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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

B3GNT1 Gene

protein-coding   GIFtS: 56
GCID: GC11M066112

UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase...

(Previous name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase...)
(Previous symbol: B3GNT6)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 11 2 3     Beta-1,3-N-Acetylglucosaminyltransferase BGnT-62
B3GNT61 2 3     i-beta-1,3-N-acetylglucosaminyltransferase2
UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 61 2     iGAT2
Poly-N-Acetyllactosamine Extension Enzyme2 3     iGNT2
EC 2.4.1.1493 8     N-Acetyllactosaminide Beta-1,3-N-Acetylglucosaminyltransferase2
3-N-acetylglucosaminyltransferase1     I-beta-1,3-N-acetylglucosaminyltransferase3
N-Acetyllactosaminide Beta-11     iGnT3
B3GN-T12     IGAT5
BETA3GNTI2     IGNT5
MDDGA132     

External Ids:    HGNC: 156851   Entrez Gene: 110412   Ensembl: ENSG000001746847   OMIM: 6055175   UniProtKB: O435053   

Export aliases for B3GNT1 gene to outside databases

Previous GC identifers: GC02P062551 GC02P062609 GC02P062380 GC02P062397 GC02P062334 GC11M065870


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for B3GNT1 Gene:
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II
transmembrane protein. It is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood
group i antigen. (provided by RefSeq, Jul 2008)

GeneCards Summary for B3GNT1 Gene: 
B3GNT1 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1) is a protein-coding gene. Diseases associated with B3GNT1 include kidney fibrosarcoma, and fibrosarcoma, and among its related super-pathways are Keratan sulfate/keratin metabolism and Metabolic pathways. GO annotations related to this gene include N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity. An important paralog of this gene is LARGE.

UniProtKB/Swiss-Prot: B3GN1_HUMAN, O43505
Function: Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans

Gene Wiki entry for B3GNT1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the B3GNT1 gene promoter:
         AP-1   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidB3GNT1 promoter sequence
   Search SABiosciences Chromatin IP Primers for B3GNT1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B3GNT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.2   Ensembl cytogenetic band:  11q13.2   HGNC cytogenetic band: 11q13.2

B3GNT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B3GNT1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M066112:  view genomic region     (about GC identifiers)

Start:
66,112,843 bp from pter      End:
66,115,163 bp from pter
Size:
2,321 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: B3GN1_HUMAN, O43505 (See protein sequence)
Recommended Name: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase  
Size: 415 amino acids; 47119 Da
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein
Secondary accessions: Q4TTN0

Explore the universe of human proteins at neXtProt for B3GNT1: NX_O43505

Explore proteomics data for B3GNT1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O43505

  • 4/5 DME Specific Peptides for B3GNT1 (O43505) (see all 5)
     ALVVPAFE  SYPNNLLRNLARE  NKILYRQFKQELKA  QYFEFFPPSPRSVDQVK 

    B3GNT1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    B3GNT1 Protein Expression
    REFSEQ proteins: NP_006867.1  
    ENSEMBL proteins: 
     ENSP00000309096  
    Reactome Protein details: O43505
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    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0030173integral to Golgi membrane NAS9405606

    B3GNT1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    B3GT: Beta 3-glycosyltransferases

    1 InterPro protein domain:
     IPR026603 N-AclacN_B-1_3-N-AclacNTrfase

    Graphical View of Domain Structure for InterPro Entry O43505

    ProtoNet protein and cluster: O43505


    B3GNT1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: B3GN1_HUMAN, O43505
    Function: Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans
    Catalytic activity: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R = UDP +
    N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R

         Enzyme Number (IUBMB): EC 2.4.1.1491 2

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008532N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity IDA9405606
         
    B3GNT1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for B3GNT1:
     Increased cell number in G1, a 

         7 MGI mutant phenotypes (inferred from 3 alleles(MGI details for B3gnt1):
     behavior/neurological  cellular  immune system  mortality/aging  muscle 
     nervous system  other 

    B3GNT1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for B3GNT1: B3gnt1tm1Mifu B3gnt1tm1(KOMP)Vlcg

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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for B3GNT1 About                                                                                                See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Keratan sulfate biosynthesis
    Keratan sulfate biosynthesis0.82
    Glycosaminoglycan biosynthesis - keratan sulfate0.43
    Keratan sulfate/keratin metabolism0.82
    2Metabolism
    Metabolism0.40
    Metabolic pathways0.40
    3MPS IIIC - Sanfilippo syndrome C
    MPS IIIC - Sanfilippo syndrome C0.48
    Glycosaminoglycan metabolism0.48
    MPS IV - Morquio syndrome A0.48
    MPS IIID - Sanfilippo syndrome D0.48
    MPS VI - Maroteaux-Lamy syndrome0.48
    MPS I - Hurler syndrome0.48
    MPS IV - Morquio syndrome B0.48
    MPS IX - Natowicz syndrome0.48
    4Glycosphingolipid biosynthesis - lacto and neolacto series
    Glycosphingolipid biosynthesis - lacto and neolacto series
    5Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    5/18        Reactome Pathways for B3GNT1 (see all 18)
        MPS VI - Maroteaux-Lamy syndrome
    Metabolism
    Disease
    Keratan sulfate/keratin metabolism
    MPS II - Hunter syndrome


    3         Kegg Pathways  (Kegg details for B3GNT1):
        Glycosaminoglycan biosynthesis - keratan sulfate
    Glycosphingolipid biosynthesis - lacto and neolacto series
    Metabolic pathways

    UniProtKB/Swiss-Prot: B3GN1_HUMAN, O43505
    Pathway: Protein modification; protein glycosylation


    B3GNT1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for B3GNT1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    5/17 Interacting proteins for B3GNT1 (O435053 ENSP000003090964) via UniProtKB, MINT, STRING, and/or I2D (see all 17)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    STK3Q131883I2D: score=3 
    B3GNT3ENSP000003218744STRING: ENSP00000321874
    B3GNT4ENSP000003196364STRING: ENSP00000319636
    B4GALT1ENSP000003690554STRING: ENSP00000369055
    B4GALT2ENSP000003492934STRING: ENSP00000349293
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006486protein glycosylation IEA--
    GO:0018146keratan sulfate biosynthetic process TAS--
    GO:0030203glycosaminoglycan metabolic process TAS--
    GO:0030311poly-N-acetyllactosamine biosynthetic process IDA9405606

    B3GNT1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    B3GNT1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for B3GNT1 (B3GN1)

    3 HMDB Compounds for B3GNT1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Poly-N-acetyllactosaminePoly(N-acetyllactosamine) (see all 6)82441-98-3--
    Uridine 5'-diphosphate5'-UDP (see all 9)58-98-0--
    Uridine diphosphate-N-acetylglucosamineN-[2-[[[5-[(2,4-dioxo-1H-pyrimidin-1-yl)]-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphinoyl]oxy-hydroxy-phosphinoyl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-3-yl]acetamide (see all 30)528-04-1--

    1 Novoseek inferred chemical compound relationship for B3GNT1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    n-acetyllactosamine 91 10 10358011 (2), 10747980 (2), 9405606 (2), 8262950 (1) (see all 5)

    Search CenterWatch for drugs/clinical trials and news about B3GNT1 / B3GN1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for B3GNT1 gene: 
    NM_006876.2  

    Unigene Cluster for B3GNT1:

    UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
    Hs.8526  [show with all ESTs]
    Unigene Representative Sequence: NM_006876
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000311181(uc001ohr.3)
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    Additional mRNA sequence: 

    AF029893.1 AK075354.1 AK098389.1 AK098779.1 AK225182.1 AK293715.1 AK294604.1 BC021965.2 

    7 DOTS entries:

    DT.100796520  DT.454471  DT.95155593  DT.120734106  DT.120734094  DT.120734111  DT.97844419 

    24/289 AceView cDNA sequences (see all 289):

    BP379393 CB128751 BU846180 CR602074 AI085597 N93583 BQ881961 BQ128183 
    BM833520 BG152429 BM504639 AA382969 BU730048 AI300634 BQ072231 BF195700 
    BC021965 BF475788 CK822463 AK075354 CB265649 AW264293 AF029893 CF455359 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    B3GNT1 expression in normal human tissues (normalized intensities)      B3GNT1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGTGACAGCC
    B3GNT1 Expression
    About this image


    B3GNT1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 4 entries
             Metencephalon
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Midbrain tegmentum
             brain/hindbrain   
     
     Peripheral Nervous System (Nervous System)
             spinal/ganglion/dorsal root ganglion   
     
     Spinal Cord (Nervous System)
             spinal/ganglion/dorsal root ganglion   

     -- (Nervous System)
             mouse/organ system/nervous system/central nervous system   

    See B3GNT1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for B3GNT1

    SOURCE GeneReport for Unigene cluster: Hs.8526

    UniProtKB/Swiss-Prot: B3GN1_HUMAN, O43505
    Tissue specificity: In the adult, highly expressed in heart, brain, skeletal muscle and kidney and to a lesser
    extent in placenta, pancreas, spleen, prostate, testis, ovary, small intestine and colon. Very weak expression in
    lung, liver, thymus and peripheral blood leukocytes. In fetal highly expressed in brain and kidney and to a
    lesser extent in lung and liver

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for B3GNT1 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia B3gnt11 , 5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase more1, 5 88.67(n)1
    96.63(a)1
      19 (4.23 cM)5
    1089021  NM_175383.21  NP_780592.11 
     50388265 
    lizard
    (Anolis carolinensis)
    Reptilia B3GNT16
    Uncharacterized protein
    54(a)
    1 ↔ 1
    GL343890.1(1260-3826)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.56192 Transcribed sequence with weak similarity to protein more 72.39(n)    BQ526697.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5644501 n-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase-like 57.07(n)
    53.41(a)
      564450  XM_703369.4  XP_708461.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG32531 CG3253 43.99(n)
    32.29(a)
      37861  NM_138042.3  NP_611886.1 


    ENSEMBL Gene Tree for B3GNT1 (if available)
    TreeFam Gene Tree for B3GNT1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for B3GNT1 gene
    LARGE2  GYLTL1B2  

    B3GNT1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/111 SNPs in B3GNT1 are shown (see all 111)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1438067491,2
    --62437702(+) GACTGC/GAGCCT 1 -- ds50010--------
    rs115379921,2
    C--62437758(-) GCAGCC/TGGTAC 1 -- ds50012Minor allele frequency- T:0.00NA 4
    rs22984671,2
    C,H--62437760(+) ACCGGC/ATGCTG 1 -- ds50015Minor allele frequency- A:0.02EA NS 1906
    rs11906241,2
    C,F,H--62437822(-) CACCGA/CTAGGC 1 -- ds500114Minor allele frequency- C:0.05NS EA NA WA 1568
    rs1828890431,2
    C--62437990(+) CTTTGA/CAGACG 1 -- ds50010--------
    rs796423051,2
    --62438172(+) ATCTCA/GGGCTG 1 -- ut310--------
    rs1868526951,2
    --62438274(+) GCTAAG/TAACTA 1 -- ut310--------
    rs1917351081,2
    --62438305(+) TTTCTC/TTCCAA 1 -- ut310--------
    rs1452707311,2
    C--62438401(+) ATAAT-/AACAATAA 1 -- cds10--------
    rs1821043411,2
    --62438446(+) TACTTC/GACATT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for B3GNT1 (66112843 - 66115163 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for B3GNT1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv897783CNV Loss21882294
    nsv897772CNV Loss21882294
    dgv1187n71CNV Loss21882294
    dgv1190n71CNV Loss21882294
    dgv1189n71CNV Loss21882294


    Human Gene Mutation Database (HGMD): B3GNT1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing B3GNT1
    DNA2.0 Custom Variant and Variant Library Synthesis for B3GNT1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605517    OMIM disorders: --

    6 diseases for B3GNT1:    About MalaCards
    kidney fibrosarcoma    fibrosarcoma    morquio syndrome b    colon adenocarcinoma
    adenocarcinoma    prostatitis


    B3GNT1 for disorders           About GeneDecksing


    Export disorders for B3GNT1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for B3GNT1 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with B3GNT1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Expression cloning of cDNA encoding a human beta-1,3-N- acetylglucosaminyltransferase that is essential for poly-N- acetyllactosamine synthesis. (PubMed id 9405606)1, 2, 3, 9 Sasaki K.... Fukuda M. (1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Protein phosphatase 1g isoforms linked interactions in the brain. (PubMed id 23080069)1 Esteves S.L....da Cruz e Silva E.F. (2013)
    4. Brain transcriptome-wide screen for HIV-1 Nef protein interaction partners reveals various membrane-associated proteins. (PubMed id 23284715)1 Kammula E.C....Willbold D. (2012)
    5. Large-scale genome-wide association analysis of bipol ar disorder identifies a new susceptibility locus near ODZ4. (PubMed id 21926972)1 Sklar P....Purcell S.M. (2011)
    6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    7. Tumor suppressor function of laminin-binding alpha-dy stroglycan requires a distinct beta3-N-acetylglucosaminyltransferase. (PubMed id 19587235)1 Bao X....Fukuda M. (2009)
    8. Association of beta-1,3-N-acetylglucosaminyltransferase 1 and beta-1,4-galactosyltransferase 1, trans-Golgi enzymes involved in coupled poly-N-acetyllactosamine synthesis. (PubMed id 19261593)1 Lee P.L....Pfeffer S.R. (2009)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1 Otsuki T....Isogai T. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11041 HGNC: 15685 AceView: B3GNT6 Ensembl:ENSG00000174684 euGenes: HUgn11041
    ECgene: B3GNT1 Kegg: 11041 H-InvDB: B3GNT1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for B3GNT1 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/
    SeattleSNPshttp://pga.gs.washington.edu/data/b3gnt6/
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_547

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for B3GNT1 gene:
    Search GeneIP for patents involving B3GNT1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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