Aliases for B3GAT2 Gene
External Ids for B3GAT2 Gene
Previous GeneCards Identifiers for B3GAT2 Gene
The product of this gene is a transmembrane protein belonging to the glucuronyltransferase family, and catalyzes the transfer of a beta-1,3 linked glucuronic acid to a terminal galactose in different glycoproteins or glycolipids containing a Gal-beta-1-4GlcNAc or Gal-beta-1-3GlcNAc residue. The encoded protein is involved in the synthesis of the human natural killer-1 (HNK-1) carbohydrate epitope, a sulfated trisaccharide implicated in cellular migration and adhesion in the nervous system. [provided by RefSeq, Jul 2008]
GeneCards Summary for B3GAT2 Gene
B3GAT2 (Beta-1,3-Glucuronyltransferase 2) is a Protein Coding gene. Diseases associated with B3GAT2 include Colonic Benign Neoplasm. Among its related pathways are Defective B4GALT7 causes EDS, progeroid type and heparan sulfate biosynthesis. GO annotations related to this gene include galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity. An important paralog of this gene is B3GAT1.
UniProtKB/Swiss-Prot for B3GAT2 Gene
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins.