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Aliases for B3GALT5-AS1 Gene

Subcategory (RNA class) for B3GALT5-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for B3GALT5-AS1 Gene

  • B3GALT5 Antisense RNA 1 2 3 4 5
  • C21orf88 3 4
  • Chromosome 21 Open Reading Frame 88 2
  • B3GALT5 Antisense Gene Protein 1 4

External Ids for B3GALT5-AS1 Gene

Previous HGNC Symbols for B3GALT5-AS1 Gene

  • C21orf88

Summaries for B3GALT5-AS1 Gene

GeneCards Summary for B3GALT5-AS1 Gene

B3GALT5-AS1 (B3GALT5 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for B3GALT5-AS1 Gene

Genomics for B3GALT5-AS1 Gene

Regulatory Elements for B3GALT5-AS1 Gene

Enhancers for B3GALT5-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH21G039630 1.5 FANTOM5 Ensembl ENCODE dbSUPER 46.8 -19.7 -19748 5.0 CTCF JUN MNT ZBTB40 RAD21 JUND ATF3 ZNF692 GATA2 CREB1 B3GALT5-AS1 B3GALT5 ENSG00000225330 GC21P039633
GH21G039610 1.4 FANTOM5 Ensembl ENCODE 31.1 +0.8 843 3.0 SIN3A KLF17 GLIS2 ZNF366 EGR2 CEBPB ZNF518A MTA1 ZNF341 GLIS1 B3GALT5-AS1 B3GALT5 LCA5L PCP4 SH3BGR PIR53138
GH21G039636 1 ENCODE dbSUPER 35 -25.0 -24988 3.0 KLF1 NFIB KLF17 ZIC2 ZFHX2 CTBP1 GATA3 POLR2A ZNF366 ZBTB48 B3GALT5-AS1 B3GALT5 SH3BGR GC21P039633 PIR55330
GH21G039673 1.6 FANTOM5 Ensembl ENCODE dbSUPER 21.1 -62.8 -62804 3.7 CTCF PKNOX1 ESRRA FOXA2 NFIB RAD21 CTBP1 GATA3 SCRT2 SMC3 B3GALT5 B3GALT5-AS1 SH3BGR PIR55330 IGSF5
GH21G039643 0.8 ENCODE dbSUPER 34.3 -31.2 -31237 2.0 PKNOX1 GATA3 SMARCA4 EP300 FOXA1 B3GALT5-AS1 IGSF5 GC21P039633 PIR55330
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around B3GALT5-AS1 on UCSC Golden Path with GeneCards custom track

Promoters for B3GALT5-AS1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000142487 -278 1001 CTCF ZSCAN4 SIN3A RBBP5 E2F1 POLR2A ZBTB48 MTA1 ZNF341 GLIS1

Genomic Location for B3GALT5-AS1 Gene

Chromosome:
21
Start:
39,597,147 bp from pter
End:
39,612,822 bp from pter
Size:
15,676 bases
Orientation:
Minus strand

Genomic View for B3GALT5-AS1 Gene

Genes around B3GALT5-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
B3GALT5-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for B3GALT5-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for B3GALT5-AS1 Gene

Proteins for B3GALT5-AS1 Gene

  • Protein details for B3GALT5-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P59052-B3AS1_HUMAN
    Recommended name:
    Putative uncharacterized protein B3GALT5-AS1
    Protein Accession:
    P59052
    Secondary Accessions:
    • Q0VDC1
    • Q547X5

    Protein attributes for B3GALT5-AS1 Gene

    Size:
    145 amino acids
    Molecular mass:
    15706 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for B3GALT5-AS1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for B3GALT5-AS1 Gene

Post-translational modifications for B3GALT5-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for B3GALT5-AS1 Gene

Domains & Families for B3GALT5-AS1 Gene

Protein Domains for B3GALT5-AS1 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with B3GALT5-AS1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for B3GALT5-AS1 Gene

Function for B3GALT5-AS1 Gene

Phenotypes for B3GALT5-AS1 Gene

GenomeRNAi human phenotypes for B3GALT5-AS1:
genes like me logo Genes that share phenotypes with B3GALT5-AS1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for B3GALT5-AS1 Gene

Localization for B3GALT5-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for B3GALT5-AS1 gene
Compartment Confidence
extracellular 2
mitochondrion 2
peroxisome 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for B3GALT5-AS1 Gene

Pathways & Interactions for B3GALT5-AS1 Gene

SuperPathways for B3GALT5-AS1 Gene

No Data Available

Interacting Proteins for B3GALT5-AS1 Gene

Gene Ontology (GO) - Biological Process for B3GALT5-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for B3GALT5-AS1 Gene

Drugs & Compounds for B3GALT5-AS1 Gene

No Compound Related Data Available

Transcripts for B3GALT5-AS1 Gene

mRNA/cDNA for B3GALT5-AS1 Gene

(1) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for B3GALT5-AS1 Gene

No ASD Table

Relevant External Links for B3GALT5-AS1 Gene

GeneLoc Exon Structure for
B3GALT5-AS1
ECgene alternative splicing isoforms for
B3GALT5-AS1

Expression for B3GALT5-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for B3GALT5-AS1 Gene

mRNA Expression by UniProt/SwissProt for B3GALT5-AS1 Gene:

P59052-B3AS1_HUMAN
Tissue specificity: Ubiquitous.
genes like me logo Genes that share expression patterns with B3GALT5-AS1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for B3GALT5-AS1 Gene

Orthologs for B3GALT5-AS1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for B3GALT5-AS1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C21orf88 35
  • 96 (a)
OneToOne
Species where no ortholog for B3GALT5-AS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for B3GALT5-AS1 Gene

ENSEMBL:
Gene Tree for B3GALT5-AS1 (if available)
TreeFam:
Gene Tree for B3GALT5-AS1 (if available)

Paralogs for B3GALT5-AS1 Gene

No data available for Paralogs for B3GALT5-AS1 Gene

Variants for B3GALT5-AS1 Gene

Sequence variations from dbSNP and Humsavar for B3GALT5-AS1 Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type
rs1000069272 -- 39,607,747(+) TTTGG(A/G)AGGCC intron-variant
rs1000305088 -- 39,614,173(+) TTGTG(A/G)TGTTT intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1000863587 -- 39,602,305(+) TTCTG(C/T)GGGTG intron-variant
rs1001071953 -- 39,609,095(+) CTCTC(A/G)CCCTT intron-variant
rs1001128577 -- 39,608,427(+) TTGGT(A/T)TTTCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for B3GALT5-AS1 Gene

Variant ID Type Subtype PubMed ID
esv27418 CNV gain 19812545
esv34779 CNV gain 17911159
esv3568195 CNV loss 25503493
esv3647020 CNV gain 21293372
nsv1061454 CNV gain 25217958
nsv478120 CNV novel sequence insertion 20440878
nsv587484 CNV loss 21841781

Variation tolerance for B3GALT5-AS1 Gene

Gene Damage Index Score: 1.47; 28.64% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for B3GALT5-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
B3GALT5-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for B3GALT5-AS1 Gene

Disorders for B3GALT5-AS1 Gene

Relevant External Links for B3GALT5-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
B3GALT5-AS1

No disorders were found for B3GALT5-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for B3GALT5-AS1 Gene

Publications for B3GALT5-AS1 Gene

  1. Nineteen additional unpredicted transcripts from human chromosome 21. (PMID: 12036297) Reymond A. … Antonarakis S.E. (Genomics 2002) 2 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters. (PMID: 20494980) Warnatz H.J. … Yaspo M.L. (Nucleic Acids Res. 2010) 3 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for B3GALT5-AS1 Gene

Sources for B3GALT5-AS1 Gene

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