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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

B3GALT5 Gene

protein-coding GIFtS: 55
GCID: GC21P040928

UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide...

Explore 5 diseases affiliated with
B3GALT5 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, and/or ¹¹Nature:405,311-319 and CroW21)
About This Section

Aliases
UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide 5¹ ²		B3GalTx²
GLCT5¹ ² ⁵		Beta-1,3-Galactosyltransferase 5²
B3GalT-V¹ ²		Beta-3-Gx-T5³
B3T5¹ ²		Beta3GalT5³
Beta3Gal-T5³		Homolog Of C. Elegans Bt Toxin Resistance Gene Bre-5²
GlcNAc-Beta-1,3-Galactosyltransferase 5² 11		Beta-3-Gx-T5³
Beta-1,3-GalTase 5² ³		Beta3Gal-T5³
B3Gal-T5¹		Beta3GalT5³
UDP-Gal:Beta-GlcNAc Beta-1,3-Galactosyltransferase 5² ³		EC 2.4.1.-³
UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,3-Galactosyltransferase 5² ³		EC 2.4.1⁸

External Ids:	HGNC: 920¹	Entrez Gene: 10317²	Ensembl: ENSG00000183778⁷	OMIM: 604066⁵	UniProtKB: Q9Y2C3³

Export aliases for B3GALT5 gene to outside databases

Previous GC identifers: GC21P037603 GC21P039950 GC21P039949 GC21P039951 GC21P026498

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for B3GALT5:

This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II

membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and

UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The

beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained

in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT

proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes

synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence

similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3,

beta3GalT5). This gene encodes the most probable candidate for synthesis of the type 1 Lewis antigens which are

frequently found to be elevated in gastrointestinal and pancreatic cancers. The encoded protein is inactive with

N-linked glycoproteins and functions in mucin glycosylation. Alternatively spliced transcript variants encoding the

same protein have been observed for this gene. (provided by RefSeq, Jul 2012)

UniProtKB/Swiss-Prot: B3GT5_HUMAN, Q9Y2C3

Function: Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan

GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor

Gene Wiki entry for B3GALT5

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics, Whole Chromsome Sequence According to Nature (Cited Here with Permission):405,311-319 and CroW21)
About This Section

RefSeq DNA sequence:

NC_000021.8 NC_018932.1 NT_011512.11

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the B3GALT5 gene promoter:
Max1 RP58 p53 Lmo2 FOXL1 RORalpha1 SRY Sox9 c-Myc ATF6
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: B3GALT5 promoter sequence

Search SABiosciences Chromatin IP Primers for B3GALT5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B3GALT5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.3 Ensembl cytogenetic band: 21q22.2 HGNC cytogenetic band: 21q22.3
Nature(405: 311-319) cytogenetic band: 21q22.2

B3GALT5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B3GALT5 gene location

GeneLoc information about chromosome 21 GeneLoc Exon Structure

(about GC identifiers)

GC21P040928:	GeneLoc	Nature:405,311-319
Start:	40,928,369 bp from pter	26,602,223 bp from centromere
End:	41,034,816 bp from pter	26,607,784 bp from centromere
Size:	106,448 bases	5,562 bases
Orientation:	plus strand	plus strand

Whole chromosome sequencing:
cDNA sequence:	AB020337
genomic clones:	P70I24

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: B3GT5_HUMAN, Q9Y2C3 (See protein sequence)

Recommended Name: Beta-1,3-galactosyltransferase 5

Size: 310 amino acids; 36189 Da

Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (Potential)

Secondary accessions: A8KA86 D3DSI3 Q2M3L5 Q53Z19 Q9NY96 Q9P1X6 Q9P1X7

Explore the universe of human proteins at neXtProt for B3GALT5: NX_Q9Y2C3

4/8 DME Specific Peptides for B3GALT5 (Q9Y2C3) (see all 8)

VMKTDSD

TTRFFTG

FCSGTGY

AIRQTWG

B3GALT5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (4 alternative transcripts):

NP_006048.1 NP_149360.1 NP_149361.1 NP_149362.1

ENSEMBL proteins:

ENSP00000369994 ENSP00000369992 ENSP00000343318 ENSP00000381699

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Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	IEA	--
GO:0005783	endoplasmic reticulum	IDA	16780588
GO:0005794	Golgi apparatus	IDA	16780588
GO:0016021	integral to membrane	IEA	--

B3GALT5 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

B3GALT5 for domains About GeneDecksing

1 InterPro domain/family:

IPR002659 Glyco_trans_31

Graphical View of Domain Structure for InterPro Entry Q9Y2C3

ProtoNet protein and cluster: Q9Y2C3

1 Blocks protein family: IPB002659 Glycosyl transferase

UniProtKB/Swiss-Prot: B3GT5_HUMAN, Q9Y2C3

Similarity: Belongs to the glycosyltransferase 31 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: B3GT5_HUMAN, Q9Y2C3

Function: Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan

GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor

Genatlas biochemistry entry for B3GALT5:

UDP galactose

Enzyme Numbers (IUBMB): EC 2.4.1² EC 2.4.1.-¹

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	TAS	10212226

B3GALT5 for ontologies About GeneDecksing

Phenotypes:
1 MGI mutant phenotype (inferred from 1 allele) (MGI details for B3galt5):

normal

B3GALT5 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for B3GALT5

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B3GALT5

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Glycosphingolipid biosynthesis - lacto and neolacto series

Glycosphingolipid biosynthesis - lacto and neolacto series

1.00

Glycosphingolipid biosynthesis - globo series

Glycosphingolipid biosynthesis - globo series

1.00

Metabolism

Metabolic pathways

0.38

Pathway sources
See GeneCards unified pathways
Show all pathways

3 Kegg Pathways (Kegg details for B3GALT5):

	Glycosphingolipid biosynthesis - lacto and neolacto series
	Glycosphingolipid biosynthesis - globo series
	Metabolic pathways

UniProtKB/Swiss-Prot: B3GT5_HUMAN, Q9Y2C3

Pathway: Protein modification; protein glycosylation

B3GALT5 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for B3GALT5

STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

5/17 Interacting proteins for B3GALT5 (ENSP00000343318⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 17)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
B3GALNT1	ENSP00000323479⁴	STRING: ENSP00000323479
B4GALT1	ENSP00000369055⁴	STRING: ENSP00000369055
FUT1	ENSP00000312021⁴	STRING: ENSP00000312021
FUT2	ENSP00000375748⁴	STRING: ENSP00000375748
FUT3	ENSP00000305603⁴	STRING: ENSP00000305603

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006486	protein glycosylation	IEA	--

B3GALT5 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for B3GALT5

10/519 HMDB Compounds for B3GALT5 (see all 519) About this table

Compound	Synonyms	CAS #	PubMed Ids
3-Dehydrosphinganine	1-Hydroxy-2-amino-3-oxo-octadecane (see all 9)	16105-69-4	--
3-O-Sulfogalactosylceramide (d18:1/12:0)	Sulfatide (d18:1/12:0) (see all 13)	852100-88-0	--
3-O-Sulfogalactosylceramide (d18:1/14:0)	Sulfatide (d18:1/14:0) (see all 13)	--	--
3-O-Sulfogalactosylceramide (d18:1/16:0)	Sulfatide (d18:1/16:0) (see all 13)	862509-48-6	--
3-O-Sulfogalactosylceramide (d18:1/18:0)	Sulfatide (d18:1/18:0) (see all 13)	244215-65-4	--
3-O-Sulfogalactosylceramide (d18:1/18:1(9Z))	Sulfatide (d18:1/18:1(9Z)) (see all 13)	--	--
3-O-Sulfogalactosylceramide (d18:1/20:0)	Sulfatide (d18:1/20:0) (see all 13)	265096-81-9	--
3-O-Sulfogalactosylceramide (d18:1/22:0)	Sulfatide (d18:1/22:0) (see all 13)	265096-83-1	--
3-O-Sulfogalactosylceramide (d18:1/24:0)	Sulfatide (d18:1/24:0) (see all 16)	151122-71-3	--
3-O-Sulfogalactosylceramide (d18:1/24:1(15Z))	Sulfatide (d18:1/24:1(15Z)) (see all 13)	151057-28-2	--

Search CenterWatch for drugs/clinical trials and news about B3GALT5 / B3GT5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for B3GALT5 gene (5 alternative transcripts):

NM_006057.1 NM_033170.1 NM_033171.1 NM_033172.1 NM_033173.1

Unigene Cluster for B3GALT5:

UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5

Hs.733638 [show with all ESTs]

Unigene Representative Sequence: AY372061

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000380620(uc002yyf.1 uc002yyg.1 uc002yyh.1 uc002yyb.1)

ENST00000475838 ENST00000380618(uc002yyi.1 uc002yyj.1 uc002yyk.1 uc002yyl.1 uc002yym.1)

ENST00000343118(uc010gom.1 uc002yye.2) ENST00000398714

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Additional cDNA sequence:

AB020337.1 AK292951.1 AY372061.1 BC104862.1 BC104864.1 DQ645732.1 DQ645733.1 DQ645734.1

DQ645735.1 DQ645736.1 DQ645737.1 DQ645738.1

5 DOTS entries:

DT.100017759 DT.70100727 DT.121129535 DT.100017758 DT.101979765

14 AceView cDNA sequences:

NM_006057 NM_033170 AY372061 AW136254 NM_033173 NM_033172 AB020337 NM_033171

BM715577 BX281941 AI739518 BM674032 BF366265 AU100432

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

B3GALT5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

B3GALT5 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Ovary

Ovary

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See B3GALT5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for B3GALT5

SOURCE GeneReport for Unigene cluster: Hs.733638

UniProtKB/Swiss-Prot: B3GT5_HUMAN, Q9Y2C3

Tissue specificity: Expressed in stomach, jejunum, colon, pancreas, small intestine, testis and gastrointestinal and

pancreatic cancer cell lines. Hardly detected in lung, liver, adrenal gland and peripheral blood leukocytes

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B3GALT5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for B3GALT5 gene from 6/18 species (see all 18) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	B3GALT5¹	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, more	64.61(n) 62.93(a)		427985 XM_425555.3 XP_425555.3
lizard (Anolis carolinensis)	Reptilia	-- --	--	61(a) 51(a)	1 ↔ many 1 ↔ many	3(139533568-139534482) 3(139511258-139513504)
African clawed frog (Xenopus laevis)	Amphibia	Xl.16252²	Xenopus laevis transcribed sequence with weak similarity more	74.38(n)		BJ632719.1
fruit fly (Drosophila melanogaster)	Insecta	CG8668³ CG8673¹	UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase³ CG8673¹	35(a) (best of 2)³ 49.78(n)¹ 40.97(a)¹		28E7³ 34105¹ NM_135338.2¹ NP_609182.1¹
thale cress (Arabidopsis thaliana)	eudicotyledons	AT3G06440¹	putative beta-1,3-galactosyltransferase 16	41.49(n) 31.54(a)		819820 NM_111519.2 NP_566284.1
rice (Oryza sativa)	Liliopsida	Os01g0328900¹	hypothetical protein	42.15(n) 29.75(a)		4326981 NM_001049454.1 NP_001042919.1

ENSEMBL Gene Tree for B3GALT5 (if available)
TreeFam Gene Tree for B3GALT5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for B3GALT5 gene

B3GNT3² B3GNT2² B3GNT5² B3GALT1² B3GNT4² B3GALT4² B3GNT7² B3GALT2²

B3GNT8² B3GNT6² B3GALNT1² B3GNT9²

9 SIMAP similar genes for B3GALT5 using alignment to 1 protein entry: B3GT5_HUMAN:

OK/KNS-cl.1 B3GALT2 B3GALNT1 B3GALT1 B3GNT5 B3GNT3

B3GNT6 B3GNT8 B3GNT7

B3GALT5 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
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SNP ID	Valid	Clinical significance	Chr 21 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs73215502^1,2	C	--	26498877(+)	`TATCTG/ATCTGT`	1	--	int¹		1		CSA	2
rs186017212^1,2		--	41027441(+)	`TTCTTA/CATTAC`	4	--	us2k¹		0	--	--	--	--
rs146870154^1,2		--	41027505(+)	`TTGAGC/GCCAGG`	4	--	us2k¹		0	--	--	--	--
rs2239385^1,2	C,F,A,H	--	41027747(+)	`GACACA/GGGAGT`	4	--	us2k¹		36		EA NS NA WA CSA	4639
rs2239386^1,2	C,F,A,H	--	41027823(+)	`CCTTCT/CCCAGG`	4	--	us2k¹		10		EA NA WA CSA	1878
rs11088491^1,2	C,F,A,H	--	41027854(+)	`GTACAA/GCGAAT`	4	--	us2k¹		11		EA NA	618
rs16998087^1,2	C,F	--	41027864(+)	`TCCACT/GGAAAT`	4	--	us2k¹		8		NA WA CSA	267
rs140704392^1,2		--	41027902(+)	`CTTCGA/GCCTTG`	4	--	us2k¹		0	--	--	--	--
rs144542939^1,2		--	41028079(+)	`CAAGCC/TTCCCG`	4	--	us2k¹		0	--	--	--	--
rs76227264^1,2		--	41028141(+)	`AGGGAC/TGTTGA`	4	--	us2k¹		1		NA	120

HapMap Linkage Disequilibrium report for B3GALT5 (40928369 - 41034816 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for B3GALT5: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing B3GALT5

DNA2.0 Custom Variant and Variant Library Synthesis for B3GALT5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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B3GALT5 for disorders           About GeneDecksing

OMIM gene information: 604066    OMIM disorders: --

5 diseases for B3GALT5:    About MalaCards

pancreatic cancer pancreatitis colon carcinoma immunodeficiency

carcinoma

Human Genome Epidemiology (HuGE) Navigator: B3GALT5 (1 document)

Export disorders for B3GALT5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for B3GALT5 gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with B3GALT5)

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Cloning, expression, and characterization of a novel UDP- galactose:beta-N-acetylglucosamine beta1,3-galactosyltransferase (beta3Gal-T5) responsible for synthesis of type 1 chain in colorectal and pancreatic epithelia and tumor cells derived therefrom. (PubMed id 10212226)^{1, 2, 3, 9} Isshiki S....Narimatsu H. (1999)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
An endogenous retroviral long terminal repeat is the dominant promoter for human beta1,3-galactosyltransferase 5 in the colon. (PubMed id 14534330)^{1, 2} Dunn C.A.... Mager D.L. (2003)
The DNA sequence of human chromosome 21. (PubMed id 10830953)^{1, 2} Hattori M....Yaspo M.L. (2000)
Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. (PubMed id 10580128)^{1, 2} Amado M.... Clausen H. (1999)
Molecular cloning of a human UDP-galactose:GlcNAcbeta1,3GalNAc beta1, 3 galactosyltransferase gene encoding an O-linked core3-elongation enzyme. (PubMed id 10406968)^{1, 2} Zhou D.... Hennet T. (1999)
DNA methylation and histone modifications modulate the b1,3 galactosyltransferase b3Gal-T5 native promoter in cancer cells. (PubMed id 22001559)¹ Caretti A....Trinchera M. (2012)
Functional analysis and identification of cis-regulat ory elements of human chromosome 21 gene promoters. (PubMed id 20494980)¹ Warnatz H.J....Yaspo M.L. (2010)
Genetic utility of broadly defined bipolar schizoaffe ctive disorder as a diagnostic concept. (PubMed id 19567891)¹ Hamshere M.L....McGuffin P. (2009)
Enhanced expression of beta 3-galactosyltransferase 5 activity is sufficient to induce in vivo synthesis of extended type 1 chains o n lactosylceramides of selected human colonic carcinoma cell lines. (PubMed id 19136585)¹ Lin C.H....Khoo K.H. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10317	HGNC: 920	AceView: B3GALT5	Ensembl:ENSG00000183778	euGenes: HUgn10317
ECgene: B3GALT5	Kegg: 10317	H-InvDB: B3GALT5

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for B3GALT5	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for B3GALT5	Genetics and Cytogenetics in Oncology and Haematology
GGDB	http://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=B3GALT5
Functional Glycomics Gateway - GTase	http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_432

Intellectual Property for B3GALT5 gene
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Patent Information for B3GALT5 gene:
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B3GALT5 Gene

UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide...

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B3GALT5 (Gene Symbol)
UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide 5
GLCT5
B3GalT-V
B3T5
Beta3Gal-T5
GlcNAc-Beta-1,3-Galactosyltransferase 5
Beta-1,3-GalTase 5
B3Gal-T5
UDP-Gal:Beta-GlcNAc Beta-1,3-Galactosyltransferase 5
UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,3-Galactosyltransferase 5
B3GalTx
Beta-1,3-Galactosyltransferase 5
Beta-3-Gx-T5
Beta3GalT5
Homolog Of C. Elegans Bt Toxin Resistance Gene Bre-5
Beta-3-Gx-T5
Beta3Gal-T5
Beta3GalT5
EC 2.4.1.-
EC 2.4.1

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B3GALT5 Gene

UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide...

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