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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

B3GALT4 Gene

protein-coding   GIFtS: 54
GCID: GC06P033244

UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide...

 Explore 15 diseases affiliated with
B3GALT4 via our new
 Human Malady Compendium 
Biological research products
for B3GALT4
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide 41 2     BETA3GALT42
GalT41 3     GALT22
Beta-1,3-GalTase 42 3     Beta-1,3-Galactosyltransferase 42
Ganglioside Galactosyltransferase2 3     Beta-3-Galactosyltransferase 42
GALT42 3     Gal-T23
UDP-Galactose:Beta-N-Acetyl-Galactosamine-Beta-1,3-Galactosyltransferase1     Beta3Gal-T43
B3Gal-T41     Beta3GalT43
EC 2.4.1.623 8     Gal-T23
Beta3Gal-T43     

External Ids:    HGNC: 9191   Entrez Gene: 87052   Ensembl: ENSG000002358637   OMIM: 6030955   UniProtKB: O960243   

Export aliases for B3GALT4 gene to outside databases

Previous GC identifers: GC06U990168 GC06P033241 GC06P033237 GC06P033291 GC06P033252 GC06P033352 GC06P032986


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for B3GALT4:
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II
membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and
UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The
beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained
in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT
proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes
synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence
similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3,
beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The
functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis. (provided by RefSeq, Jul
2008)

UniProtKB/Swiss-Prot: B3GT4_HUMAN, O96024
Function: Involved in GM1/GD1B/GA1 ganglioside biosynthesis

Gene Wiki entry for B3GALT4


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  NT_113891.2  NT_167245.1  NT_167247.1  NT_167248.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the B3GALT4 gene promoter:
         ER-alpha   TBP   p53   AP-1   Olf-1   Meis-1b   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidB3GALT4 promoter sequence
   Search SABiosciences Chromatin IP Primers for B3GALT4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B3GALT4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p21.32   HGNC cytogenetic band: 6p21.3

B3GALT4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B3GALT4 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P033244:  view genomic region     (about GC identifiers)

Start:
33,244,917 bp from pter      End:
33,246,602 bp from pter
Size:
1,686 bases      Orientation:
plus strand

4 alternative locations:
Chr6+,ALT_REF_LOCI_5 33,330,114-33,331,799      Chr6+,ALT_REF_LOCI_3 33,222,842-33,235,565      Chr6+,ALT_REF_LOCI_2 33,166,523-33,207,396     
Chr6+,ALT_REF_LOCI_6 33,173,759-33,211,025     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: B3GT4_HUMAN, O96024 (See protein sequence)
Recommended Name: Beta-1,3-galactosyltransferase 4  
Size: 378 amino acids; 41537 Da
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein

Explore the universe of human proteins at neXtProt for B3GALT4: NX_O96024

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O96024

  • 4/6 DME Specific Peptides for B3GALT4 (O96024) (see all 6)
     NLTLKTL  MQEAWKLV  PLLYLGRVHWRV  GEELLSLSLASL 

    B3GALT4 Protein expression data from MOPED and PaxDb:    About this image 
    B3GALT4 Protein Expression
    REFSEQ proteins: NP_003773.1  
    ENSEMBL proteins: 
     ENSP00000390784  

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    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0016021integral to membrane IEA--

    B3GALT4 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    B3GALT4 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR002659 Glyco_trans_31

    Graphical View of Domain Structure for InterPro Entry O96024

    ProtoNet protein and cluster: O96024

    1 Blocks protein family: IPB002659 Glycosyl transferase

    UniProtKB/Swiss-Prot: B3GT4_HUMAN, O96024
    Similarity: Belongs to the glycosyltransferase 31 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: B3GT4_HUMAN, O96024
    Function: Involved in GM1/GD1B/GA1 ganglioside biosynthesis
    Catalytic activity: UDP-alpha-D-galactose + an
    N-acetyl-beta-D-galactosaminyl-(1->4)-(alpha-N-acetylneuraminyl-(2->3))-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
    = UDP + a
    beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-(alpha-N-acetylneuraminyl-(2->3))-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

         Genatlas biochemistry entry for B3GALT4:
    UDP galactose

         Enzyme Number (IUBMB): EC 2.4.1.621 2

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008499UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity TAS9582303
    GO:0047915ganglioside galactosyltransferase activity IEA--
         
    B3GALT4 for ontologies           About GeneDecksing


    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Ganglio Sphingolipid Metabolism
    Ganglio Sphingolipid Metabolism1.00
    Glycosphingolipid biosynthesis - ganglio series0.53
    2Metabolism
    Metabolic pathways0.38

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for B3GALT4 
        Ganglio Sphingolipid Metabolism


    2         Kegg Pathways  (Kegg details for B3GALT4):
        Glycosphingolipid biosynthesis - ganglio series
    Metabolic pathways

    UniProtKB/Swiss-Prot: B3GT4_HUMAN, O96024
    Pathway: Protein modification; protein glycosylation


    B3GALT4 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for B3GALT4

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5 Interacting proteins for B3GALT4 (O960242, 3 ENSP000003907844) via UniProtKB, MINT, STRING, and/or I2D

    InteractantInteraction Details
    GeneCardExternal ID(s)
    DYNLL1P631672, 3MINT-8249201 I2D: score=2 
    METTL18O955682, 3MINT-8249190 I2D: score=2 
    DDX19BQ9UMR23, ENSP000002880714I2D: score=3 STRING: ENSP00000288071
    --Q7Z4W53I2D: score=1 
    --Q96KE72MINT-65227
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006486protein glycosylation IEA--

    B3GALT4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    B3GALT4 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for B3GALT4

    10/62 HMDB Compounds for B3GALT4 (see all 62)    About this table
    CompoundSynonyms CAS #PubMed Ids
    Ganglioside GM1 (d18:0/12:0) --12486725
    Ganglioside GM1 (d18:0/14:0) --12486725
    Ganglioside GM1 (d18:0/16:0) --12486725
    Ganglioside GM1 (d18:0/18:0) --12486725
    Ganglioside GM1 (d18:0/18:1(11Z)) --12486725
    Ganglioside GM1 (d18:0/18:1(9Z)) --12486725
    Ganglioside GM1 (d18:0/20:0) --12486725
    Ganglioside GM1 (d18:0/22:0) --12486725
    Ganglioside GM1 (d18:0/22:1(13Z)) --12486725
    Ganglioside GM1 (d18:0/23:0) --12486725
    10/11 Novoseek chemical compound relationships for B3GALT4 gene (see all 11)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    laccer 94.8 9 11740154 (2), 15229397 (2), 12900410 (1), 8481397 (1) (see all 7)
    lactosylceramide 93.4 8 8808768 (1), 11740154 (1), 8481397 (1), 9343929 (1) (see all 7)
    glucosylceramide 88.2 10 8808768 (1), 9061365 (1), 11740154 (1), 8781979 (1) (see all 6)
    glycosphingolipid 86.3 3 11740154 (1), 8481397 (1)
    ceramide 67.6 2 11740154 (1), 1834652 (1)
    ganglioside 66.9 6 8536214 (1), 8005614 (1), 9582303 (1)
    udpglucose 65.4 4 9061365 (1), 8781979 (1), 1551920 (1)
    galactose 32.8 1 8005614 (1)
    gtp 29.4 1 9254052 (1)
    lipid 1.29 4 2129343 (2), 15229397 (1)

    Search CenterWatch for drugs/clinical trials and news about B3GALT4 / B3GT4 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for B3GALT4 gene: 
    NM_003782.3  

    Unigene Cluster for B3GALT4:

    UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
    Hs.534375  [show with all ESTs]
    Unigene Representative Sequence: NM_003782
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000451237(uc003odr.3)

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    Additional cDNA sequence: 

    AB026730.1 AF063595.1 AK075312.1 AK315647.1 BC032574.1 CR457093.1 Y15061.1 

    3 DOTS entries:

    DT.92419828  DT.210266  DT.97788718 

    24/2732 AceView cDNA sequences (see all 2732):

    BM511038 CR605901 BU196292 BQ642996 BM784786 BM554157 BU627674 AI718583 
    N86003 AJ710139 BI753287 CA414531 AA353470 CN483067 BM479799 F25826 
    BM670395 CR619620 BQ058589 BU508594 AW167536 BM991507 BG030747 BM849722 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    B3GALT4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCCCGATACG
    B3GALT4 Expression
    About this image
    See B3GALT4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for B3GALT4

    SOURCE GeneReport for Unigene cluster: Hs.534375

    UniProtKB/Swiss-Prot: B3GT4_HUMAN, O96024
    Tissue specificity: Highly expressed in heart, skeletal muscle and pancreas and, to a lesser extent, in brain,
    placenta, kidney, liver and lung

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for B3GALT4 gene from 7/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves B3GALT46
    Uncharacterized protein
    25(a)
    1 ↔ 1
    17(8968571-8970633)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    --
    40(a)
    39(a)
    (see all 3)
    1 ↔ many
    1 ↔ many
    (see all 3)
    GL343964.1(94653-95672)
    GL343520.1(383335-384935)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.45522 Xenopus laevis transcribed sequence with strong similarity more 82.64(n)    48037142 
    zebrafish
    (Danio rerio)
    Actinopterygii rps182 ribosomal protein S18 81.86(n)   192300  AY099517.1 
    worm
    (Caenorhabditis elegans)
    Secernentea bus-176
    Bacterially Un-Swollen (M. nematophilum resistant)...
    17(a)
    1 ↔ 1
    X(15757800-15766272)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G210606
    AT3G064406
    (see all 6)
    putative beta-1,3-galactosyltransferase 16
    (see all 6)
    9(a)
    12(a)
    (see all 6)
    many ↔ many
    many ↔ many
    (see all 6)
    4(11240730-11245049)
    3(1972622-1975754)
    rice
    (Oryza sativa)
    Liliopsida Os.254872 Transcribed sequence with weak similarity to protein more 76.71(n)    CA767430.2 


    ENSEMBL Gene Tree for B3GALT4 (if available)
    TreeFam Gene Tree for B3GALT4 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for B3GALT4 gene
    B3GNT32  B3GNT22  B3GNT52  B3GALT52  B3GALT12  B3GNT42  B3GALT22  B3GNT72  
    B3GNT82  B3GNT62  B3GALNT12  B3GNT92  
    1 SIMAP similar gene for B3GALT4 using alignment to 2 protein entries:     B3GT4_HUMAN (see all proteins):
    B3GALT1

    B3GALT4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/56 NCBI SNPs in B3GALT4 are shown (see all 56    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs726544851,2
    F--33244782(+) GCTGGA/TCAGAC 1 -- us2k11Minor allele frequency- T:0.02NS 736
    rs1928169021,2
    --33244800(+) ACTCCA/GTTTGG 1 -- us2k10--------
    rs726544871,2
    C,F--33244810(+) GTGCCA/CCTCCA 1 -- us2k12Minor allele frequency- C:0.01NS WA 878
    rs726544881,2
    C,F--33244814(+) CACTCC/TACCCG 1 -- us2k12Minor allele frequency- T:0.01NS WA 878
    rs797687311,2
    C--33244853(+) TCCGAC/TGCCGC 1 -- us2k10--------
    rs1852940691,2
    --33245075(+) GGTCCC/GGGTCG 1 -- ut510--------
    rs726544901,2
    C,F--33245205(+) CAGCTC/GAGGCT 2 L syn13Minor allele frequency- G:0.01NS WA NA 4550
    rs2019121531,2
    --33245259(+) TGGACC/TCTCTT 2 T syn10--------
    rs22312591,2
    C--33245355(+) GCCCTG/TCCCCG 2 L syn10--------
    rs1417844441,2
    F--33245397(+) GGTCCC/TGGGGC 2 P syn11Minor allele frequency- T:0.00NA 2554

    HapMap Linkage Disequilibrium report for B3GALT4 (33244917 - 33246602 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for B3GALT4: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing B3GALT4
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    B3GALT4 for disorders           About GeneDecksing

    OMIM gene information: 603095    OMIM disorders: --

    15 diseases for B3GALT4:    About MalaCards
    uterine corpus cancer    systemic lupus erythematosus    polycystic kidney disease    lupus erythematosus
    kidney disease    diphtheria    acne    atherosclerosis
    meningioma    breast carcinoma    cholesterol    neuroblastoma
    immunodeficiency    melanoma    carcinoma

    1 disease from the University of Copenhagen DISEASES database for B3GALT4:
    Uterine corpus cancer

    2 Novoseek disease relationships for B3GALT4 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    atherosclerosis 35.7 1 15229397 (1)
    tumors 0 2 8481397 (2)

    Human Genome Epidemiology (HuGE) Navigator: B3GALT4 (2 documents)

    Export disorders for B3GALT4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for B3GALT4 gene, integrated from 9 sources (see all 41):
    (articles sorted by number of sources associating them with B3GALT4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta- nacetyl-galactosamine beta-1,3-galactosyltransferase family. (PubMed id 9582303)1, 2, 3, 9 Amado M.... Clausen H. (1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    4. The beta 1,3-galactosyltransferase-4 (b3Gal-T4) gene is located in the centromeric segment of the human MHC class II region. (PubMed id 10663566)1, 2 Shiina T.... Inoko H. (2000)
    5. Induction of GM1a/GD1b synthase triggers complex gang lioside expression and alters neuroblastoma cell behavior; a new tumor cell mod el of ganglioside function. (PubMed id 21519903)1 Dong L....Ladisch S. (2011)
    6. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    7. GM1a88/a88GD1ba88/a88GA1 synthase expression results in the r educed cancer phenotypes with modulation of composition and raft-localization o f gangliosides in a melanoma cell line. (PubMed id 20594196)1 Dong Y....Furukawa K. (2010)
    8. High-density SNP screening of the major histocompatib ility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1 Barcellos L.F....Criswell L.A. (2009)
    9. Beta1,3-galactosyltransferases-4/5 are novel tumor markers for gynecological cancers. (PubMed id 19225246)1 Seko A....Yamashita K. (2009)
    10. Comparison of HPLC/ESI-FTICR MS versus MALDI-TOF/TOF M S for glycopeptide analysis of a highly glycosylated HIV envelope glycoprotein. (PubMed id 18565761)1 Irungu J....Desaire H. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8705 HGNC: 919 AceView: B3GALT4andRPS18andD6S2723E Ensembl:ENSG00000235863 euGenes: HUgn8705
    ECgene: B3GALT4 Kegg: 8705 H-InvDB: B3GALT4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for B3GALT4 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=B3GALT4
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_431

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for B3GALT4 gene:
    Search GeneIP for patents involving B3GALT4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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