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B3GAT3 Gene

protein-coding GIFtS: 59

GC11M062139

beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
EC 2.4.1.135 ^³
GLCATI ^², ⁵
GlcAT-I ^¹, ³
GlcUAT-I ^³
Glucuronosyltransferase-I ^³

Descriptions
Beta-1,3-glucuronyltransferase 3 ^², ³
Sqv-8-like protein ^²
UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase ^³
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) ^²
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase ^²
glucuronosyltransferase I ^²

External Ids
HGNC: 923¹
Entrez Gene: 26229²
UniProtKB: O94766³
Ensembl: ENSG00000149541⁷

Search outside databases for aliases for B3GAT3 gene

Previous GC identifers: GC11M064895 GC11M063958 GC11M062633 GC11M062158

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for B3GAT3:

The protein encoded by this gene is a member of the glucuronyltransferase gene family, enzymes that

exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric

linkages. This gene product catalyzes the formation of the glycosaminoglycan-protein linkage by

way of a glucuronyl transfer reaction in the final step of the biosynthesis of the linkage region

of proteoglycans. [provided by RefSeq]

UniProtKB/Swiss-Prot: B3GA3_HUMAN, O94766

Function: Glycosaminoglycans biosynthesis. Involved in forming the linkage tetrasaccharide present

in heparan sulfate and chondroitin sulfate. Transfers a glucuronic acid moiety from the uridine

diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide

Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan

attachment site of proteoglycans. Can also play a role in the biosynthesis of l2/HNK-1

carbohydrate epitope on glycoproteins. Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl,

exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal

beta1-O-benzyl, Galbeta1-4GlcNAc and Galbeta1-4Glc

Gene Wiki entry for B3GAT3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the B3GAT3 gene

Entrez Gene cytogenetic band: 11q12.3 Ensembl cytogenetic band: 11q12.3 HGNC cytogenetic band: 11q12

B3GAT3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M062139: (about GC identifiers)

Start:	62,139,344 bp from pter
End:	62,146,024 bp from pter
Size:	6,681 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000011.8 NT_033903.7

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: B3GA3_HUMAN, O94766 (See protein sequence)

Recommended Name: Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

Size: 335 amino acids; 37122 Da

Cofactor: Manganese

Subunit: Homodimer; disulfide-linked

Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein

PDB structures from and Proteopedia :

1FGG (3D)

1KWS (3D)

3CU0 (3D)

Secondary accessions: Q96I06 Q9UEP0

Post-translational modifications:

N-glycosylated¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_036332.2

ENSEMBL proteins:

ENSP00000265471

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (B3GAT3)
	Human Recombinant Proteins from Abnova (B3GAT3)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	NAS	--
GO:0005794	Golgi apparatus	IEA	--
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	NAS	10842173

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Antibodies for B3GAT3:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for B3GAT3
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (B3GAT3), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (B3GAT3)
	Novus Biologicals Antibodies for B3GAT3

Assays for B3GAT3:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry O94766

ProtoNet protein and cluster: O94766

1 Blocks protein family: IPB005027 Glycosyl transferase

UniProtKB/Swiss-Prot: B3GA3_HUMAN, O94766

Similarity: Belongs to the glycosyltransferase 43 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Browse Invitrogen for RNAi
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (B3GAT3)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012200

Applied Biosystems Silencer® siRNAs for B3GAT3

Sigma-Aldrich siRNA for B3GAT3

Sigma-Aldrich shRNA for B3GAT3

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for B3GAT3
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_012200
Myc/DDK tagged cDNA clone in CMV expression vector: NM_012200
untagged cDNA clone in CMV expression vector: NM_012200

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_012200

UniProtKB/Swiss-Prot: B3GA3_HUMAN, O94766

Function: Glycosaminoglycans biosynthesis. Involved in forming the linkage tetrasaccharide present

in heparan sulfate and chondroitin sulfate. Transfers a glucuronic acid moiety from the uridine

diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide

Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan

attachment site of proteoglycans. Can also play a role in the biosynthesis of l2/HNK-1

carbohydrate epitope on glycoproteins. Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl,

exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal

beta1-O-benzyl, Galbeta1-4GlcNAc and Galbeta1-4Glc

Catalytic activity: UDP-glucuronate +

3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP +

3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein

Enzyme regulation: Inhibited by EDTA

Enzyme Number (IUBMB): EC 2.4.1.135

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity	NAS	10842173
GO:0016740	transferase activity	IEA	--
GO:0030145	manganese ion binding	NAS	--
GO:0046872	metal ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for B3GAT3 (Your Favorite Gene powered by Ingenuity)

Chondroitin Sulfate Biosynthesis

GeneDecks B3GAT3 for the pathways selected above

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UniProtKB/Swiss-Prot: B3GA3_HUMAN, O94766

Pathway: Protein modification; protein glycosylation

5/7 Interacting proteins for B3GAT3 (ENSP00000265471³) via UniProtKB, MINT, and/or STRING (see all 7 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CSGALNACT1	ENSP00000330805³	STRING (score=.899)
CSGALNACT2	ENSP00000363590³	STRING (score=.899)
B3GAT1	ENSP00000307875³	STRING (score=.814)
B3GAT2	ENSP00000230053³	STRING (score=.811)
EXTL2	ENSP00000359132³	STRING (score=.808)

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1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006024	glycosaminoglycan biosynthetic process	NAS	10842173

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for B3GAT3
7 Novoseek chemical compound relationships for B3GAT3 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
glycosaminoglycan	81.31	10	15601778 (4), 11535117 (1), 15522873 (1), 16815917 (1) (see all 5)
udp glucuronic acid	79.35	3	16815917 (1), 10946001 (1)
tetrasaccharide	79.03	2	12794088 (1), 16807373 (1)
gal 1	70.55	5	17567734 (2), 15522873 (1)
heparan sulfate	56.60	1	16807373 (1)
ribose	55.91	1	12794088 (1)
galactose	36.72	2	16300963 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Browse Invitrogen for RNAi
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (B3GAT3)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012200

Sigma-Aldrich siRNA for B3GAT3

Sigma-Aldrich shRNA for B3GAT3

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_012200

REFSEQ mRNAs for B3GAT3 gene:

NM_012200.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_012200

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_012200
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_012200
                                 untagged cDNA clone in CMV expression vector: NM_012200

Additional cDNA sequence:

AB009598.1 AJ005865.1 AK075166.1 AK297970.1 AK310200.1 AK316228.1 BC007906.2 BC011173.1

BC019832.1 BC071961.1 CR591171.1 CR592820.1 CR593367.1 CR596079.1 CR598262.1 CR598436.1

CR608174.1 CR609724.1 CR622950.1 CR625454.1

11 DOTS entries:

DT.97818666 DT.97855455 DT.97855456 DT.100038261 DT.101977214 DT.120727985 DT.100796527 DT.120727994

DT.120858477 DT.120858512 DT.91858934

24/90 AceView cDNA sequences (see all 90 ):

BM675957 BM726069 BM673426 BQ012133 BF509647 CD369583 BM055157 BU501433

CK904815 BF514497 BF223289 AI198078 CD364443 BM728084 AL577678 CK904816

BM707304 AW236575 CD106839 BG394975 BM712432 AL536981 AL578024 AW268136

highest scoring ESTs for B3GAT3:

AB009598 AJ005865 AK075166 AL519604 AL529274 AL533075 AL541839 AL556950 BC007906 BC019832

Unigene Cluster for B3GAT3:

Beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)

Hs.502759 [show with all ESTs]

Unigene Representative Sequence: AK075166

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for B3GAT3 (see all 7 )

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	^	3a	·	3b	·	3c	^	4a	·	4b	·	4c	^	5	^	6	^	7
SP1:
SP2:
SP3:																											-
SP4:
SP5:									-

About this scheme

ECgene alternative splicing isoforms for B3GAT3

1 Ensembl transcript including schematic representation:

ENST00000265471

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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B3GAT3 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for B3GAT3

¹ / ² / ³

5 probe-sets matching B3GAT3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
35179_at²^{, 3}	U133-A	2	1.00	0.97	1.00	1.00	AB009598	1.00	1.00	1.00	1
203452_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_012200	0.60	1.00	0.82	1
35179_at²^{, 3}	U133-A	2	1.00	0.97	--	--	AB009598	1.00	1.00	1.00	1
203452_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
35179_at²	U133Plus2	2	1.00	0.97	--	--	--	--	--	--	--

GeneDecks B3GAT3 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CTGACCCCCT

SOURCE GeneReport for Unigene cluster: Hs.502759
Expression variation in blood from EXPOLDB for B3GAT3
UniProtKB/Swiss-Prot: B3GA3_HUMAN, O94766
Tissue specificity: Ubiquitous (but weakly expressed in all tissues examined)

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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Orthologs for B3GAT3 gene from 5/10 species (see all 10 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	B3GAT3¹	--	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase more	91.84(n) 96.12(a)	483785 XM_540906.2 XP_540906.2
chimpanzee (Pan troglodytes)	B3GAT3¹	--	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase more	90.75(n) 86.86(a)	740388 XM_001142393.1 XP_001142393.1
cow (Bos taurus)	B3GAT3¹	--	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase more	91.54(n) 95.52(a)	404162 NM_205805.2 NP_991374.2
mouse (Mus musculus)	B3gat3^{1, 5}	19⁵	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase more^{1, 5}	88.16(n)¹ 95.82(a)¹	72727¹ NM_024256.2¹ NP_077218.1¹ AI835481⁵ AK048428⁵ (see all 17)
zebrafish (Danio rerio)	b3gat3¹	--	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase more	63.8(n) 60.43(a)	192334 NM_001015059.1 NP_001015059.1

About this table Species with no ortholog for B3GAT3

ENSEMBL Gene Tree for B3GAT3

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
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Paralogs for B3GAT3 gene

B3GAT1² B3GAT2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
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10/39 NCBI SNPs in B3GAT3 are shown (see all 39 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 21)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs4343028^1,2	A,C	62146194(+)	`CACCCC/TCCCGC`	1	--	ng3¹		0	--	--	--	--
	rs4963224^1,2	C,F,H	62141445(+)	`TTGCCC/TGCTCC`	1	--	int¹		4		EU EA WA	418
--	rs4264155^1,2	A,C	62143798(+)	`tgttgC/Tccagg`	1	--	int¹		0	--	--	--	--
	rs11231164^1,2	C,H	62144838(+)	`ccttaT/Cgactt`	1	--	int¹		4		EU EA WA	418
--	rs10897288^1,2	A,C	62143048(+)	`AAAAAA/TATTAG`	1	--	int¹ trp³		0	--	--	--	--
	rs11231165^1,2	C,H	62144995(+)	`gccttC/TtggGC`	1	--	int¹		4		EU EA WA	414
--	rs12808971^1,2	H	62143782(+)	`gacaaG/Aagttt`	1	--	int¹		4		EU EA WA	420
--	rs11827317^1,2	C	62142565(+)	`attagC/Ttgggt`	1	--	int¹		0	--	--	--	--
--	rs7122950^1,2	C	62141944(+)	`aaaggC/Tcgggc`	1	--	int¹		0	--	--	--	--
--	rs550395^1,2	--	62147242(+)	`caggtA/Ggatca`	1	--	ng3¹		0	--	--	--	--

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HapMap Linkage Disequilibrium images for B3GAT3 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 606374

(Possibly Related Articles in Doctor's Guide)
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(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/21 PubMed articles for B3GAT3 gene (see all 21 ):

Molecular cloning and expression of glucuronyltransferase I involved in the biosynthesis of the glycosaminoglycan-protein linkage region of proteoglycans. (PubMed id 9506957)^{2, 3, 4} Kitagawa H.... Sugahara K. (1998)
Structure/function of the human Ga1beta1,3-glucuronosyltransferase. Dimerization and functional activity are mediated by two crucial cysteine residues. (PubMed id 10842173)^{1, 3, 4} Ouzzine M.... Fournel-Gigleux S. (2000)
Characterization of recombinant human glucuronyltransferase I involved in the biosynthesis of the glycosaminoglycan-protein linkage region of proteoglycans. (PubMed id 10526176)^{1, 3, 4} Tone Y.... Sugahara K. (1999)
Heparan/chondroitin sulfate biosynthesis. Structure and mechanism of human glucuronyltransferase I. (PubMed id 10946001)^{1, 3, 4} Pedersen L.C....Negishi M. (2000)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Three proteins involved in Caenorhabditis elegans vulval invagination are similar to components of a glycosylation pathway. (PubMed id 9927678)^{3, 4} Herman T. and Horvitz H.R. (1999)
Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: a strategy to promote cartilage repair. (PubMed id 15601778)^{1, 3} Venkatesan N....Ouzzine M. (2004)
Molecular basis for acceptor substrate specificity of the human beta1,3-glucuronosyltransferases GlcAT-I and GlcAT-P involved in glycosaminoglycan and HNK-1 carbohydrate epitope biosynthesis, respectively. (PubMed id 17567734)^{1, 3} Fondeur-Gelinotte M....Fournel-Gigleux S. (2007)
Human glycosaminoglycan glucuronyltransferase I gene and a related processed pseudogene: genomic structure, chromosomal mapping and characterization. (PubMed id 11535117)^{1, 3} Kitagawa H....Sugahara K. (2001)
The functional glycosyltransferase signature sequence of the human beta 1,3-glucuronosyltransferase is a XDD motif. (PubMed id 12794088)^{1, 3} Gulberti S....Ouzzine M. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 26229	HGNC: 923	AceView: B3GAT3	Ensembl:ENSG00000149541	euGenes: HUgn26229
ECgene: B3GAT3	H-InvDB: B3GAT3

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
GGDB	http://riodb.ibase.aist.go.jp/rcmg/ggdb/

Licensable Technologies for B3GAT3
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for B3GAT3:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for B3GAT3-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for B3GAT3		Antibodies for B3GAT3
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for B3GAT3		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Search OriGene for B3GAT3

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Antibodies for B3GAT3

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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B3GAT3 Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for B3GAT3

Summaries
for B3GAT3

Genomic Location
for B3GAT3

Proteins
for B3GAT3

Protein Domains/
Families
for B3GAT3

Gene Function
for B3GAT3

Pathways & Interactions
for B3GAT3

Drugs & Compounds
for B3GAT3

Transcripts
for B3GAT3

Expression
for B3GAT3

Orthologs
for B3GAT3

Paralogs
for B3GAT3

SNPs/Variants
for B3GAT3

Disorders & Mutations
for B3GAT3

Medical News
for B3GAT3

Publications
for B3GAT3

Search for B3GAT3

Genome Databases showing B3GAT3

Other Databases showing B3GAT3

Specialized Databases showing B3GAT3

Licensable Technologies
for B3GAT3

Services
for B3GAT3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

B3GAT3 Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor B3GAT3

Summariesfor B3GAT3

Genomic Locationfor B3GAT3

Proteinsfor B3GAT3

Protein Domains/Familiesfor B3GAT3

Gene Functionfor B3GAT3

Pathways & Interactionsfor B3GAT3

Drugs & Compoundsfor B3GAT3

Transcriptsfor B3GAT3

Expression for B3GAT3

Orthologsfor B3GAT3

Paralogsfor B3GAT3

SNPs/Variantsfor B3GAT3

Disorders & Mutationsfor B3GAT3

Medical Newsfor B3GAT3

Publicationsfor B3GAT3

Search for B3GAT3

Genome Databases showing B3GAT3

Other Databases showing B3GAT3

Specialized Databases showing B3GAT3

Licensable Technologiesfor B3GAT3

Servicesfor B3GAT3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for B3GAT3

Summaries
for B3GAT3

Genomic Location
for B3GAT3

Proteins
for B3GAT3

Protein Domains/
Families
for B3GAT3

Gene Function
for B3GAT3

Pathways & Interactions
for B3GAT3

Drugs & Compounds
for B3GAT3

Transcripts
for B3GAT3

Expression
for B3GAT3

Orthologs
for B3GAT3

Paralogs
for B3GAT3

SNPs/Variants
for B3GAT3

Disorders & Mutations
for B3GAT3

Medical News
for B3GAT3

Publications
for B3GAT3

Licensable Technologies
for B3GAT3

Services
for B3GAT3