): B3GNT2

    Export disorders for B3GNT2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for B3GNT2 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with B3GNT2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A beta-1,3-N-acetylglucosaminyltransferase with poly-N- acetyllactosamine synthase activity is structurally related to beta- 1,3-galactosyltransferases. (PubMed id 9892646)1, 2, 3, 9 Zhou D.... Hennet T. (1999)
    2. Identification and characterization of three novel beta 1,3-N- acetylglucosaminyltransferases structurally related to the beta 1,3- galactosyltransferase family. (PubMed id 11042166)1, 2, 3, 9 Shiraishi N....Sasaki K. (2001)
    3. Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. (PubMed id 22446963)1, 4 Okada Y....Yamamoto K. (2012)
    4. Genome-wide association study of ankylosing spondylit is identifies non-MHC susceptibility loci. (PubMed id 20062062)1, 4 (2010)
    5. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (2004)
    9. Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. (PubMed id 10580128)1, 2 Amado M.... Clausen H. (1999)
    10. A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. (PubMed id 22412388)4 Kenny E.E....Peter I. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10678 HGNC: 15629 AceView: B3GNT1 Ensembl:ENSG00000170340 euGenes: HUgn10678
    ECgene: B3GNT2 Kegg: 10678 H-InvDB: B3GNT2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for B3GNT2 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=B3GNT1
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_434

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for B3GNT2 gene:
    Search GeneIP for patents involving B3GNT2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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