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B3GAT2 Gene

protein-coding   GIFtS: 56
GCID: GC06M071566

Beta-1,3-Glucuronyltransferase 2 (Glucuronosyltransferase...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Beta-1,3-Glucuronyltransferase 2 (Glucuronosyltransferase S)1 2     glcAT-D2
GLCATS2 3 5     UDP-Glucuronyltransferase S2
Glucuronosyltransferase S2 3     Uridine Diphosphate Glucuronic Acid:Acceptor Glucuronosyltransferase2
UDP-Glucuronosyltransferase S2 3     GlcAT-D3
EC 2.4.1.1353 8     GlcAT-S3
KIAA19633 5     Beta-1,3-Glucuronyltransferase 23
Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 22     

External Ids:    HGNC: 9221   Entrez Gene: 1351522   Ensembl: ENSG000001123097   OMIM: 6074975   UniProtKB: Q9NPZ53   

Export aliases for B3GAT2 gene to outside databases

Previous GC identifers: GC00U990665 GC06M071533 GC06M071562 GC06M071623 GC06M068769


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for B3GAT2 Gene:
The product of this gene is a transmembrane protein belonging to the glucuronyltransferase family, and catalyzes
the transfer of a beta-1,3 linked glucuronic acid to a terminal galactose in different glycoproteins or
glycolipids containing a Gal-beta-1-4GlcNAc or Gal-beta-1-3GlcNAc residue. The encoded protein is involved in the
synthesis of the human natural killer-1 (HNK-1) carbohydrate epitope, a sulfated trisaccharide implicated in
cellular migration and adhesion in the nervous system. (provided by RefSeq, Jul 2008)

GeneCards Summary for B3GAT2 Gene:
B3GAT2 (beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)) is a protein-coding gene. GO annotations related to this gene include galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity. An important paralog of this gene is B3GAT1.

UniProtKB/Swiss-Prot: B3GA2_HUMAN, Q9NPZ5
Function: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins (By
similarity)

Gene Wiki entry for B3GAT2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the B3GAT2 gene promoter:
         AREB6   N-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidB3GAT2 promoter sequence
   Search Chromatin IP Primers for B3GAT2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat B3GAT2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q13   Ensembl cytogenetic band:  6q13   HGNC cytogenetic band: 6q12

B3GAT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B3GAT2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M071566:  view genomic region     (about GC identifiers)

Start:
71,566,382 bp from pter      End:
71,666,788 bp from pter
Size:
100,407 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: B3GA2_HUMAN, Q9NPZ5 (See protein sequence)
Recommended Name: Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2  
Size: 323 amino acids; 36919 Da
Cofactor: Manganese
Subunit: Homodimer (Potential)
Sequence caution: Sequence=BAB70889.1; Type=Erroneous initiation; Sequence=BAB85549.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for B3GAT2:
2D0J (3D)    
Secondary accessions: Q5JS09 Q8TF38 Q96NK4

Explore the universe of human proteins at neXtProt for B3GAT2: NX_Q9NPZ5

Explore proteomics data for B3GAT2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn67, Asn292
  • Selected DME Specific Peptides for B3GAT2 (Q9NPZ5) (see all 5)
     VWHTRTEK  VWPVGLVGG  RPFAIDMAGFAV  FADDDNTYSLELF 


    See B3GAT2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_542780.1  
    ENSEMBL proteins: 
     ENSP00000230053  
    Reactome Protein details: Q9NPZ5

    B3GAT2 Human Recombinant Protein Products:

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    Browse Proteins at Cloud-Clone Corp.

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    B3GAT: Beta-1,3-glucuronyltransferases

    1 InterPro protein domain:
     IPR005027 Glyco_trans_43

    Graphical View of Domain Structure for InterPro Entry Q9NPZ5

    ProtoNet protein and cluster: Q9NPZ5

    1 Blocks protein domain: IPB005027 Glycosyl transferase

    UniProtKB/Swiss-Prot: B3GA2_HUMAN, Q9NPZ5
    Similarity: Belongs to the glycosyltransferase 43 family


    Find genes that share domains with B3GAT2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: B3GA2_HUMAN, Q9NPZ5
    Function: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins (By
    similarity)
    Catalytic activity: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP +
    3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein

         Enzyme Number (IUBMB): EC 2.4.1.1351 2

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015018galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity ISS--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with B3GAT2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for B3GAT2:
     Increased viability after born 

    Animal Models:
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    miRNA
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    Inhib. RNA
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    Browse Sino Biological Human cDNA Clones
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    B3GA2_HUMAN, Q9NPZ5: Golgi apparatus membrane; Single-pass type II membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus5
    cytosol2
    endoplasmic reticulum2
    extracellular2
    nucleus2
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with B3GAT2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for B3GAT2 About   (see all 8)  
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1MPS VI - Maroteaux-Lamy syndrome
    MPS VI - Maroteaux-Lamy syndrome0.45
    MPS II - Hunter syndrome0.45
    MPS IIIC - Sanfilippo syndrome C0.45
    Glycosaminoglycan metabolism0.45
    MPS IV - Morquio syndrome A0.45
    MPS IV - Morquio syndrome B0.45
    Mucopolysaccharidoses0.45
    MPS VII - Sly syndrome0.45
    2Chondroitin sulfate/dermatan sulfate metabolism
    Chondroitin sulfate/dermatan sulfate metabolism0.51
    A tetrasaccharide linker sequence is required for GAG synthesis0.51
    3dermatan sulfate biosynthesis
    dermatan sulfate biosynthesis
    glycoaminoglycan-protein linkage region biosynthesis0.00
    4heparan sulfate biosynthesis
    heparan sulfate biosynthesis0.79
    5Heparan sulfate/heparin (HS-GAG) metabolism
    Heparan sulfate/heparin (HS-GAG) metabolism0.57


    Find genes that share SuperPaths with B3GAT2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4 BioSystems Pathways for B3GAT2
        glycoaminoglycan-protein linkage region biosynthesis
    heparan sulfate biosynthesis
    chondroitin sulfate biosynthesis
    dermatan sulfate biosynthesis

    1 Reactome Pathway for B3GAT2
        A tetrasaccharide linker sequence is required for GAG synthesis


    1 Kegg Pathway  (Kegg details for B3GAT2):
        Other types of O-glycan biosynthesis

    UniProtKB/Swiss-Prot: B3GA2_HUMAN, Q9NPZ5
    Pathway: Protein modification; protein glycosylation

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for B3GAT2
    Interactions:

        Search GeneGlobe Interaction Network for B3GAT2

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for B3GAT2 (ENSP000002300534) via UniProtKB, MINT, STRING, and/or I2D

    InteractantInteraction Details
    GeneCardExternal ID(s)
    B3GALT6ENSP000003684964STRING: ENSP00000368496
    CSGALNACT1ENSP000003108914STRING: ENSP00000310891
    CSGALNACT2ENSP000003635904STRING: ENSP00000363590
    EXTL2ENSP000003591314STRING: ENSP00000359131
    EXTL3ENSP000002205624STRING: ENSP00000220562
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006486protein glycosylation IEA--
    GO:0030203glycosaminoglycan metabolic process TAS--
    GO:0030204chondroitin sulfate metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    Find genes that share ontologies with B3GAT2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for B3GAT2 (B3GA2)

    3 HMDB Compounds for B3GAT2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Manganesemanganese 7439-96-5--
    Uridine 5'-diphosphate5'-UDP (see all 9)58-98-0--
    Uridine diphosphate glucuronic acidUDP glucuronate (see all 41)2616-64-0--

    2 Novoseek inferred chemical compound relationships for B3GAT2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    paragloboside 90.8 1 15470230 (1)
    glycolipid 68.2 1 15470230 (1)



    Find genes that share compounds with B3GAT2           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for B3GAT2 gene: 
    NM_080742.2  

    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000230053(uc003pfv.3 uc003pfw.3)
    miRNA
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      QuantiFast Probe-based Assays in human, mouse, rat B3GAT2

    Selected AceView cDNA sequences (see all 49):

    AY070019 BG149793 BM698655 NM_080742 BM693450 AW590323 F11751 AB075843 
    AI138778 BM670746 BF477827 R18896 BM674929 AU253732 Z38517 AW292462 
    AI701137 BI914787 BE550679 F09411 D25748 AI702728 AK055248 BE089137 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for B3GAT2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b
    SP1:                                    
    SP2:                                    


    ECgene alternative splicing isoforms for B3GAT2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    B3GAT2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTCTATAAGC
    B3GAT2 Expression
    About this image


    B3GAT2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Telencephalon
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Kidney (Urinary System)
             Metanephros
     
     Brain (Nervous System)
             Cerebellum
    B3GAT2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    B3GAT2 Protein Expression

    UniProtKB/Swiss-Prot: B3GA2_HUMAN, Q9NPZ5
    Tissue specificity: Expressed in the trachea, retina, spinal cord, hippocampus and other brain regions, and, at
    lower levels, in testis and ovary

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B3GAT2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for B3GAT2 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia B3gat21 , 5 beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase more1, 5 88.65(n)1
    90.71(a)1
      1 (9.75 cM)5
    2806451  NM_172124.21  NP_742122.21 
     237617535 
    chicken
    (Gallus gallus)
    Aves B3GAT21 beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase more 86.56(n)
    94.24(a)
      428638  NM_001031527.1  NP_001026698.1 
    lizard
    (Anolis carolinensis)
    Reptilia B3GAT26
    beta-1,3-glucuronyltransferase 2 (glucuronosyltran...
    77(a)
    1 ↔ 1
    1(167808812-167848701)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia b3gat21 beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase more 71.84(n)
    76.4(a)
      594928  NM_001030353.2  NP_001025524.1 
    zebrafish
    (Danio rerio)
    Actinopterygii AF506207.12   -- 73.84(n)   192334  AF506207.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta GlcAT-I6
    GlcAT-P6
    (see all 3)
    GlcAT-P
    (see all 3)
    43(a)
    23(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    X(4025250-4026866)
    3L(11170054-11190636)
    worm
    (Caenorhabditis elegans)
    Secernentea glct-16
    sqv-86
    (see all 7)
    Protein SQV-8 (sqv-8) mRNA, complete cds
    (see all 7)
    34(a)
    33(a)
    (see all 7)
    many ↔ many
    many ↔ many
    (see all 7)
    I(12337968-12339239) WBGene00011650
    II(9647938-9649224) WBGene00005026
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons IRX9-L1 IRX9-L 45.68(n)
    37.04(a)
      839652  NM_102525.2  NP_564290.2 
    rice
    (Oryza sativa)
    Liliopsida Os10g02053001 Os10g0205300 49.77(n)
    38.14(a)
      4348270  NM_001070845.1  NP_001064310.1 


    ENSEMBL Gene Tree for B3GAT2 (if available)
    TreeFam Gene Tree for B3GAT2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for B3GAT2 gene
    B3GAT12  B3GAT32  
    3 SIMAP similar genes for B3GAT2 using alignment to 2 protein entries:     B3GA2_HUMAN (see all proteins):
    DKFZp547E046    B3GAT3    B3GAT1

    Find genes that share paralogs with B3GAT2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for B3GAT2 (see all 1828)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1819868651,2
    --71572266(+) GGTATG/TTGGGG 1 -- int10--------
    rs1868764171,2
    --71572294(+) GATATA/CAGGCC 1 -- int10--------
    rs1487060561,2
    --71572415(+) CATCTA/GTAATC 1 -- int10--------
    rs1914669751,2
    --71572492(+) GCATAA/GTGAGA 1 -- int10--------
    rs1380982191,2
    C--71572513(+) CAAAA-/AATAATAC 1 -- cds10--------
    rs1422665471,2
    --71572566(+) TCCCAA/GCTACT 1 -- int10--------
    rs1179905181,2
    F--71572771(+) GCCATC/TTCAGC 1 -- int11Minor allele frequency- T:0.03NA 120
    rs1512858651,2
    --71572810(+) CCCTGC/GATCTC 1 -- int10--------
    rs20384771,2
    C,F,A,H--71573109(+) ATAACG/ATGGTA 1 -- int129Minor allele frequency- A:0.34NS EA NA CSA WA 2909
    rs1426829061,2
    C--71573372(+) CTCAA-/TGTT  
            
    TGATG
    1 -- int10--------

    HapMap Linkage Disequilibrium report for B3GAT2 (71566382 - 71666788 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for B3GAT2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2676925CNV Deletion23128226
    esv2732255CNV Deletion23290073
    nsv886148CNV Loss21882294
    nsv823726CNV Loss20364138
    esv275097CNV Loss21479260
    nsv482946CNV Gain15286789
    nsv525542CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607497    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for B3GAT2:
    Bilirubin metabolic disorder

    Find genes that share disorders with B3GAT2           About GenesLikeMe

    Genetic Association Database (GAD): B3GAT2
    Human Genome Epidemiology (HuGE) Navigator: B3GAT2 (4 documents)

    Export disorders for B3GAT2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for B3GAT2 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with B3GAT2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Crystal structure of GlcAT-S, a human glucuronyltransferase, involved in the biosynthesis of the HNK-1 carbohydrate epitope. (PubMed id 16897771)1, 2, 9 Shiba T.... Kato R. (Proteins 2006)
    2. Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients. (PubMed id 21326311)1, 4 Bhatnagar P....Keefer J.R. (J. Hum. Genet. 2011)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    6. Cloning, characterization, and chromosome mapping of the human GlcAT- S gene. (PubMed id 12522689)1, 2 Marcos I.... Antinolo G. (J. Hum. Genet. 2002)
    7. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PubMed id 11853319)1, 2 Nagase T.... Ohara O. (DNA Res. 2001)
    8. Different acceptor specificities of two glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate. (PubMed id 15470230)1, 9 Kakuda S....Kawasaki T. (Glycobiology 2005)
    9. Purification and characterization of two recombinant human glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate in Escherichia coli. (PubMed id 15039073)1, 9 Kakuda S....Kawasaki T. (Protein Expr. Purif. 2004)
    10. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 135152 HGNC: 922 AceView: B3GAT2 Ensembl:ENSG00000112309 euGenes: HUgn135152
    ECgene: B3GAT2 Kegg: 135152 H-InvDB: B3GAT2

    (According to HUGE)
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    HUGE: KIAA1963

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for B3GAT2 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=B3GAT2

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for B3GAT2 gene:
    Search GeneIP for patents involving B3GAT2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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