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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

B3GNT1 Gene

protein-coding   GIFtS: 53
GCID: GC11M066112

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase...

(Previous name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase...)
(Previous symbol: B3GNT6)
 Explore 5 diseases affiliated with
B3GNT1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for B3GNT1    

Aliases
for B3GNT1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 11 2 3     Poly-N-Acetyllactosamine Extension Enzyme2 3
B3GNT61 2 3     EC 2.4.1.1493 8
B3GN-T11 2     Beta-1,3-N-Acetylglucosaminyltransferase BGnT-62
BETA3GNTI1 2     I-Beta-1,3-N-Acetylglucosaminyltransferase1
IGAT5     N-Acetyllactosaminide Beta-1,3-N-Acetylglucosaminyltransferase2
IGNT5     I-Beta-1,3-N-Acetylglucosaminyltransferase1
UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 61 2     IGAT5
IGnT1     IGNT5

External Ids:    HGNC: 156851   Entrez Gene: 110412   Ensembl: ENSG000001746847   OMIM: 6055175   UniProtKB: O435053   

Export aliases for B3GNT1 gene to outside databases

Previous GC identifers: GC02P062551 GC02P062609 GC02P062380 GC02P062397 GC02P062334 GC11M065870


Summaries
for B3GNT1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for B3GNT1:
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II
transmembrane protein. It is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood
group i antigen. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: B3GN1_HUMAN, O43505
Function: Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans

Gene Wiki entry for B3GNT1


Genomic Views
for B3GNT1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the B3GNT1 gene promoter:
         AP-1   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: B3GNT1 promoter sequence
   Search SABiosciences Chromatin IP Primers for B3GNT1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B3GNT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.2   Ensembl cytogenetic band:  11q13.2   HGNC cytogenetic band: 11q13.2

B3GNT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B3GNT1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M066112:  view genomic region     (about GC identifiers)

Start:
 66,112,843 bp from pter      End:
 66,115,163 bp from pter
Size:
 2,321 bases      Orientation:
 minus strand

Proteins
for B3GNT1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: B3GN1_HUMAN, O43505 (See protein sequence)
Recommended Name: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase  
Size: 415 amino acids; 47119 Da
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein
Secondary accessions: Q4TTN0

Explore the universe of human proteins at neXtProt for B3GNT1: NX_O43505

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O43505

    • 4/5 DME Specific Peptides for B3GNT1 (O43505) (see all 5)
     ALVVPAFE  SYPNNLLRNLARE  NKILYRQFKQELKA  QYFEFFPPSPRSVDQVK 

    B3GNT1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006867.1  
    ENSEMBL proteins: 
     ENSP00000309096  
    Reactome Protein details: O43505
    Human Recombinant Protein Products: 
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    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0030173integral to Golgi membrane NAS9405606


    B3GNT1 for ontologies           About GeneDecksing



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    Browse ELISAs and CLIAs at Uscn

    Protein Domains /
    Families
    for B3GNT1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    B3GNT1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR026603 N-AclacN_B-1_3-N-AclacNTrfase

    Graphical View of Domain Structure for InterPro Entry O43505

    ProtoNet protein and cluster: O43505


    Function
    for B3GNT1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: B3GN1_HUMAN, O43505
    Function: Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans
    Catalytic activity: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R = UDP +
    N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R

    Enzyme Number (IUBMB): EC 2.4.1.1491 2

    miRNA
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    8/39 QIAGEN miScript miRNA Assays for microRNAs that regulate B3GNT1 (see all 39):
    hsa-miR-140-5p hsa-miR-3607-3p hsa-miR-429 hsa-let-7d hsa-let-7g hsa-let-7a hsa-miR-23a hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmid: B3GNT1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for B3GNT1 (see all 7)
    OriGene shRNA RFP: B3GNT1
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for B3GNT1

    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008532N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity IDA9405606
    GO:0016757transferase activity, transferring glycosyl groups ----


    B3GNT1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for B3GNT1:
     Increased cell number in G1, a 

    Animal Models:
         Mouse knock-out B3gnt1tm1Mifu for B3GNT1
         2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for B3gnt1):
     cellular  immune system 

    B3GNT1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for B3GNT1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1MPS IIIC - Sanfilippo syndrome C
    8/14 pathways (see all 14)
    		MPS IIIC - Sanfilippo syndrome C1.00
    		MPS IIIA - Sanfilippo syndrome A1.00
    		MPS I - Hurler syndrome1.00
    		MPS IIID - Sanfilippo syndrome D1.00
    		Mucopolysaccharidoses1.00
    		MPS IX - Natowicz syndrome1.00
    		MPS IV - Morquio syndrome A1.00
    		MPS II - Hunter syndrome1.00
    2Keratan sulfate biosynthesis
    		Keratan sulfate biosynthesis1.00
    		Glycosaminoglycan biosynthesis - keratan sulfate0.45
    		Keratan sulfate/keratin metabolism0.84
    3Metabolism
    		Metabolism1.00
    		Metabolic pathways0.38
    4Disease
    		Disease1.00
    5Glycosphingolipid biosynthesis - lacto and neolacto series
    		Glycosphingolipid biosynthesis - lacto and neolacto series1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/18        Reactome Pathways for B3GNT1 (see all 18)
        MPS VI - Maroteaux-Lamy syndrome
    Metabolism
    Disease
    Keratan sulfate/keratin metabolism
    MPS II - Hunter syndrome


    3         Kegg Pathways  (Kegg details for B3GNT1):
        Glycosaminoglycan biosynthesis - keratan sulfate
    Glycosphingolipid biosynthesis - lacto and neolacto series
    Metabolic pathways

    UniProtKB/Swiss-Prot: B3GN1_HUMAN, O43505
    Pathway: Protein modification; protein glycosylation


    B3GNT1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for B3GNT1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    5/17 Interacting proteins for B3GNT1 (O435053 ENSP000003090964) via UniProtKB, MINT, STRING, and/or I2D (see all 17)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    STK3Q131883I2D: score=3 
    B3GNT3ENSP000003218744STRING: ENSP00000321874
    B3GNT4ENSP000003196364STRING: ENSP00000319636
    B4GALT1ENSP000003690554STRING: ENSP00000369055
    B4GALT2ENSP000003492934STRING: ENSP00000349293
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006486protein glycosylation IEA--
    GO:0018146keratan sulfate biosynthetic process TAS--
    GO:0030203glycosaminoglycan metabolic process TAS--
    GO:0030311poly-N-acetyllactosamine biosynthetic process IDA9405606


    B3GNT1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for B3GNT1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    B3GNT1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for B3GNT1

    3 HMDB Compounds for B3GNT1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Poly-N-acetyllactosaminePoly(N-acetyllactosamine) (see all 6)82441-98-3--
    Uridine 5'-diphosphate5'-UDP (see all 9)58-98-0--
    Uridine diphosphate-N-acetylglucosamineN-[2-[[[5-[(2,4-dioxo-1H-pyrimidin-1-yl)]-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphinoyl]oxy-hydroxy-phosphinoyl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-3-yl]acetamide (see all 30)528-04-1--
    1 Novoseek chemical compound relationship for B3GNT1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    n-acetyllactosamine 91 10 10358011 (2), 10747980 (2), 9405606 (2), 8262950 (1) (see all 5)

    Search CenterWatch for drugs/clinical trials and news about B3GNT1 / B3GN1 

    Transcripts
    for B3GNT1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for B3GNT1 gene: 
    NM_006876.2  

    Unigene Cluster for B3GNT1:

    UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
    Hs.8526  [show with all ESTs]
    Unigene Representative Sequence: NM_006876
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000311181(uc001ohr.3)

    miRNA
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    8/39 QIAGEN miScript miRNA Assays for microRNAs that regulate B3GNT1 (see all 39):
    hsa-miR-140-5p hsa-miR-3607-3p hsa-miR-429 hsa-let-7d hsa-let-7g hsa-let-7a hsa-miR-23a hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmid: B3GNT1 3' UTR sequence
    Inhib. RNA
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AF029893.1 AK075354.1 AK098389.1 AK098779.1 AK225182.1 AK293715.1 AK294604.1 BC021965.2 

    7 DOTS entries:

    DT.100796520  DT.454471  DT.95155593  DT.120734106  DT.120734094  DT.120734111  DT.97844419 

    24/289 AceView cDNA sequences (see all 289):

    AF029893 AI300634 BQ128183 T08639 BQ881961 BM704157 BF475788 CA425392 
    AI186969 CF455359 BU848688 BU622411 BM926886 CR623114 BU730048 BM975403 
    CR602074 BF195700 CB265649 AA431893 BU846180 AA382969 BP379393 BQ581439 

    GeneLoc Exon Structure


    Expression
    for B3GNT1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    B3GNT1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGTGACAGCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    B3GNT1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    5 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Spinal CordSpinal Dorsal ColumnsDorsal Spinal Cord Progenitor CellsSpinal Cord
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    Neural TubeDiencephalic Ventricular ZoneNeural Tube
    Spinal CordSpinal Dorsal ColumnsSpinal Cord
    Spinal CordSpinal Ventral ColumnsSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See B3GNT1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for B3GNT1

    SOURCE GeneReport for Unigene cluster: Hs.8526

    UniProtKB/Swiss-Prot: B3GN1_HUMAN, O43505
    Tissue specificity: In the adult, highly expressed in heart, brain, skeletal muscle and kidney and to a lesser extent
    in placenta, pancreas, spleen, prostate, testis, ovary, small intestine and colon. Very weak expression in lung,
    liver, thymus and peripheral blood leukocytes. In fetal highly expressed in brain and kidney and to a lesser extent in
    lung and liver

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    In Situ
    Assay Products:     
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    Orthologs
    for B3GNT1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for B3GNT1 gene from 4/19 species (see all 19)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    lizard
    (Anolis carolinensis)    		 Reptilia B3GNT16
    		 --
    		 54(a)
    		 1 ↔ 1
    		 GL343890.1(1260-3826)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.56192 Transcribed sequence with weak similarity to protein more 72.39(n)    BQ526697.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii LOC5644501 n-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase-like 57.07(n)
    53.41(a)    		   564450  XM_703369.4  XP_708461.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG32531 CG3253 43.99(n)
    32.29(a)    		   37861  NM_138042.3  NP_611886.1 


    ENSEMBL Gene Tree for B3GNT1 (if available)
    TreeFam Gene Tree for B3GNT1 (if available) 

    Paralogs
    for B3GNT1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for B3GNT1 gene
    LARGE2  GYLTL1B2  

    B3GNT1 for paralogs           About GeneDecksing



    Genomic Variants
    for B3GNT1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/80 NCBI SNPs in B3GNT1 are shown (see all 80)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 11 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1438067491,2
    		--66112454(+) GACTGC/GAGCCT 3 -- ds5001 ut510--------
    rs115379921,2
    		C--66112510(-) GCAGCC/TGGTAC 3 -- ds5001 ut512Minor allele frequency- T:0.00NA 4
    rs22984671,2
    		C,H--66112512(+) ACCGGC/ATGCTG 3 -- ds5001 ut515Minor allele frequency- A:0.02EA NS 1906
    rs11906241,2
    		C,F,H,--66112574(-) CACCGA/CTAGGC 3 -- ds5001 ut5114Minor allele frequency- C:0.05NS EA NA WA 1568
    rs1828890431,2
    		--66112742(+) CTTTGA/CAGACG 3 -- ds5001 us2k10--------
    rs796423051,2
    		--66112924(+) ATCTCA/GGGCTG 3 -- ut31 us2k10--------
    rs1868526951,2
    		--66113026(+) GCTAAG/TAACTA 3 -- ut31 us2k10--------
    rs1917351081,2
    		--66113057(+) TTTCTC/TTCCAA 3 -- ut31 us2k10--------
    rs1452707311,2
    		C,--66113153(+) ATAAT-/AACAATAA 3 -- us2k1 ut310--------
    rs1821043411,2
    		--66113198(+) TACTTC/GACATT 3 -- us2k1 ut310--------

    HapMap Linkage Disequilibrium report for B3GNT1 (66112843 - 66115163 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for B3GNT1: --
    Human Gene Mutation Database (HGMD): B3GNT1

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for B3GNT1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    B3GNT1 for disorders           About GeneDecksing

    OMIM gene information: 605517    OMIM disorders: --

    5 diseases for B3GNT1:    About MalaCards
    kidney fibrosarcoma    fibrosarcoma    colon adenocarcinoma    adenocarcinoma
    prostatitis


    Export disorders for B3GNT1 gene to outside databases

    Publications
    for B3GNT1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for B3GNT1 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with B3GNT1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Expression cloning of cDNA encoding a human beta-1,3-N- acetylglucosaminyltransferase that is essential for poly-N- acetyllactosamine synthesis. (PubMed id 9405606)1, 2, 3, 9 Sasaki K.... Fukuda M. (1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Large-scale genome-wide association analysis of bipol ar disorder identifies a new susceptibility locus near ODZ4. (PubMed id 21926972)1 Sklar P....Purcell S.M. (2011)
    4. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    5. Tumor suppressor function of laminin-binding alpha-dy stroglycan requires a distinct beta3-N-acetylglucosaminyltransferase. (PubMed id 19587235)1 Bao X....Fukuda M. (2009)
    6. Association of beta-1,3-N-acetylglucosaminyltransferase 1 and beta-1,4-galactosyltransferase 1, trans-Golgi enzymes involved in coupled poly-N-acetyllactosamine synthesis. (PubMed id 19261593)1 Lee P.L....Pfeffer S.R. (2009)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    8. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1 Otsuki T....Isogai T. (2005)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)

    External Searches for B3GNT1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing B3GNT1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11041 HGNC: 15685 AceView: B3GNT6 Ensembl:ENSG00000174684 euGenes: HUgn11041
    ECgene: B3GNT1 Kegg: 11041 H-InvDB: B3GNT1

    Other Databases showing B3GNT1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing B3GNT1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for B3GNT1 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/
    SeattleSNPshttp://pga.gs.washington.edu/data/b3gnt6/
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_547

    Intellectual Property
    for B3GNT1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for B3GNT1 gene:
    Search GeneIP for patents involving B3GNT1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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