Aliases for B3GALT4 Gene
- Beta-1,3-Galactosyltransferase 4 2 3 5
- UDP-Galactose:Beta-N-Acetyl-Galactosamine-Beta-1,3-Galactosyltransferase 3 4
- UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide 4 2 3
- UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase 4 2 3
- Ganglioside Galactosyltransferase 3 4
- Beta-1,3-GalTase 4 3 4
- EC 220.127.116.11 4 63
- BETA3GALT4 3 4
External Ids for B3GALT4 Gene
Previous GeneCards Identifiers for B3GALT4 Gene
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for B3GALT4 Gene
B3GALT4 (Beta-1,3-Galactosyltransferase 4) is a Protein Coding gene. Among its related pathways are Glycosphingolipid biosynthesis - ganglio series and Metabolism. GO annotations related to this gene include galactosyltransferase activity and ganglioside galactosyltransferase activity. An important paralog of this gene is B3GNT5.
UniProtKB/Swiss-Prot for B3GALT4 Gene
Involved in GM1/GD1B/GA1 ganglioside biosynthesis.